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liu Chenggan: A library Culture Preserver in Modern China

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China & The World Cultural Exchange 2009年第2期75卷 10-11页

作者： li yongming & hu hu

Huzhou, a historical city in the southeast province o Zhejiang, was dubbed as the "hometown of book collection" by Wang Guowei, a great scholar living in the late Qing Dynasty. The most famous private collection house in Huzhou is "Jia Ye Tang" built by a local millionaire named liu Chenggan (1881-1963) in the first half of the 20th century.

关键词：文化保存图书馆近代历史名城百万富翁王国维收藏家湖州

区块链背景下数字版权全链条保护的困境与出路

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科技管理研究 2022年第10期42卷 140-150页

作者：李永明赖利娜浙江大学光华法学院浙江杭州310008

面向新一代信息技术发展引发的数字版权登记确权成本高、效率低以及授权交易权属流转不清晰、监测维权取证难等困境,基于数字版权全链条中版权登记、授权许可、监测维权三大场景,应用区块链技术可以有效降低数字版权登记成本并提高效率... 详细信息

面向新一代信息技术发展引发的数字版权登记确权成本高、效率低以及授权交易权属流转不清晰、监测维权取证难等困境,基于数字版权全链条中版权登记、授权许可、监测维权三大场景,应用区块链技术可以有效降低数字版权登记成本并提高效率、保证许可授权的安全透明、实时监测侵权并取证、出证,但同时也面临着如版权登记效力不明确,作品独创性判断的缺失,限制合理使用、著作权修改权和法律适用以及监测维权的证据证明力等诸多挑战。为应对区块链应用于数字版权全链条保护中可能存在的法律问题,可构建区块链版权登记确权实质审查制,从法律上推动智能合约的发展与应用,并建立统一的区块链存证司法审查方式。

关键词：区块链数字版权版权登记授权许可监测维权

低氧对大鼠牙周组织成骨及成血管能力影响的初步研究

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实用口腔医学杂志 2023年第3期39卷 307-312页

作者：王洁朱锐李永明同济大学口腔医学院·附属口腔医院正畸二科上海牙组织修复与再生工程技术研究中心200072

目的:探讨低氧对大鼠牙周组织成骨、成血管能力的影响。方法:20只1周龄SPF级雄性Wistar大鼠随机分为单侧鼻阻塞组(unilateralnasalobstruction,UNO)和假手术组(SHAM),每组10只。同一饲养条件饲养8周后,采用RT-qPCR法、Westernblot、免... 详细信息

目的:探讨低氧对大鼠牙周组织成骨、成血管能力的影响。方法:20只1周龄SPF级雄性Wistar大鼠随机分为单侧鼻阻塞组(unilateralnasalobstruction,UNO)和假手术组(SHAM),每组10只。同一饲养条件饲养8周后,采用RT-qPCR法、Westernblot、免疫荧光染色、组织切片染色等方法,比较两组大鼠牙周组织中低氧诱导因子-1α(HIF-1α)、血管内皮生长因子(VEGF)、碱性磷酸酶(ALP)的表达差异。结果:低氧条件下,UNO大鼠牙周组织中HIF-1α、VEGF、ALP表达均显著升高(P<0.05)。结论:低氧激活大鼠牙周组织HIF-1α/VEGF信号通路,促进牙周膜中ALP的表达。

关键词：阻塞性睡眠呼吸暂停低通气综合征牙周炎低氧诱导因子-1α 成骨成血管

安徽省宁国市山核桃种植区典型滑坡机制与稳定性分析——以石岭村滑坡为例

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中国地质调查 2024年第1期11卷 93-104页

作者：邓佳良黄黄王耀李永明吴昊黄蒙安徽省地质调查院安徽合肥230001 安徽省地质矿产勘查局311地质队安徽安庆246000

宁国山核桃种植区环境地质条件复杂,人类活动活跃,降雨充沛,是安徽省滑坡灾害极高易发区之一。选择种植区东部石岭村滑坡为研究对象,采用遥感、地形测量、地质勘查等工作手段,对滑坡的变形特征、形成条件、破坏机制及稳定性等特征进行... 详细信息

