检索结果-南通市图书馆

Whole circumferential endoscopic submucosal dissection of superficial adenocarcinoma in long-segment Barrett's esophagus:A case report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2021年第10期13卷 1285-1292页

作者： Keiichiro Abe Kenichi Goda Akira Kanamori Tsunehiro Suzuki Akira Yamamiya Yoichi Takimoto Takahiro Arisaka Koki Hoshi Takeshi Sugaya Yuichi Majima Keiichi Tominaga Makoto Iijima Shinichi Hirooka Hidetsugu yamagishi Atsushi Irisawa Department of Gastroenterology Dokkyo Medical UniversityMibu 321-0293TochigiJapan Department of Pathology The Jikei University School of MedicineNishishimbashi 105-8471TokyoJapan Academic Institutional Research Center Dokkyo Medical UniversityMibu 321-0293TochigiJapan

BACKGROUND Esophageal adenocarcinoma(EAC)derived from long-segment Barrett’s esophagus(LSBE)is extremely rare in ***-related EAC is often difficult to diagnose in the horizontal *** the tumor has spread throughout the LSBE,whole circumferential endoscopic submucosal dissection(ESD)should be performed,which is difficult to complete ***,whole circumferential ESD can bring refractory postoperative *** hereby report a case of EAC involving the whole circumference of the LSBE,achieving complete endoscopic removal without *** SUMMARY An 85-year-old man with the chief complaint of dysphagia underwent *** suspected a flat-type cancerous lesion that extended the whole circumference of the LSBE(C 3.5,M 4.0)using narrow-band imaging magnification endoscopy(NBI-M).We achieved circumferential en bloc resection of the lesion safely with special ESD *** of the ESD specimens demonstrated that the superficial EAC extended the whole circumference of the LSBE,and papillary or well-differentiated tubular adenocarcinoma was confined in the lamina propria mucosa showing a vertical negative *** prevent post-ESD stenosis,we performed endoscopic local injection of steroids,followed by oral administration of *** was no evidence of esophageal refractory stenosis or tumor recurrence 30 mo after *** summary,we experienced a rare case of LSBE-related *** horizontal tumor extent was accurately diagnosed by ***,we achieve whole circumferential ESD safely without postoperative refractory *** NBI-M,ESD,and steroid therapy enabled the curative resection of superficial full circumferential LSBE-related EAC without refractory postoperative stenosis.

关键词： Endoscopic submucosal dissection Long-segment Barrett's esophagus Superficial esophageal adenocarcinoma Steroid Magnification endoscopy Case report

Outcomes and Prognostic Factors for Adenocarcinoma/Adenosquamous Carcinomas Treated with Radical Hysterectomy and Adjuvant Therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2014年第14期4卷 909-915页

作者： Masayuki Yamaguchi Yoko yamagishi Nobumichi Nishikawa Masayuki Sekine Takehiro Serikawa Katsunori Kashima Takayuki Enomoto Department of Obstetrics and Gynecology Graduate School of Medical and Dental Sciences Niigata University Niigata City Japan

Objective: To determine outcomes and prognostic factors for early-stage cervical adenocarcinoma/ adenosquamous carcinomas (AC/ASC) patients who are treated with radical hysterectomy and adjuvant therapy to optimize their treatment. Methods: We retrospectively reviewed the medical records of 26 patients with International Federation of Gynecologists and Obstetricians stage IB-IIB cervical AC/ASC who were treated with radical hysterectomy and adjuvant therapy. Overall survival (OS) and progression-free survival (PFS) were calculated using the Kaplan-Meier method and compared using the log-rank test. The prognostic significance of various clinical features was determined by using multivariate analysis with the Cox proportional hazards regression model. Results: Univariate analysis revealed that OS was significantly shorter in patients with lymph node metastasis and lymphovascular space invasion. Similarly, PFS was significantly shorter for patients with lymph node metastasis and parametrial invasion. Furthermore, multivariate analysis showed that lymph node metastasis was the only independent predictor for PFS (hazard ratio: 6.47, 95% confidence interval: 1.33 - 31.44, p = 0.021). However, the use of adjuvant chemoradiotherapy did not have any significant effect on either OS or PFS, regardless of lymph node metastasis. Conclusions: Lymph node metastasis is an independent prognostic factor for poor survival in cervical AC/ASC patients treated with radical hysterectomy and adjuvant therapy. In addition, adjuvant chemoradiotherapy does not improve their survival, regardless of lymph node metastasis, which suggests that novel or personalized adjuvant therapeutic strategies with fewer adverse effects than existing strategies are needed.

