检索结果-南通市图书馆

Development and Flow Modes of Vertical Taylor-Couette System with Free Surface

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Mechanics 2014年第3期4卷 90-96页

作者： Takashi Watanabe yorinobu toya Shota Hara Department of Mechanical Engineering Nagano National College of Technology Nagano Japan Graduate School of Information Science Nagoya University Nagoya Japan

We have numerically and experimentally investigated the flow modes of Taylor-Couette system consisting of coaxial two cylinders with vertical axes. The inner cylinder rotates and the outer cylinder and the bottom end of the cylinders remain stationary. The upper top boundary is the free surface of the working liquid between the inner and outer cylinders and it contacts with the air. While this flow appears in fluid machinery and chemical reactors and includes industrial interests, it also contains problems of fluid mechanics, which is about the behavior of the free surface in the rotating field. In this paper, we concretely show the developments of the one cell mode flow and the three cell mode flow at a small aspect ratio. We also represent the bifurcation diagram of the flow at the moderate aspect ratio about 5.5. In the numerical simulation, the flow is rest in the initial state, and the inner cylinder is linearly or suddenly accelerated to attain a flow with a prescribed Reynolds number. When the acceleration of the inner cylinder is high, an imperfect bifurcation occurs and the flows of the secondary modes emerge. At high Reynolds numbers, the flow first has many vortices and then some of the vortices collapse and the final stable flow arises. The loci of the normal five cell mode, the anomalous six cell mode and the secondary seven cell mode are determined.

关键词： Taylor-Couette System Vertical Cylinders Free Surface Flow Mode Mode Transition Bifurcation

Numerical Analysis of Critical Reynolds Number of Wavy Taylor Vortex Flow with Changing Aspect Ratio

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preoperative diagnosis of gastrointestinal stromal tumor by endoscopic ultrasound-guided fine needle aspiration

World Journal of Mechanics（力学国际期刊） 2019年第7期

作者： Hiroyuki Furukawa Takashi Watanabe yorinobu toya

来源：评论

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第14期13卷 2077-2082页

作者： Kazuya Akahoshi yorinobu Sumida Noriaki Matsui Masafumi Oya Rie Akinaga Masaru Kubokawa Yasuaki Motomura Kuniomi Honda Masayuki Watanabe Takashi Nagaie Department of Gastroenterology Aso Iizuka Hospital Iizuka 820-8505Japan Department of Pathology Aso Iizuka Hospital Iizuka 820-8505Japan Department of Surgery Aso Iizuka Hospital Iizuka820-8505Japan

AIM： to evaluate the role of endoscopic ultrasonographyguided fine needle aspiration （EUS-FNA） in the preoperative diagnosis of gastrointestinal stromal tumor （GIST）.METHODS： From September 2002 to June 2006, Fiftythree consecutive EUS-FNAs of GI tract subepithelial hypoechoic tumors with continuity to proper muscle layer suspected as GIST by standard EUS were evaluated prospectively. The reference standards for the final diagnosis were surgery （n = 31）, or clinical follow-up （n = 22）. Additionally, immunophenotyping of specimens obtained by EUS-FNA and surgical resection specimens were compared.RESULTS： In 2 cases puncture was not performed because of anatomical problems. The collection rate of adequate specimens from the GI tract subepithelial hypoechoic tumor with continuity to proper muscle layer was 82% （42/51）. The diagnostic rate for the tumor less than 2 cm, 2 to 4 cm, and 4 cm or more were 71% （15/21）, 86% （18/21）, and 100% （9/9）,respectively. In 29 surgically resected cases, the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of EUS-FNA using immunohistochemical analysis of GIST were 100%（24/24）, 80% （4/5）, 96% （24/25）, 100% （4/4）, and 97% （28/29）, respectively. No major complications were encountered.CONCLUSION： EUS-FNA with immunohistochemical analysis is a safe and accurate method in the pretherapeutic diagnosis of GIST. It should be taken into consideration in decision making, especially in early diagnosis following minimal invasive surgery for GIST.