宁国山核桃种植区环境地质条件复杂,人类活动活跃,降雨充沛,是安徽省滑坡灾害极高易发区之一。选择种植区东部石岭村滑坡为研究对象,采用遥感、地形测量、地质勘查等工作手段,对滑坡的变形特征、形成条件、破坏机制及稳定性等特征进行详细研究,并提出防治建议。研究结果表明:石岭村滑坡为一受基覆界面控制的小型复合式土质滑坡,在工况Ⅱ(自重+持续暴雨)下稳定系数为0.8543(不稳定),处于蠕变状态,复活的可能性较大;其主控因素为软弱的岩土体结构和适宜的地形地貌条件,诱发因素为强降雨和人类工程活动;建议对种植区自然斜坡进行工程治理,同时改变山核桃采摘方式(如采用低空挂网兜拾),恢复植被,减少水土流失。研究成果可为种植区滑坡灾害早期识别和防治等提供重要借鉴。

关键词：山核桃种植区石岭村滑坡形成条件破坏机制稳定性评价

区块链赋能:网络化开放创新范式下企业知识产权保护

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科技管理研究 2023年第23期43卷 213-221页

作者：赖利娜李永明杭州电子科技大学人文艺术与数字媒体学院法学院浙江杭州310018 浙江大学光华法学院浙江杭州310008

区块链的去中心化、可追溯、不可篡改等特性适用于知识产权领域,应对信息披露悖论,去中心化降低登记成本,智能合约提高授权效率,不可篡改性保障可回溯性。然而,区块链应用于知识产权保护引发认证标准不统一、许可的权利移转难以起到公... 详细信息

区块链的去中心化、可追溯、不可篡改等特性适用于知识产权领域,应对信息披露悖论,去中心化降低登记成本,智能合约提高授权效率,不可篡改性保障可回溯性。然而,区块链应用于知识产权保护引发认证标准不统一、许可的权利移转难以起到公示效果,且区块链特性与知识产权法律制度存在冲突。为此,建议在区块链支撑下出台知识产权标准与应用标准,并且运用区块链推进企业数字知识产权保护平台构建,利用区块链特征助力产业数字化转型。

关键词：区块链网络化开放创新范式知识产权

Reducible Discord in Generic Three-Qubit Pure W States

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ZTE Communications 2013年第3期11卷 33-35页

作者： Zhengjun Xi Zhihui li yongming li College of Computer Science Shaanxi Normal University College of Mathematics & Information Science Shaanxi Normal University

Quantum discord is the most prominent of quantum correlations, but it does not have unique generalizations to the multipartite case. W states are especially useful for secure communication. In this paper, we propose that the quantum correlation in generic three-qubit pure W states can be given by the two-qubit discords of these states.

关键词： quantum discord W state quantum correlation

Adenosine triphosphate mediates the pain tolerance effect of manual acupuncture at Zusanli(ST36) in mice

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Journal of Traditional Chinese Medicine 2024年第4期44卷 660-669页

作者： li Zhongzheng ZHAO Yadan Ma Weigang Zhang Yonglong XU Zhifang XI Qiang li Yanqi QIN Siru ZHANG Zichen WANG Songtao ZHAO Xue liU Yangyang GUO Yi GUO yongming Research Center of Experimental Acupuncture Science Tianjin University of Traditional Chinese Medicine National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Department of Acupuncture and Moxibustion Qingdao Hiser Hospital Affiliated of Qingdao University(Qingdao Traditional Chinese Medicine Hospital) School of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine School of Acupuncture and Moxibustion and Tuina Tianjin University of Traditional Chinese Medicine

