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来自一项艾日布林联合吉西他滨对比紫杉醇联合吉西他滨作为HER2阴性转移性乳腺癌的一线化疗的Ⅱ期、多中心、随机试验的包含神经病变相关量表的生活质量结果：韩国癌症研究组试验(KCSG BR13-11)

癌症 2019年第8期38卷 368-376页

作者： Ji‑Yeon Kim Seri Park Seock‑Ah Im Sung‑Bae Kim Joohyuk Sohn Keun Seok Lee Yee soo Chae Ki Hyeong Lee Jee Hyun Kim young‑Hyuck Im Tae‑Yong Kim Kyung‑Hun Lee Jin‑Hee Ahn Gun Min Kim In Hae Park soo Jung Lee Hye sook Han Se Hyun Kim Kyung Hae Jung Yeon Hee Park Korean Cancer Study Group Division of Hematology‑Oncology Department of MedicineSamsung Medical CenterSungkyunkwan University School of Medicine81 Irwon‑roGangnam‑guSeoul 06351South Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and TechnologySungkyunkwan UniversitySeoul 06351South Korea Department of Internal Medicine Seoul National University HospitalCancer Research InstituteCollege of MedicineSeoul National UniversitySeoul 03080South Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Medical Oncology Department of Internal MedicineYonsei University College of MedicineSeoul 03722South Korea Center for Breast Cancer National Cancer CenterGoyang 10408South Korea Department of Internal Medicine Kyungpook National University HospitalDaegu 41944South Korea Deparment of Internal Medicine Chungbuk National University HospitalCheongju 28644South Korea Department of Internal Medicine Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnam 13620South Korea 不详

背景与目的一项比较艾日布林联合吉西他滨(eribulin plus gemcitabine,EG)或紫杉醇联合吉西他滨(paclitaxel plus gemcitabine,PG)作为转移性乳腺癌(metastatic breast cancer,MBC)患者一线化疗方案的II期临床试验发现,EG方案的神经毒性较低,但疗效与PG方案相似。在本研究中,我们分析了该临床实验中的癌症患者生命质量测评量表–紫杉烷(functional assessment of cancer therapy-taxane,FACT-Taxane)问卷评分以确定他们的生活质量(quality of life,QoL)。方法使用韩国版的FACT-Taxane问卷评估QoL。在评估基线之后,前12个疗程中每2个疗程评估1次QoL,之后每3个疗程评估1次QoL。使用线性混合模型评估EG组和PG组QoL的差异。结果在118例入组患者中,117例在基线时回复了FACT-Taxane问卷,PG组中有1例患者没有回复。EG组和PG组之间的基线QoL评分没有差异。在治疗期间,除了第11个疗程外,在第2–13个化疗疗程后,PG组紫杉烷亚量表评分显著高于EG组(均P<0.05)。神经病变特异性分析显示PG组患者的神经病症状比EG组患者更早出现且更严重(P<0.001)。结论在我们的QoL分析中,与PG方案相比,EG方案延迟并减少神经病变的发生。因此,艾日布林是MBC一线化疗药物紫杉醇的合理替代品。

关键词：转移性乳腺癌艾日布林紫杉醇神经病生活质量癌症患者生命质量测评量表–紫杉烷问卷

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Influences of tool plunge speed and tool plunge depth on friction spot joining of AA5454-O aluminum alloy plates with different thicknesses

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中国有色金属学会会刊：英文版 2012年第S3期22卷 629-633页

作者： Sung-Ook YOON Myoung-soo KANG Yong-Jai KWON Sung-Tae HONG Dong-Hwan PARK Kwang-Hak LEE Chang-Yong LIM Jong-Dock SEO School of Materials Science and Engineering University of Ulsan School of Mechanical Engineering University of Ulsan Institute of E-Vehicle Technology University of Ulsan Technical Research Laboratories Shin Young Co.Ltd.

AA5454-O aluminum alloy plates with the thicknesses of 1.4 and 1.0 mm were friction-spot-joined (FSJed).The plunge speed of the joining tool was changed in a range of 100 500 mm/min under a constant rotation speed of 500 r/*** plunge depth was ranged from 1.6 mm to 2.2 *** tool plunge speed did not make a remarkable effect on the surface appearance and macro-structure of the FSJed *** average hardness of the FSJed zone was greater than or equal to that of the base ***,there was no remarkable tendency in the average hardness change of the FSJed zone in spite of the variation in the tool plunge speed and tool plunge *** increase of the tool plunge depth resulted in the increase of the tensile shear ***,the change of the tool plunge speed did not lead to the remarkable variation in the tensile shear load of the FSJed *** was noteworthy that the FSJed plate exhibited the highest tensile shear load of about 4.0 kN.

