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An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs

Bio-Design and Manufacturing 2024年第3期7卷 240-261页

作者： Seol-Ha jeong Jarno Hiemstra Patrick V.Blokzijl Rebeca Damian-Ferrara Danilo Martins dos Santos Jéssica H.L.da Fonseca Min-Ho Kang Jihyun Kim Dilara Yilmaz-Aykut Mei L.L.Cham-Pérez Jeroen Leijten su Ryon Shin Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA Leijten Lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department of Biomedical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

关键词： 3D bioprinting Bioink Colloidal gels Extrusion printing Oxygen-generating microparticle

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High Na-ion conductivity andmechanical integrity of anion-exchanged polymeric hydrogel electrolytes for flexible sodium ion hybrid energy storage

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susMat 2024年第1期4卷 140-153页

作者： JungWoo Hong Harpalsinh H.Rana jeong Hee Park Jun su Kim Sang Joon Lee Gun Jang Tae Hoon Kang Kang Ho Shin Sang Ha Baek Wooseok Yang Kwang Ho Kim Ju-Hyuk Lee Ho Seok Park School of Chemical Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Clean Energy Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST-SKKU Carbon-Neutral Research Center Sungkyunkwan University(SKKU)SuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea COSMOS LAB/92 Jomaru-ro 385beon-gilBucheon-siRepublic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea

The polymeric gel electrolytes are attractive owing to their higher ionic conductivities than those of dry polymer electrolytes and lowered water activity for enlarged potential ***,the ionic conductivity and mechanical strength of the Na-ion conducting polymeric gel electrolytes are limited by below 20 mS cm−1 and 2.2 ***,we demonstrate Na-ion conducting and flexible polymeric hydrogel electrolytes of the chemically coupled poly(diallyldimethylammonium chloride)-dextrin-N,N′-methylene-bisacrylamide film immersed in NaClO_(4) solution(ex-DDA-Dex+NaClO_(4))for flexible sodium-ion hybrid capacitors(f-NIHC).In particular,the anion exchange reaction and synergistic interaction of ex-DDA-Dex with the optimum ClO_(4)−enable to greatly improve the ionic conductivity up to 27.63 mS cm−1 at 25◦C and electrochemical stability window up to 2.6 V,whereas the double networking structure leads to achieve both the mechanical strength(7.48 MPa)and softness of hydrogel ***,the f-NIHCs with the ex-DDA-Dex+NaClO_(4) achieved high specific and high-rate capacities of 192.04 F g^(−1)at 500 mA g^(−1)and 116.06 F g^(−1)at 10000 mA g^(−1),respectively,delivering a large energy density of 120.03Wh kg^(−1)at 906Wkg^(−1)and long cyclability of 70%over 500 cycles as well as demonstrating functional operation under mechanical stresses.

关键词： anion exchange chemistry flexible energy storage hybrid energy storage hydrogel electrolytes renewable electrolytes sodium storage

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Catalpa bignonioides extract improves exercise performance through regulation of growth and metabolism in skeletal muscles

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 47-54页

作者： Hoibin jeong Dong-joo Lee sung-Pil Kwon SeonJu Park Song-Rae Kim Seung Hyun Kim Jae-Il Park Deug-chan Lee Kyung-Min Choi WonWoo Lee Ji-Won Park Bohyun Yun su-Hyeon Cho Kil-Nam Kim Seoul Center Korea Basic Science InstituteSeoul 02841Republic of Korea Chuncheon Center Korea Basic Science InstituteChuncheon 24341Republic of Korea Research&Development Center Chungdam CDC JNPharm LLC.Chuncheon 24341Republic of Korea Department of Biomedical Technology Kangwon National UniversityChuncheon 24341Republic of Korea Yonsei Institute of Pharmaceutical Sciences College of PharmacyYonsei UniversityIncheon 21983Republic of Korea Gwangju Center Korea Basic Science InstituteGwangju 61751Republic of Korea Honam National Institute of Biological Resources 99Gohadoan-gilMokpo-siJeollanam-do58762Republic of Korea Department of Bio-analysis Science University of Science&TechnologyDaejeon34113Republic of Korea

Objective:To evaluate the effects of Catalpa bignonioides fruit extract on the promotion of muscle growth and muscular capacity in vitro and in ***:Cell viability was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** proliferation was assessed using a 5-bromo-2’-deoxyuridine(BrdU)assay *** blot analysis was performed to determine the protein expressions of related *** effects of Catalpa bignonioides extract were investigated in mice using the treadmill exhaustion test and whole-limb grip strength *** composition analysis was performed using high-performance liquid chromatography(HPLC).Results:Catalpa bignonioides extract increased the proliferation of C2C12 mouse myoblasts by activating the Akt/mTOR signaling *** also induced metabolic changes,increasing the number of mitochondria and glucose metabolism by phosphorylating adenosine monophosphate-activated protein *** an in vivo study,the extract-treated mice showed improved motor abilities,such as muscular endurance and grip ***,HPLC analysis showed that vanillic acid may be the main component of the Catalpa bignonioides extract that enhanced muscle ***:Catalpa bignonioides improves exercise performance through regulation of growth and metabolism in skeletal muscles,suggesting its potential as an effective natural agent for improving muscular strength.