关键词： Gastrointestinal stromal tumor Ultrasound-guided fine needle aspiration Immunohistochemicalanalysis

Safety advantage of endocut mode over endoscopic sphincterotomy for choledocholithiasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第13期12卷 2086-2088页

作者： Hirotada Akiho yorinobu Sumida Kazuya Akahoshi Atsuhiko Murata Jiro Ouchi Yasuaki Motomura Taisuke Toyomasu Mitsuhide Kimura Masaru Kubokawa Masahiro Matsumoto Shingo Endo Kazuhiko Nakamura Division of Gastroenterology Aso Iizuka Hospital JapanDepartment of Medicine and Bioregulatory ScienceGraduate School of Medical SciencesKyushu UniversityJapan Division of Gastroenterology Aso Iizuka Hospital Japan Division of Surgery Aso Iizuka Hospital Japan Division of Qastroenterology Aso Iizuka Hospital Japan Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu UniversityJapan

AIM： To evaluate whether an automatically controlled cut system （endocut mode） could reduce the complication rate of endoscopic sphincterotomy （EST） and serum hyperamylasemia after EST compared to the conventional blended cut mode. METHODS： From January 2001 to October 2003, 134 patients with choledocholithiasis were assigned to either endocut mode group or conventional blended cut mode group at the time of sphincterotomy. The two groups were retrospectively compared for the complications after EST and serum amylase level before and 24 h after the procedure. RESULTS： Of the 134 patients treated, 79 were assigned to conventional blended cut mode group and 55 to endocut mode group. There was no significant difference in age, sex, and serum amylase level before EST between the two groups. Complications were found in 5 patients of the endocut mode group （9%）： hyperamylasemia （5 times higher than normal） in 4 and moderate pancreatitis in 1. Complications were found in 13 patients of the conventional blended cut mode group （16%）： hyperamylasemia in 12 and moderate pancreatitis in 1. Serum amylase levels were elevated in both groups 24 h after EST （P〈0.02）. The average serum amylase level 24 h after EST in the conventional blended cut mode group was significantly higher than that in the endocut mode group （P〈 0.05）. CONCLUSION： Endocut mode offers a safety advantage over conventional blended cut mode for pancreatitis after EST by reducing hyperamylasemia.

关键词： Endocut mode Endoscopic sphincterotomy Choledocholithiasis

Acute pancreatitis associated with peroral double-balloon enteroscopy: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第11期12卷 1802-1804页

作者： Kuniomi Honda Takahiro Mizutani Kazuhiko Nakamura Naomi Higuchi Kenji Kanayama yorinobu Sumida Shigetaka Yoshinaga Soichi Itaba Hirotada Akiho Ken Kawabe Yoshiyuki Arita Tetsuhide Ito Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu UniversityFukuokaJapan

A 58-year-old Japanese man had tarry stool and severe anemia. Neither upper nor lower gastrointestinal （GI） endoscopy showed any localized lesions. Thus, the source of his GI bleeding was suspected to be in the small intestine, and he underwent peroral double-balloon enteroscopy （DBE） using EN-450T5 （Fujinon-Toshiba ES System Co., Tokyo, Japan）. There were no lesions considered to be the source of GI bleeding. After the procedure, the patient began to experience abdominal pain. Laboratory tests revealed hyperamylasemia and abdominal computed tomography revealed an inflammation of the pancreas and the peripancreas. He was thus diagnosed to have acute pancreatitis. Conservative treatments resulted in both clinical and laboratory amelioration. He had no history of alcohol ingestion, gallstone disease or pancreatitis. Magnetic resonance cholangiopancreatography demonstrated no structural alterations and no stones in the pancreatobiliary ductal system. As his abdominal pain started after the procedure, his acute pancreatitis was thus thought to have been related to the peroral DBE. This is the first reported case of acute pancreatitis probably associated with peroral DBE.

关键词： Enteroscopy Small intestine Pancreatitis complication

Improved techniques for double-balloon-enteroscopy-assisted endoscopic retrograde cholangiopancreatography

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第46期18卷 6843-6849页

作者： Takashi Osoegawa Yasuaki Motomura Kazuya Akahoshi Naomi Higuchi Yoshimasa Tanaka Terumasa Hisano Souichi Itaba Junya Gibo Mariko Yamada Masaru Kubokawa yorinobu Sumida Hirotada Akiho Eikichi Ihara Kazuhiko Nakamura Department of Gastroenterology Aso Iizuka Hospital Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University

