检索结果-南通市图书馆

Photodynamic and photothermal therapies for bacterial infection treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Smart Molecules

Smart Molecules 2023年第1期1卷 24-36页

作者： Heejeong Kim you rim lee Hyunsun Jeong Jiah lee Xiaofeng Wu Haidong Li Juyoung Yoon Department of Chemistry and Nanoscience Ewha Womans UniversitySeoulKorea School of Bioengineering Dalian University of TechnologyDalianChina

Bacteria can cause numerous infectious diseases and has been a major threat to human *** antibiotics have partially succeeded in treating bacteria,owing to antibiotic abuse,the emergence of multidrug-resistant(MDR)bacteria has drastically diminished their *** the invention of laser,the combination of light and photosensitizers,photodynamic therapy(PDT),has become an effective noninvasive treatment along with photothermal therapy(PTT),in which heat is generated by nonradiative *** PDT and PTT are emerging as effective treatments for bacterial infection,particularly against MDR *** mini review covers the recent progresses in PDT and PTT for bacterial treatment.

关键词： AIEgens antibacterial phototherapy photodynamic therapy photothermal therapy phthalocyanine

Discovering High-Quality Threaded Discussions in Online Forums

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computer Science & Technology 2014年第3期29卷 519-531页

作者： Jung-Tae lee Min-Chul Yang Hae-Chang rim Department of Computer and Radio Communications Engineering Korea UniversitySeoul 136-713Korea

Archives of threaded discussions generated by users in online forums and discussion boards contain valuable knowledge on various topics. However, not all threads are useful because of deliberate abuses, such as trolling and flaming, that are commonly observed in online conversations. The existence of various users with different levels of expertise also makes it difficult to assume that every discussion thread stored online contains high-quality contents. Although finding high-quality threads automatically can help both users and search engines sift through a huge amount of thread archives and make use of these potentially useful resources effectively, no previous work to our knowledge has performed a study on such task. In this paper, we propose an automatic method for distinguishing high-quality threads from low-quality ones in online discussion sites. We first suggest four different artificial measures for inducing overall quality of a thread based on ratings of its posts. We then propose two tasks involving prediction of thread quality without using post rating information. We adopt a popular machine learning framework to solve the two prediction tasks. Experimental results on a real world forum archive demonstrate that our method can significantly improve the prediction performance across all four measures of thread quality on both tasks. We also compare how different types of features derived from various aspects of threads contribute to the overall performance and investigate key features that play a crucial role in discovering high-quality threads in online discussion sites.

关键词： online forum discussion board thread quality

Malicious Traffic Compression and Classification Technique for Secure Internet of Things

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第9期76卷 3465-3482页

作者： Yu-rim lee Na-Eun Park Seo-Yi Kim Il-Gu lee Department of Future Convergence Technology Engineering SungshinWomen’s UniversitySeoul02844Korea Department of Convergence Security Engineering SungshinWomen’s UniversitySeoul02844Korea

With the introduction of 5G technology,the application of Internet of Things(IoT)devices is expanding to various industrial ***,introducing a robust,lightweight,low-cost,and low-power security solution to the IoT environment is ***,this study proposes two methods using a data compression technique to detect malicious traffic efficiently and accurately for a secure IoT *** first method,compressed sensing and learning(CSL),compresses an event log in a bitmap format to quickly detect ***,the attack log is detected using a machine-learning classification *** second method,precise re-learning after CSL(Ra-CSL),comprises a two-step *** uses CSL as the 1st step analyzer,and the 2nd step analyzer is applied using the original dataset for a log that is detected as an attack in the 1st step *** the experiment,the bitmap rule was set based on the boundary value,which was 99.6%true positive on average for the attack and benign data found by analyzing the training *** results showed that the CSL was effective in reducing the training and detection time,and Ra-CSL was effective in increasing the detection *** to the experimental results,the data compression technique reduced the memory size by up to 20%and the training and detection times by 67%when compared with the conventional *** addition,the proposed technique improves the detection accuracy;the Naive Bayes model with the highest performance showed a detection rate of approximately 99%.

