检索结果-南通市图书馆

Triaxial mechanical properties and precursors of instability damage in rocks with different laminar dip angles

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第2期21卷 648-661页

作者： SUN Xiaoming shi Fukun DING Jiaxu TAO Zhigang HE Linsen YANG Liu ZHANG yong MIAO Chengyu Inner Mongolia Research Institute China University of Mining and Technology(Beijing)Beijing 100083China State Key Laboratory for Tunnel Engineering China University of Mining and Technology(Beijing)Beijing 100083China

To investigate the mechanical failure characteristics of volcanic breccia with different bedding dip angles in deep layers,triaxial compression experiments were conducted on specimens taken from volcanic rock layers in the Junggar Basin,*** changing the confining pressure,we compared the mechanical properties,acoustic emission characteristics,and fractal features of the acoustic emission sequence for volcanic breccia with different bedding dip *** research results indicate that as the bedding dip angle increases,peak strength,internal friction angle,and cohesion exhibit a“U-shaped”variation *** correlation dimension of the acoustic emission amplitude was calculated using the G-P algorithm,revealing that volcanic breccia exhibits fractal ***,a positive correlation between the correlation dimension and the bedding dip angle was *** the stress of the test specimen reaches 0.8σ_(c),there is a significant decrease in the fractal dimension,serving as a criterion for predicting the failure of the *** analyzing the changes in fractal dimension at different stress levels,the slope of the fractal dimension△D<-0.5 can be used as a precursor to failure for test specimens with a bedding dip angle of 15°≤β≤45°.Similarly,when the bedding dip angle of the specimen is 0°≤β<15°or 45°<β≤90°,△D<0 can be considered as a precursor to specimen *** study provides theoretical references for understanding the failure patterns of volcanic rock.

关键词： Volcanic breccia Bedding dip Acoustic emission Fractal dimension Harbinger of destruction

Petrogenesis and Economic Potential of the Sangong MaficUltramafic Intrusion in the Eastern Tianshan, Central Asian Orogenic Belt: Constraints from Mineral, Whole-Rock, and PGE Geochemistry

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第3期35卷 850-865页

作者： Guochao Zhou Yuwang Wang jingbin Wang Yu shi Hongjing Xie Dedong Li yong Fu Pan Wu College of Resources and Environmental Engineering Guizhou UniversityGuiyang 550012China Technic Research Center for Deep Resources Exploration in Non-ferrous Metal Mines Beijing Institute of Geology for Mineral Resources Co.Ltd.Beijing 100012China Sino-Zijin Resources Ltd. Beijing 100012China State Key Laboratory of Nuclear and Environment East China University of TechnologyNanchang 330013China

The Sangong Cu-Ni sulfide mineralized mafic-ultramafic intrusion is located on the southern margin of the Bogeda-Harlik belt,eastern Tianshan,*** intrusion is a well-differentiated complex and is comprised of leucogabbro,gabbro,olivine gabbro,Pl-bearing peridotite,and Pl-bearing *** Pl-bearing pyroxenite hosts both irregularly disseminated sulfide and round droplet *** intrusive rocks have a wide range of SiO_(2)(42.1 wt.%-50.48 wt.%)and MgO(6.21 wt.%-22.11 wt.%),and are enriched in light rare earth elements(LREE),large-ion lithophile elements(LILE;e.g.,Rb,Ba,Sr,and Pb),and palladium platinum group elements(PPGE)but depleted in high-field-strength elements(HFSE;e.g.,Nb,Ta,and Ti)and iridium PGEs(IPGE).These geochemical characteristics indicate that the Sangong mafic-ultramafic intrusion was derived from high degree of partial melting of depleted mantle and interacted with subduction-related *** low Pd/Ir(3.21-27.44)but high Ni/Cu(1.64-24.16)ratios,combined with the olivine crystals with low Fo(60.88-78.65)and Ni(54.99 ppm-1688.87 ppm)concentrations suggest that the parental magma of the Sangong intrusion were likely high MgO basaltic in composition that experienced extensive evolution prior *** Ce/Pb ratios(5.8-13.6)and Nb/U ratios(11.6-30.3)of the intrusive rocks all range between MORB and crustal values,the Nb/Yb and Th/Yb values are close to the lower crust values,together with the low Se/S ratios[(17-100)×10^(-6))]suggest that the magma experienced assimilation not only in mantle source but also in conduit,but the degree of crustal contamination is *** Cu/Pd ratios of the rocks range from 3.9×10^(4) to 10.8×10^(4),and the Cu/Zr ratios of Pl-bearing pyroxenite in the Sangong intrusion are>1,combined with the presence of sulfide droplets in the Pl-bearing pyroxenite,indicating the parental magma experienced sulfide saturation and the economical ore bodies may present in the depth of the ***,gi

