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Antibacterial activities of a novel Cu-bearing high-entropy alloy against multi-drug-resistant Acinetobacter baumannii and Staphylococcus aureus

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Rare Metals 2022年第2期41卷 570-579页

作者： En-Ze Zhou Guang-Yu Ren Yun-Ling Sun yong-qiang fan Yi Yang Ming-Yue Sun Da-Ke Xu Yi-Ping Lu Jian-Jun Wang Hua-Bing Li Fu-Hui Wang Shenyang National Laboratory for Materials Science Key Laboratory for Anisotrotropy and Texture of Materials(Ministry of Education)School of Materials Science and EngineeringNortheastern UniversityShenyang 110819China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China General Hospital of Northern Theater Command Shenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China

Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus(MRSA)are two prevalent pathogens and have developed high resistant to most ***,it is a pressing need to develop a new method to inhibit the spread of drug-resistant *** containing high-entropy alloy(HEA,Al0.4CoCr-CuFeNi)is a new kind of alloy material,which shows extensive antibacterial activity and mechanical properties in our previous *** study further develops another HEA(CoCrCuFeNi)and evaluates its resistance against gram-negative *** and Gram-positive *** antibacterial tests show that the antibacterial rate of the HEA toward both bacteria reached nearly 99%,far better than the traditional copper-bearing 304 stainless steel(304 Cu-SS).The biofilm observation shows that the HEA could not only kill the planktonic bacteria,but also effectively inhibit the formation of *** data demonstrate that CoCrCuFeNi HEA possesses effective antibacterial and antibiofilm activities,making it a potential candidate for using in hospital,food industry,and domestic kitchens.

关键词： High-entropy alloy Acinetobacter baumannii Methicillin-resistant Staphylococcus aureus(MRSA) Antibacterial activity Antibiofilm activity

Imitation Learning Based Real-time Decision-making of Microgrid Economic Dispatch Under Multiple Uncertainties

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1183-1193页

作者： Wei Dong fan Zhang Meng Li Xiaolun fang qiang Yang School of Automation Hangzhou Dianzi UniversityHangzhou 310018China College of Electrical Engineering Zhejiang UniversityHangzhou 310027China

The intermittency of renewable energy generation,variability of load demand,and stochasticity of market price bring about direct challenges to optimal energy management of *** cope with these different forms of operation un-certainties,an imitation learning based real-time decision-mak-ing solution for microgrid economic dispatch is *** this solution,the optimal dispatch trajectories obtained by solv-ing the optimal problem using historical deterministic operation patterns are demonstrated as the expert samples for imitation *** improve the generalization performance of imita-tion learning and the expressive ability of uncertain variables,a hybrid model combining the unsupervised and supervised learn-ing is *** denoising autoencoder based unsupervised learning model is adopted to enhance the feature extraction of operation ***,the long short-term memory network based supervised learning model is used to efficiently characterize the mapping between the input space composed of the extracted operation patterns and system state variables and the output space composed of the optimal dispatch *** numerical simulation results demonstrate that under vari-ous operation uncertainties,the operation cost achieved by the proposed solution is close to the minimum theoretical *** with the traditional model predictive control method and basic clone imitation learning method,the operation cost of the proposed solution is reduced by 6.3%and 2.8%,respective-ly,overa test period of three months.

关键词： Energy management imitation learning datadriven decision economic dispatch

Energy consumption optimization for edge computing-supported cellular networks based on optimal transport theory

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Science China(Information Sciences) 2024年第2期67卷 201-218页

作者： Xiangyu LV Xiaohu GE Yi ZHONG qiang LI yong XIAO School of Electronic Information and Communications Huazhong University of Science and Technology

