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Transcutaneous electrical acupoint stimulation benefits postoperative pain relief of oocyte retrieval:A randomized controlled trial

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Journal of Integrative Medicine 2024年第1期22卷 32-38页

作者： Li-ying Liu Yang Su Rong-rong Wang Yuan-yuan Lai Lei Huang Yi-ting Li Xin-yue Tao Meng-hua Su Xiao-yan Zheng Shi-chen Huang yong-na wu Si-yi Yu Fan-rong Liang Jie Yang Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu 610000Sichuan ProvinceChina Traditional Chinese Medicine Department Sichuan Jinxin Xi’nan Women's and Children's HospitalChengdu 610000Sichuan ProvinceChina

Background Transvaginal oocyte retrieval is frequently followed by adverse events related to anesthesia and the *** research showed that transcutaneous electrical acupoint stimulation(TEAS)can relieve intraoperative pain and postoperative *** This study examined whether TEAS can alleviate pain and relieve adverse symptoms after oocyte ***,setting,participants and interventions Altogether 128 patients were randomly divided into the TEAS group and the mock TEAS *** two groups received a 30-minute-long TEAS or mock TEAS treatment that began 30 min after oocyte *** outcome measures The primary outcome was the visual analog scale(VAS)pain *** outcomes were pressure pain threshold,McGill score,pain rating index(PRI),present pain intensity(PPI),VAS stress score,VAS anxiety score,and postoperative adverse *** The baseline characteristics of the two groups were comparable(P>0.05).The VAS pain scores of the TEAS group were lower than those of the mock TEAS group at 60 and 90 min after oocyte retrieval(P0.05).The TEAS group was superior to the mock TEAS group for relieving postoperative adverse symptoms(P<0.05).Conclusion TEAS treatment can relieve postoperative pain and postoperative adverse symptoms for patients undergoing oocyte retrieval.

关键词： Transcutaneous electrical acupoint stimulation Fertilization Embryo transfer Oocyte retrieval Pain Randomized controlled trial

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Synthesis of Long-Chain Oligomeric Donor and Acceptors via Direct Arylation for Organic Solar Cells

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Chinese Journal of Chemistry 2024年第5期42卷 523-532页

作者： Yu wu Xin-Yu He Xu-Min Huang Ling-Jun Yang Peng Liu na Chen Chang-Zhi Li Shi-yong Liu Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry College of MaterialsMetallurgical and ChemistryJiangxi University of Science and TechnologyGanzhouJiangxi341000 China Department of Polymer Science and Engineering Zhejiang UniversityHangzhouZhejiang310027 China

The rapid synthesis of structurally complicated electron donors&acceptors still remains a major challenge in organic solar cells(OSC).In this work,we developed a highly efficient strategy to access long-chain oligomeric donor and acceptors for OSC applications.A series of cyclopentadithiophene(CPDT)and benzothiadiazole(BT)-basedπ-conjugated oligomers,i.e.,three oligomeric acceptors(BTDT)n-IC(n=1—3)and one long-chain oligomeric donor(BTDT)4-RD,are facilely synthesized by an atom-and step-economical,and labor-saving direct C—H arylation(DACH)reaction(i.e.,C—H/C—Br cross coupling).Note that(BTDT)4-RD involving five CPDT,four BT and two rhodamine(RD)building blocks is the longest oligomeric donor in the fullerene-free OSC devices ever *** dependence of the structure-property-performance correlation of(BTDT)n-IC(n=1—3)and(BTDT)4-RD on theπ-conjugation lengths is thoroughly investigated by opto-electrochemical measurements,bulk heterojunction(BHJ)OSC devices and ***(BTDT)1-IC:PBDB-T and(BTDT)4-RD:Y6 BHJs achieve power conversion efficiencies of 9.14%and 4.51%,*** findings demonstrate that DACH reaction is a powerful tool to tune the opto-electronic properties and device performances by regulating the lengths ofπ-conjugated oligomers with varied numbers of repeating units.

