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生物多糖冲洗胶液致严重过敏性休克1例并文献回顾

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中华麻醉学杂志 2024年第2期44卷 249-250页

作者：李想罗铁山刘文家杨永锦阳光融和医院麻醉手术科潍坊261072

患者,女性,年龄27岁,身高170 cm,体质量55 kg,门诊以"急性阑尾炎伴弥漫性腹膜炎"入院。既往体健,有过敏史(具体不详),5个月前有"宫外孕"全麻手术史。体格检查:体温36.5 ℃,脉搏76次/min,BP 114/74 mmHg(1 mmHg=0.133 kPa)。术前血常规:... 详细信息

患者,女性,年龄27岁,身高170 cm,体质量55 kg,门诊以"急性阑尾炎伴弥漫性腹膜炎"入院。既往体健,有过敏史(具体不详),5个月前有"宫外孕"全麻手术史。体格检查:体温36.5 ℃,脉搏76次/min,BP 114/74 mmHg(1 mmHg=0.133 kPa)。术前血常规:白细胞计数19.93×10^(9)/L、中性粒细胞百分比90.30%,血红蛋白浓度(Hb)124 g/L、血小板计数192×10^(9)/L,凝血功能、心电图等检查大致正常,ASA分级ⅡE级;拟在全身麻醉下行"腹腔镜下阑尾切除术"。

关键词：弥漫性腹膜炎急性阑尾炎血红蛋白浓度白细胞计数文献回顾全麻手术血小板计数体格检查

基于“慕课+虚拟仿真”的生理学实验评价体系改革

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科教文汇 2024年第1期 72-76页

作者：杨永进吴瑶张帆湖北工程学院生命科学技术学院湖北孝感432000

传统的生理学实验课考核在内容和形式上比较单一,无法对学生各方面的能力和素养进行全面评估。湖北工程学院将慕课和虚拟仿真实验深度融合,形成一体化实验在线学习平台。利用平台对学习过程中产生的学习数据进行采集、统计和分析,并将... 详细信息

传统的生理学实验课考核在内容和形式上比较单一,无法对学生各方面的能力和素养进行全面评估。湖北工程学院将慕课和虚拟仿真实验深度融合,形成一体化实验在线学习平台。利用平台对学习过程中产生的学习数据进行采集、统计和分析,并将此作为过程性评价的依据,构建了一个全新的生理学实验多元学习评价体系,并通过调查问卷和统计学方法评估其实施效果。研究结果表明,新的评价体系能够对学生进行全面、客观和准确的评价,同时很好地发挥了以评促学的作用,具有较强的应用和推广价值。

关键词：慕课虚拟仿真生理学实验评价体系改革

基于叙事理论的亲情护理对成人癫痫患者自我管理能力的影响

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癫痫与神经电生理学杂志 2024年第2期33卷 77-81页

作者：杨勇进王耀窦文凯徐强中国科学技术大学附属第一医院/安徽省立医院神经内科安徽合肥230001

目的探讨基于叙事理论的亲情护理服务干预对成人癫痫患者自我管理能力的影响。方法选取2020年8月至2022年8月中国科学技术大学附属第一医院神经内科收治的100例成人癫痫患者作为研究对象,随机分为对照组和观察组各50例。对照组予以常规... 详细信息

目的探讨基于叙事理论的亲情护理服务干预对成人癫痫患者自我管理能力的影响。方法选取2020年8月至2022年8月中国科学技术大学附属第一医院神经内科收治的100例成人癫痫患者作为研究对象,随机分为对照组和观察组各50例。对照组予以常规护理,观察组予以基于叙事理论的亲情护理。比较两组成人癫痫患者的自我管理能力、生活质量及心理状态等。结果经两种不同方式护理后,观察组患者的自我管理能力评分显著高于对照组,差异有统计学意义(P<0.05);观察组患者的生活质量得分明显高于对照组,差异有统计学意义(P<0.05);观察组患者的焦虑自评量表及抑郁自评量表评分明显低于对照组,差异有统计学意义(P<0.05)。结论基于叙事理论的亲情护理服务干预可以强化成人癫痫患者的自我管理能力,提升患者的睡眠质量及生活质量,并可缓解患者的不良情绪,改善其心理状态,缩短其康复进程。

关键词：叙事理论亲情干预成人癫痫患者自我管理能力生活质量心理状态

补骨脂素调控Keap1/Nrf2通路减轻丙泊酚诱导的幼龄大鼠神经毒性

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中国优生与遗传杂志 2024年第4期32卷 686-693页

作者：陈宇刘文家李志鹏杨永锦昌乐齐城中医院麻醉科山东潍坊262400 阳光融和医院麻醉科山东潍坊261000 昌乐县人民医院麻醉科山东潍坊262400

目的探讨补骨脂素对幼龄大鼠神经毒性的保护作用及机制。方法采用100μmol/L丙泊酚孵育海马细胞系HT22细胞6h诱导细胞炎性,设置对照组、丙泊酚组、丙泊酚+补骨脂素(1、5、10μmol/L)组、丙泊酚+补骨脂素(10μmol/L)+Keap1/Nrf2通路抑制... 详细信息

