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Effects of acupuncture in treating insomnia due to spleen-stomach disharmony syndrome and its influence on intestinal microbiome: Study protocol for a randomized controlled trial

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Journal of Integrative Medicine 2019年第3期17卷 161-166页

作者： Ya-ru huangfu Wei Peng Bao-jun Guo Zhi-fu Shen Li Li Shi-wei Liu hui Zheng you-ping hu Acupuncture and Tuina School Chengdu University of Traditional Chinese Medicine

Background: Insomnia is a common complaint that is closely related to gastrointestinal symptoms, which is consistent with the traditional Chinese medicine classical theory of ‘‘stomach disharmony leading to restless sleep." Acupuncture is an effective complementary and alternative medicine therapy to improve gastrointestinal function and restore the normal sleep-wake cycle. However, studies on the effectiveness of acupuncture for insomnia due to spleen-stomach disharmony syndrome are limited to case reports and few randomized controlled trials; deeper research on its mechanism is still lacking. This randomized controlled trial aims to assess the treatment efficacy of ‘‘harmonizing stomach to tranquilize mind"acupuncture for insomnia and its influence on the intestinal ***/design: This is a randomized, single-blind, parallel-group study. Sixty eligible patients with insomnia due to spleen-stomach disharmony syndrome will be randomly divided into two groups(1:1 allocation ratio). The intervention group will use ‘‘harmonizing stomach to tranquilize mind"acupuncture, and the control group will receive sham acupuncture. Participants will receive 5 acupuncture treatment sessions per week for 4 consecutive weeks. The Pittsburgh Sleep Quality Index will be used to evaluate the clinical efficacy of acupuncture treatment by making assessments at baseline, the end of treatment and the end of the follow-up. High-throughput 16 S ribosomal ribonucleic acid gene sequencing will be performed to detect changes in the intestinal microbial composition before and after ***: The results of this trial are expected to confirm that ‘‘harmonizing stomach to tranquilize mind" acupuncture can effectively relieve insomnia and alter the intestinal microbiome.

关键词： Insomnia Gastrointestinal symptoms Acupuncture Intestinal microbiome Randomized controlled trial Study protocol

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乌梅各入药部位脂肪油成分分析比较

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时珍国医国药 2007年第9期18卷 2106-2107页

作者：陈鸿平陈林刘友平胡媛成都中医药大学四川成都610075

目的对乌梅各入药部位的脂肪油成分进行分析比较。方法采用重量法和气相色谱-质谱(GC-MS)联用技术分别测定脂肪油含量和组成。结果乌梅果肉脂肪油含量为1.22%,核壳脂肪油含量为3.15%,种子脂肪油含量为27.73%。从果肉中鉴定了21种脂肪油... 详细信息

目的对乌梅各入药部位的脂肪油成分进行分析比较。方法采用重量法和气相色谱-质谱(GC-MS)联用技术分别测定脂肪油含量和组成。结果乌梅果肉脂肪油含量为1.22%,核壳脂肪油含量为3.15%,种子脂肪油含量为27.73%。从果肉中鉴定了21种脂肪油成分,从核壳中鉴定了15种脂肪油成分,从种子中鉴定了17种脂肪油成分。主要为油酸、亚油酸、软脂酸、10,13-十八碳二烯酸、13-十八碳烯酸等。结论乌梅果肉、核壳和种仁在脂肪油含量、组成成分和相对含量上都有较大差异,为乌梅分部位入药提供了依据。同时证明乌梅脂肪油有进一步开发利用的价值。

关键词：乌梅脂肪油气相色谱-质谱连用技术

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CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPOINT APPLICATION ON HYPERHIDROSIS IN COPD PATIENTS

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Journal of Integrative Medicine 2014年第3期 323-323页

作者： Shuang-shuang Liu Rui-rui Sun you-ping hu Chengdu University of Traditional Chinese Medicine

Objective: To observe the clinical effect of the acupoint application in treating hyperhidrosis in patients with chronic obstructive pulmonary disease(COPD).Methods: Sixty COPD patients were randomized into two groups, including the acupoint application group and the control *** groups remained using the Western medicine as their basic treatment, and the treatment group added acupoint application at bilateral acupoints Feishu(BL13), Pishu(BL20), Shenshu(BL23) and Shenque(CV8).Results: There were 19 cases(63.33%) of patients healed in the treatment group, 5 cases(16.67%) with significant effect, 4 cases(13.33%) with mild effect and 2 cases(6.67%) with no *** total effective rate was 93%, which was superior to the control ***: Acupoint application appears to have obvious effect in treating hyperhidrosis in COPD patients, which may provide a new method for treating this disease.

