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Fabrication of Mie-resonant silicon nanoparticles using laser annealing for surface-enhanced fluorescence spectroscopy

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Microsystems & Nanoengineering 2024年第2期10卷 133-141页

作者： Tatsuya Fukuta Ryo Kato Takuo Tanaka Taka-aki yano Institute of Post-LED Photonics Tokushima University2-1 Minami-JosanjimaTokushima770-8506Japan Innovative Photon Manipulation Research Team RIKEN Center for Advanced PhotonicsWakoSaitama351-0198Japan Metamaterials Laboratory RIKEN Cluster for Pioneering ResearchWakoSaitama351-0109Japan

Silicon nanostructures with unique Mie resonances have garnered considerable attention in the field of ***,we present a simple and efficient method for the fabrication of silicon(Si)nanoparticle substrates using continuous-wave(CW)laser *** resulting silicon nanoparticles exhibit Mie resonances in the visible region,and their resonant wavelengths can be precisely ***,laser-annealed silicon nanoparticle substrates show a 60-fold enhancement in *** tunable and fluorescence-enhancing silicon nanoparticle platform has tremendous potential for highly sensitive fluorescence sensing and biomedical imaging applications.

关键词： nanoparticles annealing resonant

An Application of Sailing Data Acquisition and Transfer System to Supporting System for Ship Handling in Harbour——System Development on T.S. Fukae-maru

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An Application of Sailing Data Acquisition and Transfer Syst...

Historical Improvement of Legal Systems of Safety and Health for Mariners in Japan

2002年中、日、韩航海学术交流会

作者： Nobukazu WAKABAYASHI yoshiji yano Kobe University of Mercantile Marine 5-1-1 Fukaeminami-machi Higashinada-ku Kobe JAPAN Kobe University of Mercantile Marine 5-1-1 Fukaeminami-machi Higashinada-ku Kobe JAPAN

The FDDI network of 100 Mbps has been installed on the Training Ship Fukae-maru. The ship LAN has been equipped with the various sensors by which it is possible to collect the sailing data through the sequencer. The authors have proposed a system to transfer the sailing data, which were measured with the sensors using this feature, and to utilize these data via the LAN system. The data include many items such as the heading, speed, the position by the D-GPS (Differential GPS), the rudder angle, *** this paper, it is explained that how the system works to support docking and undocking the berth. The system can estimate the situation of the ship in the near future to advance from the heading and the D-GPS position which is obtained by the sailing data acquisition and transfer system, and it displays estimated position and heading by the graphics. Because the captain handling a ship can imagine the change of the ship's motion easily, our system is useful to inform the captain the appropriate updated manoeuvring data in *** introduce the technique to estimate the ship's motion in the near future simply by extrapolation using the least squares approximation from the data in the past. The method is simple and fast to calculate. The system displays both, the past and the estimated data as two-dimensional graphics in the window of the laptop PC. The display is updated every second.

关键词： Ship handling in harbour, Ship LAN, Estimation of ship's motion, Sailing data acquisition and transfer system

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Historical Improvement of Legal Systems of Safety and Health...

Effects of elafibranor on liver fibrosis and gut barrier function in a mouse model of alcohol-associated liver disease

Asia Navigation Conference 2009

作者： Keiji SASAYA Masao FURUSHO yoshiji yano Toyama National College of Maritime Technology Graduate School of Maritime Sciences Kobe University 1-2 EbieNeriyaImizu city Toyama Prefecture

＜正＞*** Whether it is labor at sea or on land,the protection of the life,body,and health of workers is more important than anything *** number of Japanese mariners or seafarers working at sea in Japan is 74,618（2007）,a number that is extremely small compared to the total working population of approximately 63,000,000 workers（2007）.The ratio of accidents involving mariners（occupational accidents causing absences of more than four days）,however,is consistently higher when compared with occupational accidents on land（See Fig.1 and Fig.2）.

关键词： Safety and Health Mariner’s accident Mariners Law

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World Journal of Gastroenterology 2024年第28期30卷 3428-3446页

作者： Aritoshi Koizumi Kosuke Kaji Norihisa Nishimura Shohei Asada Takuya Matsuda Misako Tanaka Nobuyuki Yorioka Yuki Tsuji Koh Kitagawa Shinya Sato Tadashi Namisaki Takemi Akahane Hitoshi yoshiji Department of Gastroenterology Nara Medical UniversityKashihara 634-8521Japan

