检索结果-南通市图书馆

Journal of Mountain Science 2024年第8期21卷 2844-2854页

作者： CHEN Wenhua XIANG tian School of Civil Engineering Beijing Jiaotong UniversityBeijing 202303China

Water freezing in rock fractures causes volumetric expansion and fracture development through frost *** study introduces a novel analytical model to investigate how uneven freezing force and surrounding rock pressure influence fracture initiation,based on mass conservation,elasticity,and water-ice phase transition principles.A model for rock fracture initiation considering freezing temperature,uneven freezing expansion,in-situ stress,and lateral pressure was proposed based on fracture *** for stress intensity factors were developed and validated using the phase field *** effects of rock elastic modulus anisotropy and critical fracture energy density on fracture initiation were also *** results show that the values of KI and KII exhibit an upward trend as the freezing temperature,uneven expansion,in-situ stress,and lateral pressure *** uneven freezing expansion has the most significant influence on KI and KII values among these *** the uneven freezing expansion coefficient increases to 0.5,the fracture initiation mode shifts from tensile fracture to shear *** the lateral pressure coefficient increases to 1,the fracture initiation mode shifts from tensile fracture to shear *** elastic modulus anisotropy causes fractures to propagate in a clockwise direction,forming a'butterfly'*** fracture energy density an isotropy causes counterclockwise deviation in propagation direction,resulting in branching paths and an'H'-shaped pattern.

关键词： Rock fractures Fracture water Uneven freezing expansion Phase field method Initiation angle Anisotropy

Surface engineering of Li-and Mn-rich layered oxides for superior Li-ion battery

在线全文

学校读者我要写书评

暂无评论

Tungsten 2024年第1期6卷 259-268页

作者： Lu-Xiang Ma tian-Dong Chen Chun-Xi Hai Sheng-De Dong Xin He Qi Xu Hang Feng AXin Ji-tao Chen Yuan Zhou College of Materials and Chemistry and Chemical Engineering Chengdu University of TechnologyChendu 610000China Qinghai Building and Materials Research Co. LtdXining 810000China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

The Li-and Mn-rich layered oxides(R-LNCM)are considered as promising cathode materials for high-energy density lithium-ion batteries(LIBs).However,the interface side reaction aggravates the voltage and capacity fading between cathode material and electrolyte at high voltage,which severely hinders the practical application of LIB ***,lithium polyacrylate(LiPAA)as the binder and coating agent is applied to suppress the voltage and capacity fading of R-LNCM *** flexible LiPAA layers with high elasticity are capable of impeding cathode cracks on the particle surface via mechanical stress ***,superior voltage and capacity fading suppression on R-LNCM electrode is finally *** a result,LiPAA-R-LNCM cathode exhibits a remarkable specific capacity of 186 mA·h·g^(-1)with~73%retention at 1℃after ***,the corresponding average discharge potential is maintained to~3.1 V with only~0.4 V falling.

关键词： LiPAA interphase layer Interface side reaction Cathode cracks Capacity and voltage fading suppression Liand Mn-rich cathode

Research on the Impact of Equity Pledge on Company Value

在线全文

学校读者我要写书评

暂无评论

Proceedings of Business and Economic Studies 2024年第4期7卷 60-65页

作者： tao Zhang Xuxu Zhu Jie tian Hebei GEO University Shijiazhuang 050030China

This article aims to provide a literature review on the impact of equity pledges on corporate value,and to explore in depth the application of equity pledges as a financial tool in corporate governance and capital operation,as well as its multidimensional impact on corporate *** reviewing and analyzing relevant literature both domestically and internationally,this article first defines the basic concept of equity pledges and then elaborates on the impact mechanism of equity pledges on company value from both positive and negative *** terms of positive impact,this article explores how equity pledges can promote corporate financing,optimize capital structure,and enhance the control of major shareholders over the *** terms of negative impacts,the possible control risk,market risk,and potential damage to the interests of small and medium-sized shareholders brought about by equity pledges were ***,this article also discusses the differences in the impact of equity pledges on company value in different scenarios and proposes corresponding policy recommendations and research prospects.

关键词： Equity pledge Company value Financing Corporate governance Market risk

Rapamycin Potentiates the Antitumor Effect of 5-Fluorouracil in Colon Cancer by Enhancing Autophagy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第7期8卷 152-160页

作者： Xiaoming tian Youjun He tao Hao Feicheng City People’s Hospital Shandong271000China Department of Colorectal Hernia Surgery Binzhou Medical University HospitalShandong256600China

Objective:To investigate whether the mTOR inhibitor rapamycin can enhance the growth suppression effect of 5-fluorouracil(5-FU)on colon cancer ***:CCK8 assays were used to examine cell *** cytometry and Western blotting were employed to detect cell proliferation,apoptosis,and related ***:The combination of rapamycin and 5-FU exhibited greater cytotoxicity in cells compared to rapamycin or 5-FU ***,cells in the G0/G1 phase increased while cells in the S phase decreased in the combination group,consistent with changes in the levels of Cyclin D1 and *** enhanced 5-FU-induced apoptosis in vitro by inducing caspase-dependent apoptosis,which is Bax/Bcl-2 ***:The combination of rapamycin and 5-FU showed a significant synergistic anticancer effect by enhancing *** study supports that the combination of rapamycin with 5-FU is an effective and feasible approach for colorectal cancer treatment.

