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Neuropsychiatric Symptoms and Cognitive Impairment in Chinese Patients with Parkinson's Disease in Han and Hui Ethnicity

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Current Medical Science 2019年第1期39卷 122-126页

作者： Mei-ling YAO Hong ZHANG Yan XU Sheng-ming ZHANG yong-zhe gao Min SHU Jun-Jian ZHANG Department of Neurology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Teaching and Research Section of Neuropsychiatry Zhongnan Hospital of Wuhan UniversityWuhan 430071China

Nenropsychiatric symptoms are common in patients with Parkinson's disease(PD)and they are likely to outweigh the motor symptoms and become a major factor affecting the quality of life of PD ***,the studies focusing on the non-motor symptoms in Chinese PD patients from different ethnicity are *** aim of this retrospective study was to investigate neuropsychiatric symptoms and cognitive impairment in Chinese PD patients from Han and Hui populations from central ***-two Han Chinese PD patients(Han PD group)and 71 age-and sex-matched Hui Chinese PD patients(Hui PD group)were enrolled from Zhongnan Hospital of Wuhan University between Sept.2011 and Aug.2014 in the *** neuropsychiatric symptoms and cognitive impairment were assessed using Neuropsychiatric Inventory(NPI)and Mini Mental State Examination(MMSE).We found that the proportion of depression,anxiety,apathy,irritability,euphoria and night time behavior disturbances were higher in the Han PD group than in the Hui PD group(P0.05).The total mean scores of the MMSE from patients in the Han PD group were similar to those in the Hui PD group(P>0.05).However,the subscale scores of recall domain and language domain in the Han PD group were significantly different from those in the Hui PD group(P0.05).This study first showed the recall domain and language domain were different between the Han PD patients and the Hui PD ***,anxiety,apathy,irritability,euphoria and night time behavior disturbances were less presented in the Hui PD *** these differences may be related to the different ethnicity,which would be helpful for clinical physici

关键词： Parkinson's disease neuropsychiatric symptoms cognitive impairment Han Chinese Hui Chinese

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Recent Advances in Fibrous Materials for Hydroelectricity Generation

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Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo Xu Xiao Feng Xing Yang zheheng Song Yuhang Song Jingyu Chen Yingcun Liu Chong gao yong Du zhe Sun Weilin Xu Jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

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The role of TGF-β1/Smad/CTGF pathway in The Fibrous-Muscular Alterations of Corpus Cavernosum Related to Streptozotocin-Induced Diabetic

The role of TGF-β1/Smad/CTGF pathway in The Fibrous-Muscula...

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第七次全国中西医结合男科学术会议及全国中西医结合男科提高班

作者： Feng ZHOU~1,Guang-yong LI,zhe-zhu gao,Tao LIU,Hua XIN,Wei-ren LI, Wan-shou CUI,and Zhong-cheng XIN~(1*) From the 1 Andrology Center,Peking University First Hospital,Beijing,China

In this study,we investigated the pathological changes of extracellular matrix in the corpus cavernosum of streptozotocin(STZ)-induced diabetes rats,and examined the mechanisms underlying changes in mechanical properties of the penile erection due to diabetic erectile dysfunction(ED),the role of TGF-β1/Smad/CTGF *** 8-week-old Sprague-Dawley rats were used and randomly divided into control and diabetic groups. Diabetes was induced by an intraperitoneal injection of STZ(60mg/kg).Eight weeks later, the erectile function was measured by electrical stimulation of the cavernous nerve by MP150 *** penis was harvested and histological examination(Masson’s trichrome stain,picrosirius red stain,Harts elastin stain and immunohistochemical stain) and western blot were performed followed by Intracavernous pressure(ICP) /mean arterial pressure (MAP) *** significantly attenuated the erectile responses with decreased corpus cavernosum(CO smooth muscle/collagen *** collagen fibersⅠ/Ⅲratio was signi? cantly higher in diabetic rats than in *** elastic fibers manifest as fragmentation in diabetic rats,the length was ***-β1/Smad/CTGF signaling pathway was up-regulated in the penis from diabetic *** with that in control rats,P-Smad2 expression was higher mainly in smooth muscle cells and broblasts of diabetic rats;the apoptotic index was higher in diabetic rats,compared with the control group. The up-regulation of TGF-β1/Smad/CTGF signaling pathway in the penis of diabetic rats might play an important role in diabetes-induced structural changes and deterioration of erectile function.

