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Food Bioscience 2023年第1期51卷 490-497页

作者： Ye-eun lee Yu-Ra Kang yoon Hyuk Chang Department of Food and Nutrition And Bionanocomposite Research CenterKyung Hee UniversitySeoul02447South Korea

The present study was carried out to evaluate the effects of different concentrations of pectic oligosaccharide(POS)on the physicochemical properties of Lactobacillus bulgaricus(***)loaded-synbiotic hydrogel beads and the survival of *** methoxyl(LM)pectin-resistant starch(RS)hydrogel beads,named RS beads,were coated/filled with different concentrations of POS:0.8%(RS-POS0.8 beads),1.0%(RS-POS1.0 beads),and 1.2%(RS-POS1.2 beads).POS treatment resulted in smooth beads with less surface dent by hydrogen bonding between RS beads and POS,which was confirmed by SEM and XRD *** encapsulation efficiency of RS beads and RS-POS beads ranged from 90.40%to 92.03%.In simulated gastric fluid(SGF)and bile salt solution,free *** completely died but *** encapsulated in RS-POS1.2 beads only slightly *** indicates that RS-POS1.2 beads exhibited higher protective effects on *** under SGF condition and bile ***,considering the relatively higher storage stability of *** loaded in RS-POS1.2 beads,the present results suggest that RS beads coated/filled with POS could be used for synbiotic encapsulation,protection,and delivery of probiotics.

关键词： Pectic oligosaccharide Synbiotic encapsulation Hydrogel bead Probiotic

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Journal of Central South University 2014年第9期21卷 3534-3540页

作者： lee Sang-hyuk YAN Sun JEONG yoon-su SHIN Seung-soo Department of Electrical and Electronic Engineering Xi'an Jiaotong-Liverpool University International Business School Suzhou Xi'an Jiaotong-Liverpool University Department of Information Communication Engineering Mokwon University Department of Information Security Tongmyong University

Information analysis of high dimensional data was carried out through similarity measure application. High dimensional data were considered as the a typical structure. Additionally, overlapped and non-overlapped data were introduced, and similarity measure analysis was also illustrated and compared with conventional similarity measure. As a result, overlapped data comparison was possible to present similarity with conventional similarity measure. Non-overlapped data similarity analysis provided the clue to solve the similarity of high dimensional data. Considering high dimensional data analysis was designed with consideration of neighborhoods information. Conservative and strict solutions were proposed. Proposed similarity measure was applied to express financial fraud among multi dimensional datasets. In illustrative example, financial fraud similarity with respect to age, gender, qualification and job was presented. And with the proposed similarity measure, high dimensional personal data were calculated to evaluate how similar to the financial fraud. Calculation results show that the actual fraud has rather high similarity measure compared to the average, from minimal 0.0609 to maximal 0.1667.

关键词： high dimensional data similarity measure difference neighborhood information financial fraud

Will the collaboration of surgery and external radiotherapy open new avenues for hepatocellular carcinoma with portal vein thrombosis?

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World Journal of Gastroenterology 2022年第7期28卷 704-714页

作者： Jung Wan Choe Hye yoon lee Chai Hong Rim Department ofInternal Medicine Korea University Ansan HospitalAnsan 15355South Korea Department of Surgery Korea University Ansan HospitalAnsan 15355South Korea Department of Radiation Oncology Korea University Ansan HospitalAnsan 15355South Korea

Portal invasion of hepatocellular carcinoma(HCC)occurs in 12.5%-40%of patients diagnosed with cancer and yields poor clinical *** it is a common cause of inoperability,sorafenib was regarded as the standard treatment for HCC in the Barcelona Clinic of Liver Cancer ***,the median survival of the Asian population was only approximately 6 mo,and the tumor response rate was less than moderate(<5%).Various locoregional modalities were performed,including external beam radiotherapy(EBRT),transarterial chemoembolization,hepatic arterial infusion chemotherapy,and surgery,alone or in *** them,EBRT is a noninvasive method and can safely treat tumors involving the major *** EBRT has been commonly performed,especially in East Asian countries,where locally invasive HCC is highly *** surgery is not commonly indicated,pioneering studies have demonstrated encouraging results in recent ***,the combination of neo-or adjuvant EBRT and surgery has been recently used and has significantly improved the outcomes of HCC patients,as reported in a few randomized *** systemic modality,a combination of novel immunotherapy and vascular endothelial growth factor inhibitor showed results superior to that of sorafenib as a first-line *** clinical trials investigating the combined use of these novel agents,surgery,and EBRT are expected to improve the prognosis of HCC with portal invasion.

