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农业产业化中的粪肥排放风险研究——以德国为例

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湖北农业科学 2018年第18期57卷 125-127,140页

作者：金菲利普.舒马赫苏永伟马丁.弗兰兹张跃强德国弗希塔大学德国弗希塔49377 中南财经政法大学武汉430073 德国奥斯纳布吕克大学德国奥斯纳布吕克49074 武汉纺织大学武汉430200

德国是农业高度发达的国家。农业产业化导致动物养殖规模不断扩大,田地里粪肥的排放量不仅大量增加,且有扩散的趋势,从而带来严重的环境污染问题,这不仅对人们的健康,而且对未来生产的发展均造成了很大的风险。研究介绍了德国农业产业... 详细信息

德国是农业高度发达的国家。农业产业化导致动物养殖规模不断扩大,田地里粪肥的排放量不仅大量增加,且有扩散的趋势,从而带来严重的环境污染问题,这不仅对人们的健康,而且对未来生产的发展均造成了很大的风险。研究介绍了德国农业产业化的基本情况,并以奥登博堡-明斯特兰德为例,对农业产业化中动物的粪肥排放风险进行识别,给出了降低农业产业化中的粪肥排放风险的可行建议。

关键词：农业产业化粪肥风险识别德国

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PEMFC极化曲线半经验模型的改进

电池 2015年第4期45卷 179-181页

作者：李平童晓敏郝冬侯永平同济大学新能源汽车工程中心上海201804 上海机动车检测中心上海201805

根据实验测得的数据,对燃料电池的极化曲线进行特性分析,归纳建模方法,在kim模型和Fraser模型的基础上,针对小电流密度区间拟合精度低和拟合参数过多的问题,修正了活化损耗项,提出了改进的半经验模型。比较3个模型拟合结果的鲁棒性和精... 详细信息

根据实验测得的数据,对燃料电池的极化曲线进行特性分析,归纳建模方法,在kim模型和Fraser模型的基础上,针对小电流密度区间拟合精度低和拟合参数过多的问题,修正了活化损耗项,提出了改进的半经验模型。比较3个模型拟合结果的鲁棒性和精确性,建立的半经验模型拟合精度更高,实用性更强。

关键词：燃料电池极化曲线半经验模型

人间和自然的相生与融合——21世纪生态界危机和韩国儒学

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江南大学学报（人文社会科学版） 2015年第2期14卷 5-11页

作者：金世贞韩国忠南大学校

儒教内含着丰富的人与自然和谐共处的有机体思考方式和生态论式要素。这种要素为克服机械式世界观、人类肆意破坏大自然提供了理论基础,同时也为树立生态中心主义理论的形成提供了可能性。韩国的儒教也不例外。文章试图通过对韩国性理... 详细信息

儒教内含着丰富的人与自然和谐共处的有机体思考方式和生态论式要素。这种要素为克服机械式世界观、人类肆意破坏大自然提供了理论基础,同时也为树立生态中心主义理论的形成提供了可能性。韩国的儒教也不例外。文章试图通过对韩国性理学者栗谷李珥、阳明学者霞谷郑齐斗,还有实学者湛軒洪大容及燕巖朴趾源等学者们思想的分析,找出其中有机体的、生态论的要素,为"韩国生态儒教"的确立提供基础。性理学者栗谷主张天地万物和人是同体,宇宙自然是一个有生命力的有机体,认为人类的生命源于宇宙自然,追求人与自然合一。在栗谷那里,人类被定义为赋予了以天地之心去照顾和养育自然的义务的存在。人类主体、能动地参与天地的化育中去,达到自然和人类合二为一的时候才能真正感受到乐趣(真乐)。阳明学者霞谷则主张人类和万物的同一性和一体性,把人类的心规定为天地之灵,即与万物感应的主体。人类通过生生不息的仁体的发显和展开来参与到宇宙自然万物的创生、养育过程中,来实现生命的本质,忠实履行天地之灵的作用。在性理学和阳明学看来,人类不是征服自然的主体,更不是自然的支配者。也不像在生态中心主义主张的那样,被赋予了同自然物等同的价值,作为自然的一部分生活的寒酸的存在。人类是在这个世界上最优越的存在,所以被称为天地之心或天地之灵,同时也被赋予了保护和养育自然的义务和责任。这种思考既能克服人类中心主义把自然看作是道具的弊端,也可以避免生态中心主义忽视人类价值的缺陷。实学家湛轩和燕严把自然物视为"活物",在重视人类和自然的有机统一关系方面与栗谷或霞谷持有类似的观点。但与栗谷和霞谷把人类规定为天地之心或天地之灵相比,湛轩和燕严则主张从天的立场上来看人和事物时二者的存在是平等,即人与事物的均等性,并提示了人与自然在平等的条件下互相尊重、互相帮助、互相依靠、相辅相助、共存共生的原理。人物均思想与生态学的平等主义相通,相生的原理和生态主义者的共生的原理也是一致的。这种认为人和事物平等的思考不仅是对‘自然存在物的尊重’,而且更进一步讲是‘追求人类和自然存在的和谐和共存’,为克服人类中心主义提供了契机。而且也可以避免性理学者们一不小心会倾向人类中心主义的顾虑,但有必要过于倾向于人均等而造成不利的影响。

