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Animal Nutrition 2021年第4期7卷 959-966页

作者： yongsen zhao Danping Wang Yanping Huang Dangdang Wu Xiaoming Ji Xiaobing Zhou Dong Xia Xiaojing Yang Key Laboratory of Animal Physiology&Biochemistry Nanjing Agricultural UniversityNanjing210095China Jiangsu Meilin Animal Husbandry Co.Ltd. China Institute of Animal Husbandry&Veterinary Sciences Shanghai Academy of Agricultural SciencesShanghai201106China

Maternal sodium butyrate(SB)intake has important effects on offspring growth and *** study aimed to investigate the impacts of maternal SB supplementation during gestation and lactation on fatty acid composition and lipid metabolism in the offspring skeletal muscle of *** sows(Yorkshire,parity 2 to 3)were assigned to the control group(diets without SB,n=10)and SB group(diets with 0.1%SB,n=10).The results showed maternal SB supplementation throughout gestation and lactation increased(P<0.05)body weight of offspring piglets at *** concentrations of triglyceride in plasma and milk were enhanced(P<0.05).Maternal SB induced(P<0.05)lipid accumulation with increased expression of peroxisome proliferator activated receptorγ(PPARγ)by enrichment of the acetylation of H3 acetylation K27(H3 K27)in offspring skeletal ***,the concentrations of C18:2 n-6,C18:3 n-3,total polyunsaturated fatty acid(PUFA),n-6 PUFA and n-3 PUFA decreased(P<0.05)in skeletal muscle of weaning piglets derived from SB ***,these results showed that maternal SB supplementation could influence offspring growth performance,lipid metabolism and fatty acid composition of the skeletal muscle.

关键词： Maternal butyrate Intramuscular fat Fatty acid composition Pig

基于特勒根拟功率定理的直流输电线路故障测距

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中国电机工程学报 2023年第9期43卷 3381-3388页

作者：王波刘世明赵永森电网智能化调度与控制教育部重点实验室(山东大学) 山东省济南市250061

高压直流输电系统的网络结构和故障特性对线路故障测距方案准确度提出更高要求,对此,该文提出一种基于特勒根拟功率定理的直流输电线路故障测距方案。首先,在分析直流线路贝瑞隆模型的基础上,首次提出特勒根拟功率定理应用于直流线路故... 详细信息

高压直流输电系统的网络结构和故障特性对线路故障测距方案准确度提出更高要求,对此,该文提出一种基于特勒根拟功率定理的直流输电线路故障测距方案。首先,在分析直流线路贝瑞隆模型的基础上,首次提出特勒根拟功率定理应用于直流线路故障分析的方案,并给出拟功率解析表达式。其次利用贝瑞隆模型构建拟功率基准值,并根据故障点处基准值与计算值相等的原则实现故障测距。最后,通过大量仿真,验证理论推导的正确性以及拟功率能有效反应故障位置,并验证该方案不受过渡电阻及故障类型的影响。该研究实现了低采样频率下高精度测距的目标。

关键词：高压直流输电线路故障定位故障分析特勒根拟功率定理分布参数模型

基于5G及IEC61850的韧性配网故障信息智能传输技术研究

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电力系统保护与控制 2022年第21期50卷 108-117页

作者：孙阳盛涂崎赵中华黄震宇赵永森李坤国网上海市电力公司上海200122 东方电子股份有限公司山东烟台264000 山东大学山东济南250061

现有城市配电网,尤其是在负荷密集区域,具有大量的10 kV开关站。但是现有配电网系统缺乏对10 kV开关站设备的有效监管能力,严重阻碍城市韧性配电网的建设。为此,提出了基于5G及IEC61850的韧性配网故障信息智能传输技术方案。该方案通过... 详细信息

