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Taking the pulse of COVID-19:a spatiotemporal perspective

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International Journal of Digital Earth 2020年第10期13卷 1186-1211页

作者： Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou you zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding NSF Spatiotemporal Innovation Center George Mason Univ.FairfaxVAUSA Department of Geography and GeoInformation Science George Mason Univ.FairfaxVAUSA Department of Geographical Sciences University of MarylandCollege ParkMDUSA Center for Geographic Analysis Harvard UniversityCambridgeMAUSA Geoinformation and Big Data Research Lab Department of GeographyUniversity of South CarolinaColumbiaSCUSA Chinese Academy of Surveying and Mapping BeijingPeople’s Republic of China School of Resource and Environmental Sciences Wuhan UniversityWuhanPeople’s Republic of China Cloud Computeand Storage OperationsInformation Technology ServicesGeorge Mason UniversityFairfaxVAUSA Department of Geography Pennsylvania State UniversityState CollegePAUSA School of Business Management East China Normal UniversityShanghaiPeople’s Republic of China School of Mathematical Sciences East China Normal UniversityShanghaiPeople’s Republic of China Department of Psychology George Mason UniversityFairfaxVAUSA mDepartment of Computer Science George Mason UniversityFairfaxVAUSA Department of Information Technology George Mason UniversityFairfaxVAUSA Department of Biology George Mason UniversityFairfaxVAUSA College of Land Science and Technology China Agricultural UniversityBeijingPeople’s Republic of China China Data Institute Ann ArborMIUSA Institute of Remote Sensing and GIS Peking UniversityBeijingPeople’s Republic of China Aerospace Information Research Institute Chinese Academy of SciencesBeijingPeople’s Republic of China School of Geomatics and Urban Spatial Informatics Beijing University of Civil Engineering and ArchitectureBeijingPeople’s Republic of China School of Geographical Sciences Nanjing University of Information Science&TechnologyNanjingPeople’s Republic of China School of Geodesy and Geomatics Wuhan UniversityWuhanPeople’s Republic of China wFaculty of Environment University of WaterlooWaterlooCanada

The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the *** transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and *** response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global *** perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies.

关键词： Big Data Earth system emergency geospatial sciences epidemics applications

Construction of hydrangea-like core-shell SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres for tunable electromagnetic wave absorbers

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Journal of Advanced Ceramics 2023年第4期12卷 711-723页

作者： Huanhuan Niu Xuewen Jiang Yongde Xia Hailong Wang Rui Zhang Hongxia Li Bingbing Fan Yanchun zhoua School of Material Science&Engineering Zhengzhou UniversityZhengzhou 450001China Department of Engineering University of ExeterExeter EX44SBUK School of Materials Science and Engineering Luoyang Institute of Science and TechnologyLuoyang 471023China Sinostel Luoyang Institute of Refractories Research Co. Ltd.Luoyang 471039China

Ti_(3)C_(2)T_(x)MXene shows great potential in the application as microwave absorbers due to its high attenuation ***,excessively high permittivity and self-stacking are the main obstacles that constrain its wide range of *** tackle these problems,herein,the microspheres of SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi with the hydrangea-like core-shell structure were designed and prepared by a combinatorial electrostatic assembly and hydrothermal reaction *** microspheres are constructed by an outside layer of CoNi nanosheets and intermediate Ti_(3)C_(2)T_(x)MXene nanosheets wrapping on the core of modified SiO_(2),engendering both homogenous and heterogeneous *** trilayer SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres are“magnetic microsize supercapacitors”that can not only induce dielectric loss and magnetic loss but also provide multilayer interfaces to enhance the interfacial *** optimized impedance matching and core-shell structure could boost the reflection loss(RL)by electromagnetic *** synthesized SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres demonstrate outstanding microwave absorption(MA)performance benefited from these *** obtained RL value was-63.95 dB at an ultra-thin thickness of 1.2 mm,corresponding to an effective absorption bandwidth(EAB)of 4.56 *** work demonstrates that the trilayer core-shell structure designing strategy is highly efficient for tuning the MA performance of MXene-based microspheres.

