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An ion-imprinted polymer supported by attapulgite with a chitosan incorporated sol-gel process for selective separation of Ce(Ⅲ)

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Chinese Chemical Letters 2009年第8期20卷 985-989页

作者： Chun Xiang Li Jian Ming Pan Jie Gao yong sheng yan Gan Qing Zhao School of Chemistry and Chemical Engineering Jiangsu University Zhenjiang 212013 China

The surface ion-imprinting concept and chitosan incorporated sol-gel process were applied to the synthesis of a new attapulgitesupported polymer for selective separation of Ce（III） from aqueous solution. The imprinting mechanism of prepared ion-imprinted polymer were discussed with the Characteristics of FT-IR and SEM. Results from the experiments of adsorption capacity and selectivity suggested that ion-imprinted polymer offered a fast kinetics for the adsorption of Ce（III） under the optimum conditions. Its maximum adsorption capacity was 38.02 mg/g, and the selective recognition towards Ce（III） was much higher than that of the non-imprinted polymer and attapulgite. The prepared functional polymer was shown to be promising for selective separation and enrichment of trace Ce（III） in environmental samples. ？2009 yong sheng yan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Attapulgite Chitosan Surface ion-imprinted Selective adsorption Ce(III)

Fabrication and evaluation of molecularly imprinted regenerated cellulose composite membranes via atom transfer radical polymerization

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Chinese Chemical Letters 2014年第2期25卷 273-278页

作者： Yi-Lin Wu yong-sheng yan Jian-Ming Pan Xiao-Hui Dai Wei-Dong Shi Min-Jia Meng School of Chemistry and Chemical Engineering Jiangsu University

A simple and effective method for surface molecularly imprinted composite membranes （MICMs） for artemisinin （Ars） based on regenerated cellulose membranes was first prepared through surface- initiated atom transfer radical polymerization （ATRP）, and the as-prepared MICMs were then evaluated as adsorbents for selective recognition and separation of Ars molecules. Batch rebinding studies were conducted to determine the specific adsorption equilibrium, kinetics and selective permeation performance. The adsorption capacity of MICMs toward Ars by the Langmuir isotherm model was 2.008 mgg-1, which was nearly 5.0 times higher than non-molecularly imprinted composite membranes （NICMs）. The kinetic property of MICMs was well-fitted by the pseudo-second-order rate equation. The selective permeation experiments were successfully investigated to prove the excellent selective permeation performance for Ars than the competitive analog （artemether）.

关键词： Molecularly imprinted compositemembranes Atom transfer radical polymerization Selective recognition Artemisinin

Overexpression of an F-box Protein Gene Reduces Abiotic Stress Tolerance and Promotes Root Growth in Rice

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Molecular Plant 2011年第1期4卷 190-197页

作者： yong-sheng yan Xiao-Ying Chen Kun yang Zong-Xiu Sun Ya-Ping Fu Yu-Man Zhang Rong-Xiang Fang State Key Laboratory of Plant Genomics Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China National Plant Gene Research Center Beijing 100101 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China Present address: School of Life Science and Technology University of Electronic Science and Technology of China Chengdu 610054 China State Key Laboratory of Rice Biology National Rice Research Institute Hangzhou 310006 China

As one of the largest gene families, F-box domain proteins have important roles in regulating various devel- opmental processes and stress responses. In this study, we have investigated a rice F-box domain gene, MAIF1. The MAIF1 protein is mainly localized in the plasma membrane and nucleus. MAIF1 expression is induced rapidly and strongly by abscisic acid （ABA） and abiotic stresses. MAIF1 expression is also induced in root tips by sucrose, independent of its hy- drolytic hexose products, glucose and fructose, and the plant hormones auxin and cytokinin. Overexpression of MAIF1 reduces rice ABA sensitivity and abiotic stress tolerance and promotes rice root growth. These results suggest that MAIF1 is involved in multiple signaling pathways in regulating root growth. Growth restraint in plants is an acclimatization strategy against abiotic stress, Our results also suggest that MAIF1 plays the negative role in response to abiotic stress possibly by regulating root growth.

关键词： Rice (Oryza sativa L.) F-box domain abscisic acid abiotic stress tolerance root growth.

