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Small invasive colon cancer with adenoma observed by endocytoscopy: A case report

World Journal of Gastrointestinal Endoscopy 2020年第9期12卷 304-309页

作者： yoshika akimoto Shin-ei Kudo Katsuro Ichimasa Yuta Kouyama Masashi Misawa Tomokazu Hisayuki Toyoki Kudo Tetsuo Nemoto Digestive Disease Center Showa University Northern Yokohama HospitalYokohama 224-8503Japan Department of Pathology Showa University Northern Yokohama HospitalYokohama 224-8503Japan

Endocytoscopy is a next-generation endoscopic system that facilitates real-time histopathologic endoscopic diagnosis of colorectal lesions by virtue of its 520×maximum *** SUMMARY We present the case of a 63-year-old man with sigmoid colon cancer who was regularly referred for follow-up colonoscopy after endoscopic resection of T1 rectal *** revealed a 12 mm reddish polyp,including a depression and a flat area in the sigmoid *** observation showed unclear gland formation and agglomeration of distorted nuclei(depression),suggesting a submucosal invasive(T1)*** the flat area,slitlike smooth lumens and regular pattern of fusiform nuclei were found,suggesting an *** the basis of these endocytoscopic findings,we predicted this lesion as T1 cancer(depression)with adenoma(flat area)and performed endoscopic resection corresponding to the final histopathological *** We could perform an optical diagnosis of T1 sigmoid cancer with adenoma by using endocytoscopy before treatment.

关键词： Endocytoscopy T1 colorectal cancer Adenoma Optical diagnosis Case report

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Clinicopathological features of small T1 colorectal cancers

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World Journal of Clinical Cases 2021年第33期9卷 10088-10097页

作者： Yuki Takashina Shin-Ei Kudo Katsuro Ichimasa Yuta Kouyama Kenichi Mochizuki yoshika akimoto Yasuharu Maeda Yuichi Mori Masashi Misawa Noriyuki Ogata Toyoki Kudo Tomokazu Hisayuki Takemasa Hayashi Kunihiko Wakamura Naruhiko Sawada Toshiyuki Baba Fumio Ishida Kazunori Yokoyama Mitsuru Daita Tetsuo Nemoto Hideyuki Miyachi Digestive Disease Center Showa University Northern Yokohama HospitalYokohama 224-8503Japan Department of Gastroenterology Nikko Kinen HospitalMuroran 051-8501Japan Clinical Effectiveness Research Group Institute of Health and SocietyUniversity of OsloOslo 0001Norway Department of Pathology Showa University Nothern Yokohama HospitalYokohama 224-8503Japan

BACKGROUND Although small colorectal neoplasms(<10 mm)are often easily resected endoscopically and are considered to have less malignant potential compared with large neoplasms(≥10 mm),some are invasive to the *** To clarify the clinicopathological features of small T1 colorectal *** Of 32025 colorectal lesions between April 2001 and March 2018,a total of 1152 T1 colorectal cancers resected endoscopically or surgically were included in this study and were divided into two groups by tumor size:a small group(<10 mm)and a large group(≥10 mm).We compared clinicopathological factors including lymph node metastasis(LNM)between the two *** The incidence of small T1 cancers was 10.1%(116/1152).The percentage of initial endoscopic treatment in small group was significantly higher than in large group(<10 mm 74.1%vs≥10 mm 60.2%,P<0.01).In the surgical resection cohort(n=798),the rate of LNM did not significantly differ between the two groups(small 12.3%vs large 10.9%,P=0.70).In addition,there were also no significant differences between the two groups in pathological factors such as histological grade,vascular invasion,or lymphatic *** Because there was no significant difference in the rate of LNM between small and large T1 colorectal cancers,the requirement for additional surgical resection should be determined according to pathological findings,regardless of tumor size.

关键词： Colorectal neoplasms Lymphatic metastasis Biological phenomena Polyps Colorectal cancers

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