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Applying Anomaly-based Weather Analysis to the Prediction of Low Visibility Associated with the Coastal Fog at Ningbo-Zhoushan Port in East China

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Advances in Atmospheric Sciences 2019年第10期36卷 1060-1077页

作者： Weihong QIAN Jeremy Cheuk-Hin LEUNG youli chen Siyuan HUANG Department of Atmospheric and Oceanic Sciences School of Physics Peking University Beijing 100871 China Ningbo Meteorological Observatory Ningbo 315012 China Ningbo Meteorological Network and Equipment Support Center Ningbo 315012 China Laboratory of Straits Meteorology Xiamen Meteorological Bureau Xiamen 361013 China

Low visibility episodes (visibility < 1000 m) were studied by applying the anomaly-based weather analysis method. A regional episode of low visibility associated with a coastal fog that occurred from 27 to 28 January 2016 over Ningbo- Zhoushan Port, Zhejiang Province, East China, was first examined. Some basic features from the anomalous weather analysis for this case were identified:(1) the process of low visibility mainly caused by coastal fog was a direct response to anomalous temperature inversion in the lower troposphere, with a warm center around the 925 hPa level, which was formed by a positive geopotential height (GPH) anomaly in the upper troposphere and a negative GPH anomaly near the surface;(2) the positive humidity anomaly was conducive to the formation of coastal fog and rain;(3) regional coastal fog formed at the moment when the southwesterly wind anomalies transferred to northeasterly wind anomalies. Other cases confirmed that the low visibility associated with coastal fog depends upon low-level inversion, a positive humidity anomaly, and a change of wind anomalies from southwesterly to northeasterly, rain and stratus cloud amount. The correlation coefficients of six-hourly inversion, 850?925-hPa-averaged temperature, GPH and humidity anomalies against visibility are ?0.31, 0.40 and ?0.48, respectively, reaching the 99% confidence level in the first half-years of 2015 and 2016. By applying the anomaly-based weather analysis method to medium-range model output products, such as ensemble prediction systems, the anomalous temperature?pressure pattern and humidity?wind pattern can be used to predict the process of low visibility associated with coastal fog at several days in advance.

关键词： traditional synoptic analysis anomaly-based weather analysis low visibility coastal fog

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创伤弧菌坏死性筋膜炎的研究进展

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临床皮肤科杂志 2024年第8期53卷 507-510页

作者：陈幼丽魏思灿李才辉黄玲林小云林天来福建医科大学附属泉州第一医院重症医学科福建泉州362000

创伤弧菌感染引起的坏死性筋膜炎,常在数天内引起败血症和多器官功能衰竭。由于缺乏特异性临床表现及辅助检查,难以早期诊断,常导致错过最佳清创时机,死亡率高。该文对创伤弧菌坏死性筋膜炎的流行病学、感染途径、危险因素、临床表现、... 详细信息

创伤弧菌感染引起的坏死性筋膜炎,常在数天内引起败血症和多器官功能衰竭。由于缺乏特异性临床表现及辅助检查,难以早期诊断,常导致错过最佳清创时机,死亡率高。该文对创伤弧菌坏死性筋膜炎的流行病学、感染途径、危险因素、临床表现、辅助检查及治疗方法、预防方法进行总结,表明早期疑诊此病并立即行清创术是治疗的最关键措施,以期为创伤弧菌坏死性筋膜炎的防治工作提供借鉴。

关键词：弧菌,创伤筋膜炎,坏死性清创术

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两种3D打印导板在下颌角成形术中的适应证及应用效果研究

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华中科技大学学报（医学版） 2024年第4期53卷 494-500页

作者：陈友利安鹏周绍良唐正龙高琼宋具昆杨芷姗王冬香付玉娟王宇贵州医科大学附属口腔医院口腔颌面外科贵阳550001 贵州医科大学口腔医学院贵阳550001 深圳国际旅行卫生保健中心深圳518001

目的分析不同数字化设计及3D打印导板在下颌角成形术中的应用效果。方法选取贵州医科大学附属口腔医院2022年1月至2023年1月收治的12例下颌角肥大患者作为研究对象。所有患者术前均行颅面部CT扫描用于三维模型重建,参考面部协调性及美... 详细信息

