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Analyze the Performance of Electroactive Anticorrosion Coating of Medical Magnesium Alloy Using Deep Learning

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Computers, Materials & Continua 2024年第4期79卷 263-278页

作者： Yashan Feng Yafang Tian yongxin Yang Yufang Zhang Haiwei guo Jing’an Li Advanced Functional Materials Laboratory Zhengzhou Railway Vocational and Technical CollegeZhengzhou450000China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou450000China

Electroactive anticorrosion coatings are specialized surface treatments that prevent or minimize corrosion. Thestudy employs strategic thermodynamic equilibriumcalculations to pioneer a novel factor in corrosion protection.A first-time proposal, the total acidity (TA) potential of the hydrogen (pH) concept significantly shapes medicalmagnesium alloys. These coatings are meticulously designed for robust corrosion resistance, blending theoreticalinsights and practical applications to enhance our grasp of corrosion prevention mechanisms and establisha systematic approach to coating design. The groundbreaking significance of this study lies in its innovativeintegration of the TA/pH concept,which encompasses the TA/pH ratio of the chemical environment. This approachsurpasses convention by acknowledging the intricate interplay between the acidity and pH levels within thecoating formulation, thereby optimizing metal-phosphate-based conversion coatings and transforming corrosionmitigation strategies. To authenticate the TA/pH concept, the study comprehensively compares its findings withexisting research, rigorously validating the theoretical framework and reinforcing the correlates among TA/pHvalues and observed corrosion resistance in the coatings. The influence of mutations that occur naturally inthe detergent solution on persistent phosphorus changes is shown by empirical confirmation, which improvescorrosion resistance. This realization advances the field ofmaterials and the field’s knowledge of coated generation,particularly anticorrosion converter layers.

关键词： Medical magnesium alloys hydrogen gas anticorrosion total acidity potential of the hydrogen(pH)

Optimal Design of Aperture Illuminations for Microwave Power Transmission with Annular Collection Areas

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Engineering 2023年第11期30卷 63-74页

作者： Xun Li Baoyan Duan Yiqun Zhang yongxin guo Shaanxi Key Laboratory of Space Solar Power Station System Xidian UniversityXi’an 710071China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117576Singapore

This work presents an optimal design method of antenna aperture illumination for microwave power transmission with an annular collection area.The objective is to maximize the ratio of the power radiated on the annular collection area to the total transmitted power.By formulating the aperture amplitude distribution through a summation of a special set of series,the optimal design problem can be reduced to finding the maximum ratio of two real quadratic forms.Based on the theory of matrices,the solution to the formulated optimization problem is to determine the largest characteristic value and its associated characteristic vector.To meet security requirements,the peak radiation levels outside the receiving area are considered to be extra constraints.A hybrid grey wolf optimizer and Nelder–Mead simplex method is developed to deal with this constrained optimization problem.In order to demonstrate the effectiveness of the proposed method,numerical experiments on continuous apertures are conducted;then,discrete arrays of isotropic elements are employed to validate the correctness of the optimized results.Finally,patch arrays are adopted to further verify the validity of the proposed method.

关键词： Microwave power transmission Beam collection efficiency Ring-shaped beam Annular collection area Grey wolf optimizer Nelder-Mead simplex method

Fluorogenic sensing of amorphous aggregates,amyloid fibers,and chaperone activity via a near-infrared aggregation-induced emission-active probe

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Aggregate

Aggregate 2024年第1期5卷 309-320页

作者： Wei He Yuanyuan Yang Yuhui Qian Zhuoyi Chen yongxin Zheng Wenping Zhao Chenxu Yan Zhiqian guo Shu Quan State Key Laboratory of Bioreactor Engineering Shanghai Collaborative Innovation Center for Biomanufacturing(SCICB)East China University of Science and TechnologyShanghaiChina Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Shanghai Key Laboratory of Functional Materials ChemistryFrontiers Science Center for Materiobiology and Dynamic ChemistryInstitute of Fine ChemicalsSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghaiChina Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism East China University of Science and TechnologyShanghaiChina

