检索结果-南通市图书馆

Effects of Initial and Boundary Conditions on Heavy Rainfall Simulation over the Yellow Sea and the Korean Peninsula:Comparison of ECMWF and NCEP Analysis Data Effects and Verification with Dropsonde Observation

引用

Advances in Atmospheric Sciences 2024年第9期41卷 1787-1803页

作者： Jiwon HWANG Dong-Hyun cha Donghyuck yoon Tae-Young GOO Sueng-Pil JUNG Department of Civil Urban Earth and Environmental Engineering Ulsan National Institute of Science and TechnologyUlsan 44919South Korea Program in Atmospheric and Oceanic Sciences Princeton UniversityPrincetonNew Jersey 08544USA National Institute of Meteorological Sciences NIMSJeju 63568South Korea

This study evaluated the simulation performance of mesoscale convective system(MCS)-induced precipitation,focusing on three selected cases that originated from the Yellow Sea and propagated toward the Korean *** evaluation was conducted for the European Centre for Medium-Range Weather Forecasts(ECMWF)and National Centers for Environmental Prediction(NCEP)analysis data,as well as the simulation result using them as initial and lateral boundary conditions for the Weather Research and Forecasting ***,temperature and humidity profiles from 3D dropsonde observations from the National Center for Meteorological Science of the Korea Meteorological Administration served as validation *** showed that the ECMWF analysis consistently had smaller errors compared to the NCEP analysis,which exhibited a cold and dry bias in the lower levels below 850 *** model,in terms of the precipitation simulations,particularly for high-intensity precipitation over the Yellow Sea,demonstrated higher accuracy when applying ECMWF analysis data as the initial *** advantage also positively influenced the simulation of rainfall events on the Korean Peninsula by reasonably inducing convective-favorable thermodynamic features(i.e.,warm and humid lower-level atmosphere)over the Yellow *** conclusion,this study provides specific information about two global analysis datasets and their impacts on MCS-induced heavy rainfall simulation by employing dropsonde observation ***,it suggests the need to enhance the initial field for MCS-induced heavy rainfall simulation and the applicability of assimilating dropsonde data for this purpose in the future.

关键词： initial conditions dropsonde heavy rainfall forecast global model analysis evaluation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

运动不耐受诊断标准:Bárány协会分类委员会共识文件

引用

神经损伤与功能重建 2022年第12期17卷 687-695页

作者：宋宁(译) 邢玥(译) 李康之(译) 金占国(审校) 杨旭(审校) yoon-hee cha John F.Golding Behrang Keshavarz Joseph Furman Ji-Soo Kim Jose A.Lopez-Escamez Måns Magnusson Bill J.Yates Ben D.Lawson Jeffrey P.Staab(顾问) Alexandre Bisdorff(顾问) 航天中心医院(北京大学航天临床医学院)神经内科北京大学首钢医院神经内科中国人民解放军空军特色医学中心眩晕中心明尼苏达大学神经病学系美国明尼苏达州明尼阿波里斯市威斯敏斯特大学社会科学学院心理学英国伦敦多伦多康复研究所-多伦多综合医院加拿大安大略省多伦多市瑞尔森大学心理学系加拿大安大略省多伦多市匹兹堡大学耳鼻咽喉科美国宾夕法尼亚州匹兹堡首尔大学神经病学系韩国首尔格拉纳达大学耳鼻咽喉科外科西班牙格拉纳达辉瑞公司/格拉纳达大学/安达卢西亚(GENyO)基因组与肿瘤研究中心基因组医学系耳科和神经科小组CTS495 PTS西班牙格拉纳达涅维斯圣女医院生物卫生研究所耳鼻喉科西班牙格拉纳达隆德大学耳鼻喉科瑞典隆德匹兹堡大学耳鼻喉科美国宾夕法尼亚州匹兹堡新伦敦海军潜艇基地海军潜艇医学研究实验室美国康涅狄格州格罗顿梅奥诊所精神心理学系美国明尼苏达州罗彻斯特 EmileMayrisch医疗中心神经内科卢森堡阿尔泽特河畔埃施

