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Small Angle X-Ray Scattering Imaging of Soft Tissue by Using Laue Diffraction Optical System

Open Journal of Medical Imaging 2018年第3期8卷 54-63页

作者： Ge Jin Kenichi Okamura Yoshifumi Suzuki Yong Sun yoshinori chikaura Masami Ando Department of Applied Science for Integrated System Engineering Kyushu Institute of Technology Kitakyushu Japan Research Institute for Science and Technology Tokyo University of Science Noda Japan

We performed a feasibility study of Small angle X-ray scattering imaging under the condition of X-ray bright field imaging by Laue crystal diffraction optics of X-ray dark-field imaging that works as an angular analysis. Collagen in chicken tibia containing abundant soft fibrous tissue was chosen as a specimen. In traditional Small angle X-ray scattering optical system, we can derive the structure information of sample by calculating q value which is available from a scattering pattern. Thus it is usually necessary to conduct a 2D scan in order to obtain scattering image. In this paper it is described by a method by which not only small angle X-ray scattering imaging is available directly but also bright-field imaging and dark-field imaging can be obtained at the same time. As the first step, the feasibility of the imaging method should be confirmed by taking pictures of the samples with known periodic length. The preliminary test showed that the collgan’s lattice spacing d is 65.1 nm that was also taken photos by scanning electron microscopy. By rotating Laue angular analyzer by 112 arcseconds small angle X-ray scattering image appeared in bright-field.

关键词： XDFI SAXS Synchrotron Radiation Soft Tissue

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