现有城市配电网,尤其是在负荷密集区域,具有大量的10 kV开关站。但是现有配电网系统缺乏对10 kV开关站设备的有效监管能力,严重阻碍城市韧性配电网的建设。为此,提出了基于5G及IEC61850的韧性配网故障信息智能传输技术方案。该方案通过基于态势感知的保护设备自动发现识别技术自动识别感知开关站内网络变化。通过基于IEC61850通信的二次设备自动配置接入技术自动发现并配置保护装置。通过基于IEC61850的面向对象的立体数据模型到扁平化数据模型的免配置转换技术快速准确地实现电网保护故障信息主站与子站之间的信息转换与共享。通过基于5G网络的高速实时业务传输技术实现信息的高速、实时、可靠传输。搭建系统测试环境对该技术方案进行测试并在试点站进行试运行。结果表明该技术方案能够按需及时获取设备实时运行状态和重要动作信息,实现了对10 kV开关站的有效监管。

关键词： 5G IEC61850 免配置态势感知动态初始化数据转换

基于光学电流互感器的有源配电网相差保护方案

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电力系统自动化 2022年第22期46卷 173-181页

作者：刘世明赵永森王波赵文琛游欢欢南天琦电网智能化调度与控制教育部重点实验室(山东大学) 山东省济南市250061 广东电网有限责任公司广州供电局广东省广州市510620

分布式电源的接入改变了配电网的网络结构和故障特性,导致传统的三段式电流保护难以适用。纵联差动保护可以有效解决有源配电网中保护失效问题,但是存在通信通道和数据同步的问题。光学电流互感器具备功耗低、电绝缘性好等特点,但是受... 详细信息

分布式电源的接入改变了配电网的网络结构和故障特性,导致传统的三段式电流保护难以适用。纵联差动保护可以有效解决有源配电网中保护失效问题,但是存在通信通道和数据同步的问题。光学电流互感器具备功耗低、电绝缘性好等特点,但是受限于温度等因素的影响,难以在配电网中广泛应用。文中提出一种基于光学电流互感器的有源配电网相差保护方案。该方案通过光学电流互感器将电流信号转化为光强信号,然后通过光纤将对端光强信号传递至本端,有效地解决了纵联保护的通信通道和数据同步问题。方案采用相位差动保护,避免了温度和光源变化对光学电流互感器的影响。最后,仿真和动模实验验证了所提方案的可行性。

关键词：分布式电源有源配电网光学电流互感器相差保护数据同步

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仿生超浸润界面传感技术在生物分析中的应用

分析试验室 2024年第2期43卷 168-178页

作者：孙梦雪赵泳森李延雷高中锋山东省高校界面反应与传感分析重点实验室济南大学化学化工学院济南250024

仿生超浸润界面材料是构建高灵敏度、高特异性生物传感器的一类新兴材料,广泛适用于环境监测、生物医药、食品分析等领域。本文介绍了4种典型的超浸润界面,包括超疏水界面、超亲水界面、超润滑界面以及图案化浸润性界面,总结了界面浸润... 详细信息

仿生超浸润界面材料是构建高灵敏度、高特异性生物传感器的一类新兴材料,广泛适用于环境监测、生物医药、食品分析等领域。本文介绍了4种典型的超浸润界面,包括超疏水界面、超亲水界面、超润滑界面以及图案化浸润性界面,总结了界面浸润性调控在电化学、荧光、可视化、表面增强拉曼和可穿戴检测器件等技术中的研究和最新进展,阐述了传感器构建机理和检测机制。最后,对仿生超浸润界面传感技术在生命分析应用中存在的问题和现存的挑战进行了总结和讨论。

关键词：浸润性生物传感技术仿生材料生物分析应用

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浅论双师型教师在方剂学教学中的作用

中国中医药现代远程教育 2016年第20期14卷 7-8页

作者：朱亮贾永森赵舒华北理工大学中医学院中医系唐山063000

中医方剂学课程理论与实践并重,课程性质更趋近于临床,但因课时限制等原因,教师在中医本科教学中更加着重于理论知识的灌输,往往忽视了实践能力的培养。笔者从方剂学教学的实践与创新出发,探讨双师型教师在本科教学中的必要性,及具体所... 详细信息