关键词： Catalpa bignonioides Skeletal muscle Cell proliferation Mitochondria Energy metabolism C2C12

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Energy efficient mechanism using flexible medium access control protocol for hybrid wireless sensor networks

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Journal of Central South University 2013年第8期20卷 2165-2174页

作者： suN Ning jeong yoon-su LEE Sang-ho Department of Computer Science Chungbuk National University Department of Information Communication Engineering Mokwon University

Energy efficiency is a primary consideration in a wireless sensor network (WSN). This is also a major parameter when designing a medium access control (MAC) protocol for WSNs. Hierarchical clustering structure is regarded suitable for WSNs due to its good performance in energy conservation. In this work, an adequately flexible mechanism for clustering WSNs is designed, in which some creative or promotional metrics are utilized, such as cluster head selection algorithm, cluster optional reconstruction, interested data transmission, multiple path routing protocol. All these strategies were cooperated to maximize energy saving of whole system. An appropriate MAC protocol for this mechanism is proposed, by flexibly switching the status of diverse sensor nodes in different strategies. The simulation results show that the proposed MAC protocol is suitable for clustering WSNs and performs well in aspects of energy efficiency, flexibility and scalability.

关键词： MAC protocol energy conservation flexibility re-clustering wireless sensor network

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Efficient and secure source authentication scheme for multicast user authentication

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Journal of Central South University 2013年第10期20卷 2741-2746页

作者： jeong yoon-su LEE Sang-hyuk SHIN Seung-soo Department of Information Communication Engineering Mokwon University Department of Electrical and Electronic Engineering Xi’an Jiaotong-Liverpool University Department of Information Security Tongmyong University

Multicast technology application has been widely utilized in broadband internet. Source authentication is one of the most needs for many multicast applications transferring real-time information such as stream video and online news. Because multicast current services provided to the group members are changed dynamically, data transferring by a group member is not used by the recipient. In order to verify the identity of the sender who sent the packet and to make sure that the data have not been tampered, an optimized source authentication scheme has been proposed to transfer the authentication information not to the next-door packet. The proposed method for multiple packets authenticates the source with a limited number of electronic signatures. The proposed method can reduce overhead compared to the method by adding a digital signature for every packet. In addition, by sending the generated electronic signature to the first packet and the last packet, it prevents the loss of consecutive packets, as well as a source authentication can be provided in real-time services.

关键词： multicast packet source authentication broadband Internet

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Journal of Central South University 2014年第9期21卷 3534-3540页

作者： LEE Sang-hyuk YAN sun jeong yoon-su SHIN Seung-soo Department of Electrical and Electronic Engineering Xi'an Jiaotong-Liverpool University International Business School suzhou Xi'an Jiaotong-Liverpool University Department of Information Communication Engineering Mokwon University Department of Information Security Tongmyong University

Information analysis of high dimensional data was carried out through similarity measure application. High dimensional data were considered as the a typical structure. Additionally, overlapped and non-overlapped data were introduced, and similarity measure analysis was also illustrated and compared with conventional similarity measure. As a result, overlapped data comparison was possible to present similarity with conventional similarity measure. Non-overlapped data similarity analysis provided the clue to solve the similarity of high dimensional data. Considering high dimensional data analysis was designed with consideration of neighborhoods information. Conservative and strict solutions were proposed. Proposed similarity measure was applied to express financial fraud among multi dimensional datasets. In illustrative example, financial fraud similarity with respect to age, gender, qualification and job was presented. And with the proposed similarity measure, high dimensional personal data were calculated to evaluate how similar to the financial fraud. Calculation results show that the actual fraud has rather high similarity measure compared to the average, from minimal 0.0609 to maximal 0.1667.

关键词： high dimensional data similarity measure difference neighborhood information financial fraud

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A Unified Buffering Management with Set Divisible Cache for PCM Main Memory

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Journal of Computer Science & Technology 2016年第1期31卷 137-146页

作者： Mei-Ying Bian su-Kyung yoon jeong-Geun Kim Sangjae Nam Shin-Dug Kim Department of Computer Science Yonsei University Seoul 120-749 Korea

This research proposes a phase-change memory （PCM） based main memory system with an effective combi- nation of a superblock-based adaptive buffering structure and its associated set divisible last-level cache （LLC）. To achieve high performance similar to that of dynamic random-access memory （DRAM） based main memory, the superblock-based adaptive buffer （SABU） is comprised of dual DRAM buffers, i.e., an aggressive superblock-based pre-fetching buffer （SBPB） and an adaptive sub-block reusing buffer （SBRB）, and a set divisible LLC based on a cache space optimization scheme. According to our experiment, the longer PCM access latency can typically be hidden using our proposed SABU, which can significantly reduce the number of writes over the PCM main memory by 26.44%. The SABU approach can reduce PCM access latency up to 0.43 times, compared with conventional DRAM main memory. Meanwhile, the average memory energy consumption can be reduced by 19.7%.