关键词： SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi hydrangea-like core-shell structure spherical capacitor high-performance microwave absorption(MA) interfacial polarization impedance match

Enhanced tensile properties in a Mg-6Gd-3Y-0.5Zr alloy due to hot isostatic pressing(HIP)

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Journal of Materials Science & Technology 2019年第9期35卷 1860-1868页

作者： B. zhoua D.Wu R.S.Chen En-hou Han The Group of Magnesium Alloys and Their applications Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

Hot isostatic pressing (HIP) was applied to Mg-6Gd-3Y-0.5Zr (GW63) alloy to reduce shrinkage porosity, thus, to enhance the integrity and reliability of castings. During HIP process, shrinkage porosity was closed by grain compatible deformation and subsequent diffusion across the bonding interface. The amount of initial shrinkage porosity was the key factor for shrinkage porosity closure. HIP was testified to be effective on shrinkage porosity reduction in GW63 alloy due to its relatively narrow solidification range and resultant low content of initial shrinkage porosity in most sections, leading to higher tensile properties both in as-cast and cast-T6 condition. The improvement in tensile properties was mainly because of shrinkage porosity reduction and resultant effective rare-earth (RE) elements homogenization and precipitation strengthening.

关键词： Hot isostatic pressing Mg-Gd-Y-Zr Shrinkage porosity reduction Tensile properties

Crystal structure of a bacterial homolog to human lysosomal transporter,spinster

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Science Bulletin 2019年第18期64卷 1310-1317页

作者： Fu zhoua Deqiang Yao Bing Rao Li Zhang Wang Nie Yan Zou Jie Zhao Yu Cao CAS Center for Excellence on Molecular Cell Science Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 201210China Institute of Precision Medicine The Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200125China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Department of Orthopaedics Shanghai Key Laboratory of Orthopaedic ImplantShanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Lysosomes break down various biomolecules and spinster is one of the major efflux carriers removing degradation products from lysosomal lumen to keep it in healthy size and proper *** it is well established that a dysfunctional spinster will cause enlarged lysosomes and in turn lead to developmental defects and abnormal behavior in animals,little was known about the transportation mechanism and substrate specificity of ***,we report a crystal structure of spinster homolog from Hyphomonas neptunium,HnSPNS,in its inward-facing conformation with and without substrate *** is crystallized in a monomer and a substrate-binding cavity was formed in the center of its transmembrane helices.A blob of electron density corresponding to its substrate was found in the cavity near a conserved residue,R42,which is locked in position by the interactions with conserved residues E129 and *** results suggest that human spinster serves as a transporter translocating negativelycharged lipophilic small molecules and E129 might serve as a switch to control the conformational change via its protonation-deprotonation cycle.

关键词： Major facilitator superfamily Transporter Spinster Membrane protein

Effects of support pore size on new Cs_(2.5)H_(0.5)PW_(12)O_(40)/SiO_2 catalysts for the ring-opening polymerization of tetrahydrofuran

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Chinese Chemical Letters 2009年第3期20卷 344-347页

作者： Xue Mei Liao Wei Chu Yang Li FU Dong zhoua Shi Zhong Luo Department of Chemical Engineering Sichuan University Chengdu 610065 China Research Institute of Natural Gas Technology Petrochina Southwest Oil and Gas Field Company Chengdu 610213 China

Mesoporous silica supported Cs2.5H0.5PW12O40 catalysts were prepared by impregnation method, and several silica supports with different pore size were utilized. N2 adsorption, XRD and ICP-AES techniques were utilized to characterize the silica supports and catalysts. XRD results showed that the dispersion of Cs2.5H0.5PW12 was better for the silica support with larger pore size. The catalytic activity results showed that the pore size played important role on the catalyst activity and the molecular weight of PTHF. When Cs2.5H0.5PW12O40 was dispersed on larger pore size silica support, the catalysts showed good performances for the synthesis of PTHE The molecular weight of PTHF product on the sample in which Cs2.5H0.5PW12O40 was dispersed on larger pore support was higher than that on the catalyst with smaller pore support. The leaching amounts of the active components for the supported Cs2.5H0.5PW12O40 catalysts were much lower. After five reaction cycles, there were still good activities and stabilities for the supported Cs2.5H0.5PW12O40 catalysts with larger pore silica supports. These results were much better than those of the supported heteropolyacid H3PW12O40 catalyst.