The presence of protein aggregates in numerous human diseases underscores the significance of detecting these aggregates to comprehend disease mechanisms and develop novel therapeutic approaches for combating these disorders.Despite the development of various biosensors and fluorescent probes that selectively target amyloid fibers or amorphous aggregates,there is still a lack of tools capable of simultaneously detecting both types of aggregates.Herein,we demonstrate the quantitative discernment of amorphous aggregates by QM-FN-SO3,an aggregationinduced emission(AIE)probe initially designed for detecting amyloid fibers.This probe easily penetrates the membranes of the widely-used prokaryotic model organism Escherichia coli,enabling the visualization of both amorphous aggregates and amyloid fibers through near-infrared fluorescence.Notably,the probe exhibits sensitivity in distinguishing the varying aggregation propensities of proteins,regardless of whether they form amorphous aggregates or amyloid fibers in vivo.These properties contribute to the successful application of the QM-FN-SO3 probe in the subsequent investigation of the antiaggregation activities of two outer membrane protein(OMP)chaperones,both in vitro and in their physiological environment.Overall,our work introduces a near-infrared fluorescent chemical probe that can quantitatively detect amyloid fibers and amorphous aggregates with high sensitivity in vitro and in vivo.Furthermore,it demonstrates the applicability of the probe in chaperone biology and its potential as a high-throughput screening tool for protein aggregation inhibitors and folding factors.

关键词： aggregation-induced emission fluorescence molecular chaperone protein aggregation

Scavenging Microwave Wireless Power:A Unified Model,Rectenna Design Automation,and Cutting-Edge Techniques

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Engineering 2023年第11期30卷 32-48页

作者： Si-Ping Gao Jun-Hui Ou Xiuyin Zhang yongxin guo Department of Electrical and Computer Engineering National University of SingaporeSingapore 117576Singapore School of Electronic and Information Engineering South China University of TechnologyGuangzhou 510641China School of Future Technology South China University of TechnologyGuangzhou 511442China

While sufficient review articles exist on inductive short-range wireless power transfer(WPT),long-haul microwave WPT(MWPT)for solar power satellites,and ambient microwave wireless energy harvesting(MWEH)in urban areas,few studies focus on the fundamental modeling and related design automation of receiver systems.This article reviews the development of MWPT and MWEH receivers,with a focus on rectenna design automation.A novel rectifier model capable of accurately modeling the rectification process under both high and low input power is presented.The model reveals the theoretical boundary of radio frequency-to-direct current(dc)power conversion efficiency and,most importantly,enables an automated system design.The automated rectenna design flow is sequential,with the minimal engagement of iterative optimization.It covers the design automation of every module(i.e.,rectifiers,matching circuits,antennae,and dc–dc converters).Scaling-up of the technique to large rectenna arrays is also possible,where the challenges in array partitioning and power combining are briefly discussed.In addition,several cutting-edge rectenna techniques for MWPT and MWEH are reviewed,including the dynamic range extension technique,the harmonics-based retro-directive technique,and the simultaneous wireless information and power transfer technique,which can be good complements to the presented automated design methodology.

关键词： Microwave wireless power transfer Microwave wireless energy harvesting Unified Rectifier model Automated rectenna design Emerging rectenna techniques

On large-signal modeling of GaN HEMTs: past, development and future

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Chip 2023年第3期2卷 20-31页

作者： Haorui Luo Wenrui Hu yongxin guo Department of Electrical and Computer Engineering National University of SingaporeSingapore 117576Singapore National University of Singapore(Suzhou)Research Institute Suzhou 215123China

In the past few decades,circuits based on gallium nitride high elec-tron mobility transistor(GaN HEMT)have demonstrated exceptional potential in a wide range of high-power and high-frequency applica-tions,such as the new generation mobile communications,object de-tection and consumer electronics,etc.As a critical intermediary be-tween GaN HEMT devices and circuit-level applications,GaN HEMT large-signal models play a pivotal role in the design,application and development of GaN HEMT devices and circuits.This review pro-vides an in-depth examination of the advancements in GaN HEMT large-signal modeling in recent decades.Detailed and comprehensive coverage of various aspects of GaN HEMT large-signal model was of-fered,including large-signal measurement setups,classical formula-tion methods,model classification and non-ideal effects,etc.In order to better serve follow-up researches,this review also explored poten-tial future directions for the development of GaN HEMT large-signal modeling.