关键词： Surgery Hepatocellular carcinoma Radiotherapy Systemic treatment

Endoscopic management of occluded metal biliary stents:Metal versus 10F plastic stents

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World Journal of Gastroenterology 2010年第42期16卷 5347-5352页

作者： Won Jae yoon Ji Kon Ryu Jung Won lee Dong-Won Ahn Yong-Tae Kim Yong Bum yoon Sang Myung Woo Woo Jin lee Division of Gastroenterology Department of Internal MedicineSeoul National University College of Medicine101 Daehang-roJongno-guSeoul110-744South Korea Center for Liver Cancer National Cancer Center323 Ilsan-roIlsandong-guGoyang-siGyeonggi-do410-769South Korea

AIM:To compare the efficacy of self-expandable metal stents(SEMSs) with 10F plastic stents(PSs) in the endoscopic management of occluded ***:We retrospectively reviewed the medical records of 56 patients who underwent SEMS insertion for palliation of unresectable malignant biliary obstruction between 2000 and 2007 and subsequent endoscopic retrograde biliary drainage(ERBD) with SEMS or PS for initial SEMS occlusion between 2000 and ***:Subsequent ERBD with SEMS was performed in 29 patients and with PS in *** median time to stent occlusion after subsequent ERBD was 186 d in the SEMS group and 101 d in the PS group(P= 0.118).Overall median stent patency was 79 d for the SEMS group and 66 d for the PS group(P = 0.379).The mean number of additional biliary drainage procedures after subsequent ERBD in patients that died(n = 50) during the study period was 2.54 ± 4.12 for the SEMS group and 1.85 ± 1.95 for the PS group(P = 0.457).The mean total cost of additional biliary drainage procedures after the occlusion of subsequent SEMS or PS was $410.04 ± 692.60 for the SEMS group and $630.16 ± 671.63 for the PS group(P = 0.260).Tumor ingrowth as the cause of initial SEMS occlusion was the only factor associated with a shorter time to subsequent stent occlusion(101 d for patients with tumor ingrowth vs 268 d for patients without tumor ingrowth,P = 0.008).CONCLUSION:Subsequent ERBD with PSs offered similar patency and number of additional biliary drainage procedures compared to SEMSs in the management of occluded SEMS.

关键词： Stents Biliary tract neoplasms Obstructive jaundice Endoscopy Endoscopic retrograde cholangiopancreatography

Numerical Visualization of Air Intake Induced by Free Surface Vortex

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Journal of Thermal Science 2017年第6期26卷 540-544页

作者： Young Kyu Park Mohan Kumar Dey yoon Hwan Choi Yeon Won lee Research Institute of Industrial Science & Technology Pukyong National University Busan Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Korea Department of Mechanical Design Engineering Pukyong National University Busan Korea

Free surface vortex control is vital in a pump sump system because the air absorbed by free surface vortex induc- es noise, vibration, and cavitation corrosion on the pumping system. In this study, the change of free surface vor- tex and air absorption in a pump intake has been investigated by the Volume of Fraction （VOF） method with steady multiphase flow model in order to represent the behavior of the free surface vortex exactly. The homoge- neous free surface model is used to apply interactions of air and water. The results show that air intake by the free surface vortex motion can be visualized using the iso-surface of air volume fraction. The vortices make an air column from the free surface to the pump intake. Also, it was found that the flee surface vortex can be controlled by installing curtain walls.

