检索结果-南通市图书馆

Granulation Tissue-type Hemangioma in the Internal Jugular Vein

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第3期131卷 364-365页

作者： Jian-Hui Li yong-yi yuan Jing yuan De-Liang Huang Ming-Bo Liu Department of Otolaryngology Hainan Branch of PLA General Hospital Sanya Hainan 572000 China Department of Otolaryngology Head and Neck Surgery Chinese PLA General Hospital Beijing 100853 China Department of Pathology Chinese PLA General Hospital Beijing 100853 China

Granulation tissue-type hemangiomas are rare benign vascular lesions that mainly affect the head,neck,and *** 75% of the cases,the lesion shows a striking predilection for the mucosa,while skin is the second common site for the *** tissue-type hemangiomas occur upon various stimuli such as chronic low-grade irritation,traumatic injury,and hormonal *** lesions occur predominantly in young females,possibly triggered by a vascular effect due to hormonal *** range in size from a few millimeters to several centimeters and can grow rapidly with frequently *** purpose of this article is to present a case of granulation tissue-type hemangioma and to briefly review the current literature for this condition.

关键词：

Systematic study of the transfer of amino acids across the water/1,2-dichloroethane interface facilitated by dibenzo-18-crown-6

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2004年第1期47卷 24-33页

作者： CHEN yong, yuan yi, ZHANG Meiqin, LI Fei, SUN Peng, GAO Zhao & SHAO yuanhuaState Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun China College of Chemistry and Molecular Engineering Peking University Beijing China

Facilitated ion transfer reactions of 20 amino acids with dibenzo-18-crown-6 (DB18C6) at the water/1,2-dichloroethane (W/DCE) interfaces supported at the tips of micro- and nano-pipets were investigated systematically using cyclic voltammetry. It was found that there were only 10 amino acids, that is, Leu, Val, lie, Phe, Trp, Met, Ala, Gly, Cys, Gin (in brief), whose protonated forms as cations can give well-defined facilitated ion transfer voltammograms within the potential window, and the reaction pathway was proven to be consistent with the transfer by interfacial complexation/dissociation (TIC/TID) mechanisms. The association constants of DB 18C6 with different amino acids in the DCE (β0), and the kinetic parameters of reaction were evaluated based on the steady-state voltammetry of micro- or nano-pipets, respectively. The experimental results demonstrated that the selectivity of complexation of protonated amino acid by DB18C6 compared with that of alkali metal cations was low, which can be attributed to the vicinal effect arising from steric hindrance introduced by their side group and the steric bulk effect by lipophilic stabilization. Moreover, the association constants and the standard rate constants for different amino acids showed good correlations with their hydrophobicity (π), except Gly and Met, which inferred that the selectivity of such heterogeneous complex reaction for different amino acids with DB18C6, was not only affected by discrimination in binding these ions to the crown ether macro-cycle, but also significantly modified by the ion transfer Gibbs energy which was closely related to the structure of the transferred ions, protonated amino acids.

关键词： micro-/nano-pipet, water/1,2-dichloroethane interface, facilitated ion transfer, cyclic voltammetry, amino acid.

In Vitro Cultivation of Cells from Cercariae of Schistosoma japonicum

在线全文

学校读者我要写书评

暂无评论

In Vitro Cultivation of Cells from Cercariae of Schistosoma ...

Succeeded in vitro cultivation of cells from cercariae of Schistosoma japonicum

中国动物学会第八次全国寄生虫学学术讨论会

作者： ZHANG Zhong-yong, yi Xin-yuan, ZENG Xian-fang, LI Jing-ruLaboratory of Schistosomiasis, Xiangya Medical Collage,Central South University Changsha 410078, China

＜正＞ The ability to propagate parasites cells in vitro has proven to be a boon for studies in molecular、cellular、and developmental biology,pharmacology、immunology,and other areas,yet it has remeined aninsurmountable problem for certain *** parasites,many of which require more than onehost species for the completion of their life cycles,are particularly difficult in this *** on thesuccessful establishment of Cysticerous cellulosae cell line,we have recently made an effort to explore thepossibility of in vitro cultivation of Schistosoma japonicum cercaria *** are now reporting thepreliminary success in this regard.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Succeeded in vitro cultivation of cells from cercariae of Sc...

Endogenous/exogenous dual stimulation“ROS engineering”amplification combined with autophagy-augmented for efficient ferroptosis therapy

中国动物学会第八次全国寄生虫学学术讨论会

作者： ZHANG Zhong-yong, yi xin-yuan, ZENG xian-fang, LI Jing-ru(Laboratory of Schistosomiasis, Xiangya Medical Collage, Central South University Changsha410078,China)

＜正＞ with the intent of providing a useful technique for studies on the cellular engineeringof Schistosoma japonicum,we have attempted to establish indefinitely proliferating cell *** ability topropagate parasites cells in vitro has proven to be a boon for studies in molecular、cellular、anddevelopmental biology,pharmacology、immunology,and other areas,yet it has remained aninsurmountable problem for certain *** parasites,many of which require more than 1 hostspecies for the completion of their life cycles,are particularly difficult to provide the means to propagate

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 597-606页

作者： Pengye Du Pengpeng Lei yuan Liang Ran An yi Wei Shuyu Liu Jianhao Zheng Hongjie Zhang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Chemistry Tsinghua UniversityBeijing 100084China