我们提出了运动不耐受(motion sickness,MS),视觉诱发运动不耐受(visually induced motion sickness,VIMS),运动病(motion sickness disorder,MSD)和视觉诱发运动病(visually induced motion sickness disorder,VIMSD)的诊断标准,这些标准将被纳入国际前庭疾病分类。MS和VIMS是一种正常生理反应,几乎所有人都可能出现,但在某些情况下,个体对这种反应的易感性和严重性过高则被认为是一种疾病。本文提供了对由躯体运动或视觉运动引起的症状和体征的评价标准及个体反应严重程度是否可构成疾病诊断的指南。MS和VIMS的诊断标准包括由于暴露于躯体运动或视觉运动所引发的不良反应,通常导致在以下方面出现严重程度大于最低限度的症状或体征:恶心和/或胃肠道功能紊乱、体温调节功能紊乱、觉醒水平改变、头晕和/或眩晕、头痛和/或眼疲劳。这些症状/体征在暴露于运动状态时出现,随着暴露时间延长而加重,最终随运动结束而消失。当相同或相似的刺激反复诱发MS或VIMS发作,其严重程度在反复暴露后没有明显减轻,且因症状/体征而调整活动状态、避免参与诱发不耐受的运动刺激或负性情绪反应时,即可诊断为MSD和VIMSD。MS/MSD和VIMS/VIMSD可以单独出现,也可同时出现。由躯体运动或视觉运动刺激诱发的症状严重程度个体差异较大,并且同一个体也会因年龄、适应能力及合并疾病的变化而发生改变。本文探讨了评估MS症状的主要方法,易出现MS和VIMS相关情境以及导致易感性增加相关的个体特征。对上述环境和个人因素特征的准确评估及理解,将有助于MSD和VIMSD的诊断优化。

关键词：躯体运动诊断标准胃肠道功能紊乱活动状态运动病眼疲劳疾病诊断 MS/MS

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

ELK3-ID4 axis governs the metastatic features of triple negative breast cancer

引用

Oncology Research 2024年第1期32卷 127-138页

作者： JIN-HO CHOI JOO DONG PARK SEUNG hee CHOI EUN-SU KO HYE JUNG JANG KYUNG-SOON PARK Department of Biomedical Science CHA UniversitySeongnamKorea

Purpose:Cancer cell metastasis is a multistep process,and the mechanism underlying extravasation remains ***3 is a transcription factor that plays a crucial role in regulating various cellular processes,including cancer *** on the finding that ELK3 promotes the metastasis of triple-negative breast cancer(TNBC),we investigated whether ELK3 regulates the extravasation of TNBC by forming the ELK3-ID4 ***4 functions as a transcriptional regulator that interacts with other transcription factors,inhibiting their activity and subsequently influencing various biological processes associated with cell differentiation,survival,growth,and ***:We assessed the correlation between the expression of ELK3 and that of ID4 in TNBCs using bioinformatics analyses,QRT-PCR,western blot analysis,luciferase reporter assays,and chromatin ***,adhesion,invasion,and lung metastasis assays were employed to determine whether the ELK3-ID4 axis regulates the metastatic features of ***:We found that ELK3 binds directly to a binding motif close to the ID4 promoter to repress promoter *** expression of E-cadherin in TNBC was regulated by the ELK3-ID4 *** vitro and in vivo analyses showed that inhibiting ID4 expression in ELK3-knockdown MDA-MB-231(ELK3KD)cells restored the ability to extravasate and ***:The results indicate that the ELK3 regulates ID4 promoter activity,and that the ELK3-ID4 axis regulates the metastatic characteristics of TNBC ***,the data suggest that the ELK3-ID4 axis regulates metastasis of TNBCs by modulating expression of E-cadherin.

