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Effects of fluid therapy combined with a preoperative glucose load regimen on postoperative recovery in patients with rectal cancer

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2662-2670页

作者： Lv-chi Xia Ke Zhang Chuan-wen wang Department of Emergency Medicine Jiujiang First People's HospitalJiujiang 332000Jiangxi ProvinceChina

BACKGROUND Patients with rectal cancer undergoing radical resection often have poor post-operative recovery due to preoperative fasting and water deprivation and the removal of diseased tissue,and have a high risk of ***,it is of great significance to apply appropriate rehydration regimens to patients un-dergoing radical resection of rectal cancer during the perioperative period to improve the postoperative outcomes of *** To analyze the effects of goal-directed fluid therapy(GDFT)with a preoperative glucose load regimen on postoperative recovery and complications in patients undergoing radical resection for rectal *** Patients with rectal cancer who underwent radical resection(n=184)between January 2021 and December 2023 at our hospital were randomly divided into either a control group or an observation group(n=92 in each group).Both groups received a preoperative glucose load regimen,and routine fluid replacement and GDFT were additionally implements in the control and observation groups,*** operative conditions,blood levels of lactic acid and inflammatory markers,postoperative recovery,cognitive status,hemodynamic indicators,brain oxygen metabolism,and complication rates were compared between the *** The colloidal fluid dosage,total infusion,and urine volume,as well as time to first exhaust,time to food intake,and postoperative length of hospital stay,were lower in the observation group(P0.05).Compared with the control group,in the ob-servation group the lactic acid level was lower immediately after the surgery(P<0.05);the Mini-Mental State Examination score was higher on postoperative day 3(P<0.05);the pulse pressure variability(PPV)was lower at 30 min after pneumoperitone

关键词： Radical resection of rectal cancer Goal-directed fluid therapy Preoperative glucose load Cognitive condition Complication

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Improving Thermal-oxidative Aging Resistance of Styrene-butadiene Rubber by Antioxidant Loaded Silica Aerogel

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chinese Journal of Polymer Science 2024年第8期42卷 1198-1209页

作者： Xue-Fei Ping Yu wang Lu Liu Fu-yong Liu Hong-Wei He Pi wang wen-wen Yu Qiang Zheng College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030032China Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China

The antioxidant N-isopropyl-N'-phenyl-p-phenylenediamine(4010NA)was dissolved in ethanol and impregnated into silica aerogel(SAG)via vacuum-pressure cycles,yielding composite particles(A-N)with enhanced sustained-release and reinforcing *** effect of A-N on the mechanical properties and thermal-oxidative aging resistance of styrene-butadiene rubber(SBR)vulcanizates was *** and BET assessments indicated that the loading efficiency of 4010NA in SAG reached 14.26%within ethanol's solu bility *** A-N into SBR vulcanizates significantly elevated tensile strength by 17.5%and elongation at break by 41.9%over those with fumed silica and ***,A-N notably enhanced the thermal-oxidative aging resistance of *** aging for 96 h at 100℃,the tensile strength and elongation at break of SBR with A-N sustained 70.09%and 58.61%of their initial values,respectively,with the retention rate of elongation at break being 62.8%higher than that of SBR with fumed silica and free *** study revealed that A-N composite particles significantly inhibited the crosslinking in SBR's molecular chains,reducing hardening and embrittlement during later thermal-oxidative aging stages.