BACKGROUND Alcohol-associated liver disease(ALD)is a leading cause of liver-related morbidity and mortality,but there are no therapeutic targets and modalities to prevent ALD-related liver *** proliferator activated receptor(PPAR)α and δ play a key role in lipid metabolism and intestinal barrier homeostasis,which are major contributors to the pathological progression of ***,elafibranor(EFN),which is a dual PPARαand PPARδagonist,has reached a phase III clinical trial for the treatment of metabolic dysfunctionassociated steatotic liver disease and primary biliary ***,the benefits of EFN for ALD treatment is *** To evaluate the inhibitory effects of EFN on liver fibrosis and gut-intestinal barrier dysfunction in an ALD mouse *** ALD-related liver fibrosis was induced in female C57BL/6J mice by feeding a 2.5% ethanol(EtOH)-containing Lieber-DeCarli liquid diet and intraperitoneally injecting carbon tetrachloride thrice weekly(1 mL/kg)for 8 ***(3 and 10 mg/kg/day)was orally administered during the experimental *** and molecular analyses were performed to assess the effect of EFN on steatohepatitis,fibrosis,and intestinal barrier *** EFN effects on HepG2 lipotoxicity and Caco-2 barrier function were evaluated by cell-based *** The hepatic steatosis,apoptosis,and fibrosis in the ALD mice model were significantly attenuated by EFN *** promoted lipolysis and β-oxidation and enhanced autophagic and antioxidant capacities in EtOH-stimulated HepG2 cells,primarily through PPARα***,EFN inhibited the Kupffer cell-mediated inflammatory response,with blunted hepatic exposure to lipopolysaccharide(LPS)and toll like receptor 4(TLR4)/nuclear factor kappa B(NF-κB)*** improved intestinal hyperpermeability by restoring tight junction proteins and autophagy and by inhibiting apoptosis and proinflammatory *** protective effect on intestinal bar

关键词： Liver fibrosis Ethanol Gut barrier function Apoptosis Autophagy Peroxisome proliferator activated receptor

Correlation between dose-volume parameters and rectal bleeding after 12 fractions of carbon ion radiotherapy for prostate cancer

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World Journal of Radiology 2024年第7期16卷 256-264页

作者： Takashi Ono Hiraku Sato Yuya Miyasaka Yasuhito Hagiwara Natsuko yano Hiroko Akamatsu Mayumi Harada Mayumi Ichikawa Department of Radiation Oncology Faculty of MedicineYamagata UniversityYamagata 990-9585Japan Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical ScienceYamagata 990-9585Japan

BACKGROUND Carbon ion radiotherapy(CIRT)is currently used to treat prostate *** bleeding is a major cause of toxicity even with ***,to date,a correlation between the dose and volume parameters of the 12 fractions of CIRT for prostate cancer and rectal bleeding has not been ***,the clinical risk factors for rectal bleeding were absent after 12 fractions of *** To identify the risk factors for rectal bleeding in 12 fractions of CIRT for prostate *** Among 259 patients who received 51.6 Gy[relative biological effectiveness(RBE)],in 12 fractions of CIRT,15 had grade 1(5.8%)and nine had grade 2 rectal bleeding(3.5%).The dose-volume parameters included the volume(cc)of the rectum irradiated with at least x Gy(RBE)(Vx)and the minimum dose in the most irradiated x cc normal rectal volume(Dx).RESULTS The mean values of D6cc,D2cc,V10 Gy(RBE),V20 Gy(RBE),V30 Gy(RBE),and V40 Gy(RBE)were significantly higher in the patients with rectal bleeding than in those *** cutoff values were D6cc=34.34 Gy(RBE),D2cc=46.46 Gy(RBE),V10 Gy(RBE)=9.85 cc,V20 Gy(RBE)=7.00 cc,V30 Gy(RBE)=6.91 cc,and V40 Gy(RBE)=4.26 *** D2cc,V10 Gy(RBE),and V20 Gy(RBE)cutoff values were significant predictors of grade 2 rectal *** The above dose-volume parameters may serve as guidelines for preventing rectal bleeding after 12 fractions of CIRT for prostate cancer.

关键词： Carbon ion radiotherapy Prostate cancer Rectal bleeding Dose volume parameters Prevention

Effect of Intertidal Elevation at Tsuyazaki Cove,Fukuoka,Japan on Survival Rate of Horseshoe Crab Tachypleus tridentatus Eggs

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Journal of Ocean University of China 2022年第3期21卷 601-610页

作者： ITAYA Shinji SHUUNO Mari ONIKURA Norio TAI Akira yano Shinichiro Environmental Fluid Dynamics Laboratory Department of Urban and Environmental EngineeringGraduate School of EngineeringKyushu UniversityFukuoka819-0395Japan Tsuyazaki Seaside Nature School Fukutsu811-3304Japan Fishery Research Laboratory Department of Bioresource ScienceGraduate School of Bioenvironmental ScienceKyushu UniversityFukuoka819-0395Japan