关键词： Long-chainπ-conjugated oligomer Organic solar cells Direct arylation Atom-economical synthesis Cyclopentadithiophene Benzothiadiazole C—H activation Conjugation Oligomers

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Random Raman Fiber Laser as a Liquid Refractive Index Sensor

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Photonic Sensors 2024年第1期14卷 13-22页

作者： Bing HAN Yuxi MA Han wu yong ZHAO College of Information Science and Engineering Northeastern UniversityShenyang 110819China Hebei Key Laboratory of Micro-nano Precision Optical Sensing and Measurement Technology Qinhuangdao 066004China College of Electronics and Information Engineering Sichuan UniversityChengdu 610064China

In this paper,a new concept of forward-pumped random Raman fiber laser(RRFL)-based liquid refractive index sensing is proposed for the first *** liquid refractive index sensing,the flat fiber end immersed in the liquid can act as the point reflector for generating random fiber lasing and also as the sensing *** to the high sensitivity of the output power of the RRFL to the reflectivity provided by the point reflector in the ultralow reflectivity regime,the proposed RRFL is capable of achieving liquid refractive index sensing by measuring the random lasing output *** theoretically investigate the effects of the operating pump power and fiber length on the refractive index sensitivity for the proposed *** a proof-of-concept demonstration,we experimentally realize high-sensitivity half-open short-cavity RRFL-based liquid refractive index sensing with the maximum sensitivity and the sensing resolution of-39.88W/RIU and 2.5075×10^(-5) RIU,*** also experimentally verify that the refractive index sensitivity can be enhanced with the shorter fiber length of the *** work extends the application of the random fiber laser as a new platform for highly-sensitive refractive index sensing in chemical,biomedical,and environmental monitoring applications,etc.

关键词： Fiber optic sensors refractive index measurements fiber lasers Rayleigh scattering stimulated Raman scattering

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Experimental and Numerical Investigation of Non-synchronous Blade Vibration Excitation in a Transonic Axial Compressor

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Journal of Thermal Science 2024年第2期33卷 602-610页

作者： WANG Songbai wu Yadong CHEN yong CAO Zhipeng School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai200240China AECC Sichuan Gas Turbine Establishment Chengdu610500China

The complex flow phenomenon of rotating instability(RI) and its induced non-synchronous vibration(NSV) have become a significant challenge as they continuously increase aerodynamic *** study aims to provide an understanding of the non-synchronous blade vibration phenomenon caused by the rotating instability of a transonic axial compressor *** this case,blade vibrations and non-synchronous excitation are captured by strain gauges and unsteady wall pressure transducer *** numerical simulations for a full-annulus configuration are used to obtain the non-synchronous flow *** results show that the first-stage rotor blade exhibits an NSV close to the first bending mode;NSV is accompanied by a sharp increase in pressure pulsation;amplitude can reach 20%,and unsteady aerodynamic frequency will lock in a structural mode frequency when the blade vibrates in a large-amplitude *** predicted NSV frequency aligns well with the experimental *** dominant mode of circumferential instability flow structure is approximately 47% of the number blades,and the cell size occupies 2-3 pitches in the circumferential *** full-annulus unsteady simulations demonstrate that the streamwise oscillation of the shedding and reattachment vortex structure is the main cause of NSV owing to the strong interaction between the tip leakage and separation vortices near the suction surface.

关键词： non-synchronous vibration transonic axial compressor rotor blade rotating instabilities unsteady flow

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Modeling analysis of cobalt-based Fischer-Tropsch catalyst particles

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Chinese Journal of Chemical Engineering 2024年第6期70卷 82-92页

作者： Huashuai wu Gang Wang yong Yang yongwang Li College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China national Energy Research&Development Center for Coal to Liquid Fuels Synfuels China CompanyLimitedBeijing 101400China

The influences of particle size,shape,and catalyst distribution on the reactivity and hydrocarbon product selectivity of a cobalt-based catalyst for Fischer-Tropsch synthesis were investigated in the present work.A self-consistent kinetic model for Fischer-Tropsch reaction proposed here was found to correlate experimental data well and hence was used to describe the consumption rates of reactants and formation rates of hydrocarbon *** perturbed-chain statistical associating fluid theory equation of state was used to describe vapor-liquid equilibrium behavior associated with Fischer-Tropsch *** interaction between intraparticle diffusion and Fischer-Tropsch reaction was investigated in *** showed that in order to avoid the adverse influence of intraparticle diffusional limitations on catalyst reactivity and product selectivity,the use of small particles is *** eggshell spherical particles are shown to keep the original catalyst reactivity and enhance the selectivity of heavy hydrocarbon *** suitable layer thickness for a spherical particle with a diameter of 2 mm is nearly 0.15 *** the same outer diameter of 2 mm,the catalyst reactivity and heavy product selectivity of hollow cylindrical particles with a layer thickness of 0.25 mm are found to be larger than eggshell spherical *** the viewpoint of catalytic performance,hollow cylindrical particles are a better choice for industrial applications.