关键词： Styrene-butadiene rubber Silica aerogel Loading modification Thermal-oxidative aging

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Effect of post rolling stress on phase transformation behavior of microalloyed dual phase steel

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Journal of Iron and Steel Research International 2024年第3期31卷 688-699页

作者： wen-quan Sun Sheng-yi yong Tie-heng Yuan ting-song Yang An-rui He Chao Liu Rui-chun Guo National Engineering Research Center for Advanced Rolling and Intelligent Manufacturing University of Science and Technology BeijingBeijing 100083China

The slow phase transformation of microalloyed dual phase steel makes the nonuniform stress and temperature fields during the post rolling cooling process have a significant impact on the phase transformation *** the relatively slow phase transformation of DP780 steel within the microalloyed dual phase steel series,the influence of stress on the phase transformation behavior of DP780 steel was *** quantify the nonuniform thermal and stress conditions in the steel coil,a thermo-mechanical coupled finite element model of the hot-rolled strip cooling process was *** on the simulation data,DP780 steel was chosen as the research material,and Gleeble 3500 thermal simulation equipment was used for experimental *** thermal expansion curves were analyzed through regression to establish the dynamic model of DP780 steel phase transformation under ***,metallographic analysis was conducted to determine phase transformation type and grain size of DP780 *** results confirmed that the stress promotes the occurrence of semi-diffusion-type bainite ***,an appropriate level of stress facilitates the growth of bainitic grains,while the increased stress inhibits the growth of ferritic grains.

关键词： Microalloyed dual phase steel Stress Bainitic transformation Grain Finite element method

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Mesenchymal-epithelial transition factor amplification correlates with adverse pathological features and poor clinical outcome in colorectal cancer

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1395-1406页

作者： Qiu-Xiao Yu Ping-Ying Fu chi Zhang Li Li wen-ting Huang Department of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeShenzhen 518116Guangdong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is the third most common cancer and the second most common cause of cancer-related mortality ***-epithelial transition factor(MET)gene participates in multiple tumor biology and shows clinical potential for pharmacological manipulation in tumor *** amplification has been reported in CRC,but data are very *** pathological values of MET in CRC may provide new therapeutic and genetic screening options in future clinical *** To determine the pathological significance of MET amplification in CRC and to propose a feasible screening *** A number of 205 newly diagnosed CRC patients undergoing surgical resection without any preoperative therapy at Shenzhen Cancer Hospital of chinese Academy of Medical Sciences were *** patients were without RAS/RAF mutation or microsatellite *** amplification and c-MET protein expression were analyzed using fluorescence in situ hybridization(FISH)and immunohistochemistry(IHC),*** between MET aberration and pathological features were detected using the chi-squared *** free survival(PFS)during the two-year follow-up was detected using the Kaplan-Meier method and log rank *** results of MET FISH and IHC were com pared using one-way *** Polysomy-induced MET amplification was observed in 14.4%of cases,and focal MET amplification was not ***-induced MET amplification was associated with a higher frequency of lymph node metastasis(LNM)(P<0.001)and higher tumor budding grade(P=0.02).In the survival analysis,significant difference was detected between patients with amplified-and non-amplified MET in a two-year follow-up after the first diagnosis(P=0.001).C-MET scores of 0,1+,2+,and 3+were observed in 1.4%,24.9%,54.7%,and 19.0%of tumors,respectively.C-MET overexpression correlated with higher frequency of LNM(P=0.002),but no significant difference of PFS was dete

关键词： Colorectal cancer MET Amplification Pathological features Prognosis Fluorescence in situ hybridization

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Nanophase separated,grafted alternate copolymer styrene-maleic anhydride as an efficient room temperature solid state lithium ion conductor

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chinese Chemical Letters 2024年第7期35卷 491-496页

作者： Qian wang ting Gao Xiwen Lu Hangchao wang Minggui Xu Longtao Ren Zheng Chang wen Liu Institute of Science and Technology China Three Gorges CorporationBeijing 100038China State Key Laboratory of Chemical Resource Engineering Beijing Advanced Innovation Center for Soft Matter Science and EngineeringCollege of ChemistryBeijing University of Chemical TechnologyBeijing 100029China

