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Rice science 2008年第2期15卷 153-156页

作者： huANG Ting-you WANG zhi hu Yun-gao SHI Shou-pei PENG Tao Chu Xu-dong SHI Jun XIANG Zu-fen LIU Ding-you Mianyang Agricultural Science Research Institute Mianyang 621023 China

To understand the genetic characteristics of a new photoperiod-sensitive genic male sterile line Mian 9S, some reciprocal crosses were made between Mian 9S and six indica rice materials, Yangdao 6, Luhui 602, Shuihui 527, Mianhui 725, Fuhui 838 and Yixiang 1B. Genetic analysis results suggested that the photoperiod-sensitive genic male sterility （PGMS） of Mian 9S was controlled by a single recessive nuclear gene. Thus, the F2 population derived from the cross of Yangdao 6/Mian 9S was used to map the PGMS gene in Mian 9S. By using SSR markers, the PGMS gene of Mian 9S was mapped on one side of the markers, RM6659 and RM1305, on rice chromosome 4, with the genetic distances of 3.0 cM and 3.5 cM, respectively. The gene was a novel PGMS gene and designated tentatively as pms4. In addition, the application of the pms4 gene was discussed.

关键词： genetic analysis gene mapping photoperiod-sensitive genic male sterility rice (Oryza sativa)

Repetitive transcranial magnetic stimulation in Alzheimer’s disease:effects on neural and synaptic rehabilitation

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Neural Regeneration Research 2025年第2期20卷 326-342页

作者： Yi Ji Chaoyi Yang Xuerui Pang Yibing Yan Yue Wu zhi Geng Wenjie hu Panpan hu Xingqi Wu Kai Wang Department of Neurology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders HefeiAnhui ProvinceChina Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health HefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina Department of Psychology and Sleep Medicine The Second Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina

Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and *** Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neurodegeneration and ultimately disrupting the operational abilities in daily life,leaving patients *** transcranial magnetic stimulation is a cost-effective,neuro-modulatory technique used for multiple neurological *** the past two decades,it has been widely used to predict cognitive decline;identify pathophysiological markers;promote neuroplasticity;and assess brain excitability,plasticity,and *** has also been applied to patients with dementia,because it can yield facilitatory effects on cognition and promote brain recovery after a neurological ***,its therapeutic effectiveness at the molecular and synaptic levels has not been elucidated because of a limited number of *** study aimed to characterize the neurobiological changes following repetitive transcranial magnetic stimulation treatment,evaluate its effects on synaptic plasticity,and identify the associated *** review essentially focuses on changes in the pathology,amyloidogenesis,and clearance pathways,given that amyloid deposition is a major hypothesis in the pathogenesis of Alzheimer’s *** mechanisms associated with repetitive transcranial magnetic stimulation procedures and different pathways mediating gene transcription,which are closely related to the neural regeneration process,are also ***,we discuss the outcomes of animal studies in which neuroplasticity is modulated and assessed at the structural and functional levels by using repetitive transcranial magnetic stimulation,with the aim to highlight future directions for better clinical translations.

关键词： Alzheimer’s disease amyloid deposition apoptotic mechanisms biomarker neural regeneration neurodegeneration repetitive transcranial magnetic stimulation synaptic plasticity

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米茶的消化特性研究

现代食品科技 2017年第3期33卷 88-92,46页

作者：熊礼橙赵思明牛猛刘友明胡志全华中农业大学食品科技学院湖北武汉430070

以大米为原料,经浸润和焙炒等工序制得米茶。分别采用胰酶-糖化酶和胃蛋白酶-胰蛋白酶模拟淀粉和蛋白质在人体中的消化进程,研究动植物油脂、焙炒时间和焙炒温度对米茶淀粉和蛋白消化特性的影响,为米茶的加工提供基础数据。焙炒工艺会... 详细信息

