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The nature, type, and origin of diagenetic uids and their control on the evolving porosity of the Lower Cambrian Xiaoerbulak Formation dolostone, northwestern Tarim Basin, China

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Petroleum Science 2020年第4期17卷 873-895页

作者： Pei-Xian Liu Shi-Biao Deng Ping Guan Yi-Qiu Jin Kai Wang yong-quan chen Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing100871China Research Institute of Petroleum Exploration and Development PetroChinaBeijing100083China Research Institute of Petroleum Exploration and Development Tarim Oilfield BranchPetroChinaKorla841000XinjiangChina

The study on Lower Cambrian dolostones in Tarim Basin can improve our understanding of ancient and deeply buried carbonate *** this research,diagenetic fluid characteristics and their control on porosity evolution have been revealed by studying the petrography and in situ geochemistry of different *** types of diagenetic fluids were identified:(1) Replacive dolomites were deviated from shallow burial dolomitizing fluids,which might probably be concentrated ancient seawater at early stage.(2) Fine-to-medium crystalline,planar-e diamond pore-filling dolomites(Fd1) were likely slowly and sufficiently crystallized from deep-circulating crustal hydrothermal fluids during Devonian.(3) Coarse crystalline,non-planar-a saddle pore-filling dolomites(Fd2) might rapidly and insufficiently crystallize from magmatic hydrothermal fluids during *** dolomitizing fluids did not increase the porosity,but transformed the primary pores to dissolution pores through ***-circulating crustal hydrothermal fluids significantly increased porosity in the early stages by dissolving and then slightly decreased the porosity in the late stage due to Fd1 *** hydrothermal fluids only precipitated the Fd2 dolomites and slightly decreased the *** summary,Devonian deep-circulating crustal hydrothermal fluids dominated the porosity evolution of the Lower Cambrian dolostone reservoir in the Tarim Basin.

关键词： Lower Cambrian Dolostone reservoir In situ geochemistry Diagenetic fluids Porosity evolution

Treatment for CD57-negativeγδT-cell large granular lymphocytic leukemia with pure red cell aplasia:A case report

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World Journal of Clinical Cases 2021年第26期9卷 7818-7824页

作者： Ping-Ping Xiao Xu-Yan chen Zhi-Gao Dong Jin-Mei Huang Qing-Qing Wang yong-quan chen Yi Zhang Department of Hematology and Rheumatology The Second Affiliated Hospital of Xiamen Medical CollegeXiamen 361021Fujian ProvinceChina

BACKGROUND T-cell large granular lymphocytic leukemia(T-LGLL)is a rare type of aplastic anemia with diverse clinical *** diseases are often present at the first *** describe the treatment of a patient with CD57-negativeγδT-LGLL with pure red cell aplasia(PRCA).CASE SUMMARY A 34-year-old woman with a 20-year history of anemia visited our hospital owing to severe dizziness and was *** condition was diagnosed as CD57-negativeγδT-LGLL with PRCA through bone marrow cytology,bone marrow pathology,bone marrow flow cytometry,bone marrow multiplex polymerase chain reaction combined with fluorescent fragment analysis,and other *** with prednisone,methotrexate,and subcutaneous erythropoietin did not significantly change her hemoglobin *** treatment with oral cyclophosphamide for 3 mo,her hemoglobin level increased to approximately 100 g/*** 5 mo of treatment,the patient could perform activities of daily living *** The treatment of CD57-negativeγδT-LGLL with PRCA with cyclophosphamide helps to improve prognosis.

关键词： Large granular lymphocytic leukemia Pure red cell aplasia Aplastic anemia γδT-cell Cyclophosphamide Case report

NUMERICAL MODELLING OF THE WATER AIR TWO PHASE JET INTO A PLUNGE POOL

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Journal of Hydrodynamics 1999年第3期11卷 1-5页

作者： Xu Wei lin, Wang Wei, Yang yong quan, chen Jian kang State Key Hydraulic Lab. of High Speed Flows, Sichuan University, chengdu 610065, P.R.China (Received Sep. 23, 1997)

The areated jet into a plunge pool is simulated by using a mathematical model of water air two phase flow. The equation of air mass fraction is employed together with the equations of the algebraic stresses model (ASM) of water air mixture to give the distributions of the air concentration and other flow parameters. The computational air concentration distribution is in agreement with the experimental data.