关键词： memory hierarchy memory structure,cache memory buffer management

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Growth and Magnetic Properties of Sol-Gel Derived Co-Doped ZnO Thin Film

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Journal of Rare Earths 2006年第z1期24卷 59-63页

作者： Young sung Kim Ki Chul Kim Won Pil Tae Dae Ho yoon Tae Seok Park su jeong suh Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Cambridge-ETRI Joint R&D Centre Electronics and Telecommunications Research Institute Daejeon 305-350 Korea Ulsan Industry Promotion Techno Park Ulsan 683-804 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea

Zn1-xCoxO films were grown on glass by sol-gel spin coating process. A homogeneous and stable Zn1-xCoxO sol was prepared by dissolving zinc acetate dihydrate, cobalt acetate tetrahydrate and aluminium chloride hexahydrate as solutes in solution of isopropanol and monoethanolamine. The films were postheated and vacuum annealed, and investigated for c-axis preferred orientation and electromagnetic properties. Zn1-xCoxO films with different Co concentrations were oriented well along the c-axis, especially the Zn1-xCoxO film with 10% Co(atom fraction) was highly c-axis oriented. The transmittance spectra show that Zn1-xCoxO films occur d-d transition and sp-d exchange interaction between Co2+ ions. The electrical resistivity of the films at 10% Co had the lowest value because the crystallite size became largest and the crystallinity of the c-axis was improved. X-ray photoelectron spectroscopy and alternating gradient magnetometer analyses indicated that no Co metal cluster was formed, and the ferromagnetism at room temperature appeared. The characteristics of the electrical resistivity and room temperature ferromagnetism of sol-gel derived Zn1-xCoxO films suggest a potential application of dilute magnetic semiconductor devices.

关键词： sol-gel Zn1-xCoxO thin film dilute magnetic semiconductor (DMS)

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Challenges and opportunities for using formate to store, transport, and use hydrogen

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Journal of Energy Chemistry 2020年第2期29卷 216-224页

作者： Katarzyna Grubel Hyangsoo jeong Chang Won yoon Tom Autrey Pacific Northwest National Laboratory 902 Battelle Boulevard.P.O.Box 999.Richland.WA 99352.United States Center for Hydrogen and Fuel Cell Research Korea Institute of Science and Technology(KIST).5 Hwarang-ro 14-gil.Seongbuk-gu.Seoul 02792Republic of Korea Divison of Energy and Environment Technology KIST SchoolKorea University of Science and Technology5 Hwarung-ro 14-gil.Seongbuk-guSeoul 02792.Republic of Korea KHU-KIST Department of Converging Science and Technology Kyung Hee University26 Kyungheedae-ro.Dongdaemun-guSeoul 02447Republic of Korea

In this perspective article,the synthesis and thermodynamic properties of aqueous solutions of formate salts(FS,HCO2-)are described in relationship to the concept of *** physiochemical properties of solid FS,aqueous formate solutions,and aqueous bicarbonate solutions set the limitations for storage capacity,deliverable capacity,and usable H2capacity of these H2carriers,*** parameters will help in the design of systems that use H2carriers for storage and transport of H2for fuel cell power ***,as well as admixtures with formic acid(FA,H2CO2),have potential to address the goals outlined in the *** of Energy’s H2@scale initiative to store in chemical bonds a significant quantity of energy(hundreds of megawatts)obtained from large scale renewable resources.

关键词： Hydrogen carriers Formate salts Bicarbonate salts Thermodynamics

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Nuclear symmetry energy from QCD sum rules

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Nuclear Science and Techniques 2013年第5期24卷 31-33页

作者： jeong Kie Sang LEE su Houng Institute of Physics and Applied Physics Yonsei University

We calculated the nucleon self-energies in iso-spin asymmetric nuclear matter and obtained the nuclear symmetry energy by taking difference of these of neutron and *** find that the scalar(vector) self-energy part gives a negative(positive) contribution to the nuclear symmetry energy,consistent with the result from relativistic mean-field ***,we found exact four-quark operator product expansion for nucleon sum *** them,twist-4 matrix elements which can be extracted from deep inelastic scattering experiment constitute an essential part in the origin of the nuclear symmetry energy from *** result also extends early success of QCD sum rule in the symmetric nuclear matter to the asymmetric nuclear matter.

关键词： QCD求和规则对称能非对称核物质相对论平均场理论核电矩阵元素散射实验对称性

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