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Transjugular intrahepatic portosystemic shunt for esophagogastric variceal bleeding in patients with hepatocellular carcinoma and portal vein tumor thrombus

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2778-2786页

作者： Zhi-Qiang Wu Fan Wang Feng-Pin Wang Hong-Jie Cai Song Chen jian-yong yang Wen-Bo Guo Department of Interventional Radiology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina Department of Medical Oncology Affiliated Cancer Hospital&Institute of Guangzhou Medical UniversityGuangzhou 510080Guangdong ProvinceChina

BACKGROUND Whether hepatocellular carcinoma(HCC)with portal vein tumor thrombus(PVTT)and acute esophagogastric variceal bleeding(EGVB)can improve the success rate of endoscopic hemostasis and overall survival(OS)from transjugular intrahepatic portosystemic shunt(TIPS)remains *** To compare the clinical outcomes between TIPS and standard treatment for such HCC *** This monocenter,retrospective cohort study included patients diagnosed as HCC with PVTT and upper gastrointestinal *** were grouped by the treatment(TIPS or standard conservative treatment).The success rate of en-doscopic hemostasis,OS,rebleeding rates,and main causes of death were *** Between July 2015 and September 2021,a total of 77 patients(29 with TIPS and 48 with standard treatment)were *** success rate of endoscopic hemostasis was 96.6%in the TIPS group and 95.8%in the standard treatment *** the 29 patients in TIPS group successful underwent TIPS procedure and had a better OS compared with standard treatment within the first 160 days after treatment(68 days vs 43 days,P=0.022),but shorter OS after 160 days(298 days vs 472 days, P = 0.022). Cheng’s Classification of PVTT, total bilirubin and Child-Pugh class wereindependently negative associated with OS (all P < 0.05). The main causes of death were liver failure or hepaticencephalopathy (75.9%) in the TIPS group and rebleeding (68.8%) in the standard *** could reduce the risk of early death due to rebleeding and prolong short-term survival in HCC patients withPVTT and acute EGVB, which deserves further investigation.

关键词： Hepatocellular carcinoma Portal vein tumor thrombus Transjugular intrahepatic portosystemic shunts Acute esophagogastric variceal bleeding Standard treatment Endoscopic treatment

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Novel Global Optimization Algorithm with a Space-Filling Curve and Integral Function

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Journal of the Operations Research Society of China 2021年第3期9卷 619-640页

作者： Zhong-Yu Wang yong-jian yang Department of Mathematics Shanghai UniversityShanghai 200444China

In this study,we consider the global optimization problem in a *** use a class of series to construct a curve in a hypercube,which can fill the hypercube,and we present an integral function on the *** on the integral function,we propose an algorithm for solving the global optimization ***,we perform a convergence analysis and numerical experiments to demonstrate the effectiveness of the proposed algorithm.

关键词： Global optimization algorithm Integral function Space-filling curve Filled function

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Room temperature nonlinear mass sensing based on a hybrid spin-nanoresonator system

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Chinese Physics B 2020年第10期29卷 501-506页

作者： jian-yong yang Hua-Jun Chen School of Mechanics and Photoelectric Physics Anhui University of Science and TechnologyHuainan 232001China

We present a room temperature nonlinear mass sensing based on a hybrid spin-nanoresonator system with the microwave pump–probe technique and the spin readout technique, which includes a single spin of nitrogen–vacancy (NV) center in diamond and a nanomechanical cantilever. The resonance frequency of the nanoresonator can be measured with the nolinear Kerr spectrum, and the parameters that influence the nolinear Kerr spectrum are also investigated. Further, according to the relationship between frequency shifts and variable mass attached on the nanoresonator, this system can also be used to detect the mass of DNA molecules with the nolinear Kerr spectrum. Benefiting from the single spin of the NV center in diamond has a long coherence time at 300 K, the hybrid system can realize room temperature mass sensor, and the mass response rate can reach 2600 zg/Hz.