AIM: To investigate the clinical outcome of double balloon enteroscopy (DBE)-assisted endoscopic retrograde cholangiopancreatography (DB-ERCP) in patients with altered gastrointestinal anatomy. METHODS: Between September 2006 and April 2011, 47 procedures of DB-ERCP were performed in 28 patients with a Roux-en-Y total gastrectomy (n = 11), Billroth Ⅱ gastrectomy (n = 15), or Roux-en-Y anastomosis with hepaticojejunostomy (n = 2). DB-ERCP was performed using a short-type DBE combined with several technical innovations such as using an endoscope attachment, marking by submucosal tattooing,selectively applying contrast medium, and CO2 insufflations. RESULTS: The papilla of Vater or hepaticojejunostomy site was reached in its entirety with a 96% success rate (45/47 procedures). There were no significant differences in the success rate of reaching the blind end with a DBE among Roux-en-Y total gastrectomy (96%), Billroth Ⅱ reconstruction (94%), or pancreatoduodenectomy (100%), respectively (P = 0.91). The total successful rate of cannulation and contrast enhancement of the target bile duct in patients whom the blind end was reached with a DBE was 40/45 procedures (89%). Again, there were no significant differences in the success rate of cannulation and contrast enhancement of the target bile duct with a DBE among Roux-en-Y total gastrectomy (88 %), Billroth Ⅱ reconstruction (89%), or pancreatoduodenectomy (100%), respectively (P = 0.67). Treatment was achieved in all 40 procedures (100%) in patients whom the contrast enhancement of the bile duct was successful. Common endoscopic treatments were endoscopic biliary drainage (24 procedures) and extraction of stones (14 procedures). Biliary drainage was done by placement of plastic stents. Stones extraction was done by lithotomy with the mechanical lithotripter followed by extraction with a basket or by the balloon pull-through method. Endoscopic sphincterotomy was performed in 14 procedures with a needle precutting knife us

关键词： Double-balloon enteroscopy Endoscopic retrograde cholangiopancreatography Pathological anatomy Pancreatobiliary disease

Efficacy of hybrid endoscopic submucosal dissection with SOUTEN in gastric lesions:An ex vivo porcine model basic study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2021年第6期13卷 563-573页

作者： Mitsuru Esaki Eikichi Ihara Norikazu Hashimoto Shuichi Abe Chihoko Aratono Noriko Shiga yorinobu Sumida Hiroyuki Fujii Kazuhiro Haraguchi Shunsuke Takahashi Tsutomu Iwasa Kayoko Nakano Masafumi Wada Shinichi Somada Kei Nishioka Yosuke Minoda Haruei Ogino Yoshihiro Ogawa Department of Medicine and Bioregulatory Science Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582Japan Department of Gastroenterology and Metabolism Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582Japan Department of Gastroenterology Fukuoka City HospitalFukuoka 811-1394Japan Department of Gastroenterology Harasanshin HospitalFukuoka 812-0033Japan Department of Gastroenterology and Hepatology National Hospital Organization Fukuokahigashi Medical CenterKoga 811-3195Japan Department of Gastroenterology Fukuokaken Saiseikai Futsukaichi HospitalFutsukaichi 811-8516FukuokaJapan Department of Gastroenterology Clinical Research InstituteNational Hospital Organization Kyushu Medical CenterFukuoka 810-8564Japan Department of Gastroenterology Fukuoka Central HospitalFukuoka 805-0050Japan Department of Gastroenterology National Hospital Organization Beppu Medical CenterBeppu 874-0011Japan

BACKGROUND Hybrid endoscopic submucosal dissection(ESD)that comprises mucosal incision and partial submucosal dissection followed by snaring in a planned manner,has been developed for endoscopic resection of gastrointestinal neoplasms to overcome the technical barrier of *** the superiority of hybrid ESD with SOUTEN,a single multifunctional device,over conventional ESD has been indicated,the actual effect of snaring itself remains unclear since SOUTEN could be applied to hybrid ESD group,but not to the conventional ESD group,due to ethical issue in clinical *** To determine whether and how hybrid ESD was superior to conventional ESD in the endoscopic treatment of gastric lesions in an ex vivo porcine model basic *** Sixteen endoscopists participated in this basic study in August 2020 at Kyushu University,performing 32 procedures each for hybrid ESD and conventional *** lesions(10-15 mm,diameter)were created in the porcine *** primary outcome was total procedure time and secondary outcomes were en bloc or complete resection,perforation,procedure time/speed for both,mucosal incision,and submucosal *** associated with difficulty in ESD including longer procedure time,incomplete resection,and perforation,were also *** and continuous data were analyzed using the chi-square test or Fisher’s exact test and the Mann-Whitney U test,*** The median total procedure time of hybrid ESD was significantly shorter than that of conventional ESD(median:8.3 min vs 16.2 min,P<0.001).Time,speed,and the amount of hyaluronic acid during submucosal dissection were more favorable in hybrid ESD than conventional ESD(time,5.2 min vs 10.4 min,P<0.001;speed,43.7 mm^(2)/min vs 23.8 mm^(2)/min,P<0.00;injection volume,1.5 mL vs 3.0 mL,P<0.001),although no significant differences in those factors were observed between both groups during mucosal *** was also no significant difference between both