关键词： Fischer-Tropsch synthesis Kinetic modeling Vapor-liquid equilibria Numerical simulation Intraparticle diffusion Particle shapes

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Construction of CDKN2A-related competitive endogenous Rna network and identification of GAS5 as a prognostic indicator for hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1514-1531页

作者： yong Pan Yi-Ru Zhang Ling-Yun Wang Li-na wu Ying-Qiu Ma Zhou Fang Shi-Bo Li Department of Infectious Disease Zhoushan HospitalWenzhou Medical UniversityZhoushan 316021Zhejiang ProvinceChina State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital of Zhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Department of Infectious Disease The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina

BACKGROUND Competitive endogenous Rna(ceRna)is an innovative way of gene expression modulation,which plays a crucial part in ***,the intricacy and behavioral characteristics of the ceRna network in hepatocellular carcinoma(HCC)remain *** To establish a cyclin dependent kinase inhibitor 2A(CDKN2A)-related ceRna network and recognize potential prognostic indicators for *** The mutation landscape of CDKN2A in HCC was first explored using the cBioPortal *** expression analysis was implemented between CDKN2Ahigh and CDKN2Alow expression HCC *** targeted microRnas were predicted by lncBasev3.0,and the targeted mRnas were predicted by miRDB,and Targetscan *** univariate and multivariate analysis were utilized to identify independent prognostic *** CDKN2A was frequently mutated and deleted in *** single-cell Rna-sequencing analysis revealed that CDKN2A participated in cell cycle *** CDKN2A-related ceRna network-growth arrest specific 5(GAS5)/miR-25-3p/SRY-box transcription factor 11(SOX11)was successfully ***5 was recognized as an independent prognostic biomarker,whose overexpression was correlated with a poor prognosis in HCC *** association between GAS5 expression and methylation,immune infilt-ration was ***,traditional Chinese medicine effective components targeting GAS5 were *** This CDKN2A-related ceRna network provides innovative insights into the molecular mechanism of HCC formation and ***,GAS5 might be a significant prognostic biomarker and therapeutic target in HCC.

关键词： Hepatocellular carcinoma Competitive endogenous Rna Molecular mechanism Prognosis Biomarker

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On the Probability of Generating a Primitive Matrix

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Journal of Systems Science & Complexity 2024年第4期37卷 1755-1771页

作者： CHEN Jingwei FENG yong LIU Yang wu Wenyuan Chongqing Key Laboratory of Automated Reasoning and Cognition Chongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China Chongqing College University of Chinese Academy of SciencesChongqing 400714China Key Laboratory of Advanced Manufacturing Technology of Ministry of Education Guizhou UniversityyGuiyang 550025China Information Science and Engineering Chongqing Jiaotong UniversityChongqing 400074China

Given a k×n integer primitive matrix A(i.e.,a matrix can be extended to an n×n unimodular matrix over the integers)with the maximal absolute value of entries‖A‖bounded by an integer λ from above,the authors study the probability that the m×n matrix extended from A by appending other m-k row vectors of dimension n with entries chosen randomly and independently from the uniform distribution over{0,1,…,λ-1}is still *** authors present a complete and rigorous proof of a lower bound on the probability,which is at least a constant for fixed m in the range[k+1,n-4].As an application,the authors prove that there exists a fast Las Vegas algorithm that completes a k×n primitive matrix A to an n×n unimodular matrix within expected O(n^(ω)log‖A‖)bit operations,where O is big-O but without log factors,ω is the exponent on the arithmetic operations of matrix multiplication.

