检索结果-南通市图书馆

Efficacy of combined psychological and physical nursing in preventing peripherally inserted central catheter-related thrombosis in gastric cancer patients

引用

World Journal of Gastrointestinal Surgery 2025年第3期17卷 206-212页

作者： Wei-Jing Ni Yu-xiu xi yong-Chao Zhou Venous Therapy Nursing Clinic Affiliated Hospital of Jiangnan UniversityWuxi 214000Jiangsu ProvinceChina

BACKGROUND Long-term chemotherapy for patients with gastric cancer(GC),facilitated by peripherally inserted central catheter(PICC)catheterization,reduces vascular damage and enhances drug delivery efficiency but carries risks of catheter-related complications.A combination of group psychological nursing and physical mo-vement care significantly mitigates the risk of venous thrombosis and improves psychological well-being,and enhances motor function,underscoring its clinical *** To assess group psychological and physical movement nursing in preventing venous thrombosis in patients with PICC *** Sixty-five GC patients with PICC,admitted from January 2022 to January 2023,were randomly divided into two groups using the lottery method:A control group(n=35,routine nursing)and an observation group(n=30,routine nursing plus psychological nursing and physical movement nursing).Both groups re-ceived continuous care for 2 ***-nursing and post-nursing data on psycho-logical state,physical function,chemotherapy-related thrombosis incidence,and cancer-related fatigue were analyzed using SPSS 26.0 and GraphPad Prism *** After nursing,both groups showed reduced Hamilton Anxiety Scale scores and increased General Perceived Self-Efficacy Scale scores,with the observation group performing better(P<0.05).The Functional Comprehensive Assessment score for the observation group after nursing was(65.42±2.35)points,lower than the control group’s(62.19±4.33)points(P<0.05).Although no significant difference was observed in the incidence of venous thrombosis between the two groups(χ2=0.815,P=0.367),the observation group had lower *** groups showed decreased Revised Piper Fatigue Scale scores,with the observation group scoring lower(P<0.05).CONCLUSION Group psychological and physical movement nursing for patients with PICC reduces venous thrombosis risk,improves psychological well-being,cancer-related fatigue,and physical function,making it highly prom

关键词： Group psychological nursing Physical movement nursing Peripherally inserted central catheter Gastric cancer Venous thrombosis Cancer-related fatigue

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

使用SSE技术优化语音识别中的测度计算

引用

计算机工程与应用 2002年第8期38卷 85-86页

作者：汪俊杰赵勇肖熙王作英清华大学电子工程系北京100084

在语音识别中,测度计算占用了整个系统的绝大部分时间。文章介绍了利用SSE技术优化测度计算的方法,实验结果说明SSE技术能大幅提高系统的计算效率。

关键词：测度计算语音识别 SSE技术模板匹配计算机

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal[3+2]annulation

引用

Science China Chemistry 2025年第1期68卷 174-180页

作者： Fan-xiao Meng xing-Yu wang Ka Lu Ju-Song Yang Fu-Min Zhang Ai-Jun Ma Bao Du yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Biotechnology and Health Sciences Wuyi UniversityJiangmen 529020China

Herein,the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO)complex catalyze asymmetric formal[3+2]cycloaddition between quinones and ynamides is explored,producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent ***,density functional theory calculations were applied to explain the possible reaction mechanism.

关键词： benzofuran atropisomers novel de novo synthetic strategy asymmetric formal[3+2]cycladdition Cu/SPDO complex DFT calculations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ti_(3)C_(2)T_(x) Composite Aerogels Enable Pressure Sensors for Dialect Speech Recognition Assisted by Deep Learning

引用

Nano-Micro Letters 2025年第5期17卷 1-15页

作者： Yanan xiao He Li Tianyi Gu xiaoteng Jia Shixiang Sun yong Liu Bin wang He Tian Peng Sun Fangmeng Liu Geyu Lu State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012People’s Republic of China School of Integrated Circuits Tsinghua UniversityBeijing 100084People’s Republic of China International Center of Future Science Jilin UniversityChangchun 130012People’s Republic of China

Wearable pressure sensors capable of adhering comfortably to the skin hold great promise in sound ***,current intelligent speech assistants based on pressure sensors can only recognize standard languages,which hampers effective communication for non-standard language ***,we prepare an ultralight Ti_(3)C_(2)T_(x)MXene/chitosan/polyvinylidene difluoride composite aerogel with a detection range of 6.25 Pa-1200 k Pa,rapid response/recovery time,and low hysteresis(13.69%).The wearable aerogel pressure sensor can detect speech information through the throat muscle vibrations without any interference,allowing for accurate recognition of six dialects(96.2%accuracy)and seven different words(96.6%accuracy)with the assistance of convolutional neural *** work represents a significant step forward in silent speech recognition for human–machine interaction and physiological signal monitoring.

