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Information-motivation-behavioral guided nursing for stroke patients with pulmonary dysfunction:A randomized controlled trial

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World Journal of Clinical Cases 2024年第24期12卷 5549-5557页

作者： Xia Peng Hui-Qin Ni yong-mei liu Jin-Ling Zhu Yu-Ting Bai Department of Respiratory and Critical Care Medicine Yancheng First Hospital Affiliated to Nanjing University School of MedicineYancheng 224006Jiangsu ProvinceChina Department of Neurology Yancheng First Hospital Affiliated to Nanjing University School of MedicineYancheng 224006Jiangsu ProvinceChina Department of Nursing Yancheng First Hospital Affiliated to Nanjing University School of MedicineYancheng 224006Jiangsu ProvinceChina

BACKGROUND Patients with stroke frequently experience pulmonary *** To explore the effects of information-motivation-behavioral(IMB)skills modelbased nursing care on pulmonary function,blood gas indices,complication rates,and quality of life(QoL)in stroke patients with pulmonary *** We conducted a controlled study involving 120 stroke patients with pulmonary *** control group received routine care,whereas the intervention group received IMB-model-based nursing *** parameters including pulmonary function,blood gas indices,complication rates,and QoL were assessed before and after the *** Baseline data of the control and intervention groups were ***-intervention,the IMB model-based care group showed significant improvements in pulmonary function indicators,forced expiratory volume in 1 sec,forced vital capacity,and peak expiratory flow compared with the control *** gas indices,such as arterial oxygen pressure and arterial oxygen saturation,increased significantly,and arterial carbon dioxide *** decreased significantly in the IMB model-based care group compared with the control *** intervention group also had a lower complication rate(6.67%vs 23.33%)and higher QoL scores across all domains than the control *** IMB model-based nursing care significantly enhanced pulmonary function,improved blood gas indices,reduced complication rates,and improved the QoL of stroke patients with pulmonary *** research is needed to validate these results and to assess the long-term efficacy and broader applicability of the model.

关键词： Cerebrovascular accident rehabilitation Respiratory function tests Nursing methodology research Behavioral medicine Quality of life

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Exploiting quasi-one-dimensional confinement for proficient hydrogen production from formic acid at room temperature

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Journal of Energy Chemistry 2020年第10期29卷 205-213页

作者： Tao Jiang Peng Lu Meng-Jiao Xu Jian-Dong Lin yong-mei liu yong Cao He-yong He Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of ChemistryFudan UniversityShanghai 200433China

We describe herein that the quasi-one-dimensional confinement effect of functionalized nanoporous supports is particularly advantageous for boosting formic acid(FA)dehydrogenation efficiency over palladium nanoparticles(NPs).Benefiting from their unique structural merits that lead to significant lowering of the entropic barrier for FA activation,the Pd NPs interiorly located on the amino-modified MCM-41 offer the promise of more than an order of magnitude speedup of the initial activity in H2 production from FA over their exterior *** mild and additive-free conditions,ultrafine Pd NPs confined in aminomodified MCM-41 channels exhibit an initial turnover frequency as high as 46,677 h-1 and a turnover number up to 1,060,000 at 60℃.In conjunction with the enhancement and robust performance for efficient regeneration of FA via CO2 hydrogenation,the presented approach greatly contributes to the development of FA-based hydrogen storage and related technologies as viable means of enabling sustainable future energy prospects.

关键词： Confinement effect Formic acid Heterogeneous catalysis Hydrogen storage

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Synthesis and Crystal Structure of the Copper Complex {[Cu(CH_3COO)_2(bbtz)](H_2O)_2}_n

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Chinese Journal of Structural Chemistry 2005年第10期24卷 1129-1132页

作者： ZHANG yong ZHANG Yu-mei liu Xun-Gao LI Bao-Long Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry and Chemical Engineering Suzhou University Suzhou 215123 China

The new copper complex { [Cu（CH3COO）2（bbtz）]（H2O）2 }, 1 （bbtz = 1,4-bis（ 1,2,4- triazol-1-ylmethyl）benzene） was synthesized and the structure was determined by single-crystal X-ray diffraction. Crystal data： C16H22CuN6O6, monoclinic, space group P21/n, a = 12.589（5）, b = 6.455（2）, c = 12.677（5） A, β= 98.748（9）°, V= 1018.2（7） A^3, Mr = 457.95, Z = 2, Dc= 1.494 g/cm^3, F（000） = 474, μ = 1.118 mm^-1, R = 0.0463