中医方剂学课程理论与实践并重,课程性质更趋近于临床,但因课时限制等原因,教师在中医本科教学中更加着重于理论知识的灌输,往往忽视了实践能力的培养。笔者从方剂学教学的实践与创新出发,探讨双师型教师在本科教学中的必要性,及具体所采用的教学方法。双师型教师在教学中可激发学生学习积极性,加深学生对方剂学的理解,在中医学本科教学阶段培养更多临床实用型人才。

关键词：方剂学双师型教学法

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光伏胶膜专用EVA的结构与加工性能

现代塑料加工应用 2023年第6期35卷 14-16,24页

作者：方义赵勇森于文涛王朝雨中国石油独山子石化公司研究院新疆克拉玛依833699 新疆天利高新石化股份有限公司新疆克拉玛依833699 新疆橡塑材料实验室新疆克拉玛依833699

利用傅里叶变换红外光谱仪、差示扫描量热仪、凝胶渗透色谱仪、旋转流变仪、高压毛细流变仪等分析手段,对2种光伏胶膜专用乙烯-醋酸乙烯共聚物(EVA)样品(样品1和样品2)进行了结构与加工性能研究。结果表明:与样品2相比,样品1的醋酸乙烯(... 详细信息

利用傅里叶变换红外光谱仪、差示扫描量热仪、凝胶渗透色谱仪、旋转流变仪、高压毛细流变仪等分析手段,对2种光伏胶膜专用乙烯-醋酸乙烯共聚物(EVA)样品(样品1和样品2)进行了结构与加工性能研究。结果表明:与样品2相比,样品1的醋酸乙烯(VA)含量、熔体流动速率更趋近于中心值,密度、拉伸强度、维卡软化温度、毛细流变剪切黏度高,短支链含量、小晶点数量多,相对分子质量及其分布相当,熔融温度、结晶度、长支链支化程度低。2种样品抗热氧稳定性好,在较宽的剪切速率范围内无熔体破裂,可以满足流延膜机高速挤出制膜。

关键词：乙烯-醋酸乙烯共聚物基础物性相对分子质量及其分布流变性能流延

NUSAP1 potentiates chemoresistance in glioblastoma through its SAP domain to stabilize ATR

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2019-2029页

作者： Yuzu zhao Jiang He yongsen Li Shengqing Lv Hongjuan Cui State Key Laboratory of Silkworm Genome Biology Southwest UniversityChongqingChina Cancer Center Medical Research InstituteSouthwest UniversityChongqingChina Department of Neurosurgery Xinqiao HospitalThird Military Medical UniversityChongqingChina

NUSAP1,which is a microtubule-associated protein involved in mitosis,plays essential roles in diverse biological processes,especially in cancer *** this study,NUSAP1 was found to be overexpressed in GBM tissues in a grade-dependent manner compared with normal brain ***1 was also highly expressed in GBM patients,dead patients,and GBM *** addition,NUSAP1 was found to participate in cell proliferation,apoptosis,and DNA damage in GBM *** telangiectasia and Rad3-related protein(ATR)are a primary sensor of DNA damage,and ATR is also a promising target in cancer ***,we found that NUSAP1 positively regulated the expression of ***,NUSAP1 suppressed the ubiquitin-dependent proteolysis of *** SAP(SAF-A/B,Acinus,and PIAS)domain is a common motif of many SUMO(small ubiquitin-like modifier)E3 ligases,and this domain is involved in substrate recognition and ligase *** study further demonstrated that the SAP domain of NUSAP1 promoted the sumoylation of ATR,and thereby antagonized the ubiquitination of *** results suggest that NUSAP1 stabilizes ATR by ***,NUSAP1 potentiated chemotherapeutic resistance to temozolomide(TMZ)and doxorubicin(DOX)through its SAP ***,this study indicates that NUSAP1 is a promising therapeutic target in GBM.