目的探讨补骨脂素对幼龄大鼠神经毒性的保护作用及机制。方法采用100μmol/L丙泊酚孵育海马细胞系HT22细胞6h诱导细胞炎性,设置对照组、丙泊酚组、丙泊酚+补骨脂素(1、5、10μmol/L)组、丙泊酚+补骨脂素(10μmol/L)+Keap1/Nrf2通路抑制剂(KI696,5μmol/L)组。CCK8试验检测细胞活力,流式细胞术检测凋亡。幼龄SD大鼠随机分为对照组(C组)、丙泊酚组(P组)、丙泊酚+补骨脂素组(PP组)、丙泊酚+补骨脂素+KI696组(PPI组)。P组大鼠腹腔注射丙泊酚50 mg/kg,PP组注射丙泊酚和补骨脂素20 mg/kg,PPI组注射丙泊酚、补骨脂素和KI69630μmol/kg。采用Nissl染色观察海马组织病理结构变化,ELISA法检测细胞和组织炎症反应(IL-6和TNF-α水平)和氧化应激(MDA含量、SOD和GSH活性),Westernblot检测Keap1和Nrf2蛋白表达。结果与对照组相比较,丙泊酚组HT22细胞活力明显降低,细胞凋亡、Keap1蛋白水平、炎症和氧化应激显著升高(P<0.05);补骨脂素以剂量依赖的形式改善细胞神经炎症和氧化应激(P<0.05),KI696处理可逆转补骨脂素对细胞功能的保护作用。与C组比较,P组大鼠海马组织炎症和氧化应激加重。补骨脂素处理减轻了大鼠海马组织神经元受损。结论补骨脂素治疗可激活Keap1/Nrf2通路缓解丙泊酚诱导的幼龄大鼠神经毒性。

关键词：补骨脂素丙泊酚 Keap1/Nrf2通路神经毒性

Improving path planning efficiency for underwater gravity-aided navigation based on a new depth sorting fast search algorithm

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Defence Technology（防务技术） 2024年第2期32卷 285-296页

作者： Xiaocong Zhou Wei Zheng Zhaowei Li Panlong Wu yongjin Sun School of Automation Nanjing University of Science and TechnologyNanjing210094China China Academy of Aerospace Science and Innovation Beijing100176China Qian Xuesen Laboratory of Space Technology China Academy of Space TechnologyBeijing100094China School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin150001China

This study focuses on the improvement of path planning efficiency for underwater gravity-aided ***,a Depth Sorting Fast Search(DSFS)algorithm was proposed to improve the planning speed of the Quick Rapidly-exploring Random Trees*(Q-RRT*)algorithm.A cost inequality relationship between an ancestor and its descendants was derived,and the ancestors were filtered ***,the underwater gravity-aided navigation path planning system was designed based on the DSFS algorithm,taking into account the fitness,safety,and asymptotic optimality of the routes,according to the gravity suitability distribution of the navigation ***,experimental comparisons of the computing performance of the ChooseParent procedure,the Rewire procedure,and the combination of the two procedures for Q-RRT*and DSFS were conducted under the same planning environment and parameter conditions,*** results showed that the computational efficiency of the DSFS algorithm was improved by about 1.2 times compared with the Q-RRT*algorithm while ensuring correct computational results.

关键词： Depth Sorting Fast Search algorithm Underwater gravity-aided navigation Path planning efficiency Quick Rapidly-exploring Random Trees*(QRRT*)

A Novel Framework to Construct S-Box Quantum Circuits Using System Modeling: Application to 4-Bit S-Boxes

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 545-561页

作者： yongjin Jeon Seungjun Baek Jongsung Kim Department of Financial Information Security Kookmin UniversitySeoul02707Republic of Korea

Quantum computers accelerate many algorithms based on the superposition principle of quantum *** Grover algorithm provides significant performance to malicious users attacking symmetric key *** the performance of attacks using quantum computers depends on the efficiency of the quantum circuit of the encryption algorithms,research research on the implementation of quantum circuits is *** paper presents a new framework to construct quantum circuits of substitution boxes(S-boxes)using system *** model the quantum circuits of S-boxes using two layers:Toffoli and linear *** generate vector spaces based on the values of qubits used in the linear layers and apply them to find quantum *** framework finds the circuit bymatching elements of vector spaces generated fromthe input and output of a given S-box,using the forward search or themeet-in-the-middle *** developed a tool to apply this framework to 4-bit *** the 4-bit S-box quantum circuit construction tool LIGHTER-R only finds circuits that can be implemented with four qubits,the proposed tool achieves the circuits with five *** proposed tool can find quantum circuits of 4-bit odd permutations based on the controlled NOT,NOT,and Toffoli gates,whereas LIGHTER-R is unable to perform this task in the same *** expect this technique to become a critical step toward optimizing S-box quantum circuits.

