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Lithofacies palaeogeography of the Late Permian Wujiaping Age in the Middle and Upper Yangtze Region,China

Journal of Palaeogeography 2014年第4期3卷 384-409页

作者： Jin-Xiong Luo you-bin he Rui Wang School of Geosciences Yangtze University

The lithofacies palaeogeography of the Late Permian Wujiaping Age in Middle and Upper Yangtze Region was studied based on petrography and the ＂single factor analysis and multifactor comprehensive mapping＂ method. The Upper Permian Wujiaping Stage in the Middle and Upper Yangtze Region is mainly composed of carbonate rocks and clastic rocks, with lesser amounts of siliceous rocks, pyroclastic rocks, volcanic rocks and coal. The rocks can be divided into three types, including clastic rock, clastic rock-limestone and limestone-siliceous rock, and four fundamental ecological types and four fossil assemblages are recognized in the Wujiaping Stage. Based on a petrological and palaeoecological study, six single factors were selected, namely, thickness （m）, content （%） of marine rocks, content （%） of shallow water carbonate rocks, content （%） of biograins with limemud, content （%） of thinbedded siliceous rocks and content （%） of deep water sedimentary rocks. Six single factors maps of the Wujiaping Stage and one lithofacies palaeogeography map of the Wujiaping Age were composed. Palaeogeographic units from west to east include an eroded area, an alluvial plain, a clastic rock platform, a carbonate rock platform where biocrowds developed, a slope and a basin. In addition, a clastic rock platform exists in the southeast of the study area. Hydro- carbon source rock and reservoir conditions were preliminarily analyzed based on lithofacies palaeogeography. Sedimentary environments have obvious controls over the development of the resource rocks. With regard to the abundance of organic matter, the hydrocarbon potential of the coastal swamp environment is the best, followed by the basin environment and the carbonate rock platform. The gas reservoir types of the Wujiaping Stage can be classified as conventional and unconventional gas reservoirs, like coal bed gas and shale gas; all of them have well exploration prospects.

关键词： Middle and Upper Yangtze Region Permian Wujiaping Stage lithofacies palaeogeography single factor analysis

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Reply to Shanmugam,G.“Review of research in internal-wave and internal-tide deposits of China:Discussion”

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Journal of Palaeogeography 2014年第4期3卷 351-358页

作者： Zhen-Zhong Gao you-bin he Xiang-Dong Li Tai-Zhong Duan School of Geosciences Yangtze University School of Land Resource Engineering Kunming University of Science and Technology Petroleum Production and Research Institute of SINOPEC

We are glad to know that our paper ＂Review of research in internal-wave and internal-tide deposits of China＂（Gao et al., 2013） published in Journal of Palaeogeography has attracted close attention of international peers, and we noted that Shanmugam has provided a critical assessment of our paper. he claimed that ＂interpretations of ten ancient exam- ples in China and one in the central Appalachians （USA） as deep-water deposits of internal waves and internal tides are unsustainable＂, among many other comments and criticisms, and he concluded that ＂any interpretation of ancient strata as deposits of internal waves and internal tides is premature＂. This article is aimed at responding to his major criticisms. We believe that constructive discussions will benefit the development of the study in internal-wave and internal-tide deposits. Unfortunately, Shanmugam seems not to follow this line of scientific criticism, but is trying to reject all research results in this subject based on his illogical and inconsistent reasoning, and distortion of others＇ points of view. In this article, with facts and evidences, we will refuse the main wrong assertions of Shanmugam＇s, for example, ＂the use of bidirectional cross-bedding as evidence for deposition by baroclinic currents in outcrop studies is sedimentologically erroneous ＂ and ＂any interpretation of ancient strata as deposits of internal waves and internal tides is premature＂. We will also use typical characteristics of the ancient examples to demonstrate that they are certainly not turbidites, or contourites, or tsunami-related deposits, but internal-wave and internal-tide deposits as the most plausible to defend the rationality of our interpretation in our previous papers.