Clinical profile and outcomes of atrial fibrillation in elderly patients with acute myocardial infarction

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Chinese Medical Journal 2008年第23期121卷 2388-2391页

作者： LI Kang HUO yong DING yan-sheng Department of Cardiology Peking University First Hospital Beijing 100034 China

Background Atrial fibrillation （AF） occurs commonly in patients with acute myocardial infarction （MI） and is associated with an increased long-term mortality. This study aimed to investigate the clinical characteristics and outcomes of AF in in-hospital elderly Chinese patients with acute MI. Methods A total of 967 patients with acute MI, aged 〉65 years, were categorized on the basis of the absence or presence of AF. Patients with documented AF were classified into two subgroups： the ongoing AF group and the new-onset AF group. We retrospectively evaluated the clinical profile, in-hospital outcomes, and effects of revascularization on the incidence of AF in elderly patients with acute MI. Results AF was documented in 100 （11.53%） patients and the incidence of new-onset AF was 6.51% during hospitalization. History of old MI and cerebrovascular events were more common in patients with AF than in those without AF （P 〈0.001, P 〈0.01, respectively）. The incidence of AF was higher in patients with non-ST elevated MI （P=0.014）, inferior wall MI （P=0.004） and cardiac function of Killip class Ⅲ or Ⅳ （P=-0.008）. Patients with AF had more complication of pneumonia （P=0.003） and longer hospital stay. Left circumflex coronary artery involvement was more common in patients with AF （compared with patients without AF, P 〈0.001）. Percutaneous coronary intervention or coronary artery bypass grafting significantly decreased the incidence of new-onset AF from 7.97% to 3.82% （P=0.017）. AF depended to heart failure, increased the in-hospital mortality. Conclusions AF is common in elderly patients with acute MI and is associated with poorer clinical outcomes. Revascularization reduces the incidence of AF and thus improves the clinical outcomes in these patients.

关键词： myocardial infarction atrial fibrillation elderly

A Novel Rice Gene, NRR Responds to Macronutrient Deficiency and Regulates Root Growth

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Molecular Plant 2012年第1期5卷 63-72页

作者： Yu-Man Zhang yong-sheng yan Li-Na Wang Kun yang Na Xiao Yun-Feng Liu Ya-Ping Fu Zong-Xiu Sun Rong-Xiang Fang Xiao-Ying Chen State Key Laboratory of Plant Genomics Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China National Plant Gene Research Center Beijing 100101China Graduate School of the Chinese Academy of Sciences Beijing 100039China Department of Ornamental Horticulture and Landscape Architecture China Agricultural UniversityBeijing 100193China Current address:School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 610054China State Key Laboratory of Rice Biology National Rice Research InstituteHangzhou 310006 China

To better understand the response of rice to nutrient stress, we have taken a systematic approach to identify rice genes that respond to deficiency of macronutrients and affect rice growth. We report here the expression and bio- logical functions of a previously uncharacterized rice gene that we have named NRR （nutrition response and root growth）. NRR is alternatively spliced, producing two 5＇-coterminal transcripts, NRRa and NRRb, encoding two proteins of 308 and 223 aa, respectively. Compared to NRRb, NRRa possesses an additional CCT domain at the C-terminus. Expression of NRR in rice seedling roots was significantly influenced by deficiency of macronutrients. Knock-down of expression of NRRa or NRRb by RNA interference resulted in enhanced rice root growth. By contrast, overexpression of NRRa in rice exhibited significantly retarded root growth. These results revealed that both NRRa and NRRb played negative regulatory roles in rice root growth. Our findings suggest that NRRa and NRRb, acting as the key components, modulate the rice root archi- tecture with the availability of macronutrients.

关键词： Nutrient stress alternative splicing root growth rice.

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真实世界银花泌炎灵片用药人群临床特征

中国中药杂志 2018年第16期43卷 3391-3396页

作者：孙锦谢雁鸣刘峘张寅张永升庄严中国中医科学院中医临床基础医学研究所北京100700 中国中医科学院西苑医院基础医学研究所北京100091 中国人民大学统计学院北京100872 中国人民解放军海军总医院北京100048

为了解真实世界银花泌炎灵片用药人群的临床特征，该研究采集2006年2月—2015年12月全国16家三级甲等医院信息系统（hospital information system，HIS）中银花泌炎灵片用药患者信息，数据规范化后，进行描述性分析。发现5 312例患者中... 详细信息