关键词： Colorectal cancer Proliferation Apoptosis Autophagy Rapamycin

A privacy-preserving vehicle trajectory clustering framework

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2024年第7期25卷 988-1002页

作者： Ran tian Pulun GAO Yanxing LIU College of Computer Science&Engineering Northwest Normal UniversityLanzhou 730070China

As one of the essential tools for spatio‒temporal traffic data mining,vehicle trajectory clustering is widely used to mine the behavior patterns of ***,uploading original vehicle trajectory data to the server and clustering carry the risk of privacy ***,one of the current challenges is determining how to perform vehicle trajectory clustering while protecting user *** propose a privacy-preserving vehicle trajectory clustering framework and construct a vehicle trajectory clustering model(IKV)based on the variational autoencoder(VAE)and an improved K-means *** the framework,the client calculates the hidden variables of the vehicle trajectory and uploads the variables to the server;the server uses the hidden variables for clustering analysis and delivers the analysis results to the *** IKV’workflow is as follows:first,we train the VAE with historical vehicle trajectory data(when VAE’s decoder can approximate the original data,the encoder is deployed to the edge computing device);second,the edge device transmits the hidden variables to the server;finally,clustering is performed using improved K-means,which prevents the leakage of the vehicle *** is compared to numerous clustering methods on three *** the nine performance comparison experiments,IKV achieves optimal or sub-optimal performance in six of the ***,in the nine sensitivity analysis experiments,IKV not only demonstrates significant stability in seven experiments but also shows good robustness to hyperparameter *** results validate that the framework proposed in this paper is not only suitable for privacy-conscious production environments,such as carpooling tasks,but also adapts to clustering tasks of different magnitudes due to the low sensitivity to the number of cluster centers.

关键词： Privacy protection Variational autoencoder Improved K-means Vehicle trajectory clustering

Numerical investigation on characteristics of interfacial wave of liquid film in gas-liquid two-phase flow using OpenFOAM

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第2期37卷 233-248页

作者： Xiaoqi MA Yueshe WANG Jiaming tian State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an 710049China

Liquid film cooling as an advanced cooling technology is widely used in space *** operation of liquid film along the rocket combustion inner wall is crucial for thermal protection of rocket *** stability of liquid film is mainly determined by the characteristics of interfacial wave,which is rarely investigated right *** to improve the stability of thin film has become a hot *** view of this,an advanced model based on the conventional Volume of Fluid(VOF)model is adopted to investigate the characteristics of interfacial wave in gas-liquid flow by using OpenFOAM,and the mechanism of formation and development of wave is revealed intuitively through numerical *** effects from gas velocity,surface tension and dynamic viscosity of liquid(three factors)on the wave are studied *** can be found that the gas velocity is critical to the formation and development of wave,and four modes of droplets generation are illustrated in this ***,a gas vortex near the gas-liquid interface can induce formation of wave easily,so changing the gas vortex state can regulate formation and development of ***’s more,the change rules of three factors influencing on the interfacial wave are obtained,and the surface tension has a negative effect on the formation and development of wave only when the surface tension coefficient is above the critical value,whereas the dynamic viscosity has a positive effect in this ***,the maximum height and maximum slope angle of wave will level off as the gas velocity ***,the maximum slope angle of wave is usually no more than 38°,no matter what happens to the three factors.

关键词： Interfacial wave Gas-liquid Two-phase flow VOF model OpenFOAM

Preclinical evaluation of cyclophosphamide and fludarabine combined with CD19 CAR-T in the treatment of B-cell hematologic malignancies in vivo

在线全文

学校读者我要写书评

暂无评论

Oncology Research 2024年第6期32卷 1109-1118页

作者： ZHIGANG XIA MENGYAO tian YUCAI CHENG WENFANG YI ZEFAN DU tianWEN LI YUCHEN WEN LINDI LI yong LIU CHUN CHEN Pediatric Hematology Laboratory Division of Hematology/OncologyDepartment of PediatricsThe Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhen518107China Scientific Research Center The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhen518107China

Background:Chimeric antigen receptor T(CAR-T)cell therapy has achieved marked therapeutic success in ameliorating hematological ***,there is an extant void in the clinical guidelines concerning the most effective chemotherapy regimen prior to chimeric antigen receptor T(CAR-T)cell therapy,as well as the optimal timing for CAR-T cell infusion *** and Methods:We employed cell-derived tumor xenograft(CDX)murine models to delineate the optimal pre-conditioning chemotherapy regimen and timing for CAR-T cell ***,transcriptome sequencing was implemented to identify the therapeutic targets and elucidate the underlying mechanisms governing the treatment ***:Our preclinical in vivo evaluation determined that a combination of cyclophosphamide and fludarabine,followed by the infusion of CD19 CAR-T cells five days subsequent to the chemotherapy,exerts the most efficacious therapeutic effect in B-cell hematological ***,RNA-seq data indicated that the therapeutic efficacy predominantly perturbs tumor cell metabolism,primarily through the inhibition of key mitochondrial targets,such as C-Jun Kinase enzyme(C-JUN).Conclusion:In summary,the present study offers critical clinical guidance and serves as an authoritative reference for the deployment of CD19 CAR-T cell therapy in the treatment of B-cell hematological malignancies.

