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Clinical characteristics and analysis of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss in different ages

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World Journal of Clinical Cases 2024年第19期12卷 3760-3766页

作者： Yan-Zhuo Zhang Ya-Bo Wang Jing-Lei Fang Yue-Tang Wang Gui-Fang Li Ran-Ran Liu Shu-Jing Shi Chun-Hua Wang yong-tao tian Department of Otolaryngology Hebei Provincial Eye HospitalHebei Provincial Key Laboratory of OphthalmologyHebei Provincial Eye InstituteXingtai 054001Hebei ProvinceChina

BACKGROUND Numerous studies have found that patients experiencing sudden sensorineural hearing loss(SSHL),with or without accompanying vertigo,often show impaired vestibular ***,there is a dearth of studies analyzing vestibularevoked myogenic potentials(VEMPs)in SSHL patients across various age *** To investigate vestibular condition in SSHL patients across various age *** Clinical data of 84 SSHL patients were investigated ***,cervical vestibular evoked myogenic potentials(c-VEMPs),and ocular vestibular evoked myogenic potentials(o-VEMPs)were conducted on these *** assessed included the latencies of P1 and N1 waves,as well as the amplitudes of P1–N1 ***,the study evaluated the influence of factors such as sex,affected side,configuration of hearing loss,and presence of accompanying *** Among the 84 SSHL patients,no significant differences were observed among the three groups in terms of gender,affected side,and the presence or absence of *** II(aged 41–60 years)had the highest number of SSHL *** rates of absent o-VEMPs in the affected ears were 20.83%,31.58%,and 22.72%for the three age groups,respectively,with no statistically significant difference among *** rates of absent c-VEMPs in the affected ears were 8.3%,34.21%,and 18.18%for the three age groups,respectively,with significant *** the unaffected ears,there were differences observed in the extraction rates of o-VEMPs in the unaffected ears among the age *** the three age groups,no significant differences were noted in the three age groups in the latencies of P1 and N1 waves or in the amplitude of N1–P1 waves for c-VEMPs and o-VEMPs,either on the affected side or on the unaffected side,across the three age *** The extraction rate of VEMPs is more valuable than *** of the presence of vertigo,vestibular organs are involved in ***,SSHL pat

关键词： Sudden sensorineural hearing loss Cervical vestibular evoked myogenic potential Ocular vestibular evoked myogenic potential Vertigo Pure tone audiometry

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Theoretical analysis of the double-differential cross-sections of neutron,proton,deuteron,^(3)He,andαfor the p+^(6) Li reaction

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Nuclear Science and Techniques 2024年第3期35卷 181-197页

作者： Fang-Lei Zou Xiao-Jun Sun Jing-Shang Zhang Hai-Rui Guo Yin-Lu Han Rui-Rui Xu Xi tao Ji-Min Wang Xiao-Dong Sun Yuan tian tao Ye yong-Li Xu Chun-tian Liang College of Physics Guangxi Normal University541004 GuilinChina Guangxi Key Laboratory of Nuclear Physics and Nuclear Technology 541004 GuilinChina China Institute of Atomic Energy P.O.Box 275(41)102413 BeijingChina Institute of Applied Physics and Computational Mathematics 10094 BeijingChina College of Physics and Electronic Shanxi Datong University037009 DatongChina School of Science Tianjin Chengjian University300384 TianjinChina

Based on the unified Hauser–Feshbach and exciton model,which can describe the particle emission processes between discrete energy levels with energy,angular momentum,and parity conservations,a statistical theory of light nucleus reaction(STLN)is developed to calculate the double-differential cross-sections of the outgoing neutron and light charged particles for the proton-induced^(6) Li reaction.A significant difference is observed between the p+^(6) Li and p+^(7) Li reactions owing to the discrepancies in the energy-level structures of the *** reaction channels,including sequential and simultaneous emission processes,are analyzed in *** the double-differential cross-sections of the outgoing proton as an example,the influence of contaminations(such as^(1) H,^(7)Li,^(12)C,and^(16)O)on the target is identified in terms of the kinetic energy of the first emitted *** optical potential parameters of the proton are obtained by fitting the elastic scattering differential *** calculated total double-differential cross-sections of the outgoing proton and deuteron at E_(p)=14 MeV agree well with the experimental data for different outgoing ***,the mixed double differential cross-sections of^(3) He andαare in good agreement with the *** agreement between the measured data and calculated results indicates that the two-body and three-body breakup reactions need to be considered,and the pre-equilibrium reaction mechanism dominates the reaction *** on the STLN model,a PLUNF code for the p+^(6) Li reaction is developed to obtain an ENDF-6-formatted file of the double-differential cross-sections of the nucleon and light composite charged particles.