关键词： IoT security intrusion detection machine learning traffic classification

Mechanisms linking gut microbial metabolites to insulin resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2021年第6期12卷 730-744页

作者： Hye rim Jang Hui-young lee Laboratory of Mitochondrial and Metabolic Diseases Department of Health Sciences and TechnologyGAIHSTGachon UniversityIncheon 21999South Korea Korea Mouse Metabolic Phenotyping Center Lee Gil Ya Cancer and Diabetes InstituteGachon UniversityIncheon 21999South Korea Division of Molecular Medicine Department of MedicineGachon University College of MedicineIncheon 21936South Korea

Insulin resistance is the rate-limiting step in the development of metabolic diseases,including type 2 *** gut microbiota has been implicated in host energy metabolism and metabolic diseases and is recognized as a quantitatively important organelle in host metabolism,as the human gut harbors 10 trillion bacterial *** microbiota break down various nutrients and produce metabolites that play fundamental roles in host metabolism and aid in the identification of possible therapeutic targets for metabolic ***,understanding the various effects of bacterial metabolites in the development of insulin resistance is ***,we review the mechanisms linking gut microbial metabolites to insulin resistance in various insulin-responsive tissues.

关键词： Insulin resistance Skeletal muscle Liver Adipose tissue Intestine Gut bacterial metabolites

Search-Based Cost-Effective Software Remodularization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computer Science & Technology 2018年第6期33卷 1320-1336页

作者： rim Mahouachi Complex Outstanding Systems Modeling Optimization and Supervision Laboratory National School of Computer Science University of Manouba 2010 Manouba Tunisia

Software modularization is a technique used to divide a software system into independent modules （packages）that are expected to be cohesive and loosely coupled. However, as software systems evolve over time to meet new require-ments, their modularizations become complex and gradually loose their quality. Thus, it is challenging to automaticallyoptimize the classes＇ distribution in packages, also known as remodularization. To alleviate this issue, we introduce a newapproach to optimize software modularization by moving classes to more suitable packages. In addition to improving designquality and preserving semantic coherence, our approach takes into consideration the refactoring effort as an objective initself while optimizing software modularization. We adapt the Elitist Non-dominated Sorting Genetic Algorithm （NSGA-Ⅱ）of Deb et al. to find the best sequence of refactorings that 1） maximize structural quality, 2） maximize semantic cohesivenessof packages （evaluated by a semantic measure based on WordNet）, and 3） minimize the refactoring effort. We report theresults of an evaluation of our approach using open-source projects, and we show that our proposal is able to produce acoherent and useful sequence of recommended refactorings both in terms of quality metrics and from the developer＇s pointsof view.

关键词： remodularization search-based software engineering refactoring effort multi-objective optimization seman-tics dependency

Will the collaboration of surgery and external radiotherapy open new avenues for hepatocellular carcinoma with portal vein thrombosis?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第7期28卷 704-714页

作者： Jung Wan Choe Hye Yoon lee Chai Hong rim Department ofInternal Medicine Korea University Ansan HospitalAnsan 15355South Korea Department of Surgery Korea University Ansan HospitalAnsan 15355South Korea Department of Radiation Oncology Korea University Ansan HospitalAnsan 15355South Korea

Portal invasion of hepatocellular carcinoma(HCC)occurs in 12.5%-40%of patients diagnosed with cancer and yields poor clinical *** it is a common cause of inoperability,sorafenib was regarded as the standard treatment for HCC in the Barcelona Clinic of Liver Cancer ***,the median survival of the Asian population was only approximately 6 mo,and the tumor response rate was less than moderate(<5%).Various locoregional modalities were performed,including external beam radiotherapy(EBRT),transarterial chemoembolization,hepatic arterial infusion chemotherapy,and surgery,alone or in *** them,EBRT is a noninvasive method and can safely treat tumors involving the major *** EBRT has been commonly performed,especially in East Asian countries,where locally invasive HCC is highly *** surgery is not commonly indicated,pioneering studies have demonstrated encouraging results in recent ***,the combination of neo-or adjuvant EBRT and surgery has been recently used and has significantly improved the outcomes of HCC patients,as reported in a few randomized *** systemic modality,a combination of novel immunotherapy and vascular endothelial growth factor inhibitor showed results superior to that of sorafenib as a first-line *** clinical trials investigating the combined use of these novel agents,surgery,and EBRT are expected to improve the prognosis of HCC with portal invasion.