目的分析不同数字化设计及3D打印导板在下颌角成形术中的应用效果。方法选取贵州医科大学附属口腔医院2022年1月至2023年1月收治的12例下颌角肥大患者作为研究对象。所有患者术前均行颅面部CT扫描用于三维模型重建,参考面部协调性及美观需求设计个性化下颌角截骨范围。所有患者均以下颌骨保留部分设计升支固定式截骨导板,以下颌角截除部分设计下颌下缘固定式截骨导板,术中根据不同3D打印导板使用情况分为升支固定组(组1)及下颌下缘固定组(组2)。比较两组患者术前术后下颌角形态变化。术后2周行颅面部CT扫描,重叠配准患者虚拟手术设计与手术后颅面部CT数据,测量手术设计与术后下颌角的偏差。结果所有患者均顺利完成下颌角截骨成形手术,患者对术后面型满意。组1患者术前下颌角均为外展型,组2患者中1例下颌角为外展型,其余患者下颌角为内卷型。所有患者术后下颌角角度显著高于术前(P0.05)。两组患者手术设计与术后下颌下缘之间前部、中部、后部偏差水平对比差异无统计学意义(均P>0.05)。结论数字化设计及3D打印导板引导下颌角截骨成形术具有较高的精确性,可获得良好的美容效果;升支固定式截骨导板适用于下颌角外展型患者,下颌下缘固定式截骨导板更适合下颌角内卷型患者。

关键词：下颌角成形术数字化设计手术导板 3D打印技术

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8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury

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Neural Regeneration Research 2013年第2期8卷 133-142页

作者： Zhenli Mao Zhenquan Song Gang Li Wei Lv Xu Zhao Bin Li Xinli Feng youli chen Department of Neurosurgery General Hospital of Shenyang Military Region Postgraduate School Liaoning Medical University Jilin Brain Hospital

Previous studies have reported a neuroprotective effect of 8-hydroxy-2-（di-n-propylamino）tetralin （8-OH-DPAT） against traumatic brain injury. In accordance with the Marmarou method, rat models of diffuse axonal injury were established. 8-OH-DPAT was intraperitoneally injected into model rats. 8-OH-DPAT treated rats maintained at constant temperature served as normal temperature controls TUNEL results revealed that neural cell swelling, brain tissue necrosis and cell apoptosis occurred around the injured tissue. Moreover, the number of Bax-, Bcl-2- and caspase-3-positive cells increased at 6 hours after diffuse axonal injury, and peaked at 24 hours. However, brain injury was attenuated, the number of apoptotic cells reduced, Bax and caspase-3 expression decreased, and Bcl-2 expression increased at 6, 12, 24, 72 and 168 hours after diffuse axonal injury in normal temperature control and in 8-OH-DPAT-intervention rats. The difference was most significant at 24 hours. All indices in 8-OH-DPAT-intervention rats were better than those in the constant temperature group. These results suggest that 8-OH-DPAT inhibits Bax and caspase-3 expression, increases Bcl-2 expression, and reduces neural cell apoptosis, resulting in neuroprotection against diffuse axonal injury. This effect is associated with a decrease in brain temperature.

关键词： neural regeneration brain injury 8-hydroxy-2-(di-n-propylamino)tetralin diffuse axonal injury mildhypothermia cell apoptosis Bcl-2 Bax caspase-3 neuroprotection grant-supported paper photographs-containing paper neuroregeneration

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Expression of angiogenic factors in cerebral arteriovenous malformations

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Neural Regeneration Research 2007年第3期2卷 138-141页

作者： Mingguang Zhao youli chen Zhenquan Song Yongzhong Gao Peiyu Pu Xuezhong Wei Department of Neurosurgery General Hospital of Shenyang Military Area Command of Chinese PLA Shenyang 110016 Liaoning Province China Department of Neurosurgery General Hospital of Tianjin Medical University Tianjin 300052 China

BACKGROUND： In the process of vascularization, vascular endothelial growth factor （VEGF）, angiopoietin-2 and Tie2 are involved in the migration, differentiation and proliferation of vascular endothelial cells, and stimulate the rapid angiogenesis; Tiel and angiopoietin-1 play important roles in facilitating the formation of vascular lumen and maintaining the integrity of vascular wall. Thus the distributions and expressions may be associated with the occurrence of cerebral arteriovenous malformation. OBJECTIVE： To observe the biological effects of angiogenic factors in the occurrence and development of cerebral arteriovenous malformation. DESIGN： An observational comparative experiment. SETTINGS： Department of Neurosurgery, General Hospital of Shenyang Military Area Command of Chinese PLA; Department of Neurosurgery, General Hospital of Tianjin Medical University. PARTICIPANTS： Fresh samples of complete cerebral arteriovenous malformations resected in 47 patients were collected from the Department of Neurosurgery, General Hospital of Tianjin Medical University from August 1999 to May 2001, including 22 males and 25 females, the mean age was 34.5 years. Informed consents were obtained from all the patients or their relatives. The initial symptom was hemorrhage in 28 cases. All the patients were classified according to the clinical imaging data and Spetzler-Martin grading standard, including 11 cases of grade Ⅰ, 17 cases of grade Ⅱ, 11 cases of grade Ⅲ, and 8 cases of grade Ⅳ - Ⅴ. Normal brain tissues resected by decompression due to trauma were taken from 8 patients as controls, including 5 males and 3 females, aging 12 - 65 years. METHODS： ① The expressions of VEGF, Tie receptors, angiopoietin-1, angiopoietin-2, proto-oncogene c-myc and proliferating cell nuclear antigen（PCNA） in the samples of cerebral arteriovenous malformation were detected with immunohistochemical method. Under light microscope, the positively stained rat-anti-human factor Ⅷ-related antigens （sp