关键词： Statistical theory of light nucleus reaction p+^(6)Li reaction Light composite charged particle Double-differential cross-sections Two-body breakup Three-body breakup

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Long-term operation optimization of circulating cooling water systems under fouling conditions

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Chinese Journal of Chemical Engineering 2024年第1期65卷 255-267页

作者： Jiarui Liang yong tian Shutong Yang yong Wang Ruiqi Yin Yufei Wang School of Chemical Engineering and Environment China University of PetroleumBeijing102249China CHN Energy Xinjiang Chemical Co. LTDUrumqi830092China College of Mechanical and Transportation Engineering China University of PetroleumBeijing 102249China

Fouling caused by excess metal ions in hard water can negatively impact the performance of the circulating cooling water system(CCWS)by depositing ions on the heat exchanger's ***,the operation optimization of CCWS often prioritizes short-term flow velocity optimization for minimizing power consumption,without considering ***,low flow velocity promotes ***,it's crucial to balance fouling and energy/water conservation for optimal CCWS long-term *** study proposes a mixed-integer nonlinear programming(MINLP)model to achieve this *** model considers fouling in the pipeline,dynamic concentration cycle,and variable frequency drive to optimize the synergy between heat transfer,pressure drop,and *** optimizing the concentration cycle of the CCWS,water conservation and fouling control can be *** model can obtain the optimal operating parameters for different operation intervals,including the number of pumps,frequency,and valve local resistance *** experiments on cycle and environmental temperature reveal that as the cycle increases,the marginal benefits of energy/water conservation *** periods with minimal impact on fouling rate,energy/water conservation can be achieved by increasing the cycle while maintaining a low fouling ***,the proposed model has significant energy/water saving effects and can comprehensively optimize the CCWS through its incorporation of fouling and cycle optimization.

关键词： Computer simulation Circulating water system Fouling Concentration cycle Optimization Variable frequency drive

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Unveiling the Re,Cr,and I diffusion in saturated compacted bentonite using machine-learning methods

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Nuclear Science and Techniques 2024年第6期35卷 65-77页

作者： Zheng-Ye Feng Jun-Lei tian tao Wu Guo-Jun Wei Zhi-Long Li Xiao-Qiong Shi yong-Jia Wang Qing-Feng Li Department of Engineering Huzhou UniversityHuzhou 313000China Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006China College of Physics Science and Technology Shenyang Normal UniversityShenyang 110034China

The safety assessment of high-level radioactive waste repositories requires a high predictive accuracy for radionuclide diffusion and a comprehensive understanding of the diffusion *** this study,a through-diffusion method and six machine-learning methods were employed to investigate the diffusion of ReO_(4)^(−),HCrO_(4)^(−),and I−in saturated compacted bentonite under different salinities and compacted dry *** machine-learning models were trained using two *** dataset contained six input features and 293 instances obtained from the diffusion database system of the Japan Atomic Energy Agency(JAEA-DDB)and 15 *** other dataset,comprising 15,000 pseudo-instances,was produced using a multi-porosity model and contained eight input *** results indicate that the former dataset yielded a higher predictive accuracy than the *** gradient-boosting exhibited a higher prediction accuracy(R2=0.92)and lower error(MSE=0.01)than the other machine-learning *** addition,Shapley Additive Explanations,Feature Importance,and Partial Dependence Plot analysis results indicate that the rock capacity factor and compacted dry density had the two most significant effects on predicting the effective diffusion coefficient,thereby offering valuable insights.

关键词： Machine learning Effective diffusion coefficient Through-diffusion experiment Multi-porosity model Global analysis

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Associations of daily sedentary behavior,physical activity,and sleep with irritable bowel syndrome:A prospective analysis of 362,193 participants

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Journal of Sport and Health Science 2024年第1期13卷 72-80页

作者： Xu Gao Sifan tian Ninghao Huang Gang Sun tao Huang Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100191China Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Department of Gastroenterology and Hepatology First Medical Center of People's Liberation Army General HospitalBeijing 100853China

Background:Irritable bowel syndrome(IBS)substantially affects quality of life and requires early *** study aimed to elucidate the relationships between IBS and daily behaviors,including sedentary behavior(SB),physical activity(PA),and *** particular,it seeks to identify healthy behaviors to reduce IBS risk,which previous studies have rarely ***:Daily behaviors were retrieved from self-reported data of 362,193 eligible UK Biobank *** cases were determined by self-report or health care data according to RomeⅣ***:A total of 345,388 participants were IBS-free at baseline,during a median follow-up of 8.45 years,19,885 incident IBS cases were *** examined individually,SB and shorter(≤7 h/day)or longer(>7 h/day)sleep duration were each positively associated with increased IBS risk,and PA was associated with lower IBS *** isotemporal substitution model suggested that replacing SB with other activities could provide further protective effects against IBS *** people sleeping≤7 h/day,replacing 1 h of SB with equivalent light PA,vigorous PA,or sleep was associated with 8.1%(95%confidence interval(95%CI):0.901-0.937),5.8%(95%CI:0.896-0.991),and 9.2%(95%CI:0.885-0.932)reduced IBS risk,*** people sleeping>7 h/day,light and vigorous PA were associated with a 4.8%(95%CI:0.926-0.978)and a 12.0%(95%CI:0.815-0.949)lower IBS risk,*** benefits were mostly independent of genetic risk for ***:SB and unhealthy sleep duration are risk factors for IBS.A promising way to mitigate IBS risk for individuals sleeping≤7 h/day and for those sleeping>7 h/day appears to be by replacing SB with adequate sleep or vigorous PA,respectively,regardless of the genetic predisposition of IBS.