关键词： nonlinear mass sensing nitrogen-vacancy center nanomechanical resonator

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Unification of Filled Function and Tunnelling Function in Global Optimization

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Acta Mathematicae Applicatae Sinica 2007年第1期23卷 59-66页

作者： Wei Wang yong-jian yang Lian-sheng Zhang Department of Mathematics East China University of Science and Technology Shanghai 200237 China Department of Mathematics Shanghai University Shanghai 200444 China

In this paper, two auxiliary functions for global optimization are proposed. These two auxiliary functions possess all characters of tunnelling functions and filled functions under certain general assumptions. Thus, they can be considered as the unification of filled function and tunnelling function. Moreover, the process of tunneling or filling for global optimization can be unified as the minimization of such auxiliary functions. Result of numerical experiments shows that such two auxiliary functions are effective.

关键词： Nonlinear programming global optimization filled function tunnelling function unification

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A Buffer Scheduling Method Based on Message Priority in Delay Tolerant Networks

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Journal of Computer Science & Technology 2016年第6期31卷 1228-1245页

作者： En Wang yong-jian yang Jie Wu Wen-Bin Liu Department of Computer Science and Technology Jilin University Changchun 130012 China Department of Computer and Information Sciences Temple University Philadelphia 19122 U.S.A. Department of Software Jilin University Changchun 130012 China

Routing protocols in delay tolerant networks usually utilize multiple message copies to guarantee the message delivery, in order to overcome unpredictable node mobility and easily-interrupted connections. A store-carry-and-forward paradigm was also proposed to further improve the message delivery. However, excessive message copies lead to the shortage of buffer and bandwidth. The spray and wait routing protocol has been proposed to reduce the network overload caused by the buffer and transmission of unrestricted message copies. However, when a node＇s buffer is quite constrained, there still exist congestion problems. In this paper, we propose a message scheduling and drop strategy on spray and wait routing protocol （SDSRP）. To improve the delivery ratio, first of all, SDSRP calculates the priority of each message by evaluating the impact of both replicating and dropping a message copy on delivery ratio. Subsequently, scheduling and drop decisions are made according to the priority. In order to further increase delivery ratio, we propose an improved message scheduling and drop strategy on spray and wait routing protocol （ISDSRP） through enhancing the accuracy of estimating parameters. Finally, we conduct extensive simulations based on synthetic and real traces in ONE. The results show that compared with other buffer management strategies, ISDSRP and SDSRP achieve higher delivery ratio, similar average hopcounts, and lower overhead ratio.

关键词： delay tolerant network spray and wait buffer scheduling priority

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An Efficient Message Dissemination Scheme for Minimizing DeliveryDelay in Delay Tolerant Networks

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Journal of Computer Science & Technology 2018年第6期33卷 1101-1124页

作者： En Wang Wei-Shih yang yong-jian yang Jie Wu Wen-Bin Liu Department of Computer Science and Technology Jilin University Changchun 130012 China Department of Mathematics Temple University Philadelphia PA 19122 U.S.A. Department of Computer and Information Science Temple University Philadelphia PA 19122 U.S.A.

Delay tolerant networks （DTNs） are a kind of sparse and highly mobile wireless networks, where no stableconnectivity guarantee can be assumed. Most DTN users have several points of interest （PoIs）, and they enjoy disseminatingmessages to the other users of the same PoI through WiFi. In DTNs, some time-sensitive messages （disaster warnings, searchnotices, etc.） need to be rapidly propagated among specific users or areas. Therefore, finding a path from the source tothe destination with the shortest delay is the key problem. Taking the dissemination cost into consideration, we proposean efficient message dissemination strategy for minimizing delivery delay （MDMD） in DTNs, which first defines the user＇sactiveness according to the transiting habit among different PoIs. Furthermore, depending on the activeness, an optimaluser in each PoI is selected to constitute the path with the shortest delay. Finally, the MDMD with inactive state （on theway between PoIs） is further proposed to enhance the applicability. Simulation results show that, compared with otherdissemination strategies, MDMD achieves the lowest average delay, and the comparable average hopcounts, on the premisethat the delivery ratio is guaranteed to be 100% by the sufficient simulation time.

关键词： delay tolerant network (DTN) point of interest (PoI) dissemination strategy minimizing delay

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Discrete Global Optimization Problems with a Modified Discrete Filled Function

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Journal of the Operations Research Society of China 2015年第3期3卷 297-315页

作者： yong-jian yang Meng-Li He Yue-Lin Gao Department of Mathematics Shanghai UniversityShanghai 200444China Institute of Information and System Science Beifang University for NationalitiesYinchuan 750021China

This paper considers discrete global optimization *** traditional definition of the discrete filled function is modified in this *** on the modified definition,a new discrete filled function is presented and an algorithm for discrete global optimization is developed from the discrete filled *** experiments reported in this paper on several test problems with up to 200 variables have demonstrated the efficiency of the algorithm.