关键词： AP1 damage ATR

Design of flower transplanting mechanisms based on double planet carrier non-circular gear train with complete rotation kinematic pair

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International Journal of Agricultural and Biological Engineering 2022年第3期15卷 9-15页

作者： Xiong zhao Xingxiao Ma Hongwei Liao yongsen Xiong Yadan Xu Jianneng Chen Faculty of Mechanical Engineering and Automation Zhejiang Sci-Tech UniversityHangzhou 310018China Key Laboratory of Crop Harvesting Equipment Technology of Zhejiang Province Jinhua 321017ZhejiangChina Hangzhou Vocational&Technical College Hangzhou 310018China

In view of the problems of the existing mechanisms based on 2R open-chain planetary gear train for seedling transplanting,such as the bad tracking flexibility,low positioning accuracy,and high structure design difficulties of the mechanisms based on 3R open-chain planetary gear train for seedling *** this paper,a transplanting mechanism based on the solution domain synthesis of a 3R open-chain-based complete rotation kinematic pair,a gear train with a single cycle integral rotating pair,is *** Burmester curve equation is derived from the given transplanting trajectory and four exact poses corresponding to each other on the rotation ***,the open-chain road model of the 3R complete rotation kinematic pair is obtained under the constraint governed by the judgment condition of the hinge integral rotating ***,combined with our developed in-house optimization software,the solution to the optimal parameters for the transplanting mechanism can be optimized according to the target ***,the feasibility of the design method is verified by transplanting testing,where kale seedlings with ages of about 20 d and heights of about 80-120 mm are *** experimental results show that the actual motion trajectory of the prototype is basically identical to the theoretical trajectory,validating the feasibility of transplanting mechanism design,parts processing,and test-bed *** the statistical analysis,the average success rate of transplanting is 90.625%,and the reliability of designed mechanism is *** study provides a promising solution for the seedling transplanting of two-planet scaffold pots.

关键词： 3R open-chain planetary gear train complete rotation kinematic pair precise manipulation plug seedling

On the origin of SARS-CoV-2——The blind watchmaker argument

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Science China(Life Sciences) 2021年第9期64卷 1560-1563页

作者： Chung-I Wu Haijun Wen Jian Lu Xiao-dong Su Alice CHughes Weiwei Zhai Chen Chen Hua Chen Mingkun Li Shuhui Song zhaohui Qian Qihui Wang Bingjie Chen Zixiao Guo yongsen Ruan Xuemei Lu Fuwen Wei Li Jin Le Kang Yongbiao Xue Guoping zhao Ya-Ping Zhang State Key Laboratory of Biocontrol School of Life SciencesSun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Protein and Plant Gene Research Center for BioinformaticsSchool of Life SciencesPeking UniversityBeijing 100871China Landscape Ecology Group Center for Integrative ConservationXishuangbanna Tropical Botanical GardenChinese Academy of SciencesMengla 666303China Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China Biomedical Innovation Center Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Beijing Institute of Genomics Chinese Academy of Sciencesand China National Centre for BioinformationBeijing 100101China Institute of Pathogen Biology Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100176China CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China CAS Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China MOE Key Laboratory of Contemporary Anthropology Department of Anthropology and Human GeneticsSchool of Life SciencesFudan UniversityShanghai 200433China State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China Key Laboratory of Synthetic Biology Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200032China

In the comparison with SARS-CoVof 2003,SARS-CoV-2 is extremely well adapted to the human populations and its adaptive shift from the animal host to humans must have been even more *** the blind watchmaker argument,such an adaptive shift can only happen prior to the onset of the current pandemic and with the aid of step-by-step selection.

关键词： argument origin adapted

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