关键词： friction spot joining AA5454-O aluminum alloy plunge speed plunge depth mechanical property

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别有洞天——首尔PANAM旗舰店

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现代装饰 2022年第6期 24-29页

作者： Sung chul Park Areum Han soo Jeong Lim Sung young Heo Min Ju Lee Sang Hee Park Jae Sung LEE(摄影) Tak Hyun Kim(摄影) 范嘉苑(编译) 不详

位于首尔的圣水洞(Seongsu-dong)绝对是韩国近年最火的热门地区之一。从前,圣水洞到处都是制造商店,包括印刷店、手工鞋店及皮革行业。如今,却吸引了很多MZ世代的年轻人前去,因为圣水洞与其他地方不同,它将过去与现在和谐结合,形成了独... 详细信息

位于首尔的圣水洞(Seongsu-dong)绝对是韩国近年最火的热门地区之一。从前,圣水洞到处都是制造商店,包括印刷店、手工鞋店及皮革行业。如今,却吸引了很多MZ世代的年轻人前去,因为圣水洞与其他地方不同,它将过去与现在和谐结合,形成了独树一帜的文化。这里汇集了各种各样的商业空间,既有由旧工厂和仓库改造的商店,又有融合该地区特色的新生空间,使之拥有了与众不同的独特氛围,许多国际知名品牌也在此开设旗舰店,无疑成为拥有众多时尚品牌的热门区域。

关键词：皮革行业商业空间国际知名品牌仓库改造时尚品牌旗舰店首尔过去与现在

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不讨好的经济政策

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东方企业家 2007年第8期 110-110页

作者： KIM young-soo 张芸（译）

一项经济政策可能带来出乎意料的不良副作用，这种副作用远大于这项政策带来的好处。

关键词：经济政策抑制房价上涨政策政府错误决策副作用人民群众

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当归的等级化研究

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天津中医药 2009年第1期26卷 81-83页

作者：徐荣培庐盛洙李勳揆大田大学本草教研室大邱韩医本草学教室大田大学

中草药标准化是非常有必要的,需要用物理和化学的方法来建立标准。标准化的分级是每位草药生产的指标之一。中国当归的等级分为5级:大体、形状、颜色、香味及杂质是否存在。而韩国的生当归分为三级,分别是60g以上,20～60g之间,20g以下... 详细信息

中草药标准化是非常有必要的,需要用物理和化学的方法来建立标准。标准化的分级是每位草药生产的指标之一。中国当归的等级分为5级:大体、形状、颜色、香味及杂质是否存在。而韩国的生当归分为三级,分别是60g以上,20～60g之间,20g以下。当归身的重量约占整个当归的30%,其表面颜色是浅黄棕色到褐色。一般没有次品。若有次品,多为腐烂、中空、表面色黑或中节呈褐色。提出了当归标准化的等级,并期待着进一步研究。此研究可以做为中药标准化研究的参考指标。

关键词：当归等级化研究

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Wireless,multimodal sensors for continuous measurement of pressure,temperature,and hydration of patients in wheelchair

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npj Flexible Electronics 2023年第1期7卷 479-493页

作者： Seokjoo Cho Hyeonseok Han Hyunwoo Park Sung-Uk Lee Jae-Hwan Kim Sung Woo Jeon Mengqiu Wang Raudel Avila Zhaoqian Xi Kabseok Ko Minsu Park Jungyup Lee Myungwoo Choi Je-Sang Lee Weon Gi Min Byeong-Ju Lee Soyeong Lee Jungrak Choi Jimin Gu Jaeho Park Min Seong Kim Junseong Ahn Osman Gul Chankyu Han Gihun Lee Seunghwan Kim Kyuyoung Kim Jeonghyun Kim Chang-Mo Kang Jahyun Koo Sung soo Kwak Sungbong Kim Dong Yun Choi Seokwoo Jeon Hyung Jin Sung Yong Bae Park Minkyu Je young Tae Cho Yong Suk Oh Inkyu Park Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Advanced 3D Printing Technology Development Division Korea Atomic Energy Research InstituteDaejeon 34057Republic of Korea Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsDalian University of TechnologyDalian 116023P.R.China Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA DUT-BSU Joint Institute Dalian University of TechnologyDalian 116023China Ningbo Institute of Dalian University of Technology Ningbo 315016China Department of Electronics Engineering Kangwon National UniversityChuncheon 24341Republic of Korea Querrey-Simpson Institute for Bioelectronics Northwestern UniversityEvanstonIL 60208USA Sibel Health Inc NilesIL 60714USA Department of Materials Science and Engineering KAIST Institute for The Nanocentury(KINC)Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Rehabilitation Medicine Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of planning and development Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of rehabilitation medicine Pusan national university hospitalBusan 49241Republic of Korea Department of AI Convergence Network Ajou UniversitySuwon 16499Republic of Korea Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897Republic of Korea Korea Photonics Technology Institute Gwangju 61007Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02841Republic of Korea Interdisciplinary Program in Precision Public Health Korea UniversitySeoul 02841Republic of Korea Center

Individuals who are unable to walk independently spend most of the day in a *** population is at high risk for developing pressure injuries caused by ***,early diagnosis and prevention of these injuries still remain ***,we introduce battery-free,wireless,multimodal sensors and a movable system for continuous measurement of pressure,temperature,and hydration at skin *** device design includes a crack-activated pressure sensor with nanoscale encapsulations for enhanced sensitivity,a temperature sensor for measuring skin temperature,and a galvanic skin response sensor for measuring skin hydration *** movable system enables power harvesting,and data communication to multiple wireless devices mounted at skin-cushion interfaces of wheelchair users over full body *** evaluations and numerical simulations of the devices,together with clinical trials for wheelchair patients,demonstrate the feasibility and stability of the sensor system for preventing pressure injuries caused by sitting.