With advancements in mobile communication technologies, there have been multiple user device(UD) connections to cellular networks. Because of changes in the spatial distribution of UDs and application requirements, the traditional offloading mechanism based on the nearest distance will result in heavy loads for some base stations(BSs). Because there is a high-order relationship between the energy consumption of the BS processing tasks and the number of computing tasks, the traditional offloading mechanism will result in high energy consumption, and UD’s offloading decision must be dynamically adjusted. The offloading decision of UDs is optimized based on detailed information about various parameters associated with a network from the standpoint of distribution. This information includes details regarding the spatial distribution of UDs,application requirements, and the offloading period of computing tasks. Based on optimal transport theory,an energy consumption optimization algorithm is suggested to lower the total amount of energy consumed by the offloading process of UDs’ computing tasks by reasonably planning the offloading BSs of the UDs in the networks. The simulation results show that the proposed offloading mechanism based on energy consumption optimization reduces the total energy consumption of the offloading process by 28.09% when compared to the traditional offloading mechanism, and the traffic managed by each BS is balanced.

关键词： optimal transport theory edge computing energy consumption reduction dynamic voltage frequency scaling

Origin of the Yueguang gold deposit in Xinhua, Hunan Province, South China: insights from fl uid inclusion and hydrogen–oxygen stable isotope analysis

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Acta Geochimica 2024年第2期43卷 235-254页

作者： Hongxin fan qiang Wang Yulong Yang Yao Tang Hao Zou College of Earth Sciences Chengdu University of TechnologyChengdu 610059China College of Earth Sciences Jilin UniversityJilin 130061China

The Yueguang gold deposit is located in Fengjia,Xinhua County,Hunan Province,South *** represents a recently discovered small-scale gold deposit situated in the southwestern region of the Jiangnan Orogenic Belt,west of the Baimashan granitic *** order to discern the characteristics of the ore-formingﬂuids,the underlying mineralization processes,and establish a foundation for the origin of the Yueguang gold depositﬂuid inclusion micro-thermometry,as well as quartz hydrogen and oxygen isotope analysis,have been carried out on samples obtained from various stages of *** hydrothermal miner-alization stages within the Yueguang gold deposit can be categorized into three stages:(i)the barren,pre-ore quartz-pyrite stage(Stage Ⅰ),the quartz-pyrite-gold stage(Stage Ⅱ),and the post-ore quartz-carbonate stage(Stage Ⅲ),with the second stage being the main mineralization ***ﬂuid inclusions identiﬁed in samples from the main min-eralization stage can predominantly be described with the NaCl–H_(2)O and CO_(2)–NaCl–H_(2)O *** inclusions display homogenization temperatures ranging from 158.8 to 334.9℃,and theﬂuid salinity ranges from 0.3%to 4.0%(wt.%NaCl equiv.).Laser Raman spectroscopy analysis of individual inclusions further reveals the presence of gas-phases such as CO_(2),CH_(4),and N_(2).Isotopic analysis indicatesδ^(18)Oﬂuid values ranging from 3.95 to 6.7‰ and δDH_(2)O values ranging from-71.9 to-55.7‰.These results indi-cate that the ore-formingﬂuid of the Yueguang gold deposit belongs to metamorphic hydrothermalﬂuids of middle-low temperature and low *** the process of ore formation,gold is transported in the form of Au(HS)2-complexes,with gold deposition being driven byﬂuid ***,the Yueguang gold deposit is categorized as an orogenic gold deposit dominated by metamorphic hydrother-malﬂ*** may become a new target for gold exploration in the Baimashan region,central Hunan Province.

关键词： Hunan province Yueguang gold deposit Fluid inclusions Hydrogen–oxygen isotopes Laser Raman Fluid immiscibility Orogenic gold deposit

Review of the research on the development and utilization of clay-type lithium resources

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Particuology 2024年第4期87卷 46-53页

作者： Ruiqi Xie Zhihui Zhao Xiong Tong Xian Xie qiang Song Peiqiang fan Faculty of Land Resource Engineering Kunming University of Science and TechnologyKunming650093China Yunnan Engineering Research Center for Metal Tailings Resource Utilization Kunming650093China

Since the demands for lithium have been in explosive growth recently and several great clay lithium resources were founded in China,the development and utilization of clay-type lithium resources become a hot *** order to provide a guidance for the concentration and extracting lithium of clay-type lithium resources,this review systematically summarized the main types and characteristics of clay-type lithium resources and the research status of lithium extraction from clay lithium ***,the flotation research status of the main mineral of clay lithium ore was also ***,we discussed the difficulties in the development and utilization of clay-type lithium ore and put forward the subsequent research *** paper can provide a guidance for the con-centration and extracting lithium of clay-type lithium resources in the future.

