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A novel matrix topology-based analysis method of thermal circuits for reliability optimization of HSER

Chinese Journal of Aeronautics 2024年第4期37卷 479-492页

作者： Huimin liang Bo LI Jiaxin you Shan JIANG Mengtong ZHU Aobo WANG department of Electrical Engineering Harbin Institute of TechnologyHarbin 150001China Nanjing Research Institute of Electronics Technology Nanjing 210008China

Hermetically Sealed Electromagnetic Relay(HSER), used in aviation and aerospace,demands high reliability due to its critical applications. Given its complex operating conditions, efficient thermal analysis is essential for optimizing reliability. The commonly used Finite Element Method(FEM) is often time-consuming and may not be efficient or adaptable for complex multi-dimensional system calculations and design processes. This paper introduces an analysis method for thermal networks based on matrix perspective technology, encompassing matrix transformation, backpropagation of the heat path model, temperature rise calculation, solution comparison, and product implementation. Using the similarity theory of heat circuits, a basic thermal unit is established. Based on the fundamental connection between key components, a thermal network for a typical HSER is designed. An experimental system is set up, and the thermal network model's accuracy is confirmed using test data. Employing the topology analysis method, the topology of the thermal network is analyzed under both coil-energized and de-energized states. Potential thermal paths are identified, leading to optimized solutions for the HSER. Utilizing these solutions, the thermal path matrix topology model is backpropagated to the thermal path for temperature rise calculations. When compared to prototype HSER test data, the efficiency and accuracy of this matrix topology-based analysis method are confirmed.

关键词： Thermal networks HSER(Hermetically Sealed Electromagnetic Relay) Heat-circuit topology model Heat-circuit matrix Optimization design

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Optimizing prediction models for pancreatic fistula after pancreatectomy:Current status and future perspectives

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World Journal of Gastroenterology 2024年第10期30卷 1329-1345页

作者： Feng Yang John A Windsor de-liang Fu department of Pancreatic Surgery Huashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200040China Surgical and Translational Research Centre Faculty of Medical and Health SciencesUniversity of AucklandAuckland 1142New Zealand

Postoperative pancreatic fistula(POPF)is a frequent complication after pancre-atectomy,leading to increased morbidity and mortality.Optimizing prediction models for POPF has emerged as a critical focus in surgical research.Although over sixty models following pancreaticoduodenectomy,predominantly reliant on a variety of clinical,surgical,and radiological parameters,have been documented,their predictive accuracy remains suboptimal in external validation and across diverse populations.As models after distal pancreatectomy continue to be pro-gressively reported,their external validation is eagerly anticipated.Conversely,POPF prediction after central pancreatectomy is in its nascent stage,warranting urgent need for further development and validation.The potential of machine learning and big data analytics offers promising prospects for enhancing the accuracy of prediction models by incorporating an extensive array of variables and optimizing algorithm performance.Moreover,there is potential for the development of personalized prediction models based on patient-or pancreas-specific factors and postoperative serum or drain fluid biomarkers to improve accuracy in identifying individuals at risk of POPF.In the future,prospective multicenter studies and the integration of novel imaging technologies,such as artificial intelligence-based radiomics,may further refine predictive models.Addressing these issues is anticipated to revolutionize risk stratification,clinical decision-making,and postoperative management in patients undergoing pancre-atectomy.

关键词： Pancreatic fistula Pancreaticoduodenectomy Distal pancreatectomy Central pancreatectomy Prediction model Machine learning Artificial intelligence

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DGS1 improves rice disease resistance by elevating pathogenassociated molecular pattern-triggered immunity

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aBIOTECH 2024年第1期5卷 46-51页

作者： Yu Wang Chuan Zheng you-liang Peng Qian Chen MOA Key Lab of Pest Monitoring and Green Management and Frontiers Science Center for Molecular design Breeding China Agricultural UniversityBeijing 100193China

Rice yield and disease resistance are two crucial factors in determining the suitability of a gene for agricultural breeding.decreased grain size1(DGS1),encoding an RING-type E3 ligase,has been found to have a positive effect on rice yield by regulating rice grain number and 1000-grain weight.However,the role of DGS1 in rice blast resistance is still unknown.In this study,we report that DGS1 enhances disease resistance by improving PTI responses,including stronger ROS burst and MAPK activation,and also increased expression of defense-related genes.Furthermore,DGS1 works in conjunction with ubiquitin conjugating enzyme OsUBC45 as an E2-E3 pair to facilitate the ubiquitin-dependent degradation of OsGSK3 and OsPIP2;1,thereby influencing rice yield and immunity,respectively.Therefore,the DGS1-OsUBC45 module has the potential in facilitating rice agricultural breeding.