关键词： COPD CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPOINT APPLICATION ON HYPERHIDROSIS IN COPD PATIENTS

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社交媒体健康信息用户信任形成机理研究

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现代情报 2025年第1期45卷 97-111页

作者：初彦伯王萍胡姝姝吉林大学商学与管理学院吉林长春130012

[目的/意义]在公共卫生事件频发的背景下,国民对健康信息需求急剧增长。社交媒体作为用户信息获取的重要途径之一,在高效传播健康信息的同时,也为虚假健康信息的产生和传播提供便利条件。随着社交媒体渗透力和影响力不断扩大,用户对健... 详细信息

[目的/意义]在公共卫生事件频发的背景下,国民对健康信息需求急剧增长。社交媒体作为用户信息获取的重要途径之一,在高效传播健康信息的同时,也为虚假健康信息的产生和传播提供便利条件。随着社交媒体渗透力和影响力不断扩大,用户对健康信息的不确定感愈发强烈。鉴于此,本文对社交媒体健康信息用户的信任形成机理进行探索,以期为后续相关研究提供参考和借鉴。[方法/过程]解构社交媒体健康信息用户信任形成的要素,建构面向用户感知过程的信任综合框架,从用户、信息和环境3个方面提出社交媒体健康信息用户信任理论假设模型,并对结构模型进行修正。[结果/结论]研究从理论层面明晰社交媒体健康信息用户感知信任过程以及用户心理变化的进程。研究还发现热评情感极性、涉入度、信源可信度、冲突解决对信任存在显著的正向影响。信任对采纳意愿存在显著的正向影响。参照群体规范对采纳意愿存在显著的正向影响。此外,信任分别在热评情感极性、涉入度、信源可信度和冲突解决与信息采纳意愿之间起到完全中介作用。

关键词：社交媒体健康信息信任感知可信度

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Correlation of anaerobic ammonium oxidation and denitrification

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Journal of Environmental Sciences 2006年第2期18卷 227-231页

作者： Zhu Jing-ping hu Yong-you LIANG hui-qiang College of Environmental Science and Engineering South China University of Technology Guangzhou 510640 China College of Environment and Resources Engineering Southwest University Science and Technology Mianyang 621002 China

The feasibility of the nitrous organic wastewater treated was studied in seven anaerobic sequencing batch reactors（ASBRs）（0^#-6^#） which had been run under stable anaerobic ammonium oxidation （Anammox）. By means of monitoring and data analysis of COD, NH4^#-N, NO2^--N, NO3^--N and pH, and of microbial test, the results revealed that the optimal Anammox performance was achieved from 2^# reactor in which COD/NH4^＋ -N was 1.65, Anammox bacteria and denitrification bacteria could coexist, and Anammox reaction and denitrification reaction could occur simultaneously in the reactors. The ratio of NH4^＋-N consumed ： NO2^- -N consumed ： NO3^- -N produced was 1：1.38：0.19 in 0^# reactor which was not added glucose in the wastewater. When different ratio of COD and NH4^＋-N was fed for the reactors, the ratio of NO2^- -N consumed： NH4^＋-N consumed was in the range of 1.51-2.29 and the ratio of NO;-N produced： NH4^＋ -N consumed in the range of 0 -0.05.

关键词： anaerobic ammonium oxidation (Anammox) anaerobic sequencing batch reactor (ASBR) biological denitrification denitrification

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Asymmetric dimethylarginine:A novel biomarker of gastric mucosal injury?

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World Journal of Gastroenterology 2011年第17期17卷 2178-2180页

作者： Zhe Zhang Yi-you Zou Fu-Jun Li Chang-ping hu Department of Pharmacology School of Pharmaceutical Sciences Central South University Changsha 410078 Hunan Province China Department of Digestive Medicine Xiang-Ya Hospital Central South University Changsha 410078 Hunan Province China

Nitric oxide(NO),a multifunctional endogenous gas molecule,is metabolized from L-arginine by enzymatic reaction in the presence of nitric oxide ***,an important gas signaling molecule,is a gastric mucosa protective factor that contributes significantly to maintain normal gastric mucosa *** increases gastric mucosa blood flow,regulates the secretion of mucus and bicarbonate,and inhibits the secretion of gastric *** dimethylarginine(ADMA) has been identified as the major endogenous inhibitor of nitric oxide *** function of ADMA is to decrease NO production via inhibiting nitric oxide synthase *** inhibiting NO synthesis,ADMA also directly induces oxidative stress and cell apoptosis,and participates in inflammation *** systemic accumulation was observed in conjunction with several cardiovascular and metabolic *** also mediates gastric ulcer injury induced by ethanol,stress,helicobacter pylori and *** mechanism of ADMA directly producing adverse effect in gastric mucosa is incompletely *** is widely accepted that NO bioavailability decrease is the majority *** of apoptosis and aggravation of inflammation may be other important mechanisms of ADMA-induced gastric *** might be a novel clinical and experimental biomarker related to gastric mucosa *** therapeutic tool targeting to ADMA is available in multiple cardiovascular diseases,it is unknown in gastrointestinal *** strategy to inhibit ADMA is beneficial to gastric ulcer induced by ethanol in ***,ADMA might be a candidate of therapeutic target in gastric mucosa damage.