All solid-state lithium metal batteries(ASSLMBs)based on polymer solid electrolyte and lithium metal anode have attracted much attention due to their high energy density and intrinsic ***,the low ionic conductivity at room temperature and poor mechanical properties of the solid polymer electrolyte result in increased polarization and poor cycling stability of the Li metal *** order to improve the ionic conductivity at room temperature while maintaining mechanical strength,we combine the conductivity of short chain polyethylene oxide(PEO)and strength of styrene-maleic anhydride copolymer(SMA)to obtain a grafted block copolymer with nanophase separation structure,which has room temperature ionic conductivity up to 1.14×10^(-4)S/cm and tensile strength up to 1.4 ***||Li symmetric cell can work stably for more than 1500 h under the condition of 0.1 mA/cm^(2).Li||LiFePO_(4)full cells can deliver a high capacity of 151.4 mAh/g at 25℃and 0.2 C/0.2 C charge/discharge conditions,showing 85.6%capacity retention after 400 ***,the all solid state Li||LiFePO_(4)pouch cell shows excellent safety performance under different abuse *** results demonstrate that the nanophase separated,grafted alternate copolymer electrolyte has huge potential for application in Li metal batteries.

关键词： Solid polymer electrolyte All solid-state battery Li metal battery Copolymers Nanophase separation

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A new insight into LPSO phase transformation and mechanical properties uniformity of large-scale Mg-Gd-Y-Zn-Zr alloy prepared by multi-pass friction stir processing

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Journal of Magnesium and Alloys 2024年第5期12卷 2041-2056页

作者： Xiaohu Guan wen wang ting Zhang Pai Peng Qiang Liu Peng Han Ke Qiao Jun Cai Liqiang wang Kuaishe wang School of Metallurgical Engineering National and Local Joint Engineering Research Center for Functional Materials ProcessingXi’an University of Architecture and TechnologyNo.13 Yanta RoadXi’anShaanxi 710055China Xi’an Rare Metal Materials Institute Co.Ltd Xi’an 710016China State Key Laboratory of Metal Matrix Composites School of Material Science and EngineeringShanghai Jiao Tong UniversityNo.800 Dongchuan RoadShanghai 200240China

A large-scale fine-grained Mg-Gd-Y-Zn-Zr alloy plate with high strength and ductility was successfully prepared by multi-pass friction stir processing(MFSP)technology in this *** structure of grains and long period stacking ordered(LPSO)phase were characterized,and the mechanical properties uniformity was ***,a quantitative relationship between the microstructure and tensile yield strength was *** results showed that the grains in the processed zone(PZ)and interfacial zone(IZ)were refined from 50μm to 3μm and 4μm,respectively,and numerous original LPSO phases were *** IZ,some block-shaped 18R LPSO phases were transformed into needle-like 14H LPSO phases due to stacking faults and the short-range diffusion of solute *** severe shear deformation in the form of kinetic energy caused profuse stacking fault to be generated and move rapidly,greatly increasing the transformation rate of LPSO *** MFSP,the ultimate tensile strength,yield strength and elongation to failure of the large-scale plate were 367 MPa,305 MPa and 18.0% *** refinement and LPSO phase strengthening were the major strengthening mechanisms for the MFSP *** particularly,the strength of IZ was comparable to that of PZ because the strength contribution of the 14H LPSO phase offsets the lack of grain refinement strengthening in *** result opposes the widely accepted notion that IZ is a weak region in MFSP-prepared large-scale fine-grained plate.

关键词： Friction stir processing Multi-pass Mg-Gd-Y-Zn-Zr alloy LPSO phase transformation Mechanical properties

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Characteristics of super drought in Southwest china and the associated compounding effect of multiscalar anomalies

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Science china Earth Sciences 2024年第7期67卷 2084-2102页

作者： Lin wang wen CHEN Gang HAUNG ting wang Qiulin wang Xiaoyun SU Zixuan REN Chakrit CHOTAMONSAK Atsamon LIMSAKUL Kritanai TORSRI CAS Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Heavy Rain and Drought-Flood Disasters in Plateau and Basin Key Laboratory of Sichuan Province Chengdu 610072China Department of Atmospheric Science Yunnan UniversityKunming 650500China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Carbon Neutrality Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Hangzhou Meteorological Bureau Hangzhou 310051China Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Geography Faculty of Social SciencesChiang Mai UniversityChiang Mai 50200Thailand Environmental Science Research Center Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Climate Change and Environmental Research Center TechnopolisKlong 5Klong LuangPathumthani 12120Thailand Hydro-Informatics Innovation Division Hydro-Informatics InstituteMinistry of Higher EducationScienceResearch and InnovationBangkok 10900Thailand