关键词： free surface vortex numerical visualization curtain wall air intake

Behavioral consequences of children with sleep-disordered breathing after adenotonsillectomy

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World Journal of Pediatrics 2018年第1期14卷 57-65页

作者： Ji yoon Kim Chang Ho lee Hyoung-Mi Kim Otorhinolaryngology Department CHA UniversitySeongnamKorea Otorhinolaryngology Department CHA Bundang MedicalCenterCHA University351Yatap-dongBundang-guSeongnam-siGyeonggi-do463-712Korea

Background Adenotonsillectomy (AT) has been an effective treatment for sleep-disordered breathing (SDB) in children, and several studies described the risk of postoperative weight gain and obesity in children treated with AT. The present study aimed to evaluate behavioral improvements in children with SDB one year after adenotonsillectomy and to investigate an influence of postoperative weight gain on behaviors. Methods The study included 170 children aged 5–11 years who underwent adenotonsillectomy for SDB and 150 controls. Body mass index percentile was obtained for age and gender, and parental sleep-related breathing disorder (SRBD) question-naire was used to assess the severity of SDB. Psychological assessment was performed pre- and post-adenotonsillectomy using standardized questionnaires including strength and difficulties questionnaire, children's depression inventory and screen for child anxiety-related emotional disorder. Results The mean age of 170 patients was 7.7 ± 1.5 years with 73 (42.9%) girls and 97 (57.1%) boys. The mean follow-up period were 15.4 ± 2.7 months. The patients had shown significant improvements in SDB scores as well as in questionnaire-based behavioral problems after adenotonsillectomy. The odds of a child being overweight were significantly increased after adenotonsillectomy. Less improvements in hyperactivity and conduct problems were observed in the patients with older ages, higher SRBD scores, and overweight/obesity at 1-year follow-up after adenotonsillectomy. Conclusion These data suggest that abnormal behavioral outcomes should be evaluated postoperatively, which potentially could be reduced with the early adenotonsillectomy and adequate postoperative weight control.

关键词： Obesity Obstructive sleep apnea Pediatric Snoring Tonsillectomy

Monitoring of non-point source pollutants load from a mixed forest land use

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Journal of Environmental Sciences 2010年第6期22卷 801-805页

作者： Sung Wan yoon Se Woong Chung Dong Geun Oh Jae Woon lee Department of Environmental Engineering Chungbuk National University Geum River Environmental Research Center National Institute of Environmental Research

The aim of this study was to determine the unit load of NPS （non-point source） pollutants including organic variables such as BOD （biochemical oxygen demand）, COD （chemical oxygen demand） and DOC （dissolved organic carbon）, nitrogen and phosphorus constituents, and suspended solids （SS） and their event mean concentration （EMC） of runoff flows from a water-shed of mixed forest land use by intensive field experiments. Field monitoring for continuous measurements of rainfall, flow, and water quality was conducted over 12 storm events during 2008-2009 using automated and manual sampling methods. The EMCs of individual runoff event were estimated for each water quality constituent based on the flow rate and concentration data of runoff discharge. The average EMCs of BOD, COD, DOC, SS, TN （total nitrogen）, NH4^＋-N, NO3^--N, TP （total phosphorus）, PO4^3-P from the mixed forest land were 1.794, 3.498, 1.462, 10.269, 0.862, 0.044, 0.634, 0.034, and 0.005 mg/L, respectively. The annual unit loads of BOD, COD, DOC, SS, TN, NH4^＋-N, NO3^--N, TP and PO4^3--P were estimated as 66.9, 133.2, 55.5, 429.8, 36.5, 1.6, 26.9, 1.3 and 0.1 kg/（ha·yr）, respectively. In addition, affecting parameters on the EMCs were investigated by statistic analysis of the field data. As a result, significant correlations with precipitation, rainfall intensity, and total runoff flows were found in most constituents.

关键词： event mean concentration mixed forest land use non-point source pollutant load unit load

Performance Analyses for a Cyclone Type Filter

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Journal of Thermal Science 2015年第3期24卷 290-294页

作者： Hyoung-June Kim Masahiro Takei Hyun Jin lee Yeon Won lee yoon Hwan Choi Deog-Hee Doh School of Mechanical Engineering Artificial Science Division Chiba University Division of Mech. and Energy Systems Eng. Korea Maritime University Dept. of Mechanical and Automotive Engineering Pukyong National University

Flow characteristics inside a cyclone filter were investigated by the use of computational fluid dynamics(CFD). For computations, SST model was adopted. Parametric study was carried out considering the filtering performance. Revolution speeds were changed from 100 to 550 with 50 increments. A skirt is the driving source for cyclone operation. The influence of several design factors, such as the skirt length, the skirt gap and the return length to filtering performance was investigated under the particle diameter 100μm of debris material(Al, s.g.=2.7). The filtering performance was also investigated with the skirt length 28 mm changing the debris diameters from 1μm to 50μm. The flow rate of the working fluid was maintained at 0.55kg/s. It has been verified that the most influential factors to the filtering efficiencies was the skirt gap between the cyclone generator and the cyclone vessel.