关键词： Surgery Hepatocellular carcinoma Radiotherapy Systemic treatment

Wave Radiation by a Floating Body in Water of Finite Depth Using an Exact DtN Boundary Condition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2023年第6期22卷 1497-1504页

作者： rim Un-Ryong Institute of Ocean Engineering Kim Chaek University of TechnologyPyongyang 999093Democratic People’s Republic of Korea

The present paper focuses on the wave radiation by an oscillating body with six degrees of freedom by using the DtN artifi-cial boundary *** artificial boundary is usually selected as a circle or spherical surface to solve various types of fields,such as sound waves or electromagnetic waves,provided that the considered domain is infinite or unbounded in all ***,the substantial wave motion is considered in water of finite depth,that is,the fluid domain is bounded vertically but unbounded ***,the DtN boundary condition is given on an artificial cylindrical surface,which divides the water domain into an interior and exterior *** boundary integral equation is adopted to implement the present *** the case of a floating cylinder,the results of hydrodynamic coefficients of a chamfer box are discussed.

关键词： wave radiation boundary element method Dirichlet-to-Neumann map artificial boundary floating body finite-depth water

Driving inward growth of lithium metal in hollow microcapsule hosts by heteroatom‐controlled nucleation

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Carbon Energy 2024年第8期6卷 262-272页

作者： Siwon Kim Hong rim Shin Ki Jae Kim Min‐Sik Park Jong‐Won lee Division of Materials Science and Engineering Hanyang UniversitySeoulRepublic of Korea Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Energy Science Sungkyunkwan UniversitySuwonRepublic of Korea Department of Advanced Materials Engineering for Information and Electronics Integrated Education for Frontier Science and Technology(BK21 Four)Kyung Hee UniversityYonginRepublic of Korea

The application of Li metal anodes in rechargeable batteries is impeded by safety issues arising from the severe volume changes and formation of dendritic Li ***‐dimensional hollow carbon is receiving increasing attention as a host material capable of accommodating Li metal inside its cavity;however,uncontrollable and nonuniform deposition of Li remains a *** this study,we synthesize metal–organic framework‐derived carbon microcapsules with heteroatom clusters(Zn and Ag)on the capsule walls and it is demonstrated that Ag‐assisted nucleation of Li metal alters the outward‐to‐inward growth in the microcapsule ***‐incorporated microcapsules are prepared via chemical etching of zeolitic imidazole framework‐8 polyhedra and are subsequently decorated with Ag by a galvanic displacement reaction between Ag^(+) and metallic *** introduced Ag significantly reduces the energy barrier and increases the reaction rate for Li nucleation in the microcapsule host upon Li *** combined electrochemical,microstructural,and computational studies,we verify the beneficial role of Ag‐assisted Li nucleation in facilitating inward growth inside the cavity of the microcapsule host and,in turn,enhancing electrochemical *** study provides new insights into the design of reversible host materials for practical Li metal batteries.

关键词： hollow carbon hosts lithium metal batteries lithium plating metal-organic frameworks nucleation

Synergic effect of sex pheromone(7R,8S)-cis-7,8-epoxy-2-methyloctadec-17-ene on(+)-disparlure of the Asian gypsy moth,Lymantria dispar, in Korea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2019年第3期30卷 1119-1122页

作者： Il-Kwon Park Hyo-rim lee Chan-Sik Jung Sang-Hyun Koh Department of Forest Sciences Seoul National University Seoul 08826Republic of Korea Research Institute of Agriculture and Life Science College of Agriculture and Life SciencesSeoul National University Seoul 08826Republic of Korea Division of Forest Insect Pests and Diseases National Institute of Forest ScienceSeoul 02455Republic of Korea

field attraction test of (7R,8S)-cis-7,8-epoxy-2- methyloctadec-17-ene (= 7R,8S-epo-2me-17ene-18Hy), a trace component of the sex pheromone gland of the Asian gypsy moth,(Lymantria dispar), traps that were baited with the trace component attracted more L. dispar than traps baited with (7S,8R)-cis-7,8-epoxy-2-methyloctadec-17-ene (= 7S,8R-epo-2me-17ene-18Hy) and unbaited traps. However, traps baited with 7R,8S-epo-2me-17ene-18Hy were less attractive than traps baited with (+)-disparlure [=(7R,8S)-cis-7,8-epoxy-2-methyloctadecane], the sex pheromone of L. dispar. Combination tests with (?)-disparlure, 7R,8S-epo-2me-17ene-18Hy, and 7S,8R-epo-2me- 17ene-18Hy revealed that 7R,8S-epo-2me-17ene-18Hy acted synergistically with (?)-disparlure.

关键词： Asian gypsy moth Lymantria dispar Sex pheromone (+)-disparlure (7R,8S)-cis-7,8-epoxy-2methyloctadec-17ene