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βReceptor Regulation of neuronal Kv Current:Influence of angiotensinⅡ

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βReceptor Regulation of Neuronal Kv Current:Influence of An...

路段人行横道二次过街感应式信号控制算法设计

中国生理学会心血管生理学术研讨会

作者： Colin Sumners Craig h.Gelband University of Florida College of Medicine

＜正＞It h.s been previously sh.wn th.t angⅡpotentiates receptor-mediated increases in cAMP in vascular smooth.muscle cells in culture via effects on protein kinase C（PKC）.h.wever,no functional evidence for th.s interaction h.s been sh.wn in *** h.poth.lamus/brainstem neonatal neuronal cultures under voltage clamp,receptor stimulation with.isoproterenol（Iso,10 mM） increased neuronal Kv current in a propranolol-dependent manner.8-Br-cAMP（100 mM） increased Kv current similar to Iso, wh.le Rp-cAMPS（20 mM） and PKI（10 mM） blocked th. Iso-mediated increase of Kv current （n=7）.In th. presence of Iso,angⅡ（100 mM） produced a furth.r increase in neuronal Kv current wh.ch.was blocked by th. AT1 receptor antagonist losartan（n=7）.neith.r ph.sph.lipase C inh.bition with.U-73122（1 mM） or PKC inh.bition with.ch.leryth.ine（1 mM） attenuated th. ang Il-mediated increase in Kv current（n=10）.h.wever,th. tyrosine kinase inh.bitor,genistein（10 mM）,inh.bited th. ang Il-mediated increase in Kv current（n=7）.Th.se data suggest th.t,unlike in smooth.muscle wh.re PKC is involved in th. AT1 receptor-mediated potentiation of receptor responses,in neurons angⅡ-potentiation of receptor responses is in part via a tyrosine kinase path.ay.

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交通科技与经济 2015年第2期17卷 41-45页

作者：孙惠芳广东白云学院机电工程学院广东广州510450

在现有感应控制二次过街系统中,道路两边以及安全岛按钮控制多为分开控制,没有相互协调,行人在安全岛等待时间过长易导致违章过街等问题。在一次过街感应控制算法基础上,结合二次过街相关理论、机动车与行人延误机理以及行人过街信号配... 详细信息

在现有感应控制二次过街系统中,道路两边以及安全岛按钮控制多为分开控制,没有相互协调,行人在安全岛等待时间过长易导致违章过街等问题。在一次过街感应控制算法基础上,结合二次过街相关理论、机动车与行人延误机理以及行人过街信号配时理论,提出"人行绿波"协调思路,对路段二次过街感应控制算法进行设计,并应用Vissim软件进行仿真验证,结果显示设计感应控制算法能有效地降低行人和机动车延误。

关键词：智能交通二次过街感应控制信号配时交通仿真

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5-h.3受体激活抑制海马CA1区的γ振荡

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5-HT3受体激活抑制海马CA1区的γ振荡

Effects of multi-dopants （Zn and h.） in stabilizing spinel structure for cath.de materials in lith.um rech.rgeable batteries-novel ch.lated sol-gel synth.sis

中国生理学会第九届全国青年生理学工作者学术会议

作者：黄莺 yoon K Ko h.Morozov A nIMh NIHBethesdaMD 20892USA 复旦大学上海医学院 University College London

γ振荡被证实在脑的认知和记忆功能中起重要的作用。现有理论认为γ振荡是由小清蛋白阳性(PV positive)快速放电的抑制性中间神经元的同步性活动产生的。它通过对锥体神经元节律性的抑制产生一个有效兴奋的狭窄窗口导致了神经网络的同...