关键词： Gallium nitride High electron mobility transistors Large-signal model

An adaptive LIC based geographic flow field visualization method by means of rotation distance

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International Journal of Digital Earth 2023年第1期16卷 891-909页

作者： Yulin Ding Daiyu Shang Tingchen Wu Qing Zhu Liguo Zhang yongxin guo Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduPeople's Republic of China

Geographic visualization is essential for explaining and describing spatiotemporal geographical processes in flow fields.However,due to multi-scale structures and irregular spatial distribution of vortices in complex geographic flow fields,existing two-dimensional visualization methods are susceptible to the effects of data accuracy and sampling resolution,resulting in incomplete and inaccurate vortex information.To address this,we propose an adaptive Line Integral Convolution(LIC)based geographic flow field visualization method by means of rotation distance.Our novel framework of rotation distance and its quantification allows for the effective identification and extraction of vortex features in flow fields effectively.We then improve the LIC algorithm using rotation distance by constructing high-frequency noise from it as input to the convolution,with the integration step size adjusted.This approach allows us to effectively distinguish between vortex and non-vortex fields and adaptively represent the details of vortex features in complex geographic flow fields.Our experimental results show that the proposed method leads to more accurate and effective visualization of the geographic flow fields.

关键词： Geographic flow field vortex feature rotation distance adaptive line integral convolution two-dimensional visualization

Dopaminergic Neurons in the Ventral Tegmental–Prelimbic Pathway Promote the Emergence of Rats from Sevoflurane Anesthesia

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Neuroscience Bulletin 2022年第4期38卷 417-428页

作者： Yanping Song Ruitong Chu Fuyang Cao Yanfeng Wang Yanhong Liu Jiangbei Cao yongxin guo Weidong Mi Li Tong Anesthesia and Operation Center The First Medical Center of ChinesePLA General HospitalBeijing 100853China Department of Anesthesia Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China Chinese PLA Medical School Beijing 100853China Department of Anesthesia The Sixth Medical Center of ChinesePLA General HospitalBeijing 100048China Department of Anesthesia Xiangya HospitalCentral South UniversityChangsha 410008China

Dopaminergic neurons in the ventral tegmental area(VTA)play an important role in cognition,emergence from anesthesia,reward,and aversion,and their projection to the cortex is a crucial part of the"bottom-up"ascending activating system.The prelimbic cortex(PrL)is one of the important projection regions of the VTA.However,the roles of dopaminergic neurons in the VTA and the VTADA–PrL pathway under sevoflurane anesthesia in rats remain unclear.In this study,we found that intraperitoneal injection and local microinjection of a dopamine D1 receptor agonist(Chloro-APB)into the PrL had an emergence-promoting effect on sevoflurane anesthesia in rats,while injection of a dopamine D1 receptor antagonist(SCH23390)deepened anesthesia.The results of chemogenetics combined with microinjection and optogenetics showed that activating the VTADA–PrL pathway prolonged the induction time and shortened the emergence time of anesthesia.These results demonstrate that the dopaminergic system in the VTA has an emergence-promoting effect and that the bottom-up VTADA–PrL pathway facilitates emergence from sevoflurane anesthesia.