关键词： Rice blast PTI ERAD E2-E3 pair Ubiquitination

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Liquefaction susceptibility and deformation characteristics of saturated coral sandy soils subjected to cyclic loadings-a critical review

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 261-296页

作者： Chen Guoxing Qin you Ma Weijia liang Ke Wu Qi C.Hsein Juang Institute of Geotechnical Engineering Nanjing Tech UniversityNanjing 210009China Civil Engineering and Earthquake Disaster Prevention Center of Jiangsu Province Nanjing 210009China School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing 210094China College of Civil Aviation Nanjing University of Aeronautics and AstronauticsNanjing 210016China Glenn department of Civil Engineering Clemson UniversityClemsonSC 29634USA

Coral sandy soils widely exist in coral island reefs and seashores in tropical and subtropical regions.Due to the unique marine depositional environment of coral sandy soils,the engineering characteristics and responses of these soils subjected to monotonic and cyclic loadings have been a subject of intense interest among the geotechnical and earthquake engineering communities.This paper critically reviews the progress of experimental investigations on the undrained behavior of coral sandy soils under monotonic and cyclic loadings over the last three decades.The focus of coverage includes the contractive-dilative behavior,the pattern of excess pore-water pressure(EPWP)generation and the liquefaction mechanism and liquefaction resistance,the small-strain shear modulus and strain-dependent shear modulus and damping,the cyclic softening feature,and the anisotropic characteristics of undrained responses of saturated coral sandy soils.In particular,the advances made in the past decades are reviewed from the following aspects:(1)the characterization of factors that impact the mechanism and patterns of EPWP build-up;(2)the identification of liquefaction triggering in terms of the apparent viscosity and the average flow coefficient;(3)the establishment of the invariable form of strain-based,stress-based,or energy-based EPWP ratio formulas and the unique relationship between the new proxy of liquefaction resistance and the number of cycles required to reach liquefaction;(4)the establishment of the invariable form of the predictive formulas of small strain modulus and strain-dependent shear modulus;and(5)the investigation on the effects of stress-induced anisotropy on liquefaction susceptibility and dynamic deformation characteristics.Insights gained through the critical review of these advances in the past decades offer a perspective for future research to further resolve the fundamental issues concerning the liquefaction mechanism and responses of coral sandy sites subjected to cyclic loadings associated with seismic eve

关键词： liquefaction susceptibility dynamic deformation characteristics coral sandy soil cyclic loading review and prospect

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Unraveling the enigma:A comprehensive review of solid pseudopapillary tumor of the pancreas

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 614-629页

作者： Ye-Cheng Xu de-liang Fu Feng Yang department of Pancreatic Surgery Pancreatic Disease InstituteHuashan HospitalFudan UniversityShanghai 200040China

Solid pseudopapillary tumor of the pancreas(SPTP)is a rare neoplasm predom-inantly observed in young females.Pathologically,CTNNB1 mutations,β-catenin nuclear accumulation,and subsequent Wnt-signaling pathway activation are the leading molecular features.Accurate preoperative diagnosis often relies on imaging techniques and endoscopic biopsies.Surgical resection remains the mainstay treatment.Risk models,such as the Fudan Prognostic Index,show promise as predictive tools for assessing the prognosis of SPTP.Establishing three types of metachronous liver metastasis can be beneficial in tailoring individu-alized treatment and follow-up strategies.despite advancements,challenges persist in understanding its etiology,establishing standardized treatments for unresectable or metastatic diseases,and developing a widely recognized grading system.This comprehensive review aims to elucidate the enigma by consolidating current knowledge on the epidemiology,clinical presentation,pathology,molecular characteristics,diagnostic methods,treatment options,and prognostic factors.

