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基于多航天器测量数据的空间磁流体动力学分析

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基于多航天器测量数据的空间磁流体动力学分析

作者：西村仁宏（yoshihiro nishimura）上海交通大学

学位级别：硕士

大幅度磁流体动力学(MHD)波和湍流通常在空间等离子体环境中观察到。使用通过多航天器实验获得的数据,可以分离测量变量的时间和空间变化。虽然时域中的数据点的数量可能会相当大,但是在空间域中,其仅仅是航天器的数量,至多只有几个。因... 详细信息

大幅度磁流体动力学(MHD)波和湍流通常在空间等离子体环境中观察到。使用通过多航天器实验获得的数据,可以分离测量变量的时间和空间变化。虽然时域中的数据点的数量可能会相当大,但是在空间域中,其仅仅是航天器的数量,至多只有几个。因此,诸如Capon方法的复杂技术经常用于处理数据。由于湍流包含大量的波,因此实际上不可能使用观测数据来分解它。然而,在湍流分析中,我们感兴趣的不是将湍流分离成所有单个波,而是确定描述湍流性质的几个宏观物理参数。在本论文中,我们讨论了当只有有限数量的数据点可用时,在给定的测试湍流谱上提取尽可能多的信息的方法。给出测试湍流的波幅,使得湍流谱遵守具有指定总功率和功率定律指数的幂律分布。通过改变数据点的数量,数据点的空间分离,事件的数量和其他外部参数来检查我们的分析方法的准确性和鲁棒性。在参数调查之后,我们发现波模式的数量,x轴,数据点和事件的分离,相位相关的指数,数据点的空间间隔是影响Capon估计的重要参数。在获得需要使用的值之后,可以通过Capon方法并使用那些值获得测试湍流的宏观参数。为了建立分析空间等离子体湍流的新方法,我们能够开发出产生可靠的幂律指数的计算程序。我们应用这种方法分析几个航天器在空间等离子体获得的真实湍流数据,精度能够达到1英寸以内。

关键词：湍流 Capon方法空间等离子体

Early diagnosis of health damage in arc welders based on their serum ferritin level

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The Effect of Umami Stimulation on Salivary Secretion Rate and Duration

Open Journal of Internal Medicine（内科学期刊） 2011年第3期

作者： Kazuaki Sera yoshihiro nishimura Chiyo Hayashi Hisahide Nishio

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Health 2024年第1期16卷 52-59页

作者： Eri Sambuichi Rumi nishimura Shiho Morishita Shigeru Watanabe Department of Oral Health Sciences School of Health Sciences Meikai University Urayasu Japan Department of Oral Epidemiology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan

Purpose: Umami reportedly promotes salivation. We aimed to investigate the effects of taste stimuli on slow and fast salivary secretion in humans using umami, sweet, and sour stimuli. Methods: Eight healthy women participated between 14:00 and 15:00, taking the circadian rhythm of salivary secretion into account. The types and concentrations of the taste solutions were glutamic acid (1.7 × 10−3 M), inosinic acid (9.8 × 10−3 M), and guanylic acid (9.8 × 10−3 M) for umami stimulation, citric acid (6.5 × 10−3 M) for acidity stimulation, and sucrose (1.6 × 10−2 M) for sweetness stimulation. First, the unstimulated salivary flow rate was measured. Then, 3 ml of a flavor solution was dropped under the tongue using a syringe. The saliva was expelled into an aluminum cup every minute and weighed. The first minute’s value minus 3 ml flavor solution was the stimulated salivary secretion rate produced by each flavor. The time-to-return to the initial unstimulated salivary flow rate was the duration of the stimulated saliva secretion rate. Results: The mean unstimulated salivary flow rate across participants was 0.64 ± 0.25 ml/min (range: 0.23 - 1.03 ml/min). The highest amount of saliva was induced by citric acid. There were significant differences between citric acid and the other flavor solutions (p < 0.05 for glutamic acid, inosinic acid, and sucrose;p < 0.01 for guanylic acid). There were no significant differences in duration of salivation between the flavor solutions. When the participants were divided into slow (0.45 ± 0.16 ml/min) and fast groups (0.83 ± 0.15 ml/min) based on their median resting salivary secretion rate, there were no significant differences between the two groups in the amount of saliva secreted at 1 minute after stimulation and the duration of the salivary secretion rate. Conclusion: Umami stimulation was effective in slowing salivary secretion and sustaining salivary secretion after stimulation.