关键词： internal-wave and internal-tide deposits bidirectional cross-bedding sedi- mentary succession critical assessment

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Quantitative lithofacies palaeogeography

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Journal of Palaeogeography 2014年第1期3卷 1-34页

作者： Zeng-Zhao Feng Xiu-Juan Zheng Zhi-Dong Bao Zhen-Kui Jin Sheng-he Wu you-bin he Yong-Min Peng Yu-Qing Yang Jia-Qiang Zhang Yong-Sheng Zhang China University of Petroleum (Beijing) School of Geosciences Yangtze University Research Institute of Exploration and Development SINOPEC China Oilfield Services Limited of CNOOC Ltd. Oil and Gas Research Center China Geological Survey Chinese Academy of Geological Sciences

Quantitative lithofacies palaeogeography is an important discipline of *** is developed on the foundation of traditional lithofacies palaeogeography and palaeogeography,the core of which is the quantitative lithofacies palaeogeographic *** means that in the palaeogeographic map,the division and identification of each palaeogeographic unit are supported by quantitative data and quantitative fundamental *** lithofacies palaeogeographic maps are quantitative or mainly quantitative.A great number of quantitative lithofacies palaeogeographic maps have been published,and articles and monographs of quantitative lithofacies palaeogeography have been published successively,thus the quantitative lithofacies palaeogeography was formed and *** is an important development in lithofacies *** composing quantitative lithofacies palaeogeographic maps,the key measure is the single factor analysis and multifactor comprehensive mapping method—methodology of quantitative lithofacies *** this paper,the authors utilize two case studies,one from the Early Ordovician of South China and the other from the Early Ordovician of Ordos,North China,to explain how to use this methodology to compose the quantitative lithofacies palaeogeographic maps,and to discuss the palaeogeographic units in these ***,three characteristics,i.e.,quantification,multiple orders and multiple types,of quantitative lithofacies palaeogeographic maps are conclusively discussed.

关键词： quantitative lithofacies palaeogeography single factor analysis multifactor comprehensive mapping Early Ordovician three characteristics

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Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model

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Neural Regeneration Research 2025年第3期20卷 858-872页

作者： Xintian Ding Chun Chen heng Zhao bin Dai Lei Ye Tao Song Shuai Huang Jia Wang Tao you Department of Orthopedics The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Orthopedics Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui ProvinceChina

Reducing the secondary inflammatory response, which is partly mediated by microglia, is a key focus in the treatment of spinal cord injury. Src homology 2-containing protein tyrosine phosphatase 2(SHP2), encoded by PTPN11, is widely expressed in the human body and plays a role in inflammation through various mechanisms. Therefore, SHP2 is considered a potential target for the treatment of inflammation-related diseases. However, its role in secondary inflammation after spinal cord injury remains unclear. In this study, SHP2 was found to be abundantly expressed in microglia at the site of spinal cord injury. Inhibition of SHP2 expression using siRNA and SHP2 inhibitors attenuated the microglial inflammatory response in an in vitro lipopolysaccharide-induced model of inflammation. Notably, after treatment with SHP2 inhibitors, mice with spinal cord injury exhibited significantly improved hind limb locomotor function and reduced residual urine volume in the bladder. Subsequent in vitro experiments showed that, in microglia stimulated with lipopolysaccharide, inhibiting SHP2 expression promoted M2 polarization and inhibited M1 polarization. Finally, a co-culture experiment was conducted to assess the effect of microglia treated with SHP2 inhibitors on neuronal cells. The results demonstrated that inflammatory factors produced by microglia promoted neuronal apoptosis, while inhibiting SHP2 expression mitigated these effects. Collectively, our findings suggest that SHP2 enhances secondary inflammation and neuronal damage subsequent to spinal cord injury by modulating microglial phenotype. Therefore, inhibiting SHP2 alleviates the inflammatory response in mice with spinal cord injury and promotes functional recovery postinjury.

关键词： apoptosis glycolysis inflammatory response microglia neurons polarization spinal cord injury Src homology 2-containing protein tyrosine phosphatase 2

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong Lee Su bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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Resistance of Cement-based Grouting Materials with Nano- SiO_(2) Emulsion to Chloride Ion Penetration

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 114-119页

作者： LI Shuiping CheNG Jian WEI Chao YUAN bin YU Chengxiao College of Architectural Science and Engineering Yangzhou UniversityYangzhou 225127China

The chloride penetration resistance of cement-based grout materials was improved by nano-silica *** of mixtures containing different nano-silica particles or emulsions were exposed in sodium chloride solutions of specific concentrations with different test *** properties of the mixes were assessed in terms of weight loss and compressive strength.X-ray diffraction(XRD)and scanning electron microscopy(SEM)of mixes were performed to analysis the phase evolution and *** results demonstrated that the introduction of nano-SiO_(2) emulsion significantly decreased the compressive strength loss and calcium hydroxide(CH)crystal content of hydration production,and then enhanced the resistance of cement-based grouting materials to chloride ion *** improvement derives from the filling and pozzolanic effects of nano-SiO_(2) particles,which were incorporated via an emulsion and attributed to a well dispersion in grouting matrix.