关键词： E-cadherin Extravasation Colonization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

登陆病综合征诊断标准:Bárány协会前庭疾病分类委员会共识

引用

神经损伤与功能重建 2021年第12期16卷 683-687页

作者：宋宁(译) 李响(译) 张梦露(译) 隋汝波(审校) 杨旭(审校) yoon-hee cha Robert W.Baloh Catherine Cho Måns Magnusson Jae-Jin Song Michael Strupp Floris Wuyts Jeffrey P.Staab 航天中心医院(北京大学航天临床医学院)神经内科锦州医科大学附属第一医院神经内科美国明尼苏达大学神经病学系美国加州大学洛杉矶分校神经病学系美国纽约大学格罗斯曼医学院神经内科和耳鼻喉-头颈外科瑞典隆德大学耳鼻喉科韩国首尔大学盆唐医院耳鼻喉-头颈外科德国慕尼黑大学神经内科德国眩晕与平衡疾病中心比利时安特卫普平衡研究与航空航天实验室(LEIA) 美国明尼苏达州罗彻斯特市梅奥诊所精神心理学系和耳鼻喉-头颈外科

我们提出了登陆病综合征(mal de débarquement syndrome,MdDS)的诊断标准,并将其纳入国际前庭疾病分类。这些诊断标准包括:(1)非旋转性眩晕,其特征是持续性或1天中大部分时间都存在振荡感("摇摆"、"摆动"或"晃动");(2)被动运动结束后4... 详细信息

我们提出了登陆病综合征(mal de débarquement syndrome,MdDS)的诊断标准,并将其纳入国际前庭疾病分类。这些诊断标准包括:(1)非旋转性眩晕,其特征是持续性或1天中大部分时间都存在振荡感("摇摆"、"摆动"或"晃动");(2)被动运动结束后48小时内发作;(3)症状在被动运动时(例如驾驶)可暂时减轻;(4)症状持续>48小时。病程不足1月且症状仍持续者,定义为"进展型";如果症状在1个月或1个月内得以缓解,观察期至少延长到缓解点,则为"短暂型";如果症状持续超过1个月不缓解,则为"持续型"。事实上,MdDS患者亦可伴发空间定向障碍、视觉运动不耐受、疲劳以及头痛或焦虑加剧的症状。本文也回顾总结了MdDS与前庭性偏头痛、运动病及持续性姿势-感知性头晕(persistent postural perceptual dizziness,PPPD)的临床鉴别要点。此外,非运动触发、可通过运动缓解的振荡性眩晕在其他前庭疾病、内科疾病、精神紧张加剧或代谢紊乱之后出现,由于其具有MdDS和PPPD这2种疾病的特点,在非运动诱发的表现描述方面多样,因此,进一步研究其现象及生物学与MdDS、PPPD及其他前庭疾病的相关性是非常有必要的。

关键词：登陆病综合征 MdDS 被动运动非运动触发的持续性振荡性眩晕持续性姿势-感知性头晕

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparative analyses of the venom components in the salivary gland transcriptomes and saliva proteomes of some heteropteran insects

引用

Insect Science 2022年第2期29卷 411-429页

作者： Kyungjae Andrew yoon Woo-Jin Kim Seungki Lee hee-Sun Yang Byoung-hee Lee Si Hyeock Lee Research Institute of Agriculture and Life Sciences Seoul National UniversitySeoulKorea EntoCode Co. SeoulKorea National Institute of Biological Resources Environmental Research ComplexIncheonKorea Department of Agricultural Biology Seoul National UniversitySeoulKorea

Salivary gland-specific transcriptomes of nine heteropteran insects with distinct feeding strategies (predaceous, hematophagous, and phytophagous) were analyzed and annotated to compare and identify the venom components as well as their expression profiles. The transcriptional abundance of venom genes was verified via quantitative real-time PCR. Hierarchical clustering of 30 representative differentially expressed venom genes from the nine heteropteran species revealed unique groups of salivary gland-specific genes depending on their feeding strategy. The commonly transcribed genes included a paralytic neurotoxin (arginine kinase), digestive enzymes (cathepsin and serine protease), an anti-inflammatory protein (cystatin), hexamerin, and an odorant binding protein. Both predaceous and hematophagous (bed bug) heteropteran species showed relatively higher transcription levels of genes encoding proteins involved in proteolysis and cytolysis, whereas phytophagous heteropterans exhibited little or no expression of these genes, but had a high expression of vitellogenin, a multifunctional allergen. Saliva proteomes from four representative species were also analyzed. All venom proteins identified via saliva proteome analysis were annotated using salivary gland transcriptome data. The proteomic expression profiles of venom proteins were in good agreement with the salivary gland-specific transcriptomic profiles. Our results indicate that profiling of the salivary gland transcriptome provides important information on the composition and evolutionary features of venoms depending on their feeding strategy.