In recent decades,Southwest china(SWC)has suffered from frequent super droughts,leading to severe economic losses and ecological *** study investigates the characteristics of super droughts in SWC during 1961-2022,reveals the compounding effect of multiscalar anomalies,and explores the plausible atmospheric circulation mechanisms *** nature of super drought is a compound drought caused by the superposition of extreme drought events across multiple time *** contrasting the typical drought cases in 2006 and 2022,the decisive role of multiscalar drought compounding is *** on the Comprehensive Multiscalar Index(CMI),multiple super drought events in SWC were identified to be temporally clustered during *** them,the decadal background of enhanced evaporation and precipitation deficit at long time scales is a necessary condition for shaping the overall pattern of super droughts,while the precipitation and evaporation anomalies at short time scales trigger the outbreak of super droughts,determining the exact timing of *** events include August-September 2006,November 2009 to May 2010,July-October 2011,April-May 2012,January-April 2013,*** results suggest that the contribution of superposed precipitation anomalies to super drought is 2.4 times that of *** regards the circulation mechanisms affecting multiscalar precipitation,the anomalous spatial patterns at short-term and long-term scales are similar,featuring the cyclonic circulation over the South china Sea and the northeasterly wind anomalies together with the subsidence center over *** 2006-2014,the possible causes for the cross-seasonal persistent precipitation reduction in SWC are the extreme negative phase of the Pacific Decadal Oscillation(PDO)in the North Pacific as well as the pronounced warming of the warm pool in the western *** key dynamic processes are outlined as *** the one hand,the negative PDO p

关键词： Super drought Multiscalar Compounding effect Mechanism analysis Southwest china

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A Study of 10 Rotating Radio Transients Using Parkes Radio Telescope

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Research in Astronomy and Astrophysics 2024年第4期24卷 114-123页

作者： Xinhui Ren Jingbo wang wenming Yan Jintao Xie Shuangqiang wang Yirong wen yong Xia Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of chinese Academy of Sciences Beijing 100049China Institute of Optoelectronic Technology Lishui UniversityLishui 323000China Xinjiang Key Laboratory of Radio Astrophysics Urumqi 830011China Research Center for Intelligent Computing Platforms Zhejiang LaboratoryHangzhou 311100China

Rotating Radio Transients(RRATs)are a relatively new subclass of pulsars that emit detectable radio bursts *** analyzed 10 RRATs observed using the Parkes telescope,with eight of these observed via the ultra-wide-bandwidth low-frequency(UWL)*** measured the burst rate and produced integrated profiles spanning multiple frequency bands for three *** also conducted a spectral analysis on both integrated pulses and individual pulses of three *** of their integrated pulses follow a simple power law,consistent with the known range of pulsar spectral *** average spectral indices of single pulses are-0.9,-1.2,and-1.0 respectively,which are within the known range of pulsar spectral ***,we find that the spreads of single-pulse spectral indices for these RRATs(ranging from-3.5 to+0.5)are narrower compared to what has been observed in other ***,the average spectral index and scatter of single pulses are both relatively *** the remaining five RRATs observed at the UWL receiver,we also provide the upper limits on fluence and flux *** addition,we obtain the timing solution of PSR *** analysis shows that PSRs J1919+1745,J1709-43,and J1649-4653 are potentially nulling pulsars or weak pulsars with sparse strong pulses.