关键词：韩国儒学环境哲学生态意识栗谷霞谷燕巖湛轩

Phase Ⅱ study of R-CVP followed by rituximab maintenance therapy for patients with advanced marginal zone lymphoma:consortium for improving survival of lymphoma(CISL)study

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Cancer Communications 2019年第1期39卷 526-535页

作者： Sung yong Oh Won Seog kim Jin Seok kim Seok Jin kim Dok Hyun Yoon Deok-Hwan Yang Won Sik Lee Hyo Jung kim Ho-Young Yhim Seong Hyun Jeong Jong Ho Won Suee Lee Jee Hyun Kong Sung-Nam Lim Jun Ho Ji Kyung A.Kwon Gyeong-Won Lee Jae Hoon Lee Ho Sup Lee Ho-Jin Shin Cheolwon Suh Department of Internal Medicine Dong-A University HospitalBusan 49201Republic of Korea Department of Medicine Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351Republic of Korea Division of Hematology Department of Internal MedicineYonsei University College of MedicineSeoul 03722Republic of Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSongpa-guSeoul 05505Republic of Korea Department of Hematology-Oncology Chonnam National University Hwasun HospitalHwasun 58128Republic of Korea Department of Hematology Busan Paik HospitalInje University College of MedicineBusan 04511Republic of Korea Department of Internal Medicine Hallym University Sacred Heart HospitalHallym University College of MedicineAnyang 14068Republic of Korea Department of Internal Medicine Chonbuk National University HospitalJeonju 54907Republic of Korea Department of Hematology-Oncology Ajou University School of MedicineSuwon 16499Republic of Korea Department of Internal Medicine Soonchunhyang University Seoul HospitalSoonchunhyang University College of MedicineSeoul 04401Republic of Korea Division of Hematology-Oncology Department of Internal MedicineWonju Severance Christian HospitalYonsei University College of MedicineWonju 26426Republic of Korea Department of Internal Medicine Haeundae Paik HospitalInje University College of MedicineBusan 48108Republic of Korea Division of Hematology and Oncology Department of Internal MedicineSamsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Republic of Korea Division of Hematology-Oncology Department of Internal MedicineDongnam Institute of Radiological and Medical SciencesBusan 46033Republic of Korea Division of Hematology-Oncology Department of Internal MedicineGyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Republic of Korea Department of Internal Medicine Gachon University Gil Medical CenterIncheon 21565Republic of

Background:The response rate and survival improvement for rituximab,a CD20-targeting monoclonal antibody,have been demonstrated in marginal zone lymphoma(MZL)as monotherapy and in combination with chemotherapeutic regimens,yet relapses still occur despite treatment ***,extending the period of remission in MZL patients remains an essential *** multicenter,single-arm,open-label phase II study evaluated the survival efficacy of 2 years of rituximab-maintenance therapy in patients with stage III-IV CD20-positive MZL who had responded to first-line R-CVP(rituximab,cyclophosphamide,vincristine,and prednisolone).The objective of this study was to determine whether rituximab maintenance following R-CVP warrants further ***:Prior to rituximab-maintenance therapy,patients received 6-8 cycles of first-line R-CVP therapy for stage III-IV ***(375 mg/m^(2)),cyclophosphamide(750 mg/m^(2)),and vincristine(1.4 mg/m^(2);maximum 2 mg)were administered via an intravenous infusion on day 1 of each 3-week cycle,while oral prednisolone(100 mg)was given on days 1-5 of each 3-week *** patients who achieved complete response(CR),partial response(PR),or stable disease(SD)to R-CVP treatment,were prescribed rituximab-maintenance therapy which was administered intravenously at a dose of 375 mg/m^(2) every 8 weeks for up to 12 *** primary endpoint was progression-free survival(PFS).Secondary endpoints were overall survival(OS)and treatment ***:47 patients were enrolled,of whom,45(96%)received rituximab-maintenance ***(33%)patients had nodal *** R-CVP first-line therapy,20(44%),22(49%),and 3(7%)patients achieved CR,PR,and SD,*** a median follow-up of 38.2 months,their observed 3-year PFS rate was 81%.During the rituximab-maintenance,6 PR and 1 SD patients achieved CR following the administration of *** LDH and the presence of B symptoms were found to be significant prognostic fac