关键词： hematophagous heteroptera phytophagous predaceous proteome analysis salivary gland-specific venom transcriptome analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A new analytical approach for identifying market contagion

引用

Financial Innovation 2022年第1期8卷 1097-1131页

作者： hee Soo Lee Tae yoon Kim Department of Business Administration Sejong University209 Neungdong-ro Gwangjin-guSeoul 05006Korea Department of Statistics Keimyung University1095 Dalgubeol-daeroDaegu 704-701Korea.

This study proposed a new analytical approach to identify the excessive comovement of two markets as *** goal is achieved by linking latent-factor and single-equation error correction models and evaluating the breaks in the short-and long-term relationships and correlatedness in the linked *** results demonstrated that a short-term relationship representing the market speed ratio between two markets plays a key role in contagion *** a long-term relationship or correlatedness is broken(comovement change)due to a break in the short-term relationship(market speed ratio),contagion is highly likely and should be formally *** posterior probabilities were calculated to determine the ***,this study applied this analytical Bayesian approach to empirically test the contagion effects of the *** market during the global financial crisis between 2007 and 2009 using 22 developed equity markets.

关键词： Contagion test Market integration Bayesian approach Comovement Market speed ratio

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ultrasound-guided intra-articular corticosteroid injection in a patient with manubriosternal joint involvement of ankylosing spondylitis:A case report

引用

World Journal of Clinical Cases 2023年第9期11卷 2043-2050页

作者： Min-hee Choi In-Young yoon Won-Joong Kim Department of Anesthesiology and Pain Medicine Ewha Womans University Mokdong HospitalSeoul 07985South Korea

BACKGROUND Manubriosternal joint(MSJ)disease is a rare cause of anterior chest pain but can be a major sign of systemic arthritic *** patients with ankylosing spondylitis(AS),a type of systemic arthritis,chest pain can be due to MSJ involvement and can be improved by ultrasound-guided corticosteroid injection into the *** SUMMARY A 64-year-old man visited our pain clinic complaining of anterior chest *** were no abnormal findings on lateral sternum X-ray,but arthritic changes in the MSJ were observed on single-photon emission computed tomography-computed *** performed additional laboratory tests,and he was finally diagnosed with *** pain relief,we performed ultrasound-guided intra-articular(IA)corticosteroid injections into the *** the injections,his pain nearly *** For patients complaining of anterior chest pain,AS should be considered,and single-photon emission computed tomography-computed tomography can be helpful in *** addition,ultrasound-guided IA corticosteroid injections may be effective for pain relief.

关键词： Ankylosing spondylitis Anterior chest pain Manubriosternal joint Single-photon emission computed tomography-computed tomography Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Immune checkpoint inhibitors in ovarian cancer:where do we go from here?

引用

Cancer Drug Resistance 2023年第2期6卷 358-377页

作者： Won-hee yoon Anna DeFazio Lawrence Kasherman Department of Medical Oncology Blacktown Cancer and Haematology CentreBlacktown HospitalBlacktown 2148Australia Department of Medical Oncology Crown Princess Mary Cancer CentreWestmead HospitalWestmead 2145Australia Centre for Cancer Research The Westmead Institute for Medical ResearchWestmead 2145Australia Faculty of Medicine and Health The University of SydneyCamperdown 2050Australia Department of Gynecological Oncology Westmead HospitalWestmead 2145Australia The Daffodil Centre The University of Sydneya joint venture with Cancer Council New South WalesSydney 2011Australia Department of Medical Oncology Illawarra Cancer Care CentreWollongong 2500Australia

Epithelial ovarian cancer(EOC)is the most lethal gynaecological malignancy,and despite advancements in therapeutics,most women unfortunately still succumb to their ***,in particular immune checkpoint inhibitors(ICI),have been therapeutically transformative in many tumour types,including gynaecological malignancies such as cervical and endometrial ***,these therapeutic successes have not been mirrored in ovarian cancer clinical *** review provides an overview of the ovarian tumour microenvironment(TME),particularly factors associated with survival,and explores current research into immunotherapeutic strategies in EOC,with an exploratory focus on novel therapeutics in navigating drug resistance.

