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Single port laparoscopic right hemicolectomy with D3 dissection for advanced colon cancer

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World Journal of Gastroenterology 2010年第2期16卷 275-278页

作者： Sung Il Choi Kil Yeon lee Sun Jin Park suk-Hwan lee Department of Surgery School of MedicineKyung Hee University#1 Hoegi-dong Dongdaemun-guSeoul 130-702 South Korea

We report the first case of single port laparoscopic right hemicolectomy for advanced colon *** abdominal 3 cm length incision was made via the umbilicus.A small wound retractor and a surgical glove were used as a single *** soft tissue anterior to the superior mesenteric vein was completely removed and D3 lymph node dissection was *** total operative time was 180 min with minimal blood loss (<50 mL).The size of the tumor was 5 cm×3 cm and its tumor stage was ***-nine lymph nodes were harvested and none were *** believe that single port surgery for colon cancer is a feasible and safe procedure with surgical results comparable to conventional laparoscopic procedures.

关键词： Single port laparoscopic surgery Colon cancer D3 lymph node dissection

Stroke Based Painterly Rendering with Mass Data through Auto Warping Generation

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Computer Modeling in Engineering & Sciences 2022年第3期130卷 1441-1457页

作者： Taemin lee Beomsik Kim Sanghyun Seo Kyunghyun yoon Davinci SW Education Institute Chung-Ang UniversitySeoul06974South Korea School of Computer Science and Engineering Chung-Ang UniversitySeoul06974South Korea College of Art&Technology Chung-Ang UniversityGyeonggi-do17546South Korea

Painting is done according to the artist’s *** most representative of the style is the texture and shape of the brush *** simulations allow the artist’s painting to be produced by taking this stroke and pasting it onto the *** is called stroke-based *** quality of the result depends on the number or quality of this stroke,since the stroke is taken to create the *** is not easy to render using a large amount of information,as there is a limit to having a stroke *** this work,we intend to produce rendering results using mass data that produces large amounts of strokes by expanding existing strokes through *** this,we have produced results that have higher quality than conventional ***,we also compare the correlation between the amount of data and the results.

关键词： Painterly rendering stroke based rendering image mass data stroke warping non-photorealistic rendering

PI3K/Akt/mTOR inhibitors in breast cancer

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Cancer Biology & Medicine 2015年第4期12卷 342-354页

作者： Joycelyn JX lee Kiley Loh yoon-Sim Yap Department of Medical Oncology National Cancer Center Singapore

Activation of the phosphoinositide 3 kinase(PI3K)/Akt/mammalian target of rapamycin(mTOR) pathway is common in breast cancer. There is preclinical data to support inhibition of the pathway, and phase Ⅰ to Ⅲ trials involving inhibitors of the pathway have been or are being conducted in solid tumors and breast cancer. Everolimus, an mTOR inhibitor, is currently approved for the treatment of hormone receptor(HR)-positive, human epidermal growth factor receptor 2(HER2)-negative breast cancer. In this review, we summarise the efficacy and toxicity findings from the randomised clinical trials, with simplified guidelines on the management of potential adverse effects. Education of healthcare professionals and patients is critical for safety and compliance. While there is some clinical evidence of activity of mTOR inhibition in HR-positive and HER2-positive breast cancers, the benefits may be more pronounced in selected subsets rather than in the overall population. Further development of predictive biomarkers will be useful in the selection of patients who will benefit from inhibition of the PI3K/Akt/mTOR(PAM) pathway.

关键词： Breast cancer phosphoinositide 3 kinase(PI3K)/Akt/ mammalian target of rapamycin(mTOR) everolimus

Energy efficient mechanism using flexible medium access control protocol for hybrid wireless sensor networks

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Journal of Central South University 2013年第8期20卷 2165-2174页

作者： SUN Ning JEONG yoon-su lee Sang-ho Department of Computer Science Chungbuk National University Department of Information Communication Engineering Mokwon University

Energy efficiency is a primary consideration in a wireless sensor network (WSN). This is also a major parameter when designing a medium access control (MAC) protocol for WSNs. Hierarchical clustering structure is regarded suitable for WSNs due to its good performance in energy conservation. In this work, an adequately flexible mechanism for clustering WSNs is designed, in which some creative or promotional metrics are utilized, such as cluster head selection algorithm, cluster optional reconstruction, interested data transmission, multiple path routing protocol. All these strategies were cooperated to maximize energy saving of whole system. An appropriate MAC protocol for this mechanism is proposed, by flexibly switching the status of diverse sensor nodes in different strategies. The simulation results show that the proposed MAC protocol is suitable for clustering WSNs and performs well in aspects of energy efficiency, flexibility and scalability.