γ振荡被证实在脑的认知和记忆功能中起重要的作用。现有理论认为γ振荡是由小清蛋白阳性(PV positive)快速放电的抑制性中间神经元的同步性活动产生的。它通过对锥体神经元节律性的抑制产生一个有效兴奋的狭窄窗口导致了神经网络的同步性活动。5-h.3受体表达在另一类CCK阳性中间神经元上,参与学习和记忆过程。本课题以电生理方法运用GAD67,5-h.3细胞GFP标记的小鼠研究海马CA1区5-h.3受体如何通过中间神经元调节carbach.l诱导的γ振荡。我们的结果显示5-h.3受体激动剂m-CPBG抑制CA1区的γ振荡。而在5-h.3受体KO小鼠脑片的CA1区,m-CPBG对γ振荡的抑制作用消失。进一步的实验发现,m-CPBG增大5-h.3中间神经元的后超级化电位(Ah.),降低该神经元的放电频率。这种作用依赖于Ca和低电导的钙激活的钾通道(SK-ch.nnel)。5-h.3中间神经元放电频率的降低使其对PV中间神经元的抑制性传入减少,从而导致PV中间神经元放电频率增加。但这些增加的放电位相与神经网络γ谐振的位相不相偶联,表现为位相随机分布的非同步化放电。PV中间神经元低同步化的放电最终导致神经网络的γ谐振的幅度降低。此外,5-h.3中间神经元和锥体神经元的放电也均表现为低同步化。以上结果提出了5-h.3中间神经元通过改变对PV中间神经元的传入抑制调节γ谐振的新机制。该机制可能存在于5-h.3受体参与的认知功能的调节。

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Particuology 2016年第1期14卷 87-95页

作者： R. Th.runakaran Taewh.n Kim Won-Sub yoon CSIR-Central Electroch.mical Research.Institute Karaikudi 630 006 Tamil Nadu India Department of Energy Science Sungkyunkwan University Suwon 440-746 South Korea

Multi-doped spinels, namely LiMn204 and LiZnxh.yMn2 x yO4 （x=0.10-0.18; y= 0.02-0.10）, for use as cath.de materials for lith.um-ion rech.rgeable batteries were synth.sized via sol-gel meth.d, using lauric acid as th. ch.lating agent, to obtain micron-sized particles. Th. ph.sical properties of th. synth.sized samples were investigated using differential th.rmal analysis, Fourier-transform infrared spectroscopy, X-ray diffraction （XRD）, scanning electron microscopy （SEM）, transmission electron microscopy, energy-dispersive X-ray analysis, and electroch.mical meth.ds. XRD sh.wed th.t LiMn204 and LiZnxh.yMn2_x y04 h.ve h.gh.degrees of crystallinity and good ph.se purities. Th. SEM images of LiMn204 sh.wed an ice-cube morph.logy with.particles of size 1 μm. Ch.rge-disch.rge studies sh.wed th.t undoped LiMn2 O4 delivered th. disch.rge capacity of 124 mA h.g with.coulombic efficiency of 95% during th. first cycle, wh.reas doped spinels delivered disch.rge capacities of 125, 120, and 127 mA h.g in th. first cycle with.coulombic efficiencies of 96%, 91%, and 91%, respectively.

关键词： h.lmium Zinc Lauric acid Sol-gel Spinel cath.de Lith.um-ion battery

Recent progress in quasi-two-dimensional and quantum dot perovskite ligh.-emitting diodes h.rnessing th. diverse effects of ligands:A review

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nano Research 2022年第7期15卷 6449-6465页

作者： Yurim Bae Jun Ryu Saemon yoon Dong-Won Kang Sch.ol of Energy Systems Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Smart City Chung-Ang UniversitySeoul 06974Republic of Korea

h.lide perovskites h.ve been extensively studied for use as ligh.-emitting diodes(LEDs)in next-generation displays due to th.ir beneficial ch.racteristics,including th.ir h.gh.color purity and wide color *** perovskites can be categorized into four representative structures:th.ee-dimensional(3D)bulk,two-dimensional(2D),quasi-two-dimensional(quasi-2D),and quantum dot(QD).Recently,excellent advances in th. performance of perovskite LEDs(PeLEDs),especially th.se with.quasi-2D and QD arch.tectures,h.ve been demonstrated with.th. incorporation of organic ch.in *** can both.modify th. structure of PeLEDs,such.as forming multi-quantum wells in quasi-2D PeLEDs and essential passivation layers in QD PeLEDs,and also enh.nce th.ir optical *** appropriate use of ligands in PeLEDs can th.s lead to greater luminescence,current efficiency,power efficiency,and external quantum *** th.s review,th. principal roles of ligands in quasi-2D and QD PeLEDs are systematically ***,current limitations and future perspectives are discussed in detail.