关键词： (stars:)pulsars:general stars:neutron stars:individual(PSRs J1919+1745.1909+0641,0628+0909)

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Abnormal grain growth induced byδ→γphase transformation in Fe-based shape memory alloys

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Journal of Materials Science & Technology 2024年第5期172卷 196-201页

作者： Huabei Peng Liqiu yong Gaixia wang Jiazhen Yan Bing Xu Yuhua wen School of Mechanical Engineering Sichuan UniversityChengdu 610065China Science and Technology on Reactor Fuel and Materials Laboratory Nuclear Power Institute of ChinaChengdu 610041China

Grain boundaries,including low-angle,high-angle,and coinci-dence boundaries,are intrinsic interfaces in polycrystalline *** heat-treatment at sufficiently high temperatures,grain boundary migration occurs because the grain boundaries are ther-modynamically ***,grain growth occurs due to a decrease in grain boundary area after heat-treatment[1].In general,there are two types of grain growth:normal grain growth,where grains grow uniformly,and abnormal grain growth,where one or a few grains selectively grow and engulf surround-ing smaller grains,leading to the formation of large grains,some-times several millimeters or greater in size[2].The classical tech-nique to achieve abnormal grain growth is the strain-annealing method,which involves subjecting the material to a small strain followed by annealing[3,4].This method has been reported to ob-tain single-crystal wires or plates[1].Additionally,abnormal grain growth can be achieved by plastic straining at high temperatures,resulting in the fabrication of large grains or single crystals[5].However,the above methods are not applicable to components with complicated shapes due to the inevitable deformation ***,Omori et *** a simply method of abnor-mal grain growth to fabricate ultra-large grains,even single crys-tals,in Cu-Al-Mn[1],Fe-Mn-Al-Ni[2],and Fe-Mn-Al-Ni-Cr[6]*** method involves applying cyclic heat treatment between a high temperature BCC single-phase region and a low tempera-ture BCC+FCC two-phase region[1,2,6-12].Note that the cyclic heat treatment resulted in the formation of BCC sub-grain struc-tures responsible for abnormal grain growth[1,2,6-12].In addition,Yang et *** that abnormal grain growth occurred at above 900℃,and large-grains,even single crystals,were obtained only through annealing cast Cu-based polycrystalline alloys contained coherent nano-particles[13,14].Notably,the cyclic heat treatment and annealing cast alloys are deform

关键词： grain alloys deformation

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A passive wireless surface acoustic wave(SAW)sensor system for detecting warfare agents based on fluoroalcohol polysiloxane film

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Microsystems & Nanoengineering 2024年第1期10卷 67-78页

作者： yong Pan Cancan Yan Xu Gao Junchao Yang Tengxiao Guo Lin Zhang wen wang State Key Laboratory of NBC Protection for Civil Beijing 102205China Institute of Acoustics Chinese Academy of SciencesBeijing 100190China The School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China

Long-term monitoring of environmental warfare agengts is a challenge for chemical gas *** address this issue,we developed a 433 MHz passive wireless surface acoustic wave(WSAW)gas sensor for dimethyl methylphosphonate(DMMP)*** WSAW gas sensor includes a YZ lithium niobate(LiNbO_(3))substrate with metallic interdigital transducers(IDTs)etched on it,and an antenna was placed near the IDT.A DMMP-sensitive viscoelastic polymer fluoroalcoholpolysiloxane(SXFA)film was prepared on a LiNbO_(3) substrate,and mode modeling coupling was used to optimize the design *** sensor can function properly in an environments between−30℃ and 100℃ with humidity less than 60%*** the wireless transmission distance was within the range of 0-90 cm,the sensor noise increased with distance,and the stability was less than 32°/*** optimizing the film thickness of SXFA,a relationship was observed between sensor sensitivity and film *** the film thickness of SXFA reached 450 nm,the optimal value was *** a distance of 20 cm between the transmitting and receiving antennas,DMMP was detected at different concentrations with the developed WSAW gas *** lower detection limit of DMMP was 0.48 mg/m^(3),the sensitivity of the sensor was 4.63°/(mg/m^(3)),and repeatable performance of the sensor was confirmed.

关键词： film alcohol passive

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