以大米为原料,经浸润和焙炒等工序制得米茶。分别采用胰酶-糖化酶和胃蛋白酶-胰蛋白酶模拟淀粉和蛋白质在人体中的消化进程,研究动植物油脂、焙炒时间和焙炒温度对米茶淀粉和蛋白消化特性的影响,为米茶的加工提供基础数据。焙炒工艺会影响米茶的消化特性;焙炒可抑制米茶中淀粉的消化过程,有利于血糖指数的降低;添加油脂对米茶的消化有明显的抑制作用,对米茶消化液中葡萄糖含量有显著下降作用,但油脂的种类对淀粉的消化率抑制影响不大;过高的焙炒温度(200℃以上)和时间(35 min以上)会使米茶蛋白质的消化性能降低;焙炒对米茶消化后的绝对氨基酸含量基本无影响,焙炒会降低米茶酶解消化后游离赖氨酸和苏氨酸的含量,但适宜的焙炒条件对必需氨基酸的含量影响不大。

关键词：米茶焙炒淀粉蛋白质消化特性

A facile approach to construct hybrid multi-shell calcium phosphate gene particles

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第4期11卷 292-297页

作者： zhi-xue XU Ran ZHANG you-xiang WANG Qiao-ling hu MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering Zhejiang University Hangzhou 31002 7 China

The calcium phosphate (CaP) particles have attracted much attention in gene therapy. How to construct stable gene particles was the determining factor. In this study,hybrid multi-shell CaP gene particles were successfully constructed. First,CaP nanoparticles served as a core and were coated with DNA for colloidal stabilization. The ξ-potential of DNA-coated CaP nanoparticles was -15 mV. Then polyethylenimine (PEI) was added and adsorbed outside of the DNA layer due to the electrostatic attraction. The ξ-potential of hybrid multi-shell CaP particles was slightly positive. With addition of PEI,the hybrid multi-shell particles could condense DNA effectively,which was de-termined by ethidium bromide (EtBr) exclusion assay. The hybrid particles were spherical and uniform with diameters of about 150 nm at proper conditions. By simple modification of PEI,the hybrid multi-shell CaP gene particles were successfully constructed. They may have great potential in gene therapy.

关键词： Calcium phosphate Polyethylenimine (PEI) Hybrid Gene

‘博采’(F_1)番茄杂种优势的早期生理预测研究

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江汉大学学报（自然科学版） 2003年第4期31卷 69-72页

作者：陈禅友胡志辉周利琳潘磊江汉大学医学与生命科学学院湖北武汉430056

观测了新育成番茄组合‘博采’F1代及其亲本种子活力等生理指标,并以此作杂种优势的早期预测,同时研究了种子萌发过程中吸水量和呼吸速率的动态变化.结果表明:‘博采’F1代在室内的简化活力指数和活力指数等重要指标有明显超亲优势,而反... 详细信息

观测了新育成番茄组合‘博采’F1代及其亲本种子活力等生理指标,并以此作杂种优势的早期预测,同时研究了种子萌发过程中吸水量和呼吸速率的动态变化.结果表明:‘博采’F1代在室内的简化活力指数和活力指数等重要指标有明显超亲优势,而反交 F1代 (JD02×JD01) 杂种优势不明显,此结果与田间生产性能表现一致,故运用种子活力测定可作番茄杂种优势的早期预测.在采种和贮藏条件一致的条件下种子活力差异主要反映了基因型的差异,活力优势品种种子吸水较快、呼吸代谢强度较高、种胚生长旺盛.

关键词：番茄杂种优势生理预测种子活力 '博采’F1代

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我国残膜回收装备研发要点及实践

新疆农机化 2016年第5期 8-11页

作者：陈有庆胡志超吴峰顾峰玮徐弘博游兆延施丽莉农业部南京农业机械化研究所江苏南京210000

文中阐述了国内外残膜回收技术设备现状,分析了残膜机械化回收技术难点与研发要点,结合残膜机械化回收技术难点与研发要点介绍了项目组研制的几种残膜回收设备,以供读者参考。

关键词：残膜回收技术装备现状

Analysis of Key Disciplinary Parameters in Floating Offshore Wind Turbines with An AI-Based SADA Method

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China Ocean Engineering 2022年第4期36卷 649-657页

作者： CHEN Peng hu zhi-qiang School of Engineering Newcastle UniversityNewcastle upon TyneNE17RUUnited Kingdom

