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Cancer Communications 2024年第1期44卷 178-182页

作者： Okan Safak Shenghan Wang Carmen Mota reyes Ibrahim Halil Gürcinar Sergey Tokalov Nedim Can Cevik Kivanc Görgülü Bengi Su Yilmaz Emre Erdogan Linhan Ye Qiaolin Li Elif Arik Sever SamedÖzer Güldal Süyen Helmut Friess Güralp Onur Ceyhan Rouzanna Istvanffy Hana Algül Ihsan Ekin Demir Department of Surgery Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of General Surgery HPB-UnitSchool of MedicineAcibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Comprehensive Cancer Center München Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of Hematology Oncology and Tumor ImmunologyCharitéUniversity Medicine BerlinCampus Virchow ClinicBerlinBerlinGermany Graduate School of Health Sciences Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Department of Physiology Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Else Kröner Clinician Scientist Professorship for Translational Pancreatic Surgery MunichGermany Neural Influences in Cancer(NIC)International Research Consortium MunichGermany

Dear Editor,Targeting the immune compartment in pancreatic duc-tal adenocarcinoma(PDAC)holds promise for prognostic improvement,yet our knowledge on the spatial and tem-poral dynamics and the molecular modulators of t... 详细信息

关键词： immune adenocarcinoma immunotherapy

The Many Faces of Plant SWI/SNF Complex

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Molecular Plant 2014年第3期7卷 454-458页

作者： Jose C. reyes Molecular Biology Department Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER) Consejo Superior de Investigaciones Cientificas (CSIC) Av. Americo Vespucio 41092 Seville Spain

THE SWI/SNF COMPLEXESIn plants, as well as in metazoans, the execution of devel- opmental programs and the response to environmental stimuli depend on changes in gene transcription programs that require extensive chromatin modifications of basically two types： posttranslational modification of histones and ATP-dependent reorganization of histones-DNA interac- tions. Many different nuclear machineries are necessary to carry out chromatin modifications at the appropriate time and place.

关键词： CHROMATIN-REMODELING COMPLEXES ARABIDOPSIS-THALIANA BRAHMA ATPASE RESPONSES GENES ROLES MATURATION REPRESSION SUBUNITS

Radicals and Kothe’s Conjecture for Skew PBW Extensions

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Communications in Mathematics and Statistics 2021年第2期9卷 119-138页

作者： Armando reyes Hector Suarez Departamento de Matematicas Universidad Nacional de ColombiaSede BogotaColombia Escuela de Matemáticas y Estadística Universidad Pedagogica y Tecnológica de ColombiaSede TunjaColombia

The aim of this paper is to investigate different radicals(Wedderburn radical,lower nil radical,Levitzky radical,upper nil radical,the set of all nilpotent elements,the sum of all nil left ideals)of the noncommutative rings known as skew Poincare–Birkhoff–Witt *** characterize minimal prime ideals of these rings and prove that the Kothe’s conjecture holds for these ***,we establish the transfer of several ring-theoretical properties(reduced,symmetric,reversible,2-primal)from the coefficients ring of a skew PBW extension to the extension itself.

关键词： Armendariz rings Kothe’s conjecture Skew PBW extensions

The McCoy Condition on Skew Poincaré-Birkhoff-Witt Extensions

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Communications in Mathematics and Statistics 2021年第1期9卷 1-21页

作者： Armando reyes Camilo Rodriguez Departamento de Matematicas Universidad Nacional de ColombiaSede BogotaColombia

In this paper,we study the notion of McCoy ring over the class of non-commutative rings of polynomial type known as skew Poincare–Birkhoff–Witt *** a consequence,we generalize several results about this notion consi... 详细信息

关键词： McCoy ring Reversible ring Semicommutative ring Zip ring Skew Poincare–Birkhoff–Witt extension

CD74 in antigen presentation,inflammation,and cancers of the gastrointestinal tract

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World Journal of Gastroenterology 2009年第23期15卷 2855-2861页