关键词： CFD cyclone filter design factors filtering performances

Quantum-dot and organic hybrid light-emitting diodes employing a blue common layer for simple fabrication of full-color displays

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Nano Research 2022年第7期15卷 6477-6482页

作者： Suhyeon lee Donghyo Hahm Suk-Young yoon Heesun Yang Wan Ki Bae Jeonghun Kwak Department of Electrical and Computer Engineering Seoul National UniversitySeoul 08826Republic of Korea Inter-university Semiconductor Research Center(ISRC) Seoul National UniversitySeoul 08826Republic of Korea SKKU Advanced Institute of Nanotechnology(SAINT) School of Nano Science&TechnologySungkyunkwan University(SKKU)Suwon 16419Republic of Korea Department of Materials Science and Engineering Hongik UniversitySeoul 04066Republic of Korea

Colloidal quantum-dot(QD)light-emitting diodes(QLEDs)have been in the forefront of future display devices due to their outstanding optoelectronic ***,a complicated solution-process for patterning the red,green,and blue QDs deteriorates the QLED performance and limits the resolution of full-color ***,we report a novel concept of QD–organic hybrid light-emitting diodes by introducing an organic blue common layer(BCL)which is deposited through a common mask over the entire *** from the optimized device structure,red and green QLEDs retained their color coordinates despite the presence of the ***,adopting the BCL improved the external quantum efficiency of green and red QLEDs by 38.4%and 11.7%,respectively,due to the Förster resonance energy transfer from the BCL to the adjacent QD *** the BCL structure,we could simply demonstrate a full-color QD-organic hybrid device in a single *** believe that this device architecture is practically applicable for easier fabrication of solution-processed,highresolution,and full-color displays with reduced process steps.

关键词： quantum-dot light-emitting diode(QLEDs) organic light-emitting diode blue common layer full-color display reduced process step

Postoperative adjuvant chemoradiotherapy in D2-dissected gastric cancer: Is radiotherapy necessary after D2-dissection?

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World Journal of Gastroenterology 2014年第36期20卷 12900-12907页

作者： Jee Suk Chang Woong Sub Koom Youngin lee Hong In yoon Hyung Sik lee Department of Radiation Oncology Yonsei University College of Medicine Seoul 120-752 South Korea Department of Radiation Oncology Dong-A University Hospital Busan 602-715 South Korea

Studies from the Far East have demonstrated that D2-dissection is superior to D0/1-dissection. The effect of postoperative chemoradiotherapy(CRT) after D2-dissection has not been accepted due to the lack of D2-dissection in Western countries, as well as the potential harmful effect of radiotherapy. In the current NCCN guideline, adjuvant chemotherapy alone is recommended in D2-dissected patients. However, three recent prospective randomized controlled trials in South Korea and China(ARTIST, NCC and Multicenter IMRT Trials) demonstrated that adjuvant CRT can be safely administered to D2-dissected patients with notable benefits. To identify the role of radiotherapy(RT) in the D2-dissected postoperative setting, clinical research attempts should include(1) identification of high-risk patients for loco-regional recurrence who might benefit from CRT;(2) modification of RT target volume based on the findings that failure patterns should be different after D1- and D2-dissection; and(3) integration of new RT techniques to decrease treatment-related toxicity. The present paper is a review of recent studies addressing these fields. Well-designed prospective randomized studies are needed to clearly define the role of adjuvant CRT in D2-dissected gastric cancer, however, future clinical studies should also focus on answering these questions.

关键词： Gastric cancer D2-dissection Recurrence Radiotherapy Chemotherapy