关键词： cerebral arteriovenous malformations angiogenesis factor proto-oncogenes proliferating cell nuclear antigen

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化风丹药母中3种优势微生物的实时荧光定量PCR方法的建立

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亚太传统医药 2024年第6期20卷 28-32页

作者：袁小凤舒淇琳曹国琼徐剑陈有丽张永萍贵州中医药大学药学院贵州贵阳550025 国家苗药工程技术研究中心贵州贵阳550025 贵州中药炮制与制剂工程技术研究中心贵州贵阳550025 遵义廖元和堂药业有限公司贵州遵义563000

目的:建立化风丹药母中3种优势微生物米曲霉(Aspergillus oryzae)、汉逊德巴利酵母菌(Debaryomyces hansenii)、阿氏芽孢杆菌(Bacillus aryabhattai)快速、有效的实时荧光定量PCR检测方法。方法:以米曲霉、汉逊德巴利酵母菌、阿氏芽孢... 详细信息

目的:建立化风丹药母中3种优势微生物米曲霉(Aspergillus oryzae)、汉逊德巴利酵母菌(Debaryomyces hansenii)、阿氏芽孢杆菌(Bacillus aryabhattai)快速、有效的实时荧光定量PCR检测方法。方法:以米曲霉、汉逊德巴利酵母菌、阿氏芽孢杆菌的重组质粒为标准质粒,设计特异性引物并进行特异性、灵敏性及重复性实验。结果:3种优势微生物的熔解曲线不在同一峰值。米曲霉、汉逊德巴利酵母菌、阿氏芽孢杆菌的荧光定量PCR最低检测限度分别为0.256、514、5.08 copies/μL。不同质量浓度的标准质粒变异系数(CV)均小于5%。结论:研究表明以荧光定量PCR技术建立的米曲霉、汉逊德巴利酵母菌、阿氏芽孢杆菌的检测方法具有重复性好、特异性强、灵敏度高等优点,可用于化风丹药母发酵过程中微生物的检测及定量。

关键词：化风丹药母米曲霉汉逊德巴利酵母菌阿氏芽孢杆菌实时荧光定量PCR

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纤维素纳米晶对聚酯发泡及力学性能的影响

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工程塑料应用 2014年第3期42卷 104-108页

作者：陈佑立武汉理工大学化学工程学院武汉430070

从棉短绒中提取的纤维素纳米晶(CNs)对聚丁二酸丁二酯(PBS)进行改性,研究了CNs对PBS/CNs复合材料发泡性能和力学性能的影响。结果表明,CNs在PBS材料发泡过程中具有成核剂的作用,当CNs的质量分数为5%时,PBS/CNs复合发泡材料泡孔密度增加... 详细信息

从棉短绒中提取的纤维素纳米晶(CNs)对聚丁二酸丁二酯(PBS)进行改性,研究了CNs对PBS/CNs复合材料发泡性能和力学性能的影响。结果表明,CNs在PBS材料发泡过程中具有成核剂的作用,当CNs的质量分数为5%时,PBS/CNs复合发泡材料泡孔密度增加至9.6×105个/cm3,泡孔直径降低为131μm。PBS/CNs复合发泡材料弯曲强度由5.8 MPa升至6.4 MPa,弯曲弹性模量由221 MPa上升至306 MPa。

关键词：聚丁二酸丁二酯纤维素纳米晶发泡材料

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基于深度Q学习的含用户侧储能微电网频率-电压数字化智能控制策略

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中国电力 2022年第12期55卷 43-50页

作者：林日晖陈友立国网福建省电力有限公司福建福州350003

频率与电压是衡量电能指标的重要标准。针对微电网受到负荷波动而引起的频率/电压调控问题,提出基于深度Q学习(deep Q-learning,DQN)的含用户侧储能微电网智能监控-控制策略。首先,通过考虑用户行为的随机性,增加了用户侧储能输出的随... 详细信息