关键词： Clay lithium Clay mineral flotation Lithium extraction Leaching

Supplementary inferior phrenic artery embolization in the interventional treatment of hemoptysis

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Chinese Medical Journal 2009年第5期122卷 514-520页

作者： LIU Feng-yong WANG Mao-qiang fan Qing-sheng DUAN Feng WANG Zhi-jun SONG Peng Department of Interventional Radiology Clinical Division of Medicine Chinese People's Liberation Army General Hospital Beijing 100853 China

Background Transcatheter bronchial artery embolization （BAE） is widely used for the treatment of hemoptysis and the immediate success rate is high, but there are still some hemorrhage recurrences. One of the common reasons for failure of BAE is collateral branches as blood supply. The inferior phrenic artery （IPA） is one of the most common collateral branches that is scarcely reported. Our purpose was to observe manifestations of IPA supplying to hemoptysis and evaluate the efficacy and safety of IPA embolization. Methods Angiography during interventional treatment of 178 hemoptysis patients in the past 7 years confirmed that IPA hemorrhage resulted in hemoptysis in 25 patients （26-67 years old） who had： lung cancer （11 patients）, bronchiectasis （11 patients）, chronic lung inflammation （2 patients）, and pulmonary tuberculosis （1 patient）. Among the 25 patients, 7 patients had twice interventional operations within one week and 6 patients still experienced intraoperative hemoptysis after conventional embolization of the bronchial artery, the internal thoracic artery, and the intercostal artery, then had the second interventional operation immediately. The total number of cases were 191. Selective embolization of the IPA was performed using polyvinyl alcohol microspheres, gelatin sponge particles, and microcoil. The safety and clinical significance of IPA embolization were evaluated. The Pearson X2 test and Fisher＇s exact probability test were used in this study. Results Selective IPA angiography showed increased diameter of the IPA, disorganization of the branches, and varying degrees of angiogenesis. In 11 cases, contrast material was seen in vessels supplying the tumor and in the tumor. In 9 cases, contrast material had leaked into the area supplied by the IPA; in 8 cases, non-specific flake-like deposits of contrast material were seen; and in 14 cases, abnormal communication or shunt was visualized. Lesions were closely related to the pleura in 25 patients. Fiftee

关键词： hemoptysis inferior phrenic arteries angiography embolization, therapeutic

Endovascular embolization of pulmonary arteriovenous malformations

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Chinese Medical Journal 2010年第1期123卷 23-28页

作者： LIU Feng-yong WANG Mao-qiang fan Qing-sheng DUAN Feng WANG Zhi-jun SONG Peng Department of Interventional Radiology Clinical Division ofInternal Medicine Chinese People's Liberation Army GeneralHospital Beijing 100853 China

Background The major consequence of pulmonary arteriovenous malformations （PAVMs） is the direct inflow of blood from the pulmonary artery to the pulmonary vein which induces hypoxemia. Severe complications include transient ischemic attacks, paradoxical embolization in the central nervous system, massive hemoptysis or hemothorax, etc. The conventional treatment is surgical intervention. However, this can be very traumatic and dangerous. Endovascular embolization has advantages over surgery such as a faithful therapeutic effect, a low complication rate, repeatability, etc. Methods Patients （n=-23） with symptomatic PAVMs underwent endovascular embolization; 11 were males and 12 were females, with ages ranging from 6 months to 58 years. During the embolization, microcoils were applied in 6 cases and standard steel coils were used in 17 cases. Results Multiple PAVMs lesions were found in 16 cases and single PAVMs lesion was found in 7 cases. Embolotherapy was carried out 28 times for 23 patients. The success rate was 100%. The results of pulmonary arteriography after treatment showed that single lesion disappeared completely while the main abnormal vessels in multiple lesions also disappeared. The mean blood oxygen saturation increased from （78.04＋8.22）% to （95.13＋3.67）% after the procedure. A correlated groups t test showed changes in blood oxygen saturation before and after embolization （t=9.101, P 〈0.001）. Symptoms of cardiac insufficiency disappeared in 5 cases and vascular murmur in the chest disappeared in 13 cases. After embolization, mild chest pain occurred in 11 cases, small amounts of pleural effusion occurred in 5 cases, and 1 patient died 2 months later because of a pyogenic infection secondary to the pulmonary infarction. Among the 22 remaining cases, with overall follow-up ranging from 18 months to 12 years, general conditions were fine, daily lives were normal and there were no neurologic symptoms or signs, except for 3 patients with diffused PAVMs who h