关键词： MAC protocol energy conservation flexibility re-clustering wireless sensor network

Effects of casting speed on microstructure and segregation of electromagnetically stirred Aluminum alloy in continuous casting process

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Rare Metals 2006年第z2期25卷 118-123页

作者： lee Dock-Young KANG suk-Won CHO Duck-Ho KIM Ki-Bae Division of Materials Korea Institute of Science and Technology P.O. Box 131 Cheongryang Seoul 130-650 Korea Department of Applied Materials Engineering Hanbat National University Daejeon 305-719 Korea

Recently, a semi-solid metal processing has been acknowledged as a cost-effective technique to be able to manufacture high quality product for the transportation industry. In this study a hypo-eutectic Al alloy was fabricated by means of an electromagnetic stirrer in continuous casting process and the microstructural change during solidification due to a fluid flow by electromagnetic stirring was examined. Due to the forced fluid flow during solidification a dendritic phase of primary α phase of Al alloy was turned into a globular phase, which can make the Al alloy get a thixotropic behavior in the semi-solid region. In order to establish the quantitative relationship between microstructure and the process parameters, the morphology shape, a silicon distribution and a size of primary α phase were observed according to casting speed in continuous casting machine. The primary α phase was turned into the degenerate dendrites approaching a spherical configuration with increasing casting speed. The fine-grained and equiaxed microstructure appeared at higher casting speed. A segregation behavior of Si element was declined with increasing casting speed and a very uniform distribution of Si element was observed on the billet at a casting speed of 600 mm·min-1. A thickness of the solidifying shell of the billet was shortened with increasing the casting speed.

关键词： semi-solid slurry electromagnetic stirring casting speed segregation Al alloy

Curcumin-induced cell death depends on the level of autophagic flux in A172 and U87MG human glioblastoma cells

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Chinese Journal of Natural Medicines 2020年第2期18卷 114-122页

作者： lee Jong-Eun yoon Sung Sik lee Jae-Wook Moon Eun-Yi Department of Bioscience and Biotechnology Sejong UniversitySeoul 05006Republic of Korea

Glioblastoma is the deadliest neoplasm with the worst 5-year survival rate among all human *** promotes autophagic cell death or blocks the induction of apoptosis in eukaryotic ***,we investigated whether varying levels of autophagic flux in glioblastoma lead to different efficacies of curcumin treatment using U87 MG and A172 human glioblastoma *** number of LC3 puncta,the number of cells with LC3 puncta and the level of LC3 Ⅱ,Atg5 and Atg7 protein were higher in U87 MG cells compared with A172 *** the cells were incubated with curcumin for 24 or 48 h,the percentage of cell death was higher in A172 cells compared with U87 MG *** the level of LC3 was lower,that of curcumin-induced LC3 was higher,in A172 cells than in U87 MG *** relative increases in cell death and LC3-mediated autophagy were greater under serum starvation in A172 cells compared with U87 MG ***-induced A172 cell death was reduced by serum *** both types of cells were transfected with LC3-GFP,the percentage of cell death was higher in A172 cells than that in U87 MG *** together,the data demonstrate that curcumin-mediated tumor cell death is regulated by the basal level of autophagic flux in different glioblastoma *** suggests that prior to the use of various curcumin therapeutics,the level of basal or induced autophagic flux should be carefully examined in tumor cells for the best efficacy.