频率与电压是衡量电能指标的重要标准。针对微电网受到负荷波动而引起的频率/电压调控问题,提出基于深度Q学习(deep Q-learning,DQN)的含用户侧储能微电网智能监控-控制策略。首先,通过考虑用户行为的随机性,增加了用户侧储能输出的随机约束,并引入四象限充放电的模型,构建用户侧储能的集群充放电模型,从而搭建出微电网频率-电压的协同控制模型。其次,设计基于DQN的频率/电压控制器结构与数字化智能控制平台,以系统实时的频率偏差、电压偏差与用户侧储能输出功率的上、下限约束为状态空间,以系统各机组出力为动作空间,并基于频率及电压2个控制目标,完成包含2个本地奖励的全局奖励函数的设计。算例结果表明:与传统PID控制器相比,所提DQN控制器能同时满足频率与电压的控制需求,更有效地应对负荷波动所引起的电能质量问题。

关键词：孤岛微电网用户侧储能频率/电压协调控制深度Q学习算法数字化平台

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Retinol is involved in the intestinal regeneration and strengthens the intestinal barrier during refeeding in broiler chickens

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Journal of Integrative Agriculture 2024年第11期23卷 3843-3859页

作者： youli Wang Huajin Zhou Jing chen Yuqin Wu Yuming Guo Bo Wang Jianmin Yuan Key Laboratory of Qinghai Tibetan Plateau Animal Genetic Resource Reservation and Utilization Ministry of Education/Key Laboratory of Sichuan Province for Qinghai Tibetan Plateau Animal Genetic Resource Reservation and Exploitation College of Animal Science and Veterinary Medicine Southwest Minzu University State Key Laboratory of Animal Nutrition College of Animal Science and Technology China Agricultural University Sichuan New Hope Liuhe Technology Innovation Co.Ltd.

Fasting is typically used before feeding metabolizable energy assessment in broilers. Previous studies have shown that fasting cause atrophy of the intestinal villus. Whether fasting affects intestinal permeability during refeeding by altering barrier function and nutrient absorption is of concern. Here, 23-d-old broilers were randomly assigned to 5 treatments, fasted for 0, 12, 24, 36, and 48 h, respectively, and then refed for 2 d, to study the impact of different duration of fasting on the intestinal regeneration and barrier function during refeeding. Results showed that the intestinal morphology in fasted birds was recovered in 2 d of refeeding at most. As fasting durations increased,enterocytes per intestinal villus were linearly and quadratically increased(both P<0.05), whereas goblet cells per intestinal villus was linearly decreased(both P<0.05). Besides, the mRNA level of lysozyme was linearly decreased as fasting durations increased during refeeding(both P<0.05), while quadratically increased mucin 2 was observed only after 1 d of refeeding(P<0.05). Linear increase effects were observed for claudin 2 and zonula occludens-1with increased fasting durations after 1 d of refeeding(all P<0.05), and linear and quadratical effects were observed for claudin 2 at 2 d of refeeding(both P<0.05). Besides, we found that intestinal permeability to creatinine, 4 and 70 kD dextran were linearly and quadratically decreased with increased fasting durations at 6 h and 1 d of refeeding(all P<0.05). Furthermore, jejunum proteomic from birds refed for 6 h showed that birds fasted for 36 h showed increased antimicrobial peptides and upregulated retinol metabolism when compared to the nonfasted birds(P<0.05).Further study showed that retinyl ester catabolism was inhibited during fasting and enhanced during *** of intestinal organoid culture showed that retinol benefits the cell proliferation and enterocyte *** conclusion, the intestinal permeability t

关键词： broiler chicken fasting intestinal barrier intestinal permeability retinol

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“双高计划”建设项目特征与遴选机制分析

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中国高教研究 2020年第2期 103-108页

作者：陈友力叶赋桂清华大学教育研究院北京100084 重庆工业职业技术学院发展规划与质量保障处重庆401120

中国特色高水平高职学校和专业建设计划是继国家示范性(骨干)高等职业院校建设项目以来中国高等职业教育的又一重要战略部署。通过全面收集和分析197所"双高计划"建设单位的数据,发现"双高计划"建设项目遴选的学校分布、结构特征和地域... 详细信息

中国特色高水平高职学校和专业建设计划是继国家示范性(骨干)高等职业院校建设项目以来中国高等职业教育的又一重要战略部署。通过全面收集和分析197所"双高计划"建设单位的数据,发现"双高计划"建设项目遴选的学校分布、结构特征和地域特征基本达到政策预期效果,但在国家示范(骨干)校与非国家示范(骨干)校、省域和区域之间也存在入选分布不均衡的现象。进一步通过项目制的视角和理论进行阐释,发现"双高计划"具有突出效率优先兼顾公平发展,加强动态调适与保持政策衔接,坚持专业群基础与注重综合实力等三大特征。

关键词： “双高计划” 项目遴选职业教育项目制

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