关键词： Pressure sensor Wearable sensor Ti_(3)C_(2)T_(x) composite aerogel Dialect speech recognition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flow and Heat Transfer of Hydrocarbon Fuel in a Channel with Staggered-Side-Gap Micro Ribs

引用

Journal of Thermal Science 2025年第02期 524-541页

作者： JIANG Yuguang QI yongjian wang Leqing LIN yong FAN Wei School of Power and Energy Northwestern Polytechnical University

SCRamjet is exposed to severe thermal environments during hypersonic flights,which poses a serious challenge to the engine cooling *** cooling with hydrocarbon fuel is considered promising,in which the hydrocarbon fuel flows through micro channels（200 μm-3 mm） to absorb the combustion heat *** strictly limited hydrocarbon fuel onboard,heat transfer deterioration and over-temperature are highly *** this paper,micro ribs with staggered side gaps are introduced and numerically studied to enhance the heat *** with the straight channel and channel with straight micro ribs,the staggered side gaps alleviate the local low velocity zone and intensify the longitudinal and transverse *** heat transfer is obviously *** rib height enhances the heat transfer by stronger side gap effects at the cost of larger pressure *** best overall heat transfer factor η is achieved in the case of hrib/H=0.1,which increases by 204.5% comparing to the straight *** the rib interval is too small or too large,it approaches to the straight *** best overall heat transfer factor η is achieved in the case of L/prib=100,which increases by212.9% comparing to the straight *** is known the improvement in the geometry of the ribs,i.e.,the staggered-side-gap micro ribs,induces extra transverse vortex and improves the heat transfer performance more *** research of this paper provides support for the cooling design of the SCRamjet.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Early Paleozoic Tectonic Evolution of the Chinese Southwest Tianshan Orogen:Implications from Detrital Zircon U-Pb Geochronology of the Biedieli Sedimentary Rocks,Northern Wushi Area,NW China

引用

Acta Geologica Sinica(English Edition) 2025年第1期99卷 38-52页

作者： HUO Hailong CHEN Zhengle ZHANG Qing HAN Fengbin ZHANG Wengao wang yong wang Wenbao Laboratory of Dynamic Diagenesis and Metallogenesis Institute of GeomechanicsChinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Paleomagnetism and Tectonic Reconstruction of Ministry of Natural Resources Beijing 100081China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100094China xinjiang Research Center for Mineral Resources Urumqi 830011China Hohhot Natural Resources Comprehensive Survey Center Hohhot 010020China

The Southwest Tianshan is the suture zone between the Central Tianshan and the Tarim *** better illustrate the subduction polarity of the Southwest Tianshan Ocean,a systematic detrital zircon LA-ICP-MS U-Pb geochronology of sedimentary rocks of the Devonian Apadaerkang Formation and the Carboniferous Akeqiayi Group of the Biedieli area in the Wushi region is the *** zircon ages indicate that the youngest grains of the targeted quartz sandstones are Late Devonian and Early Carboniferous in age,*** ages also have relatively similar age spectra,indicating a similar tectonic setting and source in the Biedieli area during the Devonian to *** main spectrum peaks occur at 2360,1960,810,640 and 440 Ma,with a principal age peak in the early Paleozoic(474-430 Ma),and the Central Tianshan Terrane is indicated as the main *** detrital zircon geochronology and sedimentary characteristics of the Biedieli rocks indicate that the Paleozoic sedimentary rocks in the northern Wushi region were formed at an active continental margin,associated mainly with the early Paleozoic subduction of the South Tianshan Ocean.

关键词： detrital zircon LA-ICP-MS U-Pb Wushi Southwest Tianshan

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reverse modulation of defect density of Ce-MOF-808 by solventassisted ligand exchange for dicyclopentadiene hydrogenation

引用

Science China Chemistry 2025年

作者： Danfeng Zhao Fajie Hu Rushuo Li xinmeng Xu Zhaokun wang Zuoshuai xi Jun Tong xiubing Huang Ge wang Advanced Innovation Center for Materials Genome Engineering Beijing Key Laboratory of Function Materials for Molecule & Structure Construction School of Materials Science and Engineering University of Science and Technology Beijing

Defect engineering is a pivotal strategy for tailoring the electronic structure and physicochemical properties of catalysts, yet the straightforward manipulation of defect density in porous materials presents a current challenge. In this work, we achieved precise control over the coordination unsaturated site（CUS） content and pore architecture of Ce-MOF-808 by employing 2-fluorobenzoic acid（2-FBA） as a modifier. Leveraging the p Kadisparities among three ligands（1,3,5-tricarboxylic benzoic acid,formic acid, and 2-FBA）, we preserved the spn topology of Ce-MOF within an aqueous system, while realizing partial substitution of the auxiliary ligands and saturation of the CUS. The amount of 2-FBA was negatively correlated with the number of ligand defects, and the consequent decrease in Ce3+content and the increase in the number of ligand linkages also induced crystal structure transformation. The modulation of the defect structure was correlated with the catalytic performance of dicyclopentadiene（DCPD） hydrogenation reaction, in which Ce-MMF0.15, constructed by the modulation of 0.15 mol amount of 2-fluorobenzoic acid, exhibited an optimal ligand defect density and micro-mesoporous structure, enabling almost complete conversion of DCPD at 100 ℃ and 2 MPa. This article also elucidates the correlation between the regulation of defect density and the accessibility of frustrated Lewis pair（FLP） active sites, guiding the application of novel porous intrinsic FLP materials in hydrogenation catalysis.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