关键词： PTHF synthesis Cs2.5H0.5PW12O40 catalysts Mesoporous silica Pore size Stability

Implementing an innovated liver ex-situ machine perfusion technology:The 2018 Joint International Congress of ILTS,ELITA and LICAGE

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 283-285页

作者： Jun-Jun Jia Jian-Hui Li Hai-Yang Xie Lin zhoua Shu-Sen Zheng Division of Hepatobiliary Pancreatic Surgery First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Combined Multi-Organ Transplantation Ministry of Public HealthFirst Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

The 2018 Joint International Congress of ILTS,ELITA and LICAGE were held in Lisbon,Portugal on May 23–26,*** exciting and innovative program brought together 1144 experts in liver transplantation(LT)such as surgeons,physicians or basic scientists from 61 *** presentations included 110 invited speakers,181 oral presentations,and 545 *** editorial highlights some of the most innovative and impactful presentations in

关键词： NMP WIT DCD Implementing an innovated liver ex-situ machine perfusion technology:The 2018 Joint International Congress of ILTS,ELITA and LICAGE

nvolvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis

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Protein & Cell 2015年第8期6卷 589-598页

作者： Haiyan Chu Ting Wu Wenyu Wu Wenzhen Tu Shuai Jiang Sidi Chen Yanyun Ma Qingmei Liu Xiaodong zhoua Li Jin Jiucun Wang Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering Collaborative Innovation Center for Genetics and Development School of Life Sciences and Institutes of Biomedica Sciences Fudan University Shanghai 200438 China Division of Dermatology Huashan Hospital Fudan University Shanghai 200040 China Division of Rheumatology Shanghai TCM-Integrated Hospital Shanghai 200082 China Division of Rheumatology University of Texas Health Science Center at Houston Houston TX 77030 USA Institute of Rheumatology Immunology and Allergy Fudan University Shanghai 20080 China

Uncontrolled fibrosis of skin and internal organs is the main characteristic of scleroderma, and collagen is a major extracellular matrix protein that deposits in the fibrotic organs. As the chaperone of collagen, heat shock protein 47 （HSP47） is closely related with the development of fbrosis. To explore the potential func- tion of HSP47 in the pathogenesis of scleroderma, the clinical, in vivo and in vitro studies were performed. In clinical, the increased mRNA level of HSP47 was observed in the skin fibroblasts and PBMC from scle- roderma patients, and the enhanced protein level of HSP47 was also detected in the skin biopsy and plasma of the above patients. Unexpectedly, the enhanced levels of HSP47 were positively correlated with the presence of anti-centromere antibody in scleroderma patients. Moreover, a high expression of HSP47 was found in the skin lesion of BLM-induced scleroderma mouse model. Further in vitro studies demonstrated that HSP47 knockdown could block the intracellular and extracellular collagen over-productions induced by exogenous TGF-13. Therefore, the results in this study provide direct evidence that HSP47 is involved in the pathogenesis of scleroderma. The high expression of HSP47 can be detected in the circulatory system of scleroderma patients, indicating that HSP47 maybecome a pathological marker to assess the progres- sion of scleroderma, and also explain the systemic fibrosis of scleroderma. Meanwhile, collagen over-ex- pression is blocked by HSP47 knockdown, suggesting the possibility that HSP47 can be a potential therapeutic target for scleroderma.