关键词： Erectile Dysfunction Diabetes Corpus Cavernosum Smooth Muscle Elastic Fibers Collagen Fibers Transforming Growth Factor-beta Smad Connective Tissue Growth Factor

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Assessing the corrosion protection property of coatings loaded with corrosion inhibitors using the real-time atmospheric corrosion monitoring technique

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 119-126页

作者： Xiaoxue Wang Lulu Jin Jinke Wang Rongqiao Wang Xiuchun Liu Kai gao Jingli Sun yong Yuan Lingwei Ma Hongchang Qian Dawei Zhang School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Institute of Space Long March Vehicle Beijing 100076China National Materials Corrosion and Protection Data Center University of Science and Technology BeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal ***,limited studies have applied ACM to the corrosion protection properties of organic *** study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over *** with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in *** the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy *** trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface *** alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic *** with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.

关键词： atmospheric corrosion monitoring technology corrosion inhibitor coating carbon steel corrosion protection

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Stable Model Order Reduction Method for Fractional-Order Systems Based on Unsymmetric Lanczos Algorithm

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IEEE/CAA Journal of Automatica Sinica 2019年第2期6卷 485-492页

作者： zhe gao the College of Light Industry Liaoning University

This study explores a stable model order reduction method for fractional-order systems. Using the unsymmetric Lanczos algorithm, the reduced order system with a certain number of matched moments is generated. To obtain a stable reduced order system, the stable model order reduction procedure is discussed. By the revised operation on the tridiagonal matrix produced by the unsymmetric Lanczos algorithm, we propose a reduced order modeling method for a fractional-order system to achieve a satisfactory fitting effect with the original system by the matched moments in the frequency domain. Besides, the bound function of the order reduction error is offered. Two numerical examples are presented to illustrate the effectiveness of the proposed method.

关键词： Fractional-order systems order reduction stable reduced order systems unsymmetric Lanczos algorithm

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Improved Oustaloup approximation of fractional-order operators using adaptive chaotic particle swarm optimization

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Journal of Systems Engineering and Electronics 2012年第1期23卷 145-153页

作者： zhe gao Xiaozhong Liao School of Automation Beijing Institute of Technology Beijing 100081 P. R. China

A rational approximation method of the fractional-order derivative and integral operators is proposed. The turning fre- quency points are fixed in each frequency interval in the standard Oustaloup approximation. In the improved Oustaloup method, the turning frequency points are determined by the adaptive chaotic particle swarm optimization （PSO）. The average velocity is proposed to reduce the iterations of the PSO. The chaotic search scheme is combined to reduce the opportunity of the premature phenomenon. Two fitness functions are given to minimize the zero-pole and amplitude-phase frequency errors for the underlying optimization problems. Some numerical examples are compared to demonstrate the effectiveness and accuracy of this proposed rational approximation method.

关键词： fractional-order calculus rational approximation particle swarm optimization (PSO) tent map.

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High densities of magnetic nanoparticles supported on graphene fabricated by atomic layer deposition and their use as efficient synergistic microwave absorbers

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Nano Research 2014年第5期7卷 704-716页

作者： Guizhen wang zhe gao Gengping Wan Shiwei Lin Peng Yang yong Qin State Key Laboratory of Coal Conversion Institute of Coal Chemistry Chinese Academy of Sciences Taiyuan 030001 China University of Chinese Academy of Sciences Beijing 100039 China Key Laboratory of Chinese Education Ministry for Tropical Biological Resources Hainan University Haikou 570228 China