关键词： Asymmetric dimethylarginine Mucosal injury Nitric oxide

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Examination on the Optical Absorption and Electron Paramagnetic Resonance Spectra of Cr^(3+) ions in α-LiIO_(3) Crystal

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Chinese Physics Letters 1998年第3期15卷 221-222页

作者： hu ping Institute of Solid State Physics Sichuan Normal UniversityChengdu 610068

The optical and electron paramagnetic resonance spectra of Cr^(3+) ions in the α-LilO_(3) crystal are explained based on the complete diagonalization procedure and a crystal-field-like *** results agree well with exp... 详细信息

关键词： crystal Electron explained

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Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer

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World Journal of Gastroenterology 2014年第20期20卷 6329-6335页

作者： hu Zhang you-Qing Zhu Ya-Qiong Wu ping Zhang Jian Qi Department of Gastroenterology and Clinical Center of Intestinal and Colorectal Diseases of hubei Province Zhongnan Hospital of Wuhan University Department of Gastroenterology Hubei Provincial Corps Hospital Chinese People’s Armed Police Force Department of Dermatology Yijishan Hospital of Wannan Medical College

AIM: To investigate the feasibility of detecting aberrantly hypermethylated Wnt-antagonist gene promoters (SFRP2 and WIF-1) in fecal DNA as non-invasive biomarkers for early colorectal cancer (CRC).

关键词： Colorectal carcinoma Secreted frizzled-related protein 2 Wnt inhibitory factor-1 Stool Methylation

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On the Radius of Analyticity of Solutions to 3D Navier-Stokes System with Initial Data in L^(p)

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Chinese Annals of Mathematics,Series B 2022年第5期43卷 749-772页

作者： Ruilin hu ping ZHANG Academy of Mathematics&Systems Science the Chinese Academy of SciencesBeijing 100190China Academy of Mathematics&Systems Science and hua Loo-Keng Key Laboratory of Mathematics the Chinese Academy of SciencesBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China

Given initial data u0 ∈ L^(p)(R^(3)) for some p in [3,18/5 [,the auhtors first prove that3 D incompressible Navier-Stokes system has a unique solution μ=μL+v with μL=^(def)e^(t△)μ_(0) and ν∈L^(∞)([0,T];H^(5/2)-^(6/p)∩L^(1)([0,T];H^(9/2-6/p) for some positive time *** they derive an explicit lower bound for the radius of space analyticity of v,which in particular extends the corresponding results in [Chemin,J.-Y.,Gallagher,*** Zhang,P.,On the radius of analyticity of solutions to semi-linear parabolic system,***.,27,2020,1631-1643,Herbst,*** Skibsted,E.,Analyticity estimates for the Navier-Stokes equations,*** Math.,228,2011,1990-2033] with initial data in H^(s)(R^(3)) for s ∈ [1/2,3/2[.

关键词： Incompressible Navier-Stokes equations Radius of analyticity Littlewood-Paley theory

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Synthesis, Structure Characterization and Biological Activity of a Novel Amino Acid Salt (HAla)_8(H_30)_(10)[PMo_(12)O_(40)]_6·22H_2O

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Chemical Research in Chinese Universities 2001年第4期17卷 356-361页

作者： HAN Zheng-bo WANG En-bo LUAN Guo-you hu Chang-wen CHANG Ya-ping LI Juan hu Ning-hai JIA Heng-qing Faculty of Chemistry Northeast Normal UniversityChangchun 130024P.R.China College of Medicine Jilin UniversityChangchun 130021P.R.China Changchun Institude of Applied Chemistry Chinese Academy of Sciences.Changchun 130022P.R.China

A novel compound was synthesized and characterized by means of elemental analysis, IR and UV spectra, TG, CV and single crystal X-ray diffraction. The compound crystallized in an orthorhombic space group C222 with a = 1. 622 4(3) nm, b=3. 498 4(7) nm, c=l. 301 5(3) nm,V=7. 387(3) nm3, Z = 6, R1 = 0. 037 3, wR2 = 0. 114 0. The Ala (Ala = alanine) molecules were protonated at the amino nitrogen N (1) and the C (2) of Ala group with the terminal oxygen atom O(15), O(14), O(26) and O(27) of the polyoxometalates participating in the hydrogen bond network. The anti-tumor activity of the title compound was estimated against Hela and Pc-3m cancer cells.

关键词： Polyoxometalate Ala Crystal structure Antitumor activity

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