关键词： Glioblastoma A172 U87MG Autophagic flux Curcumin

Highly Flexible Fabrics/Epoxy Composites with Hybrid Carbon Nanofillers for Absorption-Dominated Electromagnetic Interference Shielding

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Nano-Micro Letters 2022年第11期14卷 307-323页

作者： Jong-Hoon lee yoon-Sub Kim Hea-Jin Ru Seul-Yi lee Soo-Jin Park Department of Chemistry Inha University100 InharoIncheon 22212Korea Korea Architecture Safety Testing and Research Institute(KASTI) 88 Gasan Digital 1-roSeoul 08590Korea

Epoxy-based nano-composites can be ideal electromagnetic interference(EMI)-shielding materials owing to their lightness,chemical inertness,and mechanical ***,poor conductivity and brittleness of the epoxy resin are challenges for fast-growing portable and flexible EMI-shielding applications,such as smart wristband,medical cloth,aerospace,and military *** this study,we explored hybrid nanofillers of single-walled carbon nanotubes(SWCNT)/reduced graphene oxide(rGO)as conductive inks and polyester fabrics(PFs)as a substrate for flexible EMI-shielding *** highest electrical conductivity and fracture toughness of the SWCNT/rGO/PF/epoxy composites were 30.2 S m^(−1)and 38.5 MPa m^(1/2),which are~270 and 65%enhancement over those of the composites without SWCNTs,*** mechanical durability was demonstrated by stable electrical conductivity retention during 1000 cycles of bending *** EMI-shielding effectiveness of~41 dB in the X-band frequency of 8.2-12.4 GHz with a thickness of 0.6 mm was obtained with an EM absorption-dominant behavior over a 0.7 absorption *** results are attributed to the hierarchical architecture of the macroscale PF skeleton and nanoscale SWCNT/rGO networks,leading to superior EMI-shielding *** believe that this approach provides highly flexible and robust EMI-shielding composites for next-generation wearable electronic devices.

关键词： Conductive polymer composites Fracture toughness Flexible composites Absorption-dominated electromagnetic interference shielding

Effects of land use change and water reuse options on urban water cycle

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Journal of Environmental Sciences 2010年第6期22卷 923-928页

作者： Jiho lee Gijung Pak Chulsang Yoo Sangdan Kim Jaeyoung yoon School of Civil Environmentaland Architectural EngineeringKorea University Department of Environmental Engineering Korea University Department of Environmental System Engineering Pukyong National University

The aim of this article was to study the effects of land use change and water reuse options on an urban water cycle. A water cycle analysis was performed on the Goonja drainage basin, located in metropolitan Seoul, using the Aquacycle model. The chronological effects of urbanization were first assessed for the land uses of the Goonja drainage basin from 1975 to 2005, where the ratio of impervious areas ranged from 43% to 84%. Progressive urbanization was identified as leading to a decrease in evapotranspiration （29%）, an increase in surface runoff （41%） and a decrease in groundwater recharge （74%）, indicating a serious distortion of the water cycle. From a subsequent analysis of the water reuse options, such as rainwater use and wastewater reuse, it is concluded that wastewater reuse seemed to have an advantage over rainwater use for providing a consistent water supply throughout the year for a country like Korea. where the rainy season is concentrated during the summer monsoon.

关键词： Aquacycle model land use change water reuse

Tyrosine-mediated analog resistive switching for artificial neural networks

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Nano Research 2023年第1期16卷 858-864页

作者： Min-Kyu Song Seok Daniel Namgung Hojung lee Jeong Hyun yoon Young-Woong Song Kang Hee Cho yoon-Sik lee Jong-Seok lee Ki Tae Nam Jang-Yeon Kwon School of Integrated Technology Yonsei UniversityIncheon 21983Republic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyMA 02139USA Research Laboratory of Electronics Massachusetts Institute of TechnologyMA 02139USA Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Soft Foundry Seoul National UniversitySeoul 08826Republic of Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea

The fourth industrial revolution indispensably brings explosive data processing and storage;thus,a new computing paradigm based on artificial intelligence-enabling device structure is urgently *** have received considerable attention in this regard because of their ability to process and store data at the same ***,fundamental problems with abrupt switching characteristics limit their practical *** address this problem,we utilized the concept of metaplasticity inspired by biosystems and observed gradual switching in the peptide-based memristor at high proton *** unexpectedly high slope value>1.7 in the logI–V curve at low voltage(≤400 mV)was considered the main origin,and it might arise from the modulatory response of proton ions on the threshold of Ag ion migration in the peptide *** the obtained gradual switching property at high proton conductivity,the device showed significantly increased accuracy of image recognition(~82.5%).We believe that such a demonstration not only contributes to the practical application of neuromorphic devices but also expands the bioinspired functional synthetic platform.

关键词： artificial synapse neuromorphic computing proton conductor peptide materials artificial neural network