作者： Ellen J Beswick Victor E reyes Department of Pediatrics University of Texas Medical Branch Galveston TX 77555 United States Department of Pediatrics and Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555 United States

CD74 is a protein whose initial role in antigen presentation was recognized two decades ago. Recent studies have revealed that it has additional functions as a receptor for macrophage migration inhibitory factor and as a receptor for an important human pathogen, Helicobacter pylori （H pylon）. The role of CD74 as a receptor is important because after binding of migration inhibitory factor or H pylori, NF-κB and Erkl/2 activation occurs, along with the induction of proinflammatory cytokine secretion. This review provides an up-to-date account of the functions of CD74 and how it might be involved in inflammation and cancer within the gastrointestinal tract.

关键词： CD74 Invariant chain Cancer Inflammation Helicobacterpylori Gastrointestinal tract

Effect of successive sprays on liquid distribution in fluidized beds

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Particuology 2021年第1期19卷 17-24页

作者： Cedric Briens Liliana Pardo reyes Franco Berruti Jennifer McMillan Institute for Chemicals and Fuels from Alternative Resources Western University22312 Wonderland Rd.IldertonONN0M 2A0Canada Edmonton Research Centre Syncrude Canada Ltd942117th AveEdmontonABT6N 1H4 Canada

In processes such as Fluid Coking^(™),agglomerate formation should be minimized since it reduces the yield of valuable products,and degrades operability because of the fouling of *** experimental model,consisting of an aqueous solution of gum arabic with a dye,has been successfully developed to simulate the formation of agglomerates in the Fluid Coking^(™)process,where bitumen is sprayed into a fluidized bed of coke particles The particles wetted by a spray could be predicted by assuming that all the particles in the wake of bubbles formed from the tip of the spray jet have been wetted by the injected *** transfer of liquid from particles wetted with the spray to dry bed particles was relatively ineffective,as the number of wet particles increased by only 50%.With successive liquid injections,the proportion of the liquid trapped in agglomerates increases in latter injections:large agglomerates from earlier injections accumulate above the grid and are carried by gas bubbles into the spray jet cavity,where they seed fresh agglomerates.

关键词： Fluidized bed Liquid injection Agglomerate formation Fluid Coker

Using music to reduce anxiety among older adults in the emergency department:a randomized pilot study

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Journal of Integrative Medicine 2017年第6期15卷 450-455页

作者： Laura Belland Laura Rivera-reyes Ula Hwang center for family medicine newyork-presbyterian/columbia university medical centerNew YorkNY 10032USA department of emergency medicine icahn school of medicine at mount sinaiNew YorkNY 10029USA geriatric research education and clinical centerjames j.peters vamcNew YorkNY 10029USA

BACKGROUND： An emergency department （ED） visit may be distressing and anxiety-provoking for older adults （age 〉 65 years）. No studies have specifically evaluated the effect of music listening on anxiety in older adults in the ED. OBJECTIVE： The objective of this pilot study was to evaluate the effect of music listening on anxiety levels in older ED patients. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This was a randomized pilot study in the geriatric ED of an urban academic tertiary medical center. This was a sample of English-speaking adults （age 〉 65 years） who were not deaf （n = 35）. Subjects consented to participate and were randomized to receive up to 60 min of music listening with routine care, while the control group received routine care with no music. Subjects in the music treatment group received headphones and an electronic tablet with pre-downloaded music, and were allowed to choose from 5 selections. MAIN OUTCOME MEASURES： The primary outcome was change in anxiety levels, measured by the state- trait anxiety inventory （STAI）, at enrollment and 1 h later. RESULTS： A total of 35 participants were enrolled： 74% were female, 40% were white, and 40% were black; of these, 32 subjects completed the study protocol. When comparing control （n = 18） against intervention subjects （n = 17）, there were no significant differences in enrollment STAI scores （43.00 ± 15.00 vs. 40.30± 12.80, P = 0.57）. STAI scores 1 hour after enrollment （after the music intervention） were significantly reduced in the intervention subjects compared to the control subjects （with reduction of 10.00± 12.29 vs. 1.88 ± 7.97, P = 0.03）. CONCLUSION： These pilot results suggest that music listening may be an effective tool for reducing anxiety among older adults in the ED.