关键词： Sangong mafic-ultramafic intrusion deposits geochemistry PGE economic potential eastern Tianshan.

Recent development of aspiration pump in the aspiration thrombectomy system

在线全文

学校读者我要写书评

暂无评论

Medicine in Novel Technology and Devices 2024年第2期22卷 1-8页

作者： Chen Wei jing Dong Hongyi Yang jinghong shi Huihui Fang Yangjie Zuo Yubing shi The Second Clinical College of Medicine Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina Department of Cardiology the Second Affiliated Hospital of Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina Institute of Integrative Medicine Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina School of Medical Technology Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina School of Engineering Staffordshire UniversityStoke-on-TrentStaffordshireUK

Vascular embolic diseases are associated with blockage of blood supply to vital organs and thus are *** thrombectomy is becoming the primary choice for revascularization in the treatment of vascular occlusions *** the power source in the aspiration thrombectomy procedure,the aspiration pump directly influences the outcome of the *** research surveyed the current technical developments of the aspiration pump in China through reviewing information obtained from the patent database and technical literatures,commented on the issues in the current patent designs,and gave suggestions for future design *** study can be used as a reference for researchers and developers of medical devices besides the neurosurgeons.

关键词： Aspiration pump Thrombus Thrombectomy Vascular embolic diseases Aspiration thrombectomy

Human Recombinant B7-H3 Expressed in *** Enhances T Lymphocyte Proliferation and IL-10 Secretion in Vitro

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Biochimica et Biophysica Sinica 2004年第6期 430-436页

作者： Guang-Bo ZHANG,yong-jing CHEN,Qin shi,Hong-Bing MA,Yan GE,Qin WANG,Zhi JIANG,Ying XU,and Xue -Guang ZHANGInstitute of Biotechnology Soochow University Key Laboratory of Clinical Immunology of Jiangsu Province Suxhou 215007,China

o explore the biofunctions of human B7-H3 on activated T lymphocyte, the gene of humanB7-H3 encoding the extracellular region (IgV-like and IgC-like domains) was obtained by RT-PCR from human lung cells and subcloned into the prokaryotic expression vector pGEX-5X-3 to express glutathioneS-transferase (GST) fusion protein, A 49 kD fusion protein (named as GST/hB7-H3 hereafter) was induced by IPTG and purified by standard methods reported in prokaryotic system. In the presence of the first signal imitated by anti-CD3 monoclonal antibody, T lymphocyte proliferation was observed by incubating purified T cells with soluble GST/hB7-H3 fusion protein by MTT assay. The concentrations of JFN-y and LL-10 in the supernatants of T cells were determined by ELISA. The results showed that the GST/hB7-H3 protein produced in bacteria had. modest biological activities to proliferate the T lymphocyte and enhance IFN-y as well as IL-10 secretion.

关键词： B7-H3 GST-fusion protein T lymphocyte proliferation.

Artificial intelligence enhances the management of esophageal squamous cell carcinoma in the precision oncology era

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第39期30卷 4267-4280页

作者： Wan-Yue Zhang yong-Jian Chang Rui-Hua shi School of Medicine Southeast UniversityNanjing 221000Jiangsu ProvinceChina School of Cyber Science and Engineering Southeast UniversityNanjing 210009Jiangsu ProvinceChina Department of Gastroenterology Zhongda HospitalSoutheast UniversityNanjing 210009Jiangsu ProvinceChina