关键词： CD19 CAR-T B-cell hematologic malignancies Metabolism In vivo

Interface property of dissimilar Ti-6Al-4V/AA1050 composite laminate made by non-equal channel lateral co-extrusion and heat treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第3期33卷 197-208页

作者： Juan Liao Mengmeng tian Xin Xue School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350116China

The purpose of this paper is to examine the effect of processing parameters and subsequent heat treatments on the microstructures and bonding strengths of Ti-6Al-4V/AA1050 laminations formed via a non-equal channel lateral co-extrusion *** microstructural evolution and growth mechanism in the diffusion layer were discussed further to optimize the bonding quality by appropriately adjusting process *** electron microscopes(SEM),energy dispersive spectrometer(EDS),and X-ray diffraction(XRD)were used to characterize interfacial diffusion *** shear test was used to determine the mechanical properties of the interfacial diffusion *** experimental results indicate that it is possible to co-extrusion Ti-6Al-4V/AA1050 compound profiles using non-equal channel lateral *** heat treatment processes affect the thickness of the diffusion *** the temperature and time of heat treatment increase,the thickness of the reaction layers increases ***,the shear strength of the Ti-6Al-4V/AA1050 composite interface is proportional to the diffusion layer *** is observed that a medium interface thickness results in superior mechanical performance when compared to neither a greater nor a lesser interface *** characterization of all heat treatments reveals that the only intermetallic compound observed in the diffusion layers is TiAl_(3).Due to the inter-diffusion of Ti and Al atoms,the TiAl_(3) layer grows primarily at AA1050/TiAl_(3) interfaces.

关键词： Shear strength Co-extrusion Heat treatment Microstructure Intermetallic compounds

A new method for evaluating the firing precision of multiple launch rocket system based on Bayesian theory

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第2期32卷 232-241页

作者： Yunfei Miao Guoping Wang Wei tian College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjingJiangsuChina Institute of Launch Dynamics Nanjing University of Science and TechnologyNanjingJiangsuChina

How to effectively evaluate the firing precision of weapon equipment at low cost is one of the core contents of improving the test level of weapon system.A new method to evaluate the firing precision of the MLRS considering the credibility of simulation system based on Bayesian theory is proposed in this *** of all,a comprehensive index system for the credibility of the simulation system of the firing precision of the MLRS is constructed combined with the group analytic hierarchy process.A modified method for determining the comprehensive weight of the index is established to improve the rationality of the index weight *** Bayesian posterior estimation formula of firing precision considering prior information is derived in the form of mixed prior distribution,and the rationality of prior information used in estimation model is discussed *** the simulation tests,the different evaluation methods are compared to validate the effectiveness of the proposed ***,the experimental results show that the effectiveness of estimation method for firing precision is improved by more than 25%.

关键词： Multiple launch rocket system Bayesian theory Simulation credibility Mixed prior distribution Firing precision

Women’s empowerment and food consumption:Evidence from female-headed households in Tanzania

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第2期23卷 457-467页

作者： Mosses Lufuke Xu tian College of Economics and Management Nanjing Agricultural UniversityNanjing 210095China Department of Economics The University of DodomaDodoma 41218Tanzania College of Economics and Management China Agricultural UniversityBeijing 100083China Academy of Global Food Economics and Policy China Agricultural UniversityBeijing 100083China

Despite the growing recognition of women’s increasing role in the household and corresponding empowerment programs in sub-Saharan Africa,intensive research on the relationship between women’s influence and household food consumption is *** the most recent(2017-2018)national household survey data from Tanzania,this study examined the influence of women’s empowerment on household food ***,we compared the monthly consumption of eight food categories between female-headed households(FHHs)and male-headed households(MHHs)using both descriptive statistics and the propensity score matching(PSM)***,we adopted the two-stage Linear Expenditure System and Almost Ideal Demand System model(LES-AIDS)to estimate income and price elasticities for the two household *** results show that FHHs consume bread and cereals,fish,oils and fats,vegetables,and confectionery(sugar,jam,honey,chocolate,etc.)more than ***,FHHs have a significantly higher income elasticity of demand for all food groups than *** are also more price elastic than MHHs in meat,fish,oils,fats,sugar,jam,honey,chocolate,etc.

关键词： women’s empowerment food consumption income elasticity price elasticity