关键词： music anxiety emergency department randomized controlled trial

Neural functions of small heat shock proteins

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Neural Regeneration Research 2022年第3期17卷 512-515页

作者： Teresa de los reyes Sergio Casas-Tintó Instituto Cajal CSICMadridSpain

Stress response is a cellular widespread mechanism encoded by a common protein program composed by multiple cellular factors that converge in a defense reaction to protect the cell against *** many mechanisms described,heat shock proteins were proposed as universally conserved protective factors in the stress core proteome,coping with different stress stimuli through its canonical role in protein ***,emerging evidences reveal non-canonical roles of heat shock proteins relevant for physiological and pathological ***,we review the implications of inducible heat shock proteins in the central nervous system *** particular,we discuss the relevance of heat shock proteins in the maintenance of synapses,as a balanced protective mechanism in central nervous system development,pathological conditions and aging.

关键词： aging central nervous system chaperones environment neuroprotection pathology stress synapses

The Beauty of Being a Variant： H2A.Z and the SWR1 Complex in Plants

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Molecular Plant 2009年第4期2卷 565-577页

作者： Rosana March-Diaz Jose C. reyes Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) CSIC Americo Vespucio s/n E-41092 Sevilla Spain

Numerous studies have shown that the nucleosome is a dynamic structure that strongly influences gene expression. Dynamism concerns different nucleosomal characteristics, including position, posttranslational modifications, and histone composition. Thus, within the nucleosome, canonical histones can be exchanged by histone variant proteins with specific functions--a process known as ‘histone replacement＇. The histone variant H2A.Z has an important function in transcription and, during the last few years, its role in plant development and immune response has become evident. Compiling genetic and biochemical studies from several laboratories has revealed that plants contain a multiprotein complex, similar to the SWR1/SRCAP complex from yeast and animals, involved in H2A.Z deposition. Despite intense research in different organisms, the mechanism by which H2A.Z influences transcription is still unknown. However, recent results from Arabidopsis have shown a strong inverse correlation between H2A.Z and DNA methylation, suggesting that H2A.Z might protect genes from silencing.

关键词： Chromatin structure and remodeling epigenetics gene regulation floral induction.

Mind the gap among patches in arid plant communities:rapid root proliferation in response to N addition

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Journal of Plant Ecology 2019年第1期12卷 89-95页

作者： Maria Fernanda reyes Martín RAguiar Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura(IFEVA)and Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Universidad de Buenos AiresAv.San Martín 4453Buenos Aires C1417DSEArgentina

Aims In arid communities,it has been proposed that individual plants can extend their roots beyond their canopy exploring neighbour-ing bare ground *** becomes relevant in systems where the vegetation is distributed in patches surrounded by bare ***,whether roots of different species may be overlapping under bare ground areas is still *** factors control-ling root responses when no plants appear to be directly influ-encing the gap among patches are still *** aim of our study was to detect perennial grasses responses to an N enrich-ment *** In a semi-arid steppe(Patagonia,Argentina),we buried root traps filled with sieved soil with and without N addition,under bare soil *** were harvested after 4 and 6 *** neighbour-hoods(30 cm in diameter)included at least three of the dominant tussock *** harvests,we identified species in the traps by root traits and quantified diversity,biomass and specific relative growth *** Findings Bare ground areas show simultaneous root growth of different *** of perennial grass roots was higher with N addition than without it in the first harvest(4 months),but this difference disappeared in the second harvest(6 months).Root biomass was maximal after 6 months in N addition *** preferred by herbivores(Bromus pictus and Poa ligularis)showed rapid growth and responses to N *** between harvests may be an indicative that N pulses interact with rising temperatures and soil water content as growing season progress.

关键词： belowground community ecology grass species roots Patagonian steppe patchiness root growth rates zone of influence