关键词： systemic sclerosis fibrosis collagenheat shock protein 47 anti-centromere antibody,therapeutic target

Optimization of N18 Zirconium Alloy for Fuel Cladding of Water Reactors

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Journal of Materials Science & Technology 2012年第7期28卷 606-613页

作者： B.X. Zhou M. Y. Yao Z.K. Li X.M. Wang J. zhoua C.S. Long Q. Liu B.F. Luan Laboratory for Mierostructures Shanghai University Shanghai 200444 China Institute of Materials Shanghai University Shaxighai 200072 China Northwest Institute for Non-ferrous Metal Research Xian 721014 China Key Laboratory for Nuclear Fuel and Materials Nuclear Power Institute of China Chengdu 610041 China College of Material Science and Engineering Chongqing University Chongqing 400044 China

In order to optimize the microstructure and composition of N18 zirconium alloy （Zr-1Sn-0.35Nb-0.35Fe-0.1Cr, in mass fraction, %）, which was developed in China in 1990s, the effect of microstructure and composition variation on the corrosion resistance of the N18 alloy has been investigated. The autoclave corrosion tests were carried out in super heated steam at 400 ~C/10.3 MPa, in deionized water or lithiated water with 0.01 mol/L LiOH at 360 ~C/18.6 MPa. The exposure time lasted for 300-550 days according to the test temperature. The results show that the microstructure with a fine and uniform distribution of second phase particles （SPPs）, and the decrease of Sn content from 1% （in mass fraction, the same as follows） to 0.8% are of benefit to improving the corrosion resistance; It is detrimental to the corrosion resistance if no Cr addition. The addition of Nb content with upper limit （0.35%） is beneficial to improving the corrosion resistance. The addition of Cu less than 0.1% shows no remarkable influence upon the corrosion resistance for N18 alloy. Comparing the corrosion resistance of the optimized N18 with other commercial zirconium alloys, such as Zircaloy-4, ZIRLO, E635 and Ell0, the former shows superior corrosion resistance in all autoclave testing conditions mentioned above. Although the data of the corrosion resistance as fuel cladding for high burn-up has not been obtained yet, it is believed that the optimized N18 alloy is promising for the candidate of fuel cladding materials as high burn-up fuel assemblies. Based on the theory that the microstructural evolution of oxide layer during corrosion process will affect the corrosion resistance of zirconium alloys, the improvement of corrosion resistance of the N18 alloy by obtaining the microstructure with nano-size and uniform distribution of SPPs, and by decreasing the content of Sn and maintaining the content of Cr is discussed.

关键词： Zirconium alloys Corrosion resistance Composition variation Microstructure

Structural,Electronic,Optical and Thermodynamic Properties of Nanolaminated Boride Cr_4AlB_6

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Chinese Journal of Structural Chemistry 2018年第10期37卷 1572-1584页

作者：张瑞州崔红玲李小红 College of Physics and Engineering Henan University of Science and TechnologyLuoyang471003China Henan Key Laboratory of Photoelectric Energy Storage Materials and Applications Luoyang 471023China

Density functional calculations were used to investigate the structural,electronic,optical and thermal properties of Cr_4AlB_*** optimized lattice constants and atomic positions accord well with the experimental *** analysis of band structure and density of states confirms the metallic nature of Cr_4AlB_*** static dielectric constant e1（0） is about 128.0,and the maximum optical conductivity occurs at about 8.12 *** the photon energy range from 7.87 to 23.48 e V,Cr_4AlB_6 presents a metal reflective *** plasma resonance frequency wp of Cr_4AlB_6 is at the photon energy of 23.85 eV,and Cr_4AlB_6 will be transparent and change from metallic to dielectric response if the incident light has frequency greater than the plasma frequency of Cr_4AlB_*** properties including the primitive cell volume and thermal expansion,the bulk modulus and heat capacity Cv were further investigated with the increasing temperature and pressure by using the quasi-harmonic Debye model.

关键词： electronic structure optical property thermodynamic property band structure first-principles calculations