关键词： Pancreas Solid pseudopapillary tumor β-catenin Endoscopic ultrasound Surgery Recurrence Liver metastasis Prognostic prediction

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AstroPose: Astronaut pose estimation using a monocular camera during extravehicular activities

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Science China Technological Sciences 2024年第6期67卷 1933-1945页

作者： LIU ZiBin LI you WANG ChunHui LIU liang GUAN BangLei SHANG Yang YU QiFeng College of Aerospace Science and Engineering National University of Defense Technology Key Laboratory of Human Factors Engineering China Astronaut Research and Training Center

With the completion of the Chinese space station, an increasing number of extravehicular activities will be executed by astronauts,which is regarded as one of the most dangerous activities in human space exploration. To guarantee the safety of astronauts and the successful accomplishment of missions, it is vital to determine the pose of astronauts during extravehicular activities. This article presents a monocular vision-based pose estimation method of astronauts during extravehicular activities, making full use of the available observation resources. First, the camera is calibrated using objects of known structures, such as the spacesuit backpack or the circular handrail outside the space station. Subsequently, the pose estimation is performed utilizing the feature points on the spacesuit. The proposed methods are validated both on synthetic and semi-physical simulation experiments, demonstrating the high precision of the camera calibration and pose estimation. To further evaluate the performance of the methods in real-world scenarios, we utilize image sequences of Shenzhou-13 astronauts during extravehicular activities. The experiments validate that camera calibration and pose estimation can be accomplished solely with the existing observation resources, without requiring additional complicated equipment. The motion parameters of astronauts lay the technological foundation for subsequent applications such as mechanical analysis, task planning, and ground training of astronauts.

关键词： monocular camera astronaut pose estimation camera calibration

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Bibliometric analysis of research challenges and trends in urban underground space

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deep Underground Science and Engineering 2024年第2期3卷 207-215页

作者： you Zhang liang Zheng Lingling He Yuyong Jiao Hanfa Peng Ranjith PGamage Faculty of Engineering China University of GeosciencesWuhanChina department of Civil Engineering Monash UniversityClaytonVictoriaAustralia Sinohydro Engineering Bureau Co. LtdPower ChinaXiningChina 4Wuhan Geomatic InstituteWuhanChina

The utilization and development of urban underground space play a crucial role in optimizing the layout of civic architecture and enhancing the urban ecological environment,which contributes toward increasing the overall carrying capacity and promoting sustainable development in megacities.To delve into the research progress of urban underground space,knowledge maps were created using the information visualization software VOSviewer.The literature was systematically extracted from three prominent databases,namely,Web of Science,Scopus,and China National Knowledge Infrastructure.According to the bibliometric analysis of the co-citation and core words co-occurrence,the trends and challenges of research on urban underground space were identified.As highlighted by the results obtained,it still remains highly challenging to achieve interdisciplinary collaboration in urban underground space research;the research trends of urban underground space consist of collaborative planning and whole life cycle sustainable development,multisource geological data informatization and resource evaluation,infrastructure design optimization,and intelligent construction.The knowledge map,drawn using bibliometric methods,offers a quantitative analysis of literature retrieval across various levels.It is recognized as an essential tool for exploring and identifying challenges and trends in urban underground space.

关键词： bibliometric analysis knowledge groups urban underground space VOSviewer

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Single thiolate replacement of metal nanoclusters

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Science China Chemistry 2024年第2期67卷 523-528页

作者： Ambreen Ambreen Yue Zhou Wanmiao Gu Qing you liang Fang Guoqing Bian Nan Yan Nan Xia Zhikun Wu Key Laboratory of Materials Physics Anhui Key Laboratory of Nanomaterials and NanotechnologyInstitute of Solid State PhysicsHefei Institutes of Physical Science(HFIPS)Chinese Academy of SciencesHefei230031China University of Science and Technology of China Hefei230601China Institute of Physical Science and Information Technology Anhui UniversityHefei230601China