关键词： System modeling quantum circuit S-box circuit quantum computer

Bifunctional interstitial phosphorous doping strategy boosts platinum-zinc alloy for efficient ammonia oxidation reaction and hydrogen evolution reaction

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Nano Research 2024年第3期17卷 1182-1189页

作者： Tianqi Yu Kexin Tan Jia Wu yongjin Zou Shibin Yin Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Information Materials Guilin University of Electronic TechnologyGuilin 541004China

It is still a lack of bifunctional catalysts for ammonia oxidation reaction(AOR)and hydrogen evolution reaction(HER)due to their different reaction *** this work,P is doped into PtZn alloy by calcination with NaH_(2)PO_(2) as P source to induce the lattice tensile strain of Pt and the electronic interaction between P and Zn,which optimizes the AOR and HER activity *** sample with the optimal P content can drive the AOR peak current density of 293.6 mA·mgPt^(-1),which is almost 2.7 times of *** HER,the overpotential at^(-1)0 mA·cm^(-2) is only 23 mV with Tafel slope of 34.1 mV·dec^(-1).Furthermore,only 0.59 V is needed to obtain 50 mA·mgPt^(-1) for ammonia electrolysis under a two-electrode ***,this work shows an ingenious method to design bifunctional catalysts for ammonia electrolysis.

关键词： PtZn alloy phosphorous doping ammonia oxidation reaction hydrogen evolution reaction bifunctional catalyst

Reactive molecular dynamics insight into the thermal decomposition mechanism of 2,6-Bis(picrylamino)-3,5-dinitropyridine

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Defence Technology（防务技术） 2024年第3期33卷 134-146页

作者： Jianbo Fu Hui Ren Xinzhou Wu yongjin Chen Mi Zhang Yazhi Cheng State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

2,6-bis(picrylamino)-3,5-dinitropyridine(PYX)has excellent thermostability,which makes its thermal decomposition mechanism receive much *** this paper,the mechanism of PYX thermal decomposition was investigated thoroughly by the ReaxFF-lg force field combined with DFT-B3LYP(6-311++G)*** detailed decomposition mechanism,small-molecule product evolution,and cluster evolution of PYX were mainly *** the initial stage of decomposition,the intramolecular hydrogen transfer reaction and the formation of dimerized clusters are earlier than the denitration *** the progress of the reaction,one side of the bitter amino group is removed from the pyridine ring,and then the pyridine ring is *** final products produced in the thermal decomposition process are CO_(2),H_(2)O,N_(2),and H_(2).Among them,H_(2)O has the earliest generation time,and the reaction rate constant(k_(3))is the *** clusters are formed during the decomposition of PYX,and the formation,aggregation,and decomposition of these clusters are strongly affected by *** low temperatures(2500 K-2750 K),many clusters are *** high temperatures(2750 K-3250 K),the clusters aggregate to form larger *** 3500 K,the large clusters decompose and become *** the late stage of the reaction,H and N in the clusters escaped almost entirely,but more O was trapped in the clusters,which affected the auto-oxidation process of ***'s initial decomposition activation energy(E_(a))was calculated to be 126.58 kJ/*** work contributes to a theoretical understanding of PYX's entire thermal decomposition process.

关键词： PYX Thermal decomposition ReaxFF-lg MD simulations Excellent thermostable explosives

国际经济新格局下中国企业进口再布局——基于量化进口贸易模型的结构式估计

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南开经济研究 2023年第4期 3-22页

作者：王永进杨璐南开大学经济学院 300071

本文基于中国多种所有制并存的制度背景,拓展了Antràs等(2017)提出的异质性企业全球采购框架,并使用中国工业企业与海关数据库,对中国企业全球采购布局的影响因素和特征事实进行估算,进而模拟了中美贸易摩擦以及RCEP政策导致采购市场... 详细信息

本文基于中国多种所有制并存的制度背景,拓展了Antràs等(2017)提出的异质性企业全球采购框架,并使用中国工业企业与海关数据库,对中国企业全球采购布局的影响因素和特征事实进行估算,进而模拟了中美贸易摩擦以及RCEP政策导致采购市场环境变化对中国企业进口布局调整的影响。结论表明:中国企业在不同国家的进口决策彼此关联,单个市场冲击会影响企业的全球采购布局;与民营企业相比,国有企业在企业数目和进口规模上均处于进口市场的“优势地位”,是我国扩大进口的重要依托;国有企业的进口固定成本更低,市场需求扩张更快速,二者共同驱动了其进口快速增长;国有企业采购策略集合之间的替代性强于民营企业的此替代性,即当美国采购潜力下降时国有企业更多地将进口需求转移到其他市场,当RCEP成员国的采购潜力上升时民营进口企业不仅对RCEP国家采购增加,而且对本国和第三国的采购也增加(与国有进口企业相反);RCEP协定的积极效果将弱化美国对华出口限制的负面影响,成为中国反击贸易保护主义、增强抵御国际风险能力的有效举措。

关键词：进口异质性企业结构式估计 RCEP 中美贸易