关键词： injuries modal mounted

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Erratum to: Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots

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Nano Research 2021年第3期14卷 895-895页

作者： Xuan-Hung Pham Eunil Hahm Tae Han Kim Hyung-Mo Kim Sang Hun Lee SangChul Lee Homan Kang Ho-young Lee Dae Hong Jeong Hak soo Choi Bong-Hyun Jun Department of Bioscience and Biotechnology Konkuk UniversitySeoul143-701Republic of Korea Department of Urology Seoul National University Bundang HospitalSeongnam13620Republic of Korea Gordon Center for Medical Imaging Department of RadiologyMassachusetts General Hospital and Harvard Medical SchoolBostonMA02114USA Department of Chemistry Education Seoul National UniversitySeoul151-742Republic of Korea

Erratum to Nano Research 2020,13(12):3338-3346 htts://***/00.1007/s12274-020-3014-3 One author name and corresponding affiliation of the original version of this article were unfortunately mislabeled.

关键词： SERS bimetallic

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小前胡中香豆素类成分研究

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天然产物研究与开发 2006年第1期18卷 7-10页

作者：金京玉刘向前陆昌洙朴相勇韩国庆熙大学药学系中南大学化学化工学院制药工程系长沙410083

本文对韩国植物新种小前胡(Angelica czernaeviaKita forma dentate Yook)的根部进行了化学成分研究,从中得到了7个香豆素类化合物,利用波谱方法分别鉴定为异欧前胡素(1),川白芷内酯(2),紫花前胡素(3),7-羟基香豆素(4),紫花前胡醇(5),... 详细信息

本文对韩国植物新种小前胡(Angelica czernaeviaKita forma dentate Yook)的根部进行了化学成分研究,从中得到了7个香豆素类化合物,利用波谱方法分别鉴定为异欧前胡素(1),川白芷内酯(2),紫花前胡素(3),7-羟基香豆素(4),紫花前胡醇(5),紫花前胡苷元(6)和紫花前胡苷(7);同时采用高效液相色谱法对该植物的根、茎、叶和果实进行了主成分川白芷内酯(2)和紫花前胡素(3)定量分析。

关键词：伞形科小前胡香豆素高效液相色谱法主成分定量分析

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WARM NEEDLING FOR OSTEOARTHRITIS: A SYSTEMATIC REVIEW AND METAANALYSIS

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 69-69页

作者： Tae-young Choi Ji Hee Jun Nicola Robinson Ian Appleyard Myeong soo Lee Medical Research Division Korea Institute of Oriental Medicine Allied Health Sciences London South Bank University

The purpose of this systematic review was to evaluate the effectiveness of warm needle treatment of *** databases were searched from their inception through April *** clinical trials(RCTs)were included if a warm needle was used either as the sole treatment or as a part of a combination therapy for *** of bias was assessed according to the Cochrane *** the articles that were identified

关键词： A SYSTEMATIC REVIEW AND METAANALYSIS WARM NEEDLING FOR OSTEOARTHRITIS

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Friction stir butt welding of A5052-O aluminum alloy plates

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中国有色金属学会会刊：英文版 2012年第S3期22卷 619-623页

作者： Sung-Ook YOON Myoung-soo KANG Hyun-Bin NAM Yong-Jai KWON Sung-Tae HONG Jin-Chun KIM Kwang-Hak LEE Chang-Yong LIM Jong-Dock SEO School of Materials Science and Engineering University of Ulsan School of Mechanical Engineering University of Ulsan Technical Research Laboratories Shin Young Co.Ltd.

Friction stir butt welding (FSW) between A5052-O aluminum alloy plates with a thickness of 2 mm was *** rotation speeds of the welding tool were 2000 and 3000 r/min,*** traverse speed was ranged from 100 mm/min to 900 mm/*** defect-free welds with the very smooth surface morphology were successfully obtained,except for at the welding condition of 3000 r/min and 100 mm/*** onion ring structure was observed in the friction-stir-welded zone (SZ) at the condition of 2000 r/min and 100 mm/*** all the welding conditions,the grain size of the SZ was smaller than that of the base metal,and was decreased with the decrease of the tool rotation speed and with the increase of the tool traverse *** stir zone exhibited higher average hardness than the base *** decrease of the tool rotation speed and the increase of the tool traverse speed resulted in the increase in the average hardness of the *** tensile strength of the FSWed plates was similar to that of the base metal,except for at the welding condition of 3000 r/min and 100 mm/*** total elongation of the FSWed plates was lower than that of the base metal.

关键词： friction stir butter welding A5052-O aluminum alloy microstructure mechanical property

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