关键词： Irritable bowel syndrome Isotemporal substitution model Physical activity Sedentary behavior Sleep

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The relationship between interannual dry/wet changes and nomadic wars in the Hexi Corridor region of China during the period 241–1912 A.D.

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Science China Earth Sciences 2024年第6期67卷 1922-1931页

作者： Fei TANG Zhilin SHI Qinhua tian Xiaogang DU yong ZHANG Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Institute of Dunhuang Studies Lanzhou UniversityLanzhou 730020China National Climate Center China Meteorological AdministrationBeijing 100081China Longchanghe Station Gansu Qilian Mountain National Nature ReserveZhangye 734400China University of Chinese Academy of Sciences Beijing 100049China

The link between climate and war has long been a topic of great scientific and social *** this study,we investigate the influence of climate on warfare in China’s Hexi Corridor region since 241 *** the superposed epoch analysis of tree-ring data and historical war data,we observe a notable correlation between interannual dry-wet variations and wars instigated by nomadic groups in the Hexi ***,this relationship is dynamic and influenced by the region’s relative *** periods in which the Hexi Corridor was ruled by multiple regimes,wars tended to follow dry climatic conditions,which may be due to the fact that unusual drought during these periods likely heightened competition for resources and ***,during times of regional unity,wars were more likely to occur when climatic conditions were wet because the expansion of rangelands and the accumulation of resources helped fuel the nomads’outward *** findings underscore the complexity of the relationship between war and climate *** gain a more comprehensive understanding of this relationship,continuous,high-resolution historical temperature and humidity datasets with broader and more uniform coverage are needed across multiple *** addition,collecting and examining disaggregated historical war data for regions with distinct characteristics is essential.

关键词： Drought Interannual dry and wet variations War The Hexi Corridor Tree ring Nomadic groups

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Machine Learning-Aided Data Analysis in Single-Protein Conductance Measurement with Electron Tunneling Probes

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Chinese Journal of Chemistry 2024年第1期42卷 67-72页

作者： Yuxin Yang tao Jiang Ye tian Biaofeng Zeng Longhua Tang State Key Laboratoryof Extreme Photonics and Instrumentation College of Optical Science and EngineeringZhejiang University HangzhouZhejiang 310027China Nanhu Brain-computer Interface Institute HangzhouZhejiang 311100China State Key Laboratory of Fluid Power and Mechatronic Systems College of Mechanical EngineeringZhejiang University HangzhouZhejiang 310027China

The electrical tunneling sensors have excellent potential in the next generation of single-molecule measurement and sequencing technologies due to their high sensitivity and spatial resolution *** tunneling signals that have been measured at a high sampling rate may provide detailed molecular *** the extraordinarily large amount of data that has been gathered,it is still difficult to correlate signal transformations with molecular processes,which creates great obstacles for signal *** learning is an effective tool for data analysis that is currently gaining more *** has demonstrated promising results when used to analyze data from single-molecule electrical *** order to extract meaningful information from raw measurement data,we have combined intelligent machine learning with tunneling electrical *** the purpose of analyzing tunneling electrical signals,we investigated the clustering approach,which is a classic algorithm in machine learning.A clustering model was built that combines the advantages of hierarchical clustering and Gaussian mixture model ***,customized statistical algorithms were *** has been proven to efficiently gather molecular information and enhance the effectiveness of data analysis.