关键词： Marginal zone Lymphoma Advanced stage Rituximab Cyclophosphamide Vincristine Maintenance Multicenter Open label Survival

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

血清miR-494表达水平预测心脏术后AKI患儿的预后价值

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中华危重病急救医学 2019年第12期31卷 1469-1473页

作者：吴日暖吴用杨丽霞邓颖云陈东旭三亚市人民医院儿科 572000

目的探讨血清微小RNA-494(miR-494)表达水平对心脏术后急性肾损伤(AKI)患儿的预后预测价值.方法选择2016年1月至2019年3月三亚市人民医院收治的116例先天性心脏病(先心病)体外循环手术后并发AKI的患儿.所有患儿均于术后采用实时荧光定... 详细信息

目的探讨血清微小RNA-494(miR-494)表达水平对心脏术后急性肾损伤(AKI)患儿的预后预测价值.方法选择2016年1月至2019年3月三亚市人民医院收治的116例先天性心脏病(先心病)体外循环手术后并发AKI的患儿.所有患儿均于术后采用实时荧光定量聚合酶链反应(RT-qPCR)检测血清miR-494表达,用酶联免疫吸附试验(ELISA)检测血清中性粒细胞明胶酶相关脂质运载蛋白(NGAL)及肾损伤分子-1(kim-1)水平.根据28 d预后将患儿分为存活组和死亡组,比较两组患儿一般资料及血清miR-494、NGAL、kim-1水平.采用多因素Logistic回归分析心脏术后AKI患儿死亡的危险因素;受试者工作特征曲线(ROC)分析血清miR-494、NGAL及kim-1水平预测心脏术后AKI患儿预后的价值;Pearson相关性分析血清miR-494表达水平与NGAL、kim-1的相关性.结果116例先心病体外循环手术后并发AKI患儿28 d死亡27例,存活89例.与存活组比较,死亡组患儿紫绀比例显著升高,血液灌流比例显著下降,体外循环时间、术后机械通气时间明显延长,术后血糖水平明显升高,其他一般资料差异无统计学意义.死亡组血清miR-494、NGAL及kim-1水平均明显高于存活组〔miR-494(2^-ΔΔCt):3.75±1.28比1.48±0.71,NGAL(mg/L):583.60±52.72比320.52±31.84,kim-1(μg/L):30.53±6.38比17.40±3.72,均Pkim-1(OR=1.805,95%CI为1.213~3.106,Pkim-1均可预测心脏术后AKI患儿死亡,ROC曲线下面积(AUC)分别为0.868、0.857、0.819;三者联合预测心脏术后AKI患儿死亡的AUC最大,为0.964(95%CI为0.908~0.997),其敏感度为97.0%,特异度为91.8%.相关性分析显示,死亡组血清miR-494表达水平与NGAL、kim-1均呈显著正相关(r1=0.902、r2=0.873,均Pkim-1水平对患儿预后具有较高的预测价值.

关键词：急性肾损伤心脏手术儿童微小RNA-494 预后预测

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金脉刺桐嫩枝上刺桐姬小蜂虫瘿分布规律研究

环境昆虫学报 2014年第4期36卷 655-660页

作者：刘春燕黄茂俊陆永跃广东省林业有害生物防治检疫办公室广州5101732 华南农业大学昆虫学系广州510642

刺桐姬小蜂Quadrastichus erythrinae kim是重要外来入侵害虫,危害刺桐属多种植物。本文调查研究了金脉刺桐嫩枝上刺桐姬小蜂虫瘿的数量分布和空间格局。结果显示,金脉刺桐嫩枝上靠近生长点(芽头)一端刺桐姬小蜂虫瘿数量较多,15 cm以内... 详细信息

刺桐姬小蜂Quadrastichus erythrinae kim是重要外来入侵害虫,危害刺桐属多种植物。本文调查研究了金脉刺桐嫩枝上刺桐姬小蜂虫瘿的数量分布和空间格局。结果显示,金脉刺桐嫩枝上靠近生长点(芽头)一端刺桐姬小蜂虫瘿数量较多,15 cm以内占90%以上,距离越远越少,其虫瘿数量比率(Y)和枝条长度(X)关系方程为Y=72.577e-0.138X。对频次分布的分析结果显示,刺桐嫩枝上虫瘿主要以虫瘿集体形式出现。获得的虫瘿空间格局主要参数平均拥挤度M*、丛生指数I、聚块性指数M*/M等均显著大于1,表明虫瘿是聚集分布且聚集程度较强。建立的Iwao M*-M方程为M*=1.75+3.51M、Taylor幂函数法则模型为lg s2=0.554+1.828lgx珋。