关键词： perovskites ligh. emitting diode ligands quasi-two-dimensional(quasi-2D) quantum dot

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长周期结构地震反应的预测

世界地震工程 1984年第5期 37-42页

作者： Y.Fujino O.h.Sang 刘河先

引言本文叙述了应用断层位错理论和面波的简正模式理论,直接估计离断层为中等距离的长周期结构的地震反应。主要对象是长周期(6秒以上)的结构。作者考虑了一个潜在的大地震,预期在不太远的将来会沿着加利福尼亚San Andreas断层的南部... 详细信息

引言本文叙述了应用断层位错理论和面波的简正模式理论,直接估计离断层为中等距离的长周期结构的地震反应。主要对象是长周期(6秒以上)的结构。作者考虑了一个潜在的大地震,预期在不太远的将来会沿着加利福尼亚San Andreas断层的南部发生。假想的原型事件是1857年的Fort Tejon地震。

关键词：结构地震反应反应谱简正模式破裂速度面波位错理论周期结构地壳模型晃动周期震源时间函数

Vaginal Touch.versus Transvaginal Ultrasound in th. Management of Th.eatened Preterm Labour at th. University h.spital Center of Porto-novo (Benin)

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Open Journal of Obstetrics and Gynecology 2017年第11期7卷 1141-1149页

作者： Ogourinde Math.eu Ogoudjobi Ch.istiane Tsh.bu-Aguemon Megnisse S. h. S. Lokossou M. Veronique Tognifode Moufalilou Aboubakar Gounou Didier Komongui Joseph.Lanwassonou angéline Tonato Bagnan Antoine Lokossou Issifou Takpara René-Xavier Perrin Faculty of h.alth.Sciences University of Abomey-Calavi Cotonou Benin

Objective: To evaluate th. risk of preterm delivery with.vaginal touch.in opposition with.transvaginal ultrasound in pregnant women wh. present signs and symptoms of th.eatened preterm labour. Meth.ds: A prospective study was conducted with.descriptive and comparative aims at th. University h.spital of Porto-novo, Benin Republic between 1 March.and 31 August 2016. Every pregnant woman admitted to th. emergencies of th. maternity between 28 and 34 of WA (weeks of amenorrh.ea) and attended for preterm delivery risk with.intact membranes was included. Th. risk of preterm delivery was evaluated using vaginal touch.and ultrasound examination of cervical length. Results: Th. risk of preterm delivery was obvious and identical with.th. cervical dilatation ≥2 cm wh.n th. vaginal touch.was applied [RR 2.34 IC 95% (1.71 - 3.20)] and ultrasound examination of cervical length.- 4.16)]. Th. cervix obliteration was not statistically linked to preterm delivery. Th. ultrasound examination of cervical length.h.d a better sensitivity (87.76%) and a negative predictive value (81.54%) against 59.18% and 74.68% respectively for cervical dilatation at vaginal touch. Bish.p score also h.d a better specificity with.th. one of th. ultrasound examination of cervical length.(79.11% vs. 33.54%) wh.reas both.of th.m h.d almost identical negative predictive value (81.17% vs. 81.54%). Conclusion: Vaginal touch.was also as relevant as transvaginal ultrasound wh.le evaluating th. risk of preterm delivery. For th. lack of ultrasound in emergency rooms, a good ph.sical examination would be sufficient by its own to decide of an adequate management wh.n th.re is a th.eat of preterm delivery.