关键词： Integer matrix matrix completion probabilistic algorithm unimodular matrix

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Boosted sustained-release with iron-based MOF-derived mesoporouscarbon-spheres as a nitroimidazole drugs carrier

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Particuology 2024年第3期86卷 269-280页

作者： Danping wu Jiaying Zou Junyi Chen Yan Li na Ma Wei Dai College of Chemistry and Materials Science Zhejiang Normal UniversityJinhua321004China College of Life Sciences Zhejiang Normal UniversityJinhua321004China College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua321004China

Metal-organic framework(MoF)with a buildable internal structure has aroused great interest focus as self-sacrificing precursors of porous carbon(PC).However,as a drug carrier,the MOF-derived PC developed thus far are generally composed of irregular powder shape due to their crystalline nature,which consequently causing the cerebral infarction,cerebral thrombosis,and other blood *** this article,we propose a novel approach to constructing amorphous carbon microspheres(AcMs)by dis-torting the topological network through hydrothermal treatment precursors of MIL-101(Fe).Then,a distinctive MIL-101(Fe)-derived spherical porous carbons(MSPC)is achieved through high temperature calcination toward *** of the glucose initial concentration and hydrothermal treatment time on the sphericity of the as-prepared mesoporous MsPC were investigated in *** the loading capacities and sustained-release performances of nitroimidazole drugs over MsPC through simulation internal environment of human body at different pH values was systematically *** nitro-imidazole drugs loading rate and release time of MsPC are 10% and 17 h under preferred ***,the MSPC exhibited very low toxicity on Hela cells and 293T cells at the concentrations tested(10-800μg mL^(-1)).This study,therefore,supports the potential of the mesoporous carbon spheres as a carrierfor nitroimidazole drug delivery.

关键词： Ornidazole Metronidazole Carbon spheres Sustained-release performance Biocompatibility

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Machine learning-assisted efficient design of Cu-based shape memory alloy with specific phase transition temperature

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 773-785页

作者： Mengwei wu Wei yong Cunqin Fu Chunmei Ma Ruiping Liu Department of Materials Science and Engineering China University of Mining&Technology(Beijing)Beijing 100083China Institute for Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China

The martensitic transformation temperature is the basis for the application of shape memory alloys(SMAs),and the ability to quickly and accurately predict the transformation temperature of SMAs has very important practical *** this work,machine learning(ML)methods were utilized to accelerate the search for shape memory alloys with targeted properties(phase transition temperature).A group of component data was selected to design shape memory alloys using reverse design method from numerous unexplored *** modeling and feature modeling were used to predict the phase transition temperature of the shape memory *** experimental results of the shape memory alloys were obtained to verify the effectiveness of the support vector regression(SVR)*** results show that the machine learning model can obtain target materials more efficiently and pertinently,and realize the accurate and rapid design of shape memory alloys with specific target phase transition *** this basis,the relationship between phase transition temperature and material descriptors is analyzed,and it is proved that the key factors affecting the phase transition temperature of shape memory alloys are based on the strength of the bond energy between *** work provides new ideas for the controllable design and performance optimization of Cu-based shape memory alloys.

关键词： machine learning support vector regression shape memory alloys martensitic transformation temperature

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Carbon-based interface engineering and architecture design for high-performance lithium metal anodes

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Carbon Energy 2024年第1期6卷 207-235页

作者： na Zhu Yuxiang Yang Yu Li Ying Bai Junfeng Rong Chuan wu SINOPEC Research Institute of Petroleum Processing Co. Ltd.BeijingChina Beijing Key Laboratory of Environmental Science and Engineering School of Materials Science and EngineeringBeijing Institute of TechnologyBeijingChina Yangtze Delta Region Academy of Beijing Institute of Technology JiaxingChina

Metallic lithium(Li)is considered the“Holy Grail”anode material for the nextgeneration of Li batteries with high energy density owing to the extraordinary theoretical specific capacity and the lowest negative electrochemical ***,owing to inhomogeneous Li-ion flux,Li anodes undergo uncontrollable Li deposition,leading to limited power output and practical *** materials and their composites with controllable structures and properties have received extensive attention to guide the homogeneous growth of Li to achieve high-performance Li *** this review,the correlation between the behavior of Li anode and the properties of carbon materials is ***,we review emerging strategies for rationally designing high-performance Li anodes with carbon materials,including interface engineering(stabilizing solid electrolyte interphase layer and other functionalized interfacial layer)and architecture design of host carbon(constructing three-dimension structure,preparing hollow structure,introducing lithiophilic sites,optimizing geometric effects,and compositing with Li).Based on the insights,some prospects on critical challenges and possible future research directions in this field are *** is anticipated that further innovative works on the fundamental chemistry and theoretical research of Li anodes are needed.

关键词： carbon materials dendrites hosts interfacial layers Li metal anodes

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