为了解真实世界银花泌炎灵片用药人群的临床特征，该研究采集2006年2月—2015年12月全国16家三级甲等医院信息系统（hospital information system，HIS）中银花泌炎灵片用药患者信息，数据规范化后，进行描述性分析。发现5 312例患者中女性（63．67％）多于男性（36．33％）。年龄中位数为49岁，18～65岁者占74．52％。入院科室主要为妇产科（28．71％）和泌尿科（28．43％）。单次剂量中位数2g，占49．55％；每日剂量中位数6g；88．80％患者疗程在7d以下。住院时间中位数为12d，7～14 d最多（41．70％）。住院费用医保支付占80．22％，住院总费用中位数为12 211．47元。患者合并良性肿瘤（27．36％）和恶性肿瘤（15．56％）占较高比例，其次是泌尿系梗阻（15．49％）、泌尿系结石（10．52％）。最常见的中医证候为：湿热内蕴证（32．46％）、肝肾亏虚证（15．33％）、脾虚湿困证（15．01％）。临床多与抗生素、中药清热剂、补益剂等合并使用。出院结局，治愈者占44．22％，好转者占51．05％。可以看出应用银花泌炎灵片的住院患者多为成年人，女性较多，多合并肿瘤、泌尿道梗阻或结石。中医证候以湿热内蕴、肝肾亏虚及脾虚湿困为主。临床多与抗生素联合应用，用法用量基本符合药品说明书。基于HIS真实世界的研究结果为银花泌炎灵片进一步规范用药提供思路和参考。

关键词：银花泌炎灵片真实世界医院信息系统/HIS 临床特征

NUMERICAL ANALYSES ON THE BRITTLE FAILURE OR ROCKBURST OF ROCK MASS INDUCED BY TUNNEL EXCAVATIONS IN VICINITY OF A FAULT

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NUMERICAL ANALYSES ON THE BRITTLE FAILURE OR ROCKBURST OF RO...

Imperative for long-term management and surveillance in Kawasaki disease

The 7th International Symposium on Rockburst and Seismicity in Mines(RaSiM7)

作者： WEN-HUA ZHENG WEI-SHEN ZHU MIN yong yong LI and yan-sheng RUAN Geotechnical and Structural Engineering Research Center Shandong University Jinan 250061 P.R.China

＜正＞The extraordinary distributions of stress and displacement were studied under the conditions of four different factors in vicinity of a *** principles were obtained to predict the occurrences of brittle failures or *** test designs of orthogonal and uniform methods were adopted in this paper to calculate sixteen engineering schemes using numerical analyses and some regular results were ***,some typical engineering cases were analysed to study the stability of the surrounding rock masses and the possibility of the occurrence of rockburst when the excavations approach a fault.

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World Journal of Clinical Cases 2025年第4期13卷 61-63页

作者： yan Pan Fu-yong Jiao Department of Pediatrics The First Affiliated Hospital of Yangtze UniversityJingzhou 434000Hubei ProvinceChina Shaanxi Kawasaki Disease Diagnosis and Treatment Center Children’s HospitalShaanxi Provincial People’s Hospital of Xi’an Jiaotong UniversityXi’an 710000Shaanxi ProvinceChina

Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery *** the effectiveness of initial treatments,such as intravenous immunoglobulin,KD patients can experience long-term cardiovascular issues,as evidenced by a recent case report of an adult who suffered a ST-segment elevation myocardial infarction due to previous KD in the World Journal of Clinical *** editorial emphasizes the critical need for long-term management and regular surveillance to prevent such *** drawing on recent research and case studies,we advocate for a structured approach to follow-up care that includes routine cardiac evaluations and preventive measures.

关键词： Kawasaki disease Long-term management Coronary artery aneurysm Surveillance Preventive care

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逆向涡流等离子体降解飞灰中二恶英的研究

浙江大学学报（工学版） 2012年第4期46卷 584-589,598页

作者：倪明江程奎余量李晓东陆胜勇严建华浙江大学能源清洁利用国家重点实验室浙江杭州310027

利用氮气逆向涡流非平衡等离子体反应器,进行医疗垃圾焚烧飞灰中二恶英的降解.考察氮气逆向涡流非平衡等离子体放电特性,从而获得反应器稳定的工作条件.在实验过程中分别测量处理后飞灰中和尾气中的二恶英质量分数,分析利用氮气逆向涡... 详细信息

利用氮气逆向涡流非平衡等离子体反应器,进行医疗垃圾焚烧飞灰中二恶英的降解.考察氮气逆向涡流非平衡等离子体放电特性,从而获得反应器稳定的工作条件.在实验过程中分别测量处理后飞灰中和尾气中的二恶英质量分数,分析利用氮气逆向涡流非平衡等离子体反应器降解飞灰中二恶英的效果,初步探索二恶英的降解机理.结果表明,切向进气体积流量是影响放电电弧特性的关键因素,增大切向进气体积流量,可以提高电弧放电的稳定性;逆向涡流等离子体对飞灰中二恶英有明确的降解作用,单位质量飞灰中PCDD/Fs总质量的平均降解率为49.6%,总毒性当量I-TEQ平均降解率为62.3%,飞灰中PCDFs比PCDDs更容易降解.

关键词：逆向涡流非平衡等离子体二恶英飞灰降解