关键词： numerical modelling two phase jet

Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： Feng Zhang chenyang Zhang Linlin Wu Wei Sun Hongliang Zhang Jianhua chen yong Pei Songjiang Li Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of Micro&Nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke:a special outlook on mitochondrial delivery

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Neural Regeneration Research 2025年第8期20卷 2181-2198页

作者： Jiali chen Yiyang Li Xingping quan Jinfen chen Yan Han Li Yang Manfei Zhou Greta Seng Peng Mok Ruibing Wang yonghua Zhao Institute of Chinese Medical Sciences State Key Laboratory of Quality Research in Chinese MedicineUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmacy Hunan Provincial People’s Hospitalthe First Affiliated Hospital of Hunan Normal UniversityChangshaHunan ProvinceChina Department of Electrical and Computer Engineering University of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmaceutical Sciences Faculty of Health SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina

Ischemic stroke is a secondary cause of mortality worldwide,imposing considerable medical and economic burdens on *** vesicles,serving as natural nanocarriers for drug delivery,exhibit excellent biocompatibility in vivo and have significant advantages in the management of ischemic ***,the uncertain distribution and rapid clearance of extracellular vesicles impede their delivery *** utilizing membrane decoration or by encapsulating therapeutic cargo within extracellular vesicles,their delivery efficacy may be greatly ***,previous studies have indicated that microvesicles,a subset of large-sized extracellular vesicles,can transport mitochondria to neighboring cells,thereby aiding in the restoration of mitochondrial function post-ischemic *** extracellular vesicles have also demonstrated the capability to transfer mitochondrial components,such as proteins or deoxyribonucleic acid,or their sub-components,for extracellular vesicle-based ischemic stroke *** this review,we undertake a comparative analysis of the isolation techniques employed for extracellular vesicles and present an overview of the current dominant extracellular vesicle modification *** the complex facets of treating ischemic stroke,we also delineate various extracellular vesicle modification approaches which are suited to different facets of the treatment ***,given the burgeoning interest in mitochondrial delivery,we delved into the feasibility and existing research findings on the transportation of mitochondrial fractions or intact mitochondria through small extracellular vesicles and microvesicles to offer a fresh perspective on ischemic stroke therapy.

关键词： delivery engineering extracellular vesicles identification ischemic stroke isolation mitochondria targeting strategy therapeutic effects

聚集数据线性模型的聚集广义改进双参数估计的相对效率

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数学的实践与认识 2018年第6期48卷 131-137页

作者：周永正陈全园徐洪焱景德镇陶瓷大学信息工程学院

对于聚集数据的线性模型，提出了聚集广义改进双参数估计的概念，给出了聚集广义改进双参数估计的两种相对效率，并得到了这两种相对效率的上界．

关键词：聚集数据线性模型聚集广义改进双参数估计相对效率

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温湿度与母猪受胎率关系的研究

畜牧与兽医 2002年第11期34卷 7-8页

作者：何勇军陈权锋佛山科学技术学院动科系广东南海528231

通过对中山市某大型猪场 449头母猪第一情期受胎率的统计及其与温湿度等主要气候生态因子的相关分析表明 ,气温对母猪第一情期受胎率的影响较大 ,它们之间呈极显著的负相关关系。其中月均气温、平均最高气温、平均最低气温及高于 30℃... 详细信息

通过对中山市某大型猪场 449头母猪第一情期受胎率的统计及其与温湿度等主要气候生态因子的相关分析表明 ,气温对母猪第一情期受胎率的影响较大 ,它们之间呈极显著的负相关关系。其中月均气温、平均最高气温、平均最低气温及高于 30℃天数与母猪第一情期受胎率的相关系数分别为 - 0 8875 ,- 0 850 7、 - 0 90 84和 - 0 90 5 9,而气湿与情期受胎率的相关系数只有 - 0 2 65 7,经检验相关关系不显著 (P >0 0 5)。高温高湿的气候 ,最易使母猪第一情期受胎率下降。改善养猪的环境 ,夏季要注意防暑或调整日粮或配种时间。

关键词：湿度母猪受胎率温度

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

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Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-Qing chen yong-Qi Li Yu-Long Wang Mei-chen Liu Yun-Bo Ruan Yang Zhang Shu-Juan Liu Qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen chen Xiaolin Zeng Le Wang Wenwu Zhang Gang Li Xing cheng Peiqiang Su yong Wan Xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury