检索结果-南通市图书馆

维普期刊数据库博看期刊

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

艾滋病治愈研究的伦理探析

中国艾滋病性病 2024年第5期30卷 531-536页

作者：邹琳白晶翟晓梅马永慧厦门大学医学院生命伦理研究中心福建厦门361101 中国疾病预防控制中心营养与健康所北京100050 北京协和医学院群医学及公共卫生学院北京100732

cART是目前国际上治疗艾滋病最有效的方法,但其仅能抑制病毒复制而无法清除病毒。“柏林患者”治愈成功后,艾滋病治愈成为艾滋病研究热点和治疗新目标。然而艾滋病治愈研究大多仍处于研究初步阶段,给人们带来了更多疾病治愈希望的同时,... 详细信息

cART是目前国际上治疗艾滋病最有效的方法,但其仅能抑制病毒复制而无法清除病毒。“柏林患者”治愈成功后,艾滋病治愈成为艾滋病研究热点和治疗新目标。然而艾滋病治愈研究大多仍处于研究初步阶段,给人们带来了更多疾病治愈希望的同时,也出现了诸多的伦理问题,特别是cART中断(又称试验性停药,ATI)带来受试者风险和知情同意有效性的问题。本文通过分析艾滋病治愈研究中的技术和社会风险、受试者招募和知情同意、研究非直接参与者的风险以及治愈研究中的战争话语隐喻等几个焦点问题,进而提出艾滋病治愈研究的伦理治理建议,以期在伦理的规范和引导下,促进艾滋病治愈研究的健康发展。

关键词：艾滋病艾滋病治愈研究抗反转录病毒治疗中断伦理风险

在线全文

学校读者我要写书评

暂无评论

襄阳市现代设施渔业发展现状及对策浅析

南方农业 2024年第5期18卷 171-174页

作者：高可丽杜炎炎马永荟张杰襄阳市水产技术推广站湖北襄阳441000 枣阳市水产技术推广站湖北枣阳441200

现代设施渔业养殖是一种集约化高密度养殖,具有高产、高效、环保、省力等优点。发展设施渔业是促进渔业转型升级、实现科技兴渔、水产业绿色健康可持续发展的必由之路。为实现襄阳水产高质量发展,分析了襄阳市现代渔业设施养殖的基本情... 详细信息

现代设施渔业养殖是一种集约化高密度养殖,具有高产、高效、环保、省力等优点。发展设施渔业是促进渔业转型升级、实现科技兴渔、水产业绿色健康可持续发展的必由之路。为实现襄阳水产高质量发展,分析了襄阳市现代渔业设施养殖的基本情况,针对部分设施渔业选址不合理、渔业装置闲置荒废、新品苗种供应难、部分养殖环境污染大等问题,提出“因地制宜发展设施渔业、制定优惠政策解决融资难的现状、大力发展科技兴渔技术、建立设施渔业示范点、加强科技人才队伍建设、强化市场建设、提升产业化发展”等对策。

关键词：现代设施渔业科技兴渔高质量发展湖北省襄阳市

甘肃省及周边地区畜禽屠宰及市售环节沙门菌的分离鉴定及生物学特性分析

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中国畜牧兽医 2024年第8期51卷 3566-3576页

作者：马永辉曹青范子秋赵学慧芝吉马金锐何曾文张浩浩邓静崇倩张坤中宋维丽苟惠天薛惠文甘肃农业大学动物医学院兰州730070 临洮县龙门镇畜牧兽医站临洮730500

[目的]为合理防控沙门菌感染,本试验针对甘肃省及周边地区畜禽屠宰及市售环节沙门菌的感染情况开展研究。[方法]通过细菌分离培养、生化试验及分子生物学方法进行细菌分离鉴定,采用玻片凝集法和多位点序列分型(MLST)确定沙门菌血清型。... 详细信息

[目的]为合理防控沙门菌感染,本试验针对甘肃省及周边地区畜禽屠宰及市售环节沙门菌的感染情况开展研究。[方法]通过细菌分离培养、生化试验及分子生物学方法进行细菌分离鉴定,采用玻片凝集法和多位点序列分型(MLST)确定沙门菌血清型。采用结晶紫染色定量法评价分离株生物被膜形成能力,通过药敏试验检测分离菌对常用抗菌药的敏感性,评估4种市售消毒剂对沙门菌的灭菌效果,并确定其最小抑菌浓度(MIC)。[结果]细菌分离培养结果显示,疑似沙门菌分离株在BS平板上菌落呈黑色有金属光泽、棕褐色或灰色;在XLD平板上菌落有光泽且中心呈黑色,或呈现全部黑色的菌落;镜检显示为革兰阴性短杆菌。生化鉴定结果显示,分离菌硫化氢、葡萄糖、鸟氨酸、赖氨酸脱羧酶反应结果呈阳性;尿素酶、氰化钾、乳糖、蛋白胨水反应结果呈阴性。PCR扩增沙门菌特异性基因invA获得大小约为284 bp的目的条带,共分离到95株沙门菌,均属于肠道沙门菌的3种血清型——鼠伤寒沙门菌、德尔卑沙门菌、里森沙门菌。多位点序列分型共鉴定出3种,分别为ST34、ST469、ST40型。所有分离株均可形成生物被膜。药敏试验结果显示,所有菌株对米诺环素、万古霉素完全耐药,对阿米卡星、头孢曲松、卡那霉素、头孢唑啉、头孢氨苄、庆大霉素等敏感性较强,75.78%的菌株具有多重耐药性。4种消毒剂对分离株MIC存在差异,0.2%甲醛溶液的MIC为0.125~0.25 mg/mL,0.2%苯扎溴铵的MIC为0.0625~0.125 mg/mL,0.5%碘溶液的MIC为0.3125~0.625 mg/mL,2%氢氧化钠的MIC为1.25~2.5 mg/mL。[结论]德尔卑沙门菌、鼠伤寒沙门菌和里森沙门菌是当前屠宰场中沙门菌的主要血清型,具有生物被膜形成能力和多重耐药性,给公共卫生带来很大威胁。本研究为加强甘肃省及周边地区屠宰场及市售环节卫生管理提供科学依据。

关键词：沙门菌屠宰场血清型生物被膜多位点序列分型(MLST)

Night warming increases wheat yield by improving pre-anthesis plant growth and post-anthesis grain starch biosynthesis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第2期23卷 536-550页

作者： yonghui Fan Boya Qin Jinhao Yang Liangliang ma Guoji Cui Wei He Yu Tang Wenjing Zhang Shangyu ma Chuanxi ma Zhenglai Huang College of Agronomy Anhui Agricultural University/Key Laboratory of Wheat Biology and Genetic Improvement in South Yellow&Huai River ValleyMinistry of Agriculture and Rural AffairsHefei 230036China Xianyang Central Station for Agricultural Technology Extension Xianyang 712000China

Global climate change is characterized by asymmetric warming,i.e.,greater temperature increases in winter,spring,and nighttime than in summer,autumn,and *** experiments were conducted using four wheat cultivars,namely‘Yangmai 18’(YM18),‘Sumai 188’(SM188),‘Yannong 19’(YN19),and‘Annong 0711’(AN0711),in the two growing seasons of 2019-2020 and 2020-2021,with passive night warming during different periods in the early growth *** treatments were night warming during the tillering-jointing(NW_(T-J)),jointing-booting(NWJ-B),and booting-anthesis(NWB-A)stages,with ambient temperature(NN)as the *** effects of night warming during different stages on wheat yield formation were investigated by determining the characteristics of dry matter accumulation and translocation,as well as sucrose and starch accumulation in wheat *** wheat yields of all four cultivars were significantly higher in NW_(T-J)than in NN in the 2-year *** yield increases of semi-winter cultivars YN19 and AN0711 were greater than those of spring cultivars YM18 and *** NW_(T-J)increased wheat yield mainly by increasing the 1,000-grain weight and the number of fertile spikelets,and it increased dry matter accumulation in various organs of wheat at the anthesis and maturity stages by increasing the growth rate at the vegetative growth *** flag leaf and spike showed the largest increases in dry matter ***_(T-J)also increased the grain sucrose and starch contents in the early and middle grain-filling stages,promoting yield ***,night warming between the tillering and jointing stages increased the pre-anthesis growth rate,and thus,wheat dry matter production,which contributed to an increase in wheat yield.

关键词： wheat asymmetric warming dry matter accumulation and translocation starch yield

The accelerating nanoscale Kirkendall effect in Co films–native oxide Si(100)system induced by high magnetic fields

在线全文

学校读者我要写书评

暂无评论

Journal of materials Science & Technology 2020年第11期42卷 127-135页

作者： Yue Zhao Kai Wang Shuang Yuan yonghui ma Guojian Li Qiang Wang Institute of Microscale Optoelectronics Shenzhen UniversityShenzhen 578060China Key Laboratory of Electromagnetic Processing of materials(Ministry of Education) Northeastern UniversityShenyang 110819China Department of New Energy Science and Engineering School of MetallurgyNortheastern UniversityShenyang 110819China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China

The morphology evolution and magnetic properties of Co films–native oxide Si(100)were investigated at 873,973,and 1073 K in a high magnetic field of 11.5 *** of Kirkendall voids in the Co films was found to cause morphology evolution due to the difference in diffusion flux of Co and Si atoms through the native oxide *** high magnetic fields had considerable effect on the morphology evolution by accelerating nanoscale Kirkendall *** diffusion mechanism in the presence of high magnetic fields was given to explain the increase of diffusion *** morphology evolution of Co films on native oxide Si(100)under high magnetic fields during annealing resulted in the magnetic properties variation.

关键词： Thin films Annealing Diffusion Kirkendall effect High magnetic field

Help, hope and hype： ethical considerations of human microbiome research and applications

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2018年第5期9卷 404-415页

作者： yonghui ma Hua Chen Canhui Lan Jianlin Ren Centre for Bioethics Medical College Xiamen University Xiamen 361102 China Center for Bioethics School of Marxism Southern Medical University Guangzhou 510515 China Beijing Rexinchang Biotechnology Research Institute Co. Ltd Beijing China Institute for Human Microbiome Research Medical College Xiamen University Xiamen 361005 China Department of Digestive Diseases Zhongshan Hospital affiliated to Xiamen University Xiamen 361004 China

Recent years have witnessed an unprecedented explosion of scientific knowledge and advances in human microbiome research due to the emerging high-throughput molecular technologies. The term human microbiome refers to the population of microorganisms, including bacteria, viruses, fungi and protozoan, and their genetic material that live on and inside the human organisms （skin, mucous membranes, intestinal tract, etc.）（Honey, 2008）. A search of the literature at PubMed for the term ＂microbiome＂ in the title and abstract illustrates the fast progression of microbiome science. From 2006 to 2010 there were just 304 papers that used the word microbiome in their title and/or abstract, whereas the number has increased to 11,128 from 2011 to 2017.

关键词： Human Microbiome Research Fecal Microbiota Transplantation (FMT) Informed Consent Stool Bank Ethical, Legal, And Social Implications (ELSI)

Crystal structure determination of nanolaminated Ti_(5)Al_(2)C_(3) by combined techniques of XRPD,TEM and ab initio calculations

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2012年第4期1卷 268-273页

作者： Hui ZHANG Xiaohui WANG yonghui ma Luchao SUN Liya ZHENG Yanchun ZHOU Shenyang National Laboratory for materials Science Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China Graduate School of Chinese Academy of Sciences Beijing 100039China Science and Technology on Advanced Functional Composite Laboratory Aerospace Research Institute of Materials&Processing TechnologyNo.1 South Dahongmen RoadBeijing 100076China

Crystal structure of Ti_(5)Al_(2)C_(3)was determined by means of X-ray powder diffraction(XRPD),transmission electron microscopy(TEM)and ab initio *** contrast to the already known P63/mmc space group that the maX phases crystallize,it was demonstrated that the R3_m space group could better satisfy the experimental *** lattice parameters are a=0.30564 nm,c=4.81846 nm in a hexagonal unit cell.

关键词： Ti_(5)Al_(2)C_(3) crystal structure layered carbides transmission electron microscopy(TEM)

Effects of different magnetic flux densities on microstructure and magnetic properties of molecular-beam-vapor-deposited nanocrystalline Fee4Ni36 thin films

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of materials Science 2015年第2期9卷 163-169页

作者： Yongze CAO Qiang WANG Guojian LI yonghui ma Jiaojiao DU Jicheng HE Key Laboratory of Electromagnetic Processing of materials (Ministry of Education) Northeastern University Shenyang 110819 China

The nanocrystalline Fe64Ni36 thin films were prepared by molecular-beam- vapor deposition under different magnetic flux densities. The microstructure and magnetic properties of thin films were examined by AFM, TEM, HRTEM and VSM. The results show that with the increase of magnetic flux densities, the changing trend of the average particle size is the same as the coercive force except 6 T. Under 6 T condition, the thin film became the mixture of bcc and fcc phases, which leads to slight increase of the coercive force. In addition, the HRTEM result shows the short-range ordered clusters （embryos） or nucleation rate of thin films increase with increasing magnetic flux densities.

关键词： magnetic field intensity microstructure soft magnetic property coerciveforce crystallinity

High-performance and broadband photodetection of bicrystalline(GaN)_(1-x)(ZnO)_(x)solid solution nanowires via crystal defect engineering

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of materials Science & Technology 2021年第26期85卷 255-262页

作者： Zongyi ma Gang Li Xinglai Zhang Jing Li Cai Zhang yonghui ma Jian Zhang Bing Leng Natalia Usoltseva Vladimir An Baodan Liu School of materials Science and Engineering Liaoning Technical UniversityFuxin 123000China Shenyang National Laboratory for materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Structure Analysis Division Testing CenterInstitute of Metal ResearchChinese Academy of ScienceShenyang 110016China Department of Plastic Surgery The First Affiliated Hospital of China Medical UniversityShenyang 110001China School of Advanced manufacturing Technologies National Research Tomsk Polytechnic University30 Lenin Ave.Tomsk 634050Russia

Crystal defect engineering is widely used as an effective approach to regulate the optical and optoelectronic properties of semiconductor ***,photogenerated electron-hole pair recombination centers caused by structural defects usually lead to the reduction of optoelectronic *** this work,a high-performance photodetector based on(GaN)_(1-x)(ZnO)_(x)solid solution nanowire with bicrystal structure is fabricated and it shows excellent photoresponse to ultraviolet and visible *** highest responsivity of the photodetector is as high as 60,86 and 43 A/W under the irradiation of365 nm,532 nm and 650 nm,*** corresponding response time is as fast as 170,320 and 160 *** wide spectral responses can be attributed to various intermediate energy levels induced by the introduction of various structural defects and dopants in the solid solution ***,the peculiar bicrystal boundary along the axial direction of the nanowire provides two parallel and fast transmission channels for photo-generated carriers,reducing the recombination of photo-generated *** findings provide a valued example using crystal defect engineering to broaden the photoresponse range and improve the photodetector performance and thus can be extended to other material systems for various optoelectronic applications.

关键词： (GaN)1-x(ZnO)x Nanowires Photodetectors Broadband photodetection Crystal defect engineering