关键词： Adjuvant Therapy Cervical Adenocarcinoma Cervical Adenosquamous Carcinoma Lymph Node Metastasis Prognostic Factors

Clarithromycin Attenuates the Bronchial Epithelial Damage Induced by <i>Mycoplasma pneumoniae</i>Infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Microbiology 2014年第11期4卷 697-703页

作者： Hiroshi Tanaka Hisato Sadakata Tae Nagami Shun Miyazaki Tsutomu Tomita Shuhei Shirata Takehiro yamagishi NPO Sapporo Cough Asthma and Allergy Center Sapporo Japan Taishotoyama Pharmaceutical Co. Ltd. Tokyo Japan TIMELAPSE VISION Inc. Saitama Japan

To analyze the bronchial epithelial cell damage induced by Mycoplasma pneumonia and the therapeutic effects of clarithromycin, we observed bronchial tissue damage by using a mouse model and performing immunostaining and scanning electron microscopy. The immunostaining study showed that M. pneumoniae-labeled fluorescence was found on the mucosal epithelium of mice, 6 days after inoculation. Clarithromycin treatment reduced the fluorescence. In this study, we demonstrated that the morphological alterations of bronchial mucosa, including the shortening and loss of ciliavisualized by scanning electron microscopy, and the inflammatory cell migration in the submucosal tissue visualized by differential interference contrast microscopy, were induced by mycoplasmal infection. We also showed that clarithromycin treatment, when administered from the first day of inoculation, attenuated both the bronchial epithelial damage and inflammatory cell migration in the submucosal tissue. These results suggest that the therapeutic effects of clarithromycin against mycoplasmal infection, may be due to its antibacterial and anti-inflammatory activities.

关键词： Mycoplasma pneumoniae Epithelial Cell Damage Clarithromycin Murine Model

Clinical Impact of Bacteremia Due to <i>Staphylococcus saprophyticus</i>

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2021年第1期11卷 6-12页

作者： Daisuke Tamura Hiroaki Yamane Hikaru Tabakodani Hirokazu yamagishi Erika Nakazato Yumiko Kimura Masayoshi Shinjoh Takanori Yamagata Department of Pediatrics Jichi Medical University Tochigi Japan Department of Clinical laboratory Jichi Medical University Hospital Tochigi Japan Department of Pediatrics Keio University School of Medicine Tokyo Japan

Objective: This was a retrospective study to evaluate the clinical impact of bacteremia due to Staphylococcus saprophyticus and identify which factors influence it. Methods: We reviewed all patients with bacteremia due to S. saprophyticus over the last 12 years. This study was performed at Jichi Medical University Hospital in Japan, a key hospital in the northern Kanto area including Tochigi, Gunma, Ibagagi, and northern Saitama prefectures. We retrospectively reviewed the blood culture results and medical records of all patients with a history of visits or hospitalizations between April 2008 and September 2020. Results: During the study period, 4 blood culture specimens were considered to have S. saprophyticus bacteremia. Two of these were from subjects > 60 years old who had severe infection. A third case, 27 years old, was thought to have a catheter-related bloodstream infection;however, the only symptom was fever, which was not serious. The fourth case, a previously unreported pediatric patient, had non-severe fever. The mean time for a diagnosis of bacteremia by blood culture testing was 42 hours, whereas contamination appeared in cultures after another 50 hours. Conclusion: The pathogenicity of S. saprophyticus might be lower in the blood than in the urine due to its physiological function and activity. In older adults with underlying diseases, the severity of bacteremia was more pronounced, whereas in a young adult and a child, the disease was relatively mild. Age and underlying disease might be useful factors to consider when diagnosing bacteremia due to S. saprophyticus.

关键词： Gram-Positive Staphylococcus Coagulase-Negative Staphylococcus Staphylococcus saprophyticus Bacteremia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

管状住宅

设计 2012年第10期25卷 I0058-I0059页

作者： Jacob Takeshi yamagishi(图)

这是位于日本名古屋的一处街边住宅，场地的宽度为5米，与大门前面的街道一样宽，而进入室内后，室内空间最窄处呈3米宽的管状。这个管状空间分成两个分支，一个分支悬在空中创建出用于停车的空隙，另一个稍微向下移动形成入口空间。这... 详细信息

这是位于日本名古屋的一处街边住宅，场地的宽度为5米，与大门前面的街道一样宽，而进入室内后，室内空间最窄处呈3米宽的管状。这个管状空间分成两个分支，一个分支悬在空中创建出用于停车的空隙，另一个稍微向下移动形成入口空间。这个22米长的入口空间并不是封闭的走廊，而更像一条开敞的街道，两边都与外界相通，甚至有一个分支和分岔点，更像是一条带有天花板的小巷，这条小巷引导人们从场地的一边走向另一边，另一边有一个小花园和一条小溪绿廊。

关键词：管状住宅室内空间入口空间名古屋分岔点天花板场地

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

东京浅草的新视野

缤纷 2013年第5期 20-21页

作者： Kengo Kuma Takeshi yamagishi

说到东京的浅草寺,巨大的"雷门"红灯笼几乎是所有人对此地的第一印象。现在,在东京浅草寺地区,一座新的文化建筑成为了这里不得不说的地标——浅草文化观光中心。这个采用了日本传统建筑中"木"的表达又叠加了当代建筑体积感的观光中心,... 详细信息