关键词： Endoscopic mucosal resection Hybrid Stomach neoplasms Treatment outcome Animal experimentation Logistic models

Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virusinfected liver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第11期21卷 3291-3299页

作者： Motoyuki Kohjima Tsuyoshi Yoshimoto Munechika Enjoji Nobuyoshi Fukushima Kunitaka Fukuizumi Tsukasa Nakamura Miho Kurokawa Nao Fujimori Yusuke Sasaki Yasushi Shimonaka Yusuke Murata Susumu Koyama Ken Kawabe Kazuhiro Haraguchi yorinobu Sumida Naohiko Harada Masaki Kato Kazuhiro Kotoh Makoto Nakamuta Department of Gastroenterology and Clinical Research Center National Hospital Organization Kyushu Medical Center Health Care Center Fukuoka University Product Research Department Chugai Pharmaceutical Co.Ltd. Department of Medicine and Bioregulatory Science Kyushu University

AIM:To investigate the relationship between the ironmetabolism-related gene expression profiles and efficacy of antiviral therapy in chronic hepatitis C ***:The hepatic expression profile of ironmetabolism-related genes was analyzed and its association with virological response to pegylated-interferon plus ribavirin combination therapy was evaluated.A hundred patients with chronic hepatitis C(genotype1b,n = 50; genotype 2,n = 50) were enrolled and retrospectively *** biopsy samples were subjected to quantitative polymerase chain reaction for iron-metabolismrelated genes and protein expression(Western blotting analysis) for *** a control,normal liver tissue was obtained from 18 living donors of liver *** hepcidin level was measured by sensitive liquid chromatography/electrospray ionization tandem mass ***:Iron overload is associated with liver damage by increasing oxidative stress and hepatitis C virus(HCV)is reported to induce iron accumulation in hepatocytes in ***,iron administration suppresses HCV replication in ***,the association between HCV infection and iron metabolism remains *** with controls,patients had significantly higher gene expression for transferrin,iron-regulatoryproteins 1 and 2,divalent metal transporter 1,and ferroportin,but similar for transferrin receptors 1 and2,and *** the expression profiles were compared between sustained virological response(SVR)and non-SVR patients,the former showed significantly lower transcription and protein expression of hepcidin and *** of hepcidin-regulating genes,BMPR1,BMPR2,and hemojuvelin,was significantly increased,whereas BMP2 was decreased in HCV-infected ***2 and hemojuvelin expression was significantly lower in the SVR than non-SVR *** infection affects the expression of iron-metabolism-related genes,leading to iron accumulation in ***:Decrea

关键词： Chronic hepatitis C Iron-metabolism Hepcidin Ferro

Mucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2013年第4期5卷 191-196页

作者： Eikichi Ihara Hiroshi Matsuzaka Kuniomi Honda Yoshitaka Hata yorinobu Sumida Hirotada Akiho Tadashi Misawa Satoshi Toyoshima Yoshiharu Chijiiwa Kazuhiko Nakamura Ryoichi Takayanagi Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Department of Gastroenterology Hara-Sanshin General Hospital Department of Gastroenterology Kita-kyushu Municipal Medical Center Department of Pathology Kitakyushu Municipal Medical Center

To evaluate the diagnostic yield of the procedure, mucosal-incision assisted biopsy (MIAB), for the histological diagnosis of gastric gastrointestinal stromal tumor (GIST), we performed a retrospective review of the 27 patients with suspected gastric GIST who underwent MIAB in our hospitals. Tissue samples obtained by MIAB were sufficient to make a histological diagnosis (diagnostic MIAB) in 23 out of the 27 patients, where the lesions had intraluminal growth patterns. Alternatively, the samples were insufficient (non-diagnosticMIAB) in remaining 4 patients, three of whom had gastric submucosal tumor with extraluminal growth patterns. Although endoscopic ultrasound and fine needle aspiration is the gold standard for obtaining tissue specimens for histological and cytological analysis of suspected gastric GISTs, MIAB can be used as an alternative method for obtaining biopsy specimens of lesions with an intraluminal growth pattern.

关键词： Endoscopic ultrasound-guided fine-needle aspiration Gastrointestinal stromal tumor Mucosalincision assisted biopsy Submucosal tumor Endoscopic submucosal dissection