关键词： Salivary Secretion Umami Flavor Oral Health Stimulated Salivary Secretion

Rare incidence of mucosa-associated lymphoid tissue lymphoma presenting as buccal fat pad tumor:A case report

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World Journal of Clinical Cases 2024年第31期12卷 6506-6512页

作者： Keitaro Miyake Kazuhiro Hirasawa Haruka nishimura Kiyoaki Tsukahara Department of Otolaryngology Head and Neck SurgeryTodachuo General HospitalToda-shi 335-0023SaitamaJapan Department of Otorhinolaryngology Head and Neck SurgeryTokyo Medical University HospitalShinjuku-ku 160-0023Japan

BACKGROUND Mucosa-associated lymphoid tissue(MALT)lymphoma,a type of non-Hodgkin lymphoma,originates in the mucosal lining of body organs and internal cavities,including the nose,mouth,lungs,and digestive *** lymphoma develops when the body produces abnormal B *** lymphomas develop at the edge of the lymphoid tissue,called the marginal zone,and,hence,are classified as a type of marginal zone *** are the most common type of marginal zone lymphomas although their occurrence is *** date,no previous cases of MALT lymphoma in the buccal fat pad have been *** SUMMARY We report the case of a patient who presented with a mass on the frontal *** resonance imaging revealed a tumor in the buccal fat pad,and histopathological and immunohistochemical findings confirmed the diagnosis of MALT *** patient had a history of Helicobacter pylori and hepatitis C virus infection,suggesting an association between these infective agents and MALT *** Consideration of MALT lymphoma is essential in the differential diagnosis of frontal cheek masses.

关键词： Mucosa-associated lymphoid tissue lymphoma Extra gastric mucosaassociated lymphoid tissue lymphoma Plain computed tomography Helicobacter pylori Case report

Effects of elafibranor on liver fibrosis and gut barrier function in a mouse model of alcohol-associated liver disease

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World Journal of Gastroenterology 2024年第28期30卷 3428-3446页

作者： Aritoshi Koizumi Kosuke Kaji Norihisa nishimura Shohei Asada Takuya Matsuda Misako Tanaka Nobuyuki Yorioka Yuki Tsuji Koh Kitagawa Shinya Sato Tadashi Namisaki Takemi Akahane Hitoshi Yoshiji Department of Gastroenterology Nara Medical UniversityKashihara 634-8521Japan

BACKGROUND Alcohol-associated liver disease(ALD)is a leading cause of liver-related morbidity and mortality,but there are no therapeutic targets and modalities to prevent ALD-related liver *** proliferator activated receptor(PPAR)α and δ play a key role in lipid metabolism and intestinal barrier homeostasis,which are major contributors to the pathological progression of ***,elafibranor(EFN),which is a dual PPARαand PPARδagonist,has reached a phase III clinical trial for the treatment of metabolic dysfunctionassociated steatotic liver disease and primary biliary ***,the benefits of EFN for ALD treatment is *** To evaluate the inhibitory effects of EFN on liver fibrosis and gut-intestinal barrier dysfunction in an ALD mouse *** ALD-related liver fibrosis was induced in female C57BL/6J mice by feeding a 2.5% ethanol(EtOH)-containing Lieber-DeCarli liquid diet and intraperitoneally injecting carbon tetrachloride thrice weekly(1 mL/kg)for 8 ***(3 and 10 mg/kg/day)was orally administered during the experimental *** and molecular analyses were performed to assess the effect of EFN on steatohepatitis,fibrosis,and intestinal barrier *** EFN effects on HepG2 lipotoxicity and Caco-2 barrier function were evaluated by cell-based *** The hepatic steatosis,apoptosis,and fibrosis in the ALD mice model were significantly attenuated by EFN *** promoted lipolysis and β-oxidation and enhanced autophagic and antioxidant capacities in EtOH-stimulated HepG2 cells,primarily through PPARα***,EFN inhibited the Kupffer cell-mediated inflammatory response,with blunted hepatic exposure to lipopolysaccharide(LPS)and toll like receptor 4(TLR4)/nuclear factor kappa B(NF-κB)*** improved intestinal hyperpermeability by restoring tight junction proteins and autophagy and by inhibiting apoptosis and proinflammatory *** protective effect on intestinal bar

关键词： Liver fibrosis Ethanol Gut barrier function Apoptosis Autophagy Peroxisome proliferator activated receptor

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小拜登离席

财新周刊 2024年第3期 12-13页

作者： Kent nishimura(图) 无不详视觉中国

当地时间2024年1月10日,美国首部华盛顿,美国总统拜登的儿子亨特·拜登(中)在国会听证会上露面,当时众议院共和党人正准备提出决议定其藐视国会,亨特一行人突然离场。当日,经过6小时的听证会后,委员会23名成员投票支持该决议、14名成员... 详细信息

当地时间2024年1月10日,美国首部华盛顿,美国总统拜登的儿子亨特·拜登(中)在国会听证会上露面,当时众议院共和党人正准备提出决议定其藐视国会,亨特一行人突然离场。当日,经过6小时的听证会后,委员会23名成员投票支持该决议、14名成员反对。众议院将就此事进行全体投票,并可能对亨特·拜登提出进一步的刑事诉讼。

关键词：众议院共和党人听证会刑事诉讼国会亨特投票决议

Conditions of Non-Unique Identifiers in Record Linkage Using Japanese Cohort Dataset