说到东京的浅草寺,巨大的"雷门"红灯笼几乎是所有人对此地的第一印象。现在,在东京浅草寺地区,一座新的文化建筑成为了这里不得不说的地标——浅草文化观光中心。这个采用了日本传统建筑中"木"的表达又叠加了当代建筑体积感的观光中心,是建筑师隈研吾的新作,也代表了当代日本风格建筑的典型。浅草寺地区的街道拥挤而复杂。

关键词：逐层递进当代日本中心基地体积感繁华热闹红灯笼雷门垂直化日本传统光中心

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

十字花科蔬菜抗病性筛选技术

植物医学 1987年第2期 42-44页

作者： Hiroshi yamagishi 陈剑平

十字花科作物对人类有非常重要的用途,它们不仅是全世界性蔬菜作物,还是油料和饲料作物。在日本,十字花科作物,尤其是萝卜、白菜和甘蓝是最重要的蔬菜,占1983年日本蔬菜栽培总面积和总产量的25％和36％。在育种工作中,抗病性筛选是必不... 详细信息

十字花科作物对人类有非常重要的用途,它们不仅是全世界性蔬菜作物,还是油料和饲料作物。在日本,十字花科作物,尤其是萝卜、白菜和甘蓝是最重要的蔬菜,占1983年日本蔬菜栽培总面积和总产量的25％和36％。在育种工作中,抗病性筛选是必不可少的。这不论对寻找抗病材料还是对子代选择都是必要的。本文将提供已经确立的或目前

关键词：十字花科蔬菜抗病性

Is Dose Adjustment Based on Several Factors of Body Size Descriptors Effective for Prevention of Thrombocytopenia by Linezolid Therapy in Hemodialysis Patients?

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2016年第10期7卷 417-423页

作者： Hideo Kato Mao Hagihara Yuka yamagishi Yukihiro Hamada Jun Hirai Naoya Nishiyama Yusuke Koizumi Katsuhiko Matsuura Hiroshige Mikamo Department of Infection Control and Prevention Aichi Medical University School of Medicine Nagakute Japan Department of Pharmacy Aichi Medical University School of Medicine Nagakute Japan

Previous study suggested that low body weight was one of the risk factors of thrombocytopenia induced by linezolid in non-hemodialysis patients. However, there have been little investigations for the linezolid-induced thrombocytopenia in hemodialysis patients. This study was to evaluate the association between several factors of body size descriptors and thrombocytopenia in hemodialysis-patients. No factor of body size descriptors showed significant correlation with linezolid-induced thrombocytopenia (patients with thrombocytopenia vs patients without thrombocytopenia: body weight;60.0 kg vs 55.3 kg, p = 0.82: body mass indices;21.1 kg/m2 vs 21.2 mg/m2, p = 0.44: ideal body weight;61.2 kg vs 59.5 kg, p = 0.21: lean body weight;50.1 kg vs 45.7 kg, p = 0.64: dosage amount;20.0 mg/kg vs 21.7 mg/kg, p = 0.74: body surface area;1.65 m2 vs 1.54 m2, p = 0.43). There were not significant differences in the body size descriptors between linezolid therapy for more than 14 days and for less than 13 days (more than 14 days vs less than 13 days: body weight;53.5 kg vs 56.8 kg, p = 0.75: body mass indices;20.9 kg/m2 vs 21.1 mg/m2, p = 0.47: ideal body weight;60.3 kg vs 59.9 kg, p = 0.17: lean body weight;44.3 kg vs 47.7 kg, p = 0.56: dosage amount;22.4 mg/kg vs 21.1 mg/kg, p = 0.67: body surface area;1.51 m2 vs 1.59 m2, p = 0.37). Our data suggested that dosage adjustment of linezolid based on body weight was not recommended in hemodialysis-patients.

关键词： Linezolid Thrombocytopenia Body Weight

美日医学科学协作规划第二十二次联合学术讨论会——来自胆囊炎患者的未定名弧菌的一些特性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

微生物学免疫学译刊 1988年第2期 30-31页

作者： Takayoshi yamagishi 袁佩娜

我们从一名75岁慢性胆囊炎女性患者的胆汁中发现了嗜盐性弧菌,并保存了两株菌种。这两株菌分别在持续两个月内的两个日期得到的,暂命名为Otake Ⅰ和Otake Ⅱ;并与弧菌属的六种菌即创伤弧菌、付溶血弧菌、溶藻弧菌、鳗弧菌、Ordalli弧菌... 详细信息

我们从一名75岁慢性胆囊炎女性患者的胆汁中发现了嗜盐性弧菌,并保存了两株菌种。这两株菌分别在持续两个月内的两个日期得到的,暂命名为Otake Ⅰ和Otake Ⅱ;并与弧菌属的六种菌即创伤弧菌、付溶血弧菌、溶藻弧菌、鳗弧菌、Ordalli弧菌和霍乱弧菌的10个参考菌株进行特性比较。

关键词：弧菌属菌种鳗弧菌溶藻弧菌创伤弧菌嗜盐性