Surface thiolates play important roles in evincing the structures and properties of thiolated metal nanoclusters—one type of recently emerging inorganic-organic hybrids,and thus the thiolate substitution,especially single thiolate substitution,is highly desirable for subtly tailoring the structures and properties of metal nanoclusters.However,such a single-thiolate substituting is challenging,and its influence on the metal-metal and metal-sulfur bonds remains mysterious due to the absence of the singlethiolate-substituted structure.Here,we developed a combined method,concurrently synthesized the single-thiolate-substituted nanocluster and its parent nanocluster,and successfully resolved their structures by single crystal X-ray crystallography,which reveals that the single thiolate substitute has an obvious influence on the metal-metal and metal-sulfur bond lengths although it has no effect on the absorption profile.Interestingly,the metal-metal and metal-sulfur bonds show various thermal extensibility and even the negative thermal expansion phenomena of the Au–S bond were observed in the single-thiolate-substituted nanocluster.The bond length-related stability was also observed.Overall,this study highlights a novel synthesis method and offers novel structural insights and an in-depth structure-property correlation of thiolated metal nanoclusters.

关键词： metal nanoclusters single thiolate replacement thermal expansion stability intercluster interaction

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Effects of vitamin family members on insulin resistance and diabetes complications

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World Journal of Diabetes 2024年第3期15卷 568-571页

作者： Hong-Jin Chen Min Wang Ding-Min Zou Gui-you liang Si-Yuan Yang Division of Cardiac Surgery Guizhou Institute of Precision MedicineThe Affiliated Hospital of Guizhou Medical UniversityGuiyang 550009Guizhou ProvinceChina Translational Medicine Research Center Guizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina School of Basic Medical Sciences/School of Biology and Engineering Guizhou Medical UniversityGuiyang 550025Guizhou ProvinceChina

The following letter to the editor highlights the article“Effects of vitamin D supplementation on glucose and lipid metabolism in patients with type 2 diabetes mellitus and risk factors for insulin resistance”in World J Diabetes 2023 Oct 15;14(10):1514-1523.It is necessary to explore the role of vitamin family members in insulin resistance and diabetes complications.

关键词： Vitamin Insulin resistance Diabetes complications Letter

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Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 700-706页

作者： Li Zhang Hai-Zhang you Guo-Hui Wang Wei Xu Jian-Shan Li Qing-liang Zhao Shu Du department of Hospital-Acquired Infection Control Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina department of Administrative Office Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina department of Clinical Laboratory Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina department of Pharmacy Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina department of Corneal and Lacrimal Passage Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina department of Fundus Diseases and Ocular Trauma Lixiang Eye Hospital of Soochow UniversitySuzhou 215021Jiangsu ProvinceChina

AIM:To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs.METHODS:The clinical data of 155 patients were retrospectively collected in this study,and the pathogenic bacteria species and drug resistance of each pathogenic bacteria were analyzed.RESULTS:Among the 155 patients(age from 12 to 87 years old,with an average age of 57,99 males and 56 females)with eye infections(160 eyes:74 in the left eye,76 in the right eye and 5 in both eyes,all of which were exogenous),71(45.81%)strains were gram-positive bacteria,23(14.84%)strains were gram-negative bacteria and 61(39.35%)strains were fungi.Gram-positive bacteria were highly resistant to penicillin and erythromycin(78.87%and 46.48%respectively),but least resistant to vancomycin at 0.Gram-negative bacteria were highly resistant to cefoxitin and compound sulfamethoxazole(100%and 95.65%respectively),but least resistant to meropenem at 0.Comparison of the resistance of gram-positive and gram-negative bacteria to some drugs revealed statistically significant differences(Pdermidis was the most common strain in the conjunctiva,cornea,aqueous humor or vitreous body and other eye parts.Besides,Fusarium and Pseudomonas aeruginosa were also among the most common strains of conjunctival and corneal infections.CONCLUSION:Gram-positive bacteria are the dominant bacteria in eye infections,followed by gram-negative bacteria and fungi.Considering the resistance of gramnegative bacteria to multiple drugs,monitoring of bacteria should be strengthened in eye bacterial infections for effective prevention and control to reduce complications caused by eye infections.

关键词： eye infection pathogenic bacteria drug resistance antimicrobial sensitivity test

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