Floating offshore wind turbines(FOWTs)are a promising offshore renewable energy harvesting facility but requesting multiple-disciplinary analysis for their dynamic performance ***,engineering-fidelity level tools and the empirical parameters pose challenges due to the strong nonlinear coupling effects of FOWTs.A novel method,named SADA,was proposed by Chen and hu(2021)for optimizing the design and dynamic performance prediction of FOWTs in combination with AI *** the SADA method,the concept of Key Disciplinary Parameters(KDPs)is also proposed,and it is of crucial importance in the SADA *** purpose of this paper is to make an in-depth investigation of the characters of KDPs and the internal correlations between different KDPs in the dynamic performance prediction of ***,a brief description of SADA is given,and the basin experimental data are used to conduct the training process of ***,categories and boundary conditions of KDPs are *** types of KDPs are given,and different boundary conditions are used to analyze *** results show that the wind and current in Environmental KDPs are strongly correlated with the percentage difference of dynamic response rather than that by wave *** general,the optimization results of SADA consider the specific basin environment and the coupling results between different KDPs help the designers further understand the factors that have a more significant impact on the FOWTs system in a specific domain.

关键词： floating offshore wind turbine SADA KDPs machine learning basin experiment

Interaction Effects of Gene Polymorphisms and Obesity on Nonalcoholic Fatty Liver Disease

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Biomedical and Environmental Sciences 2019年第10期32卷 793-796页

作者： SUN Xiao Ya HE zhi Qiang WANG Li Qun WANG zhi Zhong BAI Fei hu you Yan Jie Department of Epidemiology and Statistic School of Public Health and ManagementNingxia Medical UniversityYinchuan 750004NingxiaChina Department of gastroenterology at Ningxia hui Autonomous Region People's Hospital Yinchuan 750021NingxiaChina

Nonalcoholic fatty liver disease(NAFLD)is a common chronic condition that affects adults and has a global prevalence of 25%[1],with the prevalence being 31%among the general population in China[2].A meta-analysis of studies conducted over the past few years has reported that the predicting factors for NAFLD include obesity,type 2 diabetes mellitus,lifestyle,and genetic *** risk of developing NAFLD has been reported to be 3.5-fold higher in individuals with obesity than in the general[3].

关键词： NAFLD obesity prevalence

Ethylene Oligomerization Promoted by Nickel Complexeswith 8-Iminoquinoline Derivatives

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Chinese Chemical Letters 2001年第8期12卷 691-692页

作者： Zi Long LI Wen hua SUN zhi MA you Liang hu Chang Xing SHAO State Key Laboratory of Engineering Plastics and The Center for Molecular Sciences Institute of Chemistry The Chinese Academy of SciencesBeijing 100080

A series of 8-iminoquinoline derivatives nickel complexes were synthesized to proceed high activity in ethylene oligomerization.

关键词： Nickel Complex iminoquinoline ethylene oligomerization homogeneous catalysis.

Continuum damage mechanics based modeling progressive failure of woven-fabric composite laminate under low velocity impact

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第3期11卷 151-164页

作者： zhi-gang hu Yan ZHANG State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China Arup Shanghai Shanghai 200031China

A continuum damage mechanics (CDM) meso-model was derived for both intraply and interply progressive failure behaviors of a 2D woven-fabric composite laminate under a transversely low velocity *** in-plane anisotropic damage constitutive model of a 2D woven composite ply was derived based on CDM within a thermodynamic framework,an elastic constitutive model with damage for the fibre directions and an elastic-plastic constitutive model with damage for the shear *** progressive failure behavior of a 2D woven composite ply is determined by the damage internal variables in different directions with appropriate damage evolution *** interface between two adjacent 2D woven composite plies with different ply orientations was modeled by a traction-separation law based interface *** isotropic damage constitutive law with CDM properties was used for the interface element,and a damage surface which combines stress and fracture mechanics failure criteria was employed to derive the damage initiation and evolution for the mixed-mode delamination of the interface *** analysis and experiments were both carried out on a 2D woven glass fibre/epoxy *** simulation results are in agreement with the experimental counterparts,verifying the progressive failure model of a woven composite *** proposed model will enhance the understanding of dynamic deformation and progressive failure behavior of composite laminate structures in the low velocity impact process.

关键词： Continuum damage mechanics (CDM) Woven composite laminate Low velocity impact Interface element Cohesive zone