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Journal of Data Analysis and Information Processing 2015年第4期3卷 103-111页

作者： Michikazu Nakai Kunihiro nishimura yoshihiro Miyamoto Department of Statistics and Data Analysis Center for Cerebral and Cardiovascular Disease Information National Cerebral and Cardiovascular Center Suita Japan Department of Preventive Cardiology National Cerebral and Cardiovascular Center Suita Japan

The applications of unique identifiers such as name, home address and social security number to link different datasets have been commonly used and well-published. Also, the theoretical concepts of probabilistic algorithm in record linkage have been well-defined in the literature. However, few studies have reported the applications of its probabilistic algorithm using non-unique identifiers. In this paper, we investigate several variables (weight, height, waist, age, sex, smoking and alcohol habit) as non-unique identifiers using Japanese cohort dataset with three-year baseline of 1989-1991 to observe how effectively these identifiers can be used and what influence those may have on record linkage. Moreover, we modify the conditions of these identifiers and estimate the sensitivity, specificity and accuracy for comparison. We further investigate this by using extended ten-year baseline of 1989-1999 as well. As a result, we conclude that the combination of age, sex, weight and height predicts better estimation with regards to the sensitivity, specificity and accuracy than other combinations in both men and women in case of using three-year baseline, whereas the combination of age, sex and height predicts better in both men and women in case of using ten-year baseline.

关键词： Record Linkage Probabilistic Algorithm Identifiers Epidemiology Japanese Cohort

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太赫兹行波管用金刚石输能窗研究进展

材料导报 2024年第16期38卷 20-28页

作者：张鹏伟宋惠白慧萍易剑江南西村一仁云南大学材料与能源学院昆明650091 中国科学院宁波材料技术与工程研究所浙江宁波315201

太赫兹波处于电磁波谱中电子学与光子学之间的空隙区域,具有不同于低频微波和高频光学的独特属性,在无线通信、生物医学、公共安全等军事和民用领域具有广阔的应用前景。太赫兹技术重点是对太赫兹波的产生和传输进行研究,当前所面临问... 详细信息

太赫兹波处于电磁波谱中电子学与光子学之间的空隙区域,具有不同于低频微波和高频光学的独特属性,在无线通信、生物医学、公共安全等军事和民用领域具有广阔的应用前景。太赫兹技术重点是对太赫兹波的产生和传输进行研究,当前所面临问题是在不产生额外传输损耗下保证高效率传输太赫兹信号。太赫兹行波管输能窗是典型的结构与功能一体化器件,主要起着行波管内外信号传递的作用,同时要保证器件内部的真空度以及对太赫兹波表现出高度“透明”。本文通过对近年来的文献进行总结整理,综述了国内外太赫兹行波管的应用和研究进展,揭示了未来发展大功率、高效率和宽频带传输是实现太赫兹真空器件实际应用的重点,这将对输能窗材料本身以及超精密加工提出了巨大挑战。纵观近几年国内外输能窗材料的发展历程,笔者们认为,与传统输能窗材料相比,单晶金刚石强度高,导热好,微波损耗小,没有晶界,气密性好,是最理想的太赫兹行波管输能窗口材料,也是目前研究发展的主流趋势。

关键词：太赫兹输能窗金刚石介电性能

Aggregation-induced emission and thermally activated delayed fluorescence of 2,6-diaminobenzophenones

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Science China Chemistry 2018年第8期61卷 925-931页

作者： Masaki Shimizu Masaki Nakatani Kenta nishimura Faculty of Molecular Chemistry and Engineering Kyoto Institute of Technology

Exploration of novel organic luminophores that exhibit thermally activated delayed fluorescence(TADF) in the aggregated state is very crucial for advance of delayed luminescence-based applications such as time-gated bio-sensing and temperature *** report herein that synthesis, photophysical properties, molecular and crystal structures, and theoretical calculations of 2,6-bis(diarylamino)benzophenones. Absorption spectra in solution and calculations using density functional theory(DFT) method revealed that the optical excitation took place through intramolecular charge-transfer from one diarylamino moiety to an aroyl group. While the benzophenones did not luminesce in solution, the solids of the benzophenones emitted green light with moderate-to-good quantum yields. Thus, the benzophenones exhibit aggregation-induced emission. Based on the lifetime measurement, the green emission of the solids was found to include TADF. The emergence of the TADF is supported by the small energy gap between the excited singlet and triplet states, which was estimated by time-dependent DFT calculations. Thin films of poly(methyl methacrylate) doped by the benzophenones also showed green prompt and delayed fluorescence whose lifetimes were in the order of microseconds. Linear correlation between logarithm value of TADF lifetime and temperature was observed with the benzophenone in powder, suggesting that the benzophenones can serve as molecular thermometers workable under aqueous conditions.

关键词： donor-acceptor system delayed fluorescence temperature sensor