关键词： pulmonary arteriovenous malformations pulmonary artery endovascular embolization pulmonary arteriography

Experimental and numerical study of hypervelocity impact damage on composite overwrapped pressure vessels

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Defence Technology（防务技术） 2024年第1期31卷 58-72页

作者： yong-Pan Duan Run-qiang Chi Bao-Jun Pang Yuan Cai Hypervelocity Impact Research Center Harbin Institute of TechnologyHarbin150080China College of Science Heilongjiang University of Science and TechnologyHarbin 150022China

Ground-based tests are important for studying hypervelocity impact(HVI)damage to spacecraft pressure vessels in the orbital debris *** analyzed the damage to composite overwrapped pressure vessels(COPVs)in the HVI tests and classified the damage into non-catastrophic damage and catastrophic *** proposed a numerical simulation method to further study non-catastrophic damage and revealed the characteristics and mechanisms of non-catastrophic damage affected by impact conditions and internal *** fragments of the catastrophically damaged COPVs were collected after the *** crack distribution and propagation process of the catastrophic ruptures of the COPVs were *** findings contribute to understanding the damage characteristics and mechanisms of COPVs by HVIs.

关键词： Orbital debris Hypervelocity impact Composite overwrapped pressure vessels Damage mechanisms

Triclosan-conjugated,Lipase-responsive Polymeric Micelles for Eradication of Staphylococcal Biofilms

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Chinese Journal of Polymer Science 2024年第6期42卷 718-728页

作者： Yan-qiang Huang Yuan-Feng Li yong Liu Lin-Qi Shi Guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance Youjiang Medical University for NationalitiesBaise533000China Translational Medicine Laboratory the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325035China Wenzhou Institute University of Chinese Academy of SciencesWenzhou325001China State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of Educationand Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin300071China

Bacterial biofilms present a significant challenge in treating drug-resistant infections,necessitating the development of innovative *** this study,we introduce triclosan-conjugated,lipase-responsive polymeric micelles designed to exploit biofilm properties and serve as a responsive drug delivery *** micelles were created using an amphiphilic block polymer synthesized via ring-opening polymerization ofε-caprolactone(CL)and triclosan-containing cyclic trimethylene carbonate(MTC-Tri).Poly(ethylene glycol)(PEG-OH)acted as the macro-initiator,resulting in micelles with a PEG shell that facilitated their penetration into bacterial *** important advantage of our micelles lies in their interaction with local bacterial lipases within *** lipases triggered rapid micelle degradation,releasing triclosan in a controlled *** liberated triclosan effectively eliminated bacteria embedded in the ***,the triclosan-conjugated micelles displayed minimal toxicity to murine fibroblasts,indicating their biocompatibility and *** finding emphasizes the potential application of these micelles in combatting drug resistance observed in bacterial *** triclosan-conjugated,lipase-responsive polymeric micelles exhibit promising characteristics for addressing drug resistance in bacterial *** harnessing biofilm properties and implementing a responsive drug delivery system,we seek to provide an effective solution in the fight against drug-resistant bacteria.

关键词： Self-assembly Polymer prodrug Ring-opening polymerization Biofilm eradication Cytotoxicity