关键词： grouting materials nano-SiO_(2)emulsion chloride ion penetration,weight loss strength loss

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Wave effect of gravitational waves intersected with a microlens field Ⅱ:An adaptive hierarchical tree algorithm and population study

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 241-254页

作者： Xikai Shan Guoliang Li Xuechun Chen Wen Zhao bin Hu Shude Mao Department of Astronomy Tsinghua University Purple Mountain Observatory Chinese Academy of Sciences Institute for Frontier in Astronomy and Astrophysics Beijing Normal University School of Physics and Astronomy Beijing Normal University School of Astronomy and Space Science University of Science and Technology of China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of Astronomy University of Science and Technology of ChinaChinese Academy of Sciences

The gravitational lensing wave effect generated by a microlensing field embedded in a lens galaxy is an inevitable phenomenon in strong lensed gravitational waves （SLGWs）.This effect presents both challenges and opportunities for the detection and application of ***,investigating this wave effect requires computing a complete diffraction integral over each microlens in the *** is extremely time-consuming due to the large number of microlenses （10～3-10～6）.Therefore,simply adding all the microlenses is ***,the complexity of the time delay surface makes the lens plane resolution a crucial factor in controlling numerical *** this paper,we propose a trapezoid approximation-based adaptive hierarchical tree algorithm to meet the challenges of calculation speed and *** find that this algorithm accelerates the calculation by four orders of magnitude compared to the simple adding method and is one order of magnitude faster than the fixed hierarchical tree algorithm proposed for electromagnetic *** importantly,our algorithm ensures controllable numerical errors,increasing confidence in the *** with our previous work （***.66,239511,2023）,this paper addresses all numerical issues,including integral convergence,precision,and computational time1).Finally,we conducted a population study on the microlensing wave effect of SLGWs using this algorithm and found that the microlensing wave effect cannot be ignored,especially for Type II SLGWs （from saddle position of the time delay surface） due to their intrinsic geometric structures and their typical intersection with a denser microlensing ***,more than 33%（11%） of SLGWs have a mismatch larger than 1%（3%） compared to the unlensed ***,we found that the mismatch between signal pairs in a doubly imaged GW is generally larger than 10-3,and 61%（25%） of signal pairs have a mismatch larger than 1%（3%）.Therefo

关键词： gravitational lensing diffractional integral algorithm gravitational wave

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Recent Advances in Artificial Sensory Neurons:Biological Fundamentals,Devices,Applications,and Challenges

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Nano-Micro Letters 2025年第3期17卷 168-216页

作者： Shuai Zhong Lirou Su Mingkun Xu Desmond Loke bin Yu Yishu Zhang Rong Zhao Guangdong Institute of Intelligence Science and Technology HengqinZhuhai 519031People’s Republic of China College of Integrated Circuits Zhejiang UniversityHangzhou 3112000People’s Republic of China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 310027People’s Republic of China Department of Science Mathematics and TechnologySingapore University of Technology and DesignSingapore 487372Singapore Department of Precision Instruments Tsinghua UniversityBeijing 100084People’s Republic of China Center for Brain‑Inspired Computing Research Tsinghua UniversityBeijing 100084People’s Republic of China IDG/McGovern Institute for Brain Research Tsinghua UniversityBeijing 100084People’s Republic of China

Spike-based neural networks,which use spikes or action potentialsto represent information,have gained a lot of attention because of their high energyefficiency and low power *** fully leverage its advantages,convertingthe external analog signals to spikes is an essential *** including analog-to-digital converters or ring oscillators,and sensorssuffer from high power and area *** efforts are devoted to constructingartificial sensory neurons based on emerging devices inspired by the biologicalsensory *** can simultaneously perform sensing and spike conversion,overcoming the deficiencies of traditional sensory *** review summarizesand benchmarks the recent progress of artificial sensory *** starts with thepresentation of various mechanisms of biological signal transduction,followed bythe systematic introduction of the emerging devices employed for artificial ***,the implementations with different perceptual capabilitiesare briefly outlined and the key metrics and potential applications are also ***,we highlight the challenges and perspectives for the future development of artificial sensory neurons.

关键词： Artificial intelligence Emerging devices Artificial sensory neurons Spiking neural networks Neuromorphic sensing

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Visualizing charge transfer and nuclear quantum effects in the hydrogen bond network of water

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Science China Chemistry 2025年

作者： Ying Gao Haotian Wang bin Zhang Department of Chemistry School of Science Tianjin University

Water, one of the most common and important solvents on earth, is widely used in biology, physics, chemistry, and other fields [1]. The hydrogen bond interactions between water molecules form a highly dynamic and syne...

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Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi Guo bin Hu Haiwen Luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

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