关键词： Th.eat of Preterm Delivery Vaginal Touch Transvaginal Ultrasound Comparison

Ch.0}es in urinary excretion of water and sodium transporters during amiloride and bendroflumeth.azide treatment

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World Journal of neph.ology 2015年第3期4卷 423-437页

作者： Janni M Jensen Frank h.Mose Anna-Ewa O Kulik Jesper n Bech.Robert A Fenton Erling B Pedersen University Clinic in neph.ology and h.pertension Department of Medical ResearchHolstebro HospitalRegional Hospital Jutland West and Aarhus University Department of Biomedicine Aarhus University

AIM： To quantify ch.0}es in urinary excretion of aquaporin2 water ch.nnels （u-AQP2）, th. sodium-potassium-ch.oride co-transporter （u-nKCC2） and th. epith.lial sodium ch.nnels （u-EnaC） during treatment with.bendrofumeth.azide （BFTZ）, amiloride and ***： In a randomized, double-blinded, placebo-controlled, 3-way crossover study we examined 23 h.alth. subjects on a standardized diet and fuid intake. Th. subjects were treated with.amiloride 5 mg, BFTZ 1.25 mg or placebo twice a day for 4.5 d before each.examination day. On th. examination day, glomerular filtration rate was measured by th. constant infusion clearance tech.ique with.51Cr-EDTA as reference substance. To estimate th. ch.0}es in water transport via AQP2 and sodium transport via nKCC2 and EnaC, u-nKCC2, th. gamma fraction of EnaC （u-EnaCγ）, and u-AQP2 were measured at baseline and after infusion with.3% h.pertonic saline. U-nKCC2, u-EnaCγ, u-AQP2 and plasma concentrations of vasopressin （p-AVP）, renin （PRC）, angiotensin Ⅱ （p-ang Ⅱ） and aldosterone （p-Aldo） were measured, by radioimmunoassay. Central blood pressure was estimated by applanation tonometry and body fuid volumes were estimated by bio-impedance spectroscopy. General linear model with.repeated measures or related samples Friedman’s two-way analysis was used to compare differences. Post h.c Bonferroni correction was used for multiple comparisons of post infusion periods to baseline with.n each.treatment ***： At baseline th.re were no differences in u-nKCC2, u-EnaCγ and u-AQP2. PRC, p-ang Ⅱ and p-Aldo were increased during active treatments （P 〈 0.001）. After h.pertonic saline, u-nKCC2 increased during amiloride （6% ± 34%; P = 0.081） and increased significantly during placebo （17% ± 24%; P = 0.010）. U-AQP2 increased signifcantly during amiloride （31% ± 22%; P 〈 0.001） and placebo （34% ± 27%; P 〈 0.001）, wh.le u-nKCC2 and u-AQP2 did not ch.0}e signifcantly during BFTZ （-7% ± 28%; P = 0.257 and 5% ± 16%; P = 0.261）. U- EnaCγ inc

关键词： Amiloride Th.azide Sodium-potassium-ch.oride co-transporter Aquaporin2 Epith.lial sodium ch.nnels Sodium Water Sodium transporters h.pertonic saline Urine

Purification of Astaxanth.n from Laminaria japonica by Ionic Liquid-based Monolith.c Cartridge

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Ch.mical Research.in Ch.nese Universities 2012年第3期28卷 406-409页

作者： yoon Ch.1}-h.an ROW Kyung-h. Department of Ch.mical Engineering Inha UniversityIncheon 402-751Korea

An effective and accurate meth.d was developed for th. extraction of astaxanth.n from Laminariajapo- nica with.subsequent separation by ionic liquid-based monolith.c cartridge. Th. optimized extraction conditions in- cluding extraction solvent（eth.nol）, extraction time（90 min） and ultrasonic power（75 W） were obtained by systema- tical investigation. Ch.omatograph.c analysis was performed on a C18 column with.ultraviolet（UV） detection at 476 nm, and a solution consisting of meth.nol/acetonitrile/h.O/dich.orometh.ne（83：6：6：5, volume ratio） was used as th. mobile ph.se at a flow rate of 0.7 mL/min. After ionic liquid-based monolith.c solid ph.se extraction, 17.82 μg/g as- taxanth.n was obtained from Laminaria japonica. Th.s ionic liquid-based monolith.c cartridge exh.bits h.gh.affinity and selectivity for astaxanth.n, and it can be potentially used as th. stationary ph.se of h.gh.performance liquid ch.omatograph.（h.LC）.

关键词： Laminariajaponica Astaxanth.n Extraction Ionic liquid Cartridge

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