关键词：刺桐姬小蜂金脉刺桐虫瘿分布空间格局

微量元素Sb对AZ31合金组织与蠕变性能的影响

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沈阳工业大学学报 2005年第3期27卷 257-260,273页

作者：杨景红田素贵于兴福张禄廷孙根荣金敬铉沈阳工业大学材料科学与工程学院沈阳110023 韩国机械与材料研究院材料技术部

通过蠕变曲线的测定、x 射线衍射分析及SEM、TEM形貌观察,研究了微量元素Sb对AZ31合金的组织结构及蠕变性能的影响.结果表明:在AZ31合金中加入元素Sb后,有效降低了合金应变量及稳态应变速率.当加入0 84%Sb后,使合金的稳态蠕变速率降低了... 详细信息

通过蠕变曲线的测定、x 射线衍射分析及SEM、TEM形貌观察,研究了微量元素Sb对AZ31合金的组织结构及蠕变性能的影响.结果表明:在AZ31合金中加入元素Sb后,有效降低了合金应变量及稳态应变速率.当加入0 84%Sb后,使合金的稳态蠕变速率降低了2 5倍,显著提高了合金的蠕变寿命.高体积分数(～20%)第二相的存在,特别是合金中弥散分布高熔点的Mg3Sb2相,在高温蠕变期间可有效地阻碍位错运动,也是该合金具有较好蠕变抗力的主要原因.

关键词：元素Sb AZ31合金组织结构位错蠕变抗力

尿液NGAL、kim-1、TFF3联合检测对肝硬化患者急性肾小管坏死的诊断价值

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世界华人消化杂志 2023年第19期31卷 808-815页

作者：龚艳清赵莹贾艳会李熳江勇天津医科大学第二医院消化内科天津市300211 天津市第三中心医院检验科天津市300100

背景急性肾损伤(acute kidney injury,AKI)是失代偿期肝硬化患者常见的并发症,临床死亡率高且预后较差,其中急性肾小管坏死(acute tubular necrosis,ATN)预后最差,及时准确地识别ATN是临床难以解决的问题,既往研究显示,尿液中性粒细胞... 详细信息

背景急性肾损伤(acute kidney injury,AKI)是失代偿期肝硬化患者常见的并发症,临床死亡率高且预后较差,其中急性肾小管坏死(acute tubular necrosis,ATN)预后最差,及时准确地识别ATN是临床难以解决的问题,既往研究显示,尿液中性粒细胞明胶酶相关脂质运载蛋白(neutrophil gelatinase-associated lipocalin,NGAL)、三叶因子3(trefoil factor 3,TFF3)及肾损伤因子-1(kidney injury molecule-1,kim-1)对于肝硬化中ATN与其他类型的AKI有潜在的鉴别诊断价值,但诊断效能较低,仍不能进入临床应用,需进一步探究指标间联合检测能否提升生物标志物对于肝硬化合并ATN的诊断效能.目的分析尿NGAL、尿kim-1、尿TFF3及两两指标间联合检测在肝硬化合并AKI患者中对于ATN的鉴别诊断价值,同时对尿NGAL等指标对于ATN鉴别诊断的临界值行进一步研究.方法选取失代偿期肝硬化患者190例,其中合并AKI患者108例,根据AKI病因分成不同亚组,包括33例肾前性氮质血症,27例肝肾综合征急性肾损伤型及48例ATN,探究尿NGAL、尿TFF3、尿kim-1及指标间两两联合在肝硬化合并AKI患者中对于ATN的鉴别诊断价值.结果尿NGAL对于肝硬化合并AKI患者中ATN的鉴别诊断价值较高,受试者工作曲线下面积(area under the curve,AUC)是0.902,诊断临界值为271.8 ug/g Cr时,敏感度为81.3%,特异性为85.0%.指标联合可提高鉴别诊断能力,其中尿NGAL联合尿TFF3的诊断能力最强(AUC=0.933,敏感度为85.4%,特异性为88.3%).结论尿NGAL、尿kim-1、尿TFF3对于鉴别肝硬化合并AKI患者中ATN与其他类型AKI有重要价值,2项指标间的联合检测可进一步提升诊断效能,值得进一步研究及临床推广.

关键词：肝硬化急性肾损伤 NGAL TFF3 kim-1 联合检测急性肾小管坏死