Esophageal squamous cell carcinoma(ESCC)is the most common histological type of esophageal cancer with a poor *** diagnosis and prognosis assessment are crucial for improving the survival rate of ESCC *** the advancement of artificial intelligence(AI)technology and the proliferation of medical digital information,AI has demonstrated promising sensitivity and accuracy in assisting precise detection,treatment decision-making,and prognosis assessment of *** has become a unique opportunity to enhance comprehen-sive clinical management of ESCC in the era of precision *** review examines how AI is applied to the diagnosis,treatment,and prognosis assessment of ESCC in the era of precision oncology,and analyzes the challenges and potential opportunities that AI faces in clinical *** insights into future prospects,it is hoped that this review will contribute to the real-world application of AI in future clinical settings,ultimately alleviating the disease burden caused by ESCC.

关键词： Esophageal squamous cell carcinoma Artificial intelligence Deep learning Machine learning Precision tumor therapy

Dynamic interwell connectivity analysis of multi-layer waterflooding reservoirs based on an improved graph neural network

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2024年第2期21卷 1062-1080页

作者： Zhao-Qin Huang Zhao-Xu Wang Hui-Fang Hu shi-Ming Zhang yong-Xing Liang Qi Guo Jun Yao School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Exploration and Development Research Institute Shengli OilfieldSINOPECDongying257015ShandongChina

The analysis of interwell connectivity plays an important role in the formulation of oilfield development plans and the description of residual oil distribution. In fact, sandstone reservoirs in China's onshore oilfields generally have the characteristics of thin and many layers, so multi-layer joint production is usually adopted. It remains a challenge to ensure the accuracy of splitting and dynamic connectivity in each layer of the injection-production wells with limited field data. The three-dimensional well pattern of multi-layer reservoir and the relationship between injection-production wells can be equivalent to a directional heterogeneous graph. In this paper, an improved graph neural network is proposed to construct an interacting process mimics the real interwell flow regularity. In detail, this method is used to split injection and production rates by combining permeability, porosity and effective thickness, and to invert the dynamic connectivity in each layer of the injection-production wells by attention *** on the material balance and physical information, the overall connectivity from the injection wells,through the water injection layers to the production layers and the output of final production wells is established. Meanwhile, the change of well pattern caused by perforation, plugging and switching of wells at different times is achieved by updated graph structure in spatial and temporal ways. The effectiveness of the method is verified by a combination of reservoir numerical simulation examples and field example. The method corresponds to the actual situation of the reservoir, has wide adaptability and low cost, has good practical value, and provides a reference for adjusting the injection-production relationship of the reservoir and the development of the remaining oil.

关键词： Graph neural network Dynamic interwell connectivity Production-injection splitting Attention mechanism Multi-layer reservoir

Effect of plateletcrit and methylenetetrahydrofolate reductase(MTHFR)C677T genotypes on folic acid efficacy in stroke prevention

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第6期9卷 2694-2701页

作者： Yuncong shi Zhengzhipeng Zhang Binyan Wang Yu Wang Xiangyi Kong yong Sun Aimin Li Yimin Cui Yan Zhang Jianping Li yong Huo Hui Huang Cardiovascular Department The Eighth Affiliated HospitalJoint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic DiseasesSun Yat-sen UniversityShenzhenChina Shenzhen Evergreen Medical Institute ShenzhenChina Shenzhen Tailored Medical Laboratory ShenzhenChina Department of Cardiology Beijing Anzhen HospitalCapital Medical UniversityBeijingChina Department of Neurosurgery The First Affiliated Hospital of Kangda College of Nanjing Medical UniversityLianyungangChina Institute of Clinical Pharmacology Peking University First HospitalBeijingChina Department of Cardiology Peking University First HospitalBeijingChina