An atomic layer deposition （ALD） method has been employed to synthesize Fe3O4/graphene and Ni/graphene composites. The structure and microwave absorbing properties of the as-prepared composites are investigated. The surfaces of graphene are densely covered by Fe3O4 or Ni nanoparticles with a narrow size distribution, and the magnetic nanoparticles are well distributed on each graphene sheet without significant conglomeration or large vacancies. The coated graphene materials exhibit remarkably improved electromagnetic （EM） absorption properties compared to the pristine graphene. The optimal reflection loss （RL） reaches -46.4 dB at 15.6 GHz with a thickness of only 1.4 mm for the Fe3O4/graphene composites obtained by applying 100 cycles of Fe2O3 deposition followed by a hydrogen reduction. The enhanced absorption ability arises from the effective impedance matching, multiple interfacial polarization and increased magnetic loss from the added magnetic constituents. Moreover, compared with other recently reported materials, the composites have a lower filling ratio and smaller coating thickness resulting in significantly increased EM absorption properties. This demonstrates that nanoscale surface modification of magnetic particles on graphene by ALD is a very promising way to design lightweight and high-efficiency microwave absorbers.

关键词： atomic layer deposition(ALD) graphene magnetic nanoparticles microwave absorption

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Extraordinary mechanical performance in charged carbyne

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Chinese Physics B 2022年第12期31卷 559-565页

作者： yong-zhe Guo yong-Heng Wang Kai Huang Hao Yin En-Lai gao Department of Engineering Mechanics School of Civil EngineeringWuhan UniversityWuhan 430072China

Carbyne,the linear chain of carbon,promises the strongest and toughest material but possesses a Peierls instability(alternating single-bonds and triple-bonds)that reduces its strength and ***,we computationally found that the gravimetric strength,strain-to-failure,and gravimetric toughness can be improved from 74 GPa·g^(-1)·cm^(3),18%,and 9.4 k J·g^(-1)for pristine carbyne to the highest values of 106 GPa·g^(-1)·cm^(3),26%,and 19.0 k J·g^(-1)for carbyne upon hole injection of+0.07 e/atom,indicating the charged carbyne with record-breaking mechanical *** on the analyses of the atomic and electronic structures,the underlying mechanism behind the record-breaking mechanical performance was revealed as the suppressed and even eliminated bond alternation of carbyne upon charge injection.

关键词： charged carbyne first-principles calculations strength and toughness bond alternation

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Effect of background fluctuation on velocity diagnostics by Mach probe

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Plasma Science and Technology 2020年第12期22卷 31-36页

作者： Yunxiao WEI zhe gao Department of Engineering Physics Tsinghua UniversityBeijing 100084People's Republic of China

The effect of background fluctuation on velocity diagnostics is discussed and studied. The kinetic theory of Mach probe(MP) and the theory of BGK mode are combined to evaluate how the measurement of MP is affected by electrostatics fluctuation. It is found that the quantity of speed by the MP model is closer to the effective velocity in the picture of momentum flux rather than the real mean velocity, while, with high fluctuation, the fitting parameter of MP's exponential formula should be corrected.

关键词： velocity diagnostics Mach probe electrostatic fluctuation

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Modified constriction particle swarm optimization algorithm

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Journal of Systems Engineering and Electronics 2015年第5期26卷 1107-1113页

作者： zhe Zhang Limin Jia yong Qin Traffic and Transportation School Beijing Jiaotong University State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong University Beijing Research Center of Urban Traffic Information Sensing and Service Technologies Beijing Jiaotong University

To deal with the demerits of constriction particle swarm optimization(CPSO), such as relapsing into local optima, slow convergence velocity, a modified CPSO algorithm is proposed by improving the velocity update formula of CPSO. The random velocity operator from local optima to global optima is added into the velocity update formula of CPSO to accelerate the convergence speed of the particles to the global optima and reduce the likelihood of being trapped into local optima. Finally the convergence of the algorithm is verified by calculation examples.

关键词： particle swarm optimization random speed operator convergence global optima

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