关键词： Tunneling sensor Single-molecule measurement Machine learning Single-protein conductance Molecular electrochemistry Nanotechnology Molecular electronics

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CO_(2)flooding in shale oil reservoir with radial borehole fracturing for CO_(2)storage and enhanced oil recovery

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Petroleum Science 2024年第1期21卷 519-534页

作者： Jia-Cheng Dai tian-Yu Wang Jin-tao Weng Kang-Jian tian Li-Ying Zhu Gen-Sheng Li State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China China National Oil and Gas Exploration and Development Company Limited Beijing100034China

This study introduces a novel method integrating CO_(2)flooding with radial borehole fracturing for enhanced oil recovery and CO_(2)underground storage,a solution to the limited vertical stimulation reservoir volume in horizontal well fracturing.A numerical model is established to investigate the production rate,reservoir pressure field,and CO_(2)saturation distribution corresponding to changing time of CO_(2)flooding with radial borehole fracturing.A sensitivity analysis on the influence of CO_(2)injection location,layer spacing,pressure difference,borehole number,and hydraulic fractures on oil production and CO_(2)storage is *** CO_(2)flooding process is divided into four *** in layer spacing will significantly improve oil production rate and gas storage ***,serious gas channeling can occur when the spacing is lower than 20 *** the pressure difference between the producer and injector,the borehole number,the hydraulic fracture height,and the fracture width can also increase the oil production rate and gas storage *** analysis shows that layer spacing and fracture height greatly influence gas storage and oil *** outcomes are expected to provide a theoretical basis for the efficient development of shale oil reservoirs in the vertical direction.

关键词： Shale oil Radial borehole fracturing Embedded discrete fracture model Enhanced oil recovery Carbon storage

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Fracture geometry and breakdown pressure of radial borehole fracturing in multiple layers

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Petroleum Science 2024年第1期21卷 430-444页

作者： Yu-Ning yong Zhao-Quan Guo Shou-Ceng tian Lu-Yao Ma tian-Yu Wang Mao Sheng National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Beijing Petroleum Machinery Company Limited CNPC Engineering Technology R&D Company LimitedBeijing102206China Smart Energy Co. LtdChina Xiongan GroupXiong’an New Area071000HebeiChina

Radial borehole fracturing that combines radial boreholes with hydraulic fracturing is anticipated to improve the output of tight oil and gas *** paper aims to investigate fracture propagation and pressure characteristics of radial borehole fracturing in multiple layers.A series of laboratory experiments with artificial rock samples(395 mm×395 mm×395 mm)was conducted using a true triaxial fracturing *** crucial factors corresponding to the vertical distance of adjacent radial borehole layers(vertical distance),the azimuth and diameter of the radial borehole are *** results show that radial borehole fracturing in multiple layers generates diverse fracture *** types of fractures are identified based on the connectivity between hydraulic fractures and radial *** vertical distance significantly influences fracture propagation perpendicular to the radial borehole *** increase in the vertical distance impedes fracture connection across multiple radial borehole layers and reduces the fracture propagation distance along the radial borehole *** azimuth also influences fracture propagation along the radial borehole *** the azimuth reduces the guiding ability of radial boreholes,which makes the fracture quickly curve to the maximum horizontal stress *** breakdown pressure correlates with diverse fracture geometries *** the fractures connect multi-layer radial boreholes,increasing the vertical distance decreases the breakdown *** the azimuth and increasing the diameter also decrease the breakdown *** extrusion force exists between the adjacent fractures generated in radial boreholes in multiple rows,which plays a crucial role in enhancing the guiding ability of radial boreholes and results in higher breakdown *** research provides valuable theoretical insights for the field application of radial borehole fracturing technology in tight oil and g

关键词： Multi-layer radial boreholes Hydraulic fracturing Fracture propagation Pressure characteristic

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Chemical derivatization strategies for enhancing the HPLC analytical performance of natural active triterpenoids

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Journal of Pharmaceutical Analysis 2024年第3期14卷 295-307页

作者： Xiao-Feng Huang Ying Xue Li yong tian-tian Wang Pei Luo Lin-Sen Qing Chengdu Institute of Biology Chinese Academy of SciencesChengdu610041China State Key Laboratory for Quality Research in Chinese Medicines Macao University of Science and TechnologyMacaoChina Sichuan Center for Disease Control and Prevention Chengdu610041China University of Chinese Academy of Sciences Beijing100049China

Triterpenoids widely exist in nature,displaying a variety of pharmacological *** triterpenoids in different matrices,especially in biological samples holds great ***-performance liquid chromatography(HPLC)has become the predominant method for triterpenoids analysis due to its exceptional analytical ***,due to the structural similarities among botanical samples,achieving effective separation of each triterpenoid proves challenging,necessitating significant improvements in analytical ***,triterpenoids are characterized by a lack of ultraviolet(UV)absorption groups and chromophores,along with low ionization efficiency in mass ***,routine HPLC analysis suffers from poor *** derivatization emerges as an indispensable technique in HPLC analysis to enhance its *** the structural characteristics of triterpenoids,various derivatization reagents such as acid chlorides,rhodamines,isocyanates,sulfonic esters,and amines have been employed for the derivatization analysis of *** review comprehensively summarized the research progress made in derivatization strategies for HPLC detection of ***,the limitations and challenges encountered in previous studies are discussed,and future research directions are proposed to develop more effective derivatization methods.

关键词： Triterpenoid HPLC Derivatization Quantification

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