Physical factors affecting the survival of Tachypleus tridentatus eggs were investigated by translocating their eggs between the high intertidal zone and the low intertidal zone of a known spawning *** mean egg survival rates per day were highest in the mid intertidal zone(45.1%±25.4%)and the lowest in the low intertidal zone(13.3%±27.6%).Differences in the elevation,air exposure time,and water content of the spawning ground were significant factors determining the egg survival *** or insufficient air exposure time resulted in inadequate water content at higher and lower intertidal zones and could reduce egg *** the other hand,moderate saturation and dehydration were repeated with each tidal movement in the mid intertidal *** dynamic is considered as one of the crucial factors for the survival of eggs and is considered optimal for ***,the protection of the mid intertidal zone is imperative for maximizing the egg survival rate in Tsuyazaki Cove where almost all suitable nesting sites have disappeared due to coastal *** protecting these optimal sites for spawning and recovering other optimal sites on suitable beaches,a positive contribution can be made to future management and *** study also suggests that translocating eggs from marginal to optimal spawning sites might be a recovery strategy for this globally endangered species.

关键词： air exposure time globally endangered species intertidal elevation intertidal zone optimal spawning site Tachypleus tridentatus translocated horseshoe crab eggs Tsuyazaki Cove

Crowd evacuation of pairs of pedestrians

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Communications in Theoretical Physics 2022年第4期74卷 97-112页

作者： Ryosuke yano Tokio Marine d R Co.ltd. 1-5-1OtemachiChiyoda-kuTokyo100-0004Japan

The crowd evacuation of pairs of pedestrians(*** consisting of a parent and a child)is numerically ***,it is assumed that all pedestrians have their own partners,and move randomly inside the bounded domain of the right-hand room as an initial *** pedestrians start their evacuations after they contact their *** evacuations are completed by the transfer of all the pairs from the right-hand room to the left-hand room through an exit.A frozen swarm tends to appear in the right-hand room as the total number of pedestrians *** frozen swarm moves without changing its form,unless it is dissolved by a strong collision with a pair of pedestrians that comes back from the left-hand room by ***,the evacuation speed also depends on the area of the Escape Zone,whereas an obstacle placed in front of an exit also changes the speed of the evacuation in accordance with the type of motion of the children.

关键词： Evacuation of paired pedestrians force chain network escape from crowd

Ongoing Applicative Studies of Plant Thioredoxins

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Molecular Plant 2014年第1期7卷 4-13页

作者： Hiroyuki yano National Food Research Institute National Agriculture and Food Research Organization Kannondai 2-1-12 Tsukuba Ibaraki 305-8642 Japan

Studies triggered by the discovery of the function of thioredoxin （Trx） in photosynthesis have revealed its role throughout biology. Parallel biochemical and proteomic analyses have led to the identification of its numerous puta- tive targets. Recently, to verify the biological significance of these targets, in vivo studies using transformants in which Trx is overexpressed or suppressed are in progress, and the transformants themselves that are being used in such studies show their potential applicative values. Moreover, Trx＇s mitigation of allergenicity for some proteins offers promising prospects in the food industry. Practical studies based on redox regulation, once only on the horizon, are now achieving new dimensions. This short review focuses on the industrial applications of Trx studies, the current situation, and future perspectives. The putative targets obtained by the proteomics approach in comparison with in vivo observations of the transformants are also examined. Applicative studies of glutathione, a counterpart of Trx, are also discussed briefly.

关键词： allergen food redox regulation target thioredoxin.

INTELLIGENT METATAL COMPLEXES CONTAINING N-GLYCOSIDES FORMED FROM TRIS (2-AMINOETHYL) AMINE AND ALDOSES, HAVING MOLECULAR RECOGNITION ABILITY

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Chinese Journal of Polymer Science 1998年第3期16卷 193-206页

作者： yano Shigenobu Department of Chemistry Nara Women's University Kitauoyanishimachi Nara 630-8263 Japan

Assembly of carbohydrates on nickel (Ⅱ) center by utilizing N-glycosidicbond formation with a branched amine: tris(2-aminoethyl)amine (tren), an unprecedentedchiral inversion around the metal center (Co or Mn) induced by an interaction betweensugars and sulfate anions, peroxo-bridged dinuclear cobalt (Ⅲ) complex containing N-glycoside ligands from tren and D-glucose and its reversible dioxygen binding property,and novel trimanganese complexes with a linear Mn_3 (Ⅱ, Ⅲ, Ⅱ) assemblage bridged bycarbohydrates are described.

关键词： Intelligent sugar complex Molecular recognition N-glycoside complex