Previous studies have shown that low platelet count combined with high plasma total homocysteine(tHcy)increased stroke risk and can be lowered by 73% with folic ***,the combined role of other platelet activation parameters and the methylenetetrahydrofolate reductase(MTHFR)C677T genotypes on stroke risk and folic acid treatment benefit remain to be *** study aimed to investigate if platelet activation parameters and MTHFR genotypes jointly impact folic acid treatment efficacy in first stroke *** were derived from the China Stroke Primary Prevention *** study includes a total of 11,185 adult hypertensive patients with relevant platelet activation parameters and MTHFR genotype *** simultaneously considering both platelet activation parameters(plateletcrit,platelet count,mean platelet volume,platelet distribution width)and MTHFR genotypes,patients with both low plateletcrit(Q1)and the TT genotype had the highest stroke incidence rate(5.6%)in the enalapril *** subgroup significantly benefited from folic acid treatment,with a 66% reduction in first stroke(HR:0.34;95%CI:0.14-0.82;p=0.016).Consistently,the subgroup with low plateletcrit(Q1)and the CC/CT genotype also benefited from folic acid treatment(HR:0.40;95%CI:0.23-0.70;p=0.001).In Chinese hypertensive adults,low plateletcrit can identify those who may greatly benefit from folic acid treatment,in particular,those with the TT genotype,a subpopulation known to have the highest stroke risk.

关键词： prevention treatment MTHFR

Designing high piezoelectric properties at the BaTiO_(3)–PbZrO_(3)–PbTiO_(3)phase boundary by Landau–Devonshire theory

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Dielectrics 2024年第2期14卷 33-41页

作者： Yu Song Xiaoming shi Dan Li jing Wang Houbing Huang School of Materials Science and Engineering Beijing Institute of Technology Beijing 100081P.R.China Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing 100081P.R.China School of Electronic Information and Electrical Engineering Chengdu University Chengdu 610100P.R.China

Ferroelectric materials possessing exceptional piezoelectric attributes have garnered widespread utilization in various *** solution systems improve piezoelectric properties through multiphase mixing,but the methodologies for effective design remain *** on the Landau–Devonshire theory,we propose a theoretical design *** materials with morphotropic phase boundary(MPB)compositions are added with new elements to increase the free energy of the original stabilized phase and lower the energy barrier(EB).Flatter EBsand higher piezoelectric coefficients are found at the phase boundaries of the ternary *** calculating the phase diagram,piezoelectric coefficient,dielectric constant,polarization,and EBs,we reveal the origin of the highest piezoelectric coefficient at the phase *** study underscores the importance of the EBs for polarization rotation in characterizing piezoelectric properties and proposes a theoretical design method for exploring materials with high piezoelectric coefficients.

关键词： BaTiO_(3)-PbZrO_(3)-PbTiO_(3) piezoelectric properties free energy barrier thermodynamic calculation Landau-Devonshire theory

Bioinspired Stretchable MXene Deformation-Insensitive Hydrogel Temperature Sensors for Plant and Skin Electronics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 389-401页

作者： Jun Wu Yinghui Li Shengshun Duan Zhehan Wang Xu jing Yucheng Lin Di Zhu Wei Lei Qiongfeng shi Li Tao Joint International Research Laboratory of Information Display and Visualization School of Electronic Science and EngineeringSoutheast UniversityNanjingJiangsu 210096China School of Materials Science and Engineering Southeast UniversityNanjingJiangsu 210096China Center of 2D Materials and Devices Southeast UniversityNanjingJiangsu 210096China

Temperature sensing is of high value in the wearable healthcare,robotics/prosthesis,and noncontact physiological ***,the common mechanic deformation,including pressing,bending,and stretching,usually causes undesirable feature size changes to the inner conductive network distribution of temperature sensors,which seriously influences the ***,inspired by the transient receptor potential mechanism of biological thermoreceptors that could work precisely under various skin contortions,we propose an MXene/Clay/poly(N-isopropylacrylamide)(PNIPAM)(MCP)hydrogel with high stretchability,spike response,and deformation *** dynamic spike response is triggered by the inner conductive network transformation from the 3-dimensional structure to the 2-dimensional surface after water being discharged at the threshold *** water discharge is solely determined by the thermosensitivity of PNIPAM,which is free from mechanical deformation,so the MCP hydrogels can perform precise threshold temperature(32℃)sensing under various deformation conditions,i.e.,pressing and 15%*** a proof of concept,we demonstrated the applications in plant electronics for the real-time surface temperature monitoring and skin electronics for communicating between human and *** research opens venues for the accurate temperature-threshold sensation on the complicated surface and mechanical conditions.

关键词： stretching proof precise