关键词： Ventral tegmental area Prelimbic cortex Dopamine Sevoflurane General anesthesia

Integrated representation of geospatial data,model,and knowledge for digital twin railway

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International Journal of Digital Earth 2022年第1期15卷 1657-1675页

作者： Hankan Li Qing Zhu Liguo Zhang Yulin Ding yongxin guo Haoyu Wu Qiang Wang Runfang Zhou Mingwei Liu Yan Zhou Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduChina Faculty of Geomatics Lanzhou Jiaotong UniversityLanzhouPeople’s Republic of China School of Resources and Environment University of Electric Science and Technology of ChinaChengduPeople’s Republic of China The Key Laboratory of Urban Land Resources Monitoring and Simulation Ministry of Natural ResourcesShenzhenPeople’s Republic of China

The real-time accurate description of all spatial features of railway and their spatiotemporal relationships is a crucial factor in realizing comprehensive management and related decision-making within the entire life cycle of railways.Nevertheless,available spatiotemporal data models mainly use static historical sequence data,which are insufficient to support multi-source heterogeneous real-time sensed data;they lack a systematic depiction of the interactive relationships among multiple feature entities,and are limited to low-level descriptive analysis.Therefore,this study proposes a data-model-knowledge integrated representation data model for a digital twin railway,which explicitly describes the spatiotemporal,and interaction relationships among railway features through a conceptual knowledge graph.This study first analyzes the characteristics of railway features from above ground to underground,and then constructs a conceptual model to clearly describe the complex relationships among railway features.Secondly,a logical model is developed to illustrate the basic data structure.Thirdly,an ontology model is constructed as a basic framework for further deepening the domain knowledge graph.Finally,considering the prevention of landslides as an example,it demonstrates the abundant spatiotemporal relationships among railway related features.The results of this study bring more clear understanding of the complex interactive relationships of railway entities.

关键词： Digital twin railway data-model-knowledge spatiotemporal relationships

支气管插管与支气管封堵器对婴幼儿胸腔镜手术后转归影响的对比分析

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中华医学杂志 2024年第23期104卷 2154-2159页

作者：李泳鑫魏国陈刚李帆潘守东首都儿科研究所附属儿童医院麻醉科北京

目的比较支气管插管和支气管封堵器对婴幼儿胸腔镜手术后转归的影响。方法回顾性纳入2019年1月至2023年8月首都儿科研究所附属儿童医院择期行全身麻醉下单肺通气胸腔镜手术患儿387例, 其中男210例, 女177例, 年龄(17.5±8.3)个月。根据... 详细信息

目的比较支气管插管和支气管封堵器对婴幼儿胸腔镜手术后转归的影响。方法回顾性纳入2019年1月至2023年8月首都儿科研究所附属儿童医院择期行全身麻醉下单肺通气胸腔镜手术患儿387例, 其中男210例, 女177例, 年龄(17.5±8.3)个月。根据患儿术中单肺通气方式分为支气管插管组和支气管封堵器组, 并采用倾向性评分匹配最邻近匹配法匹配年龄因素, 最终支气管插管组纳入258例, 支气管封堵器组纳入129例。主要观察指标为两组患儿术后肺部并发症发生率。次要观察指标包括两组患儿术中低氧血症发生率、术毕氧合指数、术后拔除气管导管时间、术后住院时间和医疗费用等转归指标。结果支气管插管组和支气管封堵器组术后肺部并发症发生率分别为15.5%(40/258)和12.4%(16/129), 术中低氧血症发生率分别为20.2%(52/258)和16.3%(21/129), 术毕氧合指数[M(Q1, Q3)]分别为306(269, 323)和311(274, 336)mmHg(1 mmHg=0.133 kPa), 术后拔除气管导管时间分别为(9.2±4.5)和(8.9±4.2)min, 术后住院时间分别为(5.5±0.6)和(5.5±0.5)d, 医疗费用分别为(3.4±0.6)和(3.5±0.6)万元, 差异均无统计学意义(均P>0.05)。结论支气管插管和封堵器两种方式均可用于婴幼儿胸腔镜手术单肺通气, 不影响患儿术后转归。

关键词：儿童胸腔镜术后肺部并发症倾向性评分匹配