引用

Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen xiaolin Zeng Le wang Wenwu Zhang Gang Li xing Cheng Peiqiang Su yong Wan xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Near-infrared brain functional characteristics of mild cognitive impairment with sleep disorders

引用

World Journal of Psychiatry 2025年第1期15卷 106-116页

作者： Heng Liao Sha Liao Yu-Jiao Gao xi wang Li-Hong Guo Su Zheng Wu Yang Yi-Nan Dai Sleep Psychosomatic Medicine Center Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Integrated Chinese and Western Medicine Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Orthopaedics Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Rehabilitation Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina

BACKGROUND Mild cognitive impairment(MCI)has a high risk of progression to Alzheimer’s *** disease is often accompanied by sleep disorders,and whether sleep disorders have an effect on brain function in patients with MCI is *** To explore the near-infrared brain function characteristics of MCI with sleep *** A total of 120 patients with MCI(MCI group)and 50 healthy subjects(control group)were *** subjects underwent the functional near-infrared spec-troscopy *** baseline data,Mini-Mental State Examination,Montreal Cognitive Assessment scale,fatigue severity scale(FSS)score,sleep parameter,and oxyhemoglobin(Oxy-Hb)concentration and peak time of functional near-infrared spectroscopy test during the task *** relationship between Oxy-RESULTS Compared with the control group,the FSS score of the MCI group was higher(t=11.310),and the scores of Pittsburgh sleep quality index,sleep time,sleep efficiency,nocturnal sleep disturbance,and daytime dysfunction were higher(Z=-10.518,-10.368,-9.035,-10.661,-10.088).Subjective sleep quality and total sleep time scores were lower(Z=-11.592,-9.924).The sleep efficiency of the MCI group was lower,and the awakening frequency,rem sleep latency period,total sleep time,and oxygen desaturation index were higher(t=5.969,5.829,2.887,3.003,5.937).The Oxy-Hb concentration at T0,T1,and T2 in the MCI group was lower(t=14.940,11.280,5.721),and the peak time was higher(t=18.800,13.350,9.827).In MCI patients,the concentration of Oxy-Hb during T0 was negatively correlated with the scores of Pittsburgh sleep quality index,sleep time,total sleep time,and sleep efficiency(r=-0.611,-0.388,-0.563,-0.356).It was positively correlated with sleep efficiency and total sleep time(r=0.754,0.650),and negatively correlated with oxygen desaturation index(r=-0.561)and FSS score(r=-0.526).All comparisons were P<*** Patients with MCI and sleep disorders have lower near-infrared brain function than norm

关键词： Mild Cognitive impairment Sleep disorders Near-infrared Brain functional Characteristics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Design,Synthesis and Pharmacological Evaluation of Novel 4-Phenoxyquinoline Derivatives as VEGFR2 Kinase Inhibitors for Tumor Treatment

引用

Chemical Research in Chinese Universities 2025年第1期41卷 66-78页

作者： JIANG Wei CHEN Jiayan wang Haifeng XUE Aiqi ZHANG xinyang GUAN Jichi WEI Lulu CAI Jianfeng HU yong LIU Dan College of Chemical Engineering Shenyang University of Chemical TechnologyShenyang110142P.R.China Institute of Materials Engineering College of Engineering and Applied SciencesNanjing UniversityNanjing210093P.R.China Department of Chemistry University of South Florida4202 E.Fowler AveTampaFL33620USA

Vascular endothelial growth factor 2(VEGFR2)plays a vital role in regulating of tumor metastasis and angiogenesis,which has emerged as one of the effective targets for clinical tumor ***,a series of novel facilely accessible 4-phenoxyquinoline derivatives was prepared and assessed for their antitumor activity against three human tumor cell lines(SGC-7901,HepG2 and A549).Among these compounds,6a,6b and 6c show strong antitumor activity on HepG2 cells[the drug concentration of eliminating half of tumor cells(IC_(50))=9.33,1.84,8.54μmol/L].Notably,compound 6b shows potent selective inhibitory activity against VEGFR2 kinase with an IC_(50) value of 4.66 nmol/*** excellent anti-angiogenesis capability of compound 6b was confirmed by tube formation and chick chorioallantoic membrane(CAM)*** vivo studies confirmed that compound 6b was able to inhibit tumor growth in HepG2 xenografts of BALB/c nude mice without obvious side or toxic *** results demonstrated that compound 6b exhibited remarkable anti-angiogenesis and tumor growth inhibitory effects with less toxicity in vitro and in vivo *** findings highlighted the potential of compound 6b as a promising VEGFR2 kinase inhibitor for the development of antitumor drugs.

关键词： ar endothelial growth factor 2(VEGFR2) 4-Phenoxyquinoline Inhibitor Anti-tumor Angiogenesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：