OBJECTIVE: To investigate the mechanisms behind the effects of acupuncture in Traditional Chinese Medicine,we delved into the adenosine triphosphate/peripheral purinergic P2X receptor 3(ATP/P2X3) receptor signaling system as an indicator of the body's energy state,commonly referred to as "Qi".METHODS: The tail-flick test was utilized to explore the impact of acupuncture on pain tolerance threshold(PTT)in mice, while also assessing adenosine(ADO) levels and adenylate energy charge(EC) at Zusanli(ST36). The study further investigated the dose-dependent effects of acupuncture on PTT and ADO levels at Zusanli(ST36).To shed light on the underlying mechanisms of acupuncture's effects, the study examined the impact of ATP, a P2X3 receptor antagonist, and adenosine disodium on PTT following acupuncture administration. RESULTS: Acupuncture at Zusanli(ST36) led to significant improvements in PTT in mice, with the most effective interventions being twirling for 2 min and needle retention for 28 min. These interventions also resulted in significant increases in ATP levels. The effects of acupuncture were further augmented by administration of different doses of ATP at Zusanli(ST36), and pretreatment with a P2X3 receptor antagonist decreased PTT. Adenylate EC peaked at 30 min after intraperitoneal injection of ATP, and pretreatment with various doses of i.p. ATP 30 min prior to acupuncture increased PTT in a dose-dependent manner. Additionally, pretreatment with an i.p. or intramuscular injection of adenosine disodium enhanced the effects of acupuncture. CONCLUSION: This research provides compelling evidence that ATP is involved in the regulation of PTT through acupuncture, revealing new avenues for achieving enhanced clinical outcomes.

关键词： acupuncture adenosine triphosphate energy state point ST36 (Zusanli) receptors, purinergic P2X3

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Failure pressure calculation of fracturing well based on fluid-structure interaction

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Journal of Rock Mechanics and Geotechnical Engineering 2011年第S1期3卷 450-456页

作者： Jinzhou Zhao Lan Ren Min li yongming li State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500China

Failure pressure is a key parameter in reservoir hydrofracturing operation. Existing analytical methods for calculating the failure pressure are based on the assumption that borehole fluid is under two extreme conditions: non-infiltration or complete infiltration. The assumption is not suitable for the actual infiltration process, and this will cause a great error in practical calculation. It shows that during the injection process, the dynamic variation in effective stress-dependent permeability has an influence on the infiltration, and the influence also brings about calculation errors. Based on the fluid-structure interaction and finite element method (FEM), considering partial infiltration during injection process, a numerical model for calculating rock failure pressure is established. According to the analysis of permeability test results and response-surface method, a new variation rule of rock permeability with the change of effective stress is presented, and the relationships among the permeability, confining pressure and pore pressure are proposed. There are some differences between the dynamic value of permeability-effective-stress coefficient observed herein and the one obtained by the classical theory. Combining with the numerical model and the dynamic permeability, a coupling method for calculating failure pressure is developed. Comparison of field data and calculated values obtained by various methods shows that accurate values can be obtained by the coupling method. The coupling method can be widely applied to the calculation of failure pressure of reservoirs and complex wells to achieve effective fracturing operation.

关键词： failure pressure fluid-structure interaction hydrofracturing coupling method response-surface method

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一种强电磁设备低频辐射特性等效建模方法

电工技术学报 2023年第20期38卷 5354-5368页

作者：陈豪刘其凤李永明黄琛张淮清重庆大学输配电装备及系统安全与新技术国家重点实验室重庆400044 中国舰船研究设计中心电磁兼容性重点实验室武汉430064

随着高开关频率的新型电力电子器件广泛应用到舰船等平台上的强电磁设备中,强电磁设备产生的低频辐射会对平台上的敏感设备产生严重的影响,因此必须对强电磁设备的低频辐射特性进行准确建模表征,支撑开展强电磁设备低频场分布特征的量... 详细信息

随着高开关频率的新型电力电子器件广泛应用到舰船等平台上的强电磁设备中,强电磁设备产生的低频辐射会对平台上的敏感设备产生严重的影响,因此必须对强电磁设备的低频辐射特性进行准确建模表征,支撑开展强电磁设备低频场分布特征的量化预测,以便提升整个平台的电磁兼容性能。传统等效偶极子法在对大尺寸辐射源进行等效建模时,存在偶极子阵列所需的等效偶极子源数量多,高度、位置选择困难等问题。为解决上述问题,该文提出一种基于自适应差分进化算法的强电磁设备低频辐射特性等效偶极子建模的方法。该方法从强电磁设备附近的近场辐射特性测试数据出发,将强电磁设备低频辐射等效为分布在多个区域的偶极子阵列组合的分布式辐射源,并通过自适应差分进化算法优化各区域偶极子阵列的数量、位置以及高度等等效源参数,并通过试验和算例验证该方法可在满足一定精度条件下,能大幅度减小偶极子数量,得到强电磁设备最优的低频分布式等效源模型。

关键词：低频辐射干扰等效源法三维磁偶极子阵列自适应差分进化算法近场数据