关键词： Ovarian cancer immunotherapy tumour microenvironment drug development

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Texture development and grain boundary phase formation in Ce-and Ce-La-substituted Nd-Fe-B magnets during hot-deformation process

引用

Journal of Materials Science & Technology 2022年第31期126卷 71-79页

作者： Ga-Yeong Kim Tae-Hoon Kim hee-Ryoung cha Sang-hyub Lee Dong-Hwan Kim Yang-Do Kim Jung-Goo Lee Department of Magnetic Materials Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Engineering Pusan National UniversityBusan 46241Republic of Korea R&D Center Star Group Ind.Co.Ltd.Daegu 42714Republic of Korea

In this study,the influence of Ce-and Ce-La-substitution for Nd in Nd-Fe-B magnets on their magnetic and microstructural changes in the course of the hot-deformation process was investigated to gain insight into further reducing the Nd content in fine-grained Nd-Fe-B hot-deformed *** found that the[001]texture and microstructure of the RE-rich grain boundary phases,which are the factors that de-termine the remanence and coercivity of hot-deformed magnets,were deteriorated by the Ce-and *** is because the volume fraction of the RE-rich liquid formed in the grain boundaries during the hot-press and hot-deformation decreased due to the Ce-and Ce-La-substitution,thereby in-creasing the friction between the 2:14:1 grains while the c-axes of grains were aligned by grain rotation and decreasing the RE concentration of grain boundary *** particular,the Ce-La-co-substitution further prevented the liquid formation within the grain boundaries of the magnets during hot-press and hot-deformation because the wettability of the RE-rich liquid on the 2:14:1 grains became poor when La was substituted for Nd in the 2:14:1 *** results indicate that there is room for further im-provement in both the remanence and coercivity of the Ce-and Ce-La-substituted magnets by intro-ducing additional liquid into the grain boundaries prior to hot-press and *** applying the Nd-Cu infiltration process to the melt-spun ribbons(intermediate infiltration,I-infiltration),both the remanence and coercivity of the Nd-saving(Nd 0.7 Ce 0.3)-Fe-B and(Nd 0.7 Ce 0.225 La 0.075)-Fe-B hot-deformed magnets were successfully improved.

关键词： Nd-Fe-B magnets Hot-deformation Nd-saving Ce-substitution La-substitution Infiltration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tyrosine-mediated analog resistive switching for artificial neural networks

引用

Nano Research 2023年第1期16卷 858-864页

作者： Min-Kyu Song Seok Daniel Namgung Hojung Lee Jeong Hyun yoon Young-Woong Song Kang hee Cho yoon-Sik Lee Jong-Seok Lee Ki Tae Nam Jang-Yeon Kwon School of Integrated Technology Yonsei UniversityIncheon 21983Republic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyMA 02139USA Research Laboratory of Electronics Massachusetts Institute of TechnologyMA 02139USA Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Soft Foundry Seoul National UniversitySeoul 08826Republic of Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea

The fourth industrial revolution indispensably brings explosive data processing and storage;thus,a new computing paradigm based on artificial intelligence-enabling device structure is urgently *** have received considerable attention in this regard because of their ability to process and store data at the same ***,fundamental problems with abrupt switching characteristics limit their practical *** address this problem,we utilized the concept of metaplasticity inspired by biosystems and observed gradual switching in the peptide-based memristor at high proton *** unexpectedly high slope value>1.7 in the logI–V curve at low voltage(≤400 mV)was considered the main origin,and it might arise from the modulatory response of proton ions on the threshold of Ag ion migration in the peptide *** the obtained gradual switching property at high proton conductivity,the device showed significantly increased accuracy of image recognition(~82.5%).We believe that such a demonstration not only contributes to the practical application of neuromorphic devices but also expands the bioinspired functional synthetic platform.

关键词： artificial synapse neuromorphic computing proton conductor peptide materials artificial neural network

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：