“Reactive oxygen species(ROS)engineering”is one of the most promising anti-tumor treatments developed in recent *** explosion of ROS will cause oxidative stress,thereby inducing tumor cell ***,ROS accumulation in tumor cells is eliminated by endogenous cellular self-regulation *** this work,a kind of endogenous/exogenous dual stimulation nanoagent noted as UMZC is *** reaction occurs between NH_(2)-MIL-88B(Fe)contained in UMZC and the overexpression of endogenous H_(2)O_(2)to generate ROS,amplified by endogenous H_(2)S of colon tumor *** addition,NH_(2)-MIL-88B(Fe)also functions to deplete glutathione(GSH)for stopping it from consuming *** nanoparticles at the core of UMZC convert near-infrared into visible light,which excites zinc phthalocyanine to initiate the photochemical reaction that generates more ROS,thus alleviating the lack of tissue penetration depth for visible *** agonist chitosan oligosaccharides induce enhancement of cellular autophagy for disrupting cellular metabolic stress and the resistance to oxidative stress of tumor cells,allowing“ROS engineering”to fully exert anti-tumor *** of ROS generation,GSH depletion,and induced cellular autophagy caused by nanoagents have promoting effects on the occurrence of ***,the nanoagents show the ability to effectively treat colon tumors.

关键词： reactive oxygen species(ROS)engineering upconversion nanoparticles cellular autophagy ferroptosis tumor therapy

Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin Jin yiming Qin Feifei yuan Hongbin Lu Jianzhong Hu yong Cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2

肾细胞癌患者行保留肾单位手术与根治性手术的效果及生活质量比较

在线全文

学校读者我要写书评

暂无评论

解放军医药杂志 2017年第9期29卷 59-62页

作者：王勇温元毅资阳市第一人民医院泌尿外科四川资阳641300

目的分析保留肾单位手术(NSS)与腹腔镜根治性肾切除术(RPRN)治疗肾细胞癌的效果及对生活质量的影响。方法选取2012年9月—2015年1月就诊的80例肾细胞癌患者,根据手术治疗方法分为RPRN组(n=40)、NSS组(n=40)。统计两组手术时间、出血量... 详细信息

目的分析保留肾单位手术(NSS)与腹腔镜根治性肾切除术(RPRN)治疗肾细胞癌的效果及对生活质量的影响。方法选取2012年9月—2015年1月就诊的80例肾细胞癌患者,根据手术治疗方法分为RPRN组(n=40)、NSS组(n=40)。统计两组手术时间、出血量、引流时间、术后下床时间、住院时间,检测术前、术后1年和2年的血肌酐水平,分析术后1年、2年的生存率与生活质量,生活质量采用中文版健康调查简表评分(SF-36)评估。结果NSS组下床时间、住院时间较RPRN组短(P0.05)。两组术后2年SF-36评分中生理功能、生理职能、情感职能和总体健康评分均较术后1年明显升高(P<0.05)。术后1年、2年,NSS组SF-36评分中生理功能、生理职能、精神健康、情感职能和总体健康评分均显著高于RPRN组(P<0.05)。结论 NSS治疗肾细胞癌在改善手术疗效、提高生存率、促进术后恢复等方面与RPRN类似,尤其能有效保护肾功能和提高术后生活质量。

关键词：肾肿瘤保留肾单位手术腹腔镜根治性肾切除术治疗效果生活质量

接触丙烯腈工人血中一氧化氮与一氧化氮合酶的变化

在线全文

学校读者我要写书评

暂无评论

复旦学报（医学版） 2005年第1期32卷 36-39页

作者：王卫群白永怿周元陵余竹元复旦大学附属金山医院心内科复旦大学附属金山医院中心实验室上海200540

目的探讨职业性接触丙烯腈对人体血管内皮功能的影响。方法以某石化厂从事腈纶纤维生产的 111名工人为接触组,条件相近的不接触任何毒物及不进行有害作业的健康体检者89人为对照组。进行血清一氧化氮代谢产物水平、血清总一氧化氮合... 详细信息

目的探讨职业性接触丙烯腈对人体血管内皮功能的影响。方法以某石化厂从事腈纶纤维生产的 111名工人为接触组,条件相近的不接触任何毒物及不进行有害作业的健康体检者89人为对照组。进行血清一氧化氮代谢产物水平、血清总一氧化氮合酶(tNOS)活力、血清诱导型一氧化氮合酶(iNOS)活力测定,作为评估血管内皮功能的指标。结果与对照组比较,接触组NO水平显著降低(P<0.01)。以NO水平为应变量,以接触丙烯腈、性别、年龄、家族史、吸烟量、饮酒量、血清三酰甘油等指标自变量,进行逐步多元线性回归分析。接触丙烯腈与血清NO水平呈显著负相关(P<0.01),且相关性随工龄的延长而增加。结论职业性接触丙烯腈可损害血管内皮功能,且这种损害可能具有累积效应。

关键词：血清 NO水平血管内皮功能一氧化氮合酶对照组人血职业性接触丙烯腈石化厂产物

Assessing the corrosion protection property of coatings loaded with corrosion inhibitors using the real-time atmospheric corrosion monitoring technique

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 119-126页

作者： Xiaoxue Wang Lulu Jin Jinke Wang Rongqiao Wang Xiuchun Liu Kai Gao Jingli Sun yong yuan Lingwei Ma Hongchang Qian Dawei Zhang School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Institute of Space Long March Vehicle Beijing 100076China National Materials Corrosion and Protection Data Center University of Science and Technology BeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal ***,limited studies have applied ACM to the corrosion protection properties of organic *** study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over *** with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in *** the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy *** trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface *** alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic *** with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.

关键词： atmospheric corrosion monitoring technology corrosion inhibitor coating carbon steel corrosion protection