关键词： Filled function method Discrete global optimization Nonlinear integer programming

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Optimization Methods for Mixed Integer Weakly Concave Programming Problems

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Journal of the Operations Research Society of China 2014年第2期2卷 195-222页

作者： Zhi-you Wu Fu-sheng Bai yong-jian yang Feng jiang School of Mathematics Chongqing Normal UniversityChongqing 401331China School of Information Technology and Mathematical Sciences Federation University AustraliaBallaratVIC 3353Australia Department of Mathematics Shanghai UniversityShanghai 200444China

In this paper,we consider a class of mixed integer weakly concave programming problems(MIWCPP)consisting of minimizing a difference of a quadratic function and a convex function.A new necessary global optimality conditions for MIWCPP is presented in this paper.A new local optimization method for MIWCPP is designed based on the necessary global optimality conditions,which is different from the traditional local optimization method.A global optimization method is proposed by combining some auxiliary functions and the new local optimization ***,numerical examples are also presented to show that the proposed global optimization method for MIWCPP is efficient.

关键词： Global optimality conditions Local optimization method Global optimization method Mixed integer weakly concave programming problems

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Determination of phenolic whitening agents in cosmetics by micellar electrokinetic capillary chromatography with amperometric detection

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Chinese Chemical Letters 2013年第7期24卷 636-638页

作者： Wei Jin Wei-Yu Wang Yu-Lian Zhang yong-jian yang Qing-Cui Chu jian-Nong Ye Department of Chemistry East China Normal University Shanghai Institute for Food and Drug Control

A sensitive method for simultaneous determination of six phenolic whitening agents, including arbutin, phenol, resorcinol, hydroquinone, kojic acid, and salicylic acid in cosmetics has been developed using micellar electrokinetic capillary chromatography with amperometric detection （MECC-AD）. Effects of several factors, such as the pH value and concentration of running buffer, potential applied to the working electrode, separation voltage, and injection time were investigated to obtain optimum conditions for separation and detection. With a 75 cm long fused-silica capillary tube, well-defined separation of six phenolic compounds was achieved in 10 mmol/L SDS/40 mmol/L H3BO3-Na2B407 running buffer （pH 9.0）. Good linear relationship was obtained for each analyte over three orders of magnitude with correlation coefficients （r2） between 0.9985 and 0.9994, and the detection limit （S/N = 3） ranged from 0.04 p^g/mL to 0.45 p^g/mL. The proposed method has been successfully applied for the determination of phenolic whitening agents in real cosmetic samples with satisfactory results, providing an alternative monitoring method for cosmetics safety regulation.

关键词： Micellar electrokinetic capillary chromatography Amperometric detection Phenolic whitening agents Cosmetics

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Variability Analysis for a Two-station Queueing Network in Heavy Traffic with Arrival Processes Driven by Queues

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 445-466页

作者： jian CAO yong-jiang GUO Kai-ming yang School of Science Beijing University of Posts and TelecommunicationsBeijing 100876China

The law of the iterated logarithm(LIL)for the performance measures of a two-station queueing network with arrivals modulated by independent queues is developed by a strong approximation *** convenience,two arrival processes modulated by queues comprise the external system,all others are belong to the internal *** is well known that the exogenous arrival has a great influence on the asymptotic variability of performance measures in *** the considered queueing network in heavy traffic,we get all the LILs for the queue length,workload,busy time,idle time and departure processes,and present them by some simple functions of the primitive *** LILs tell us some interesting insights,such as,the LILs of busy and idle times are zero and they reflect a small variability around their fluid approximations,the LIL of departure has nothing to do with the arrival process,both of the two phenomena well explain the service station’s situation of being busy all the *** external system shows us a distinguishing effect on the performance measures:an underloaded(overloaded,critically loaded)external system affects the internal system through its arrival(departure,arrival and departure together).In addition,we also get the strong approximation of the network as an auxiliary result.

关键词： two-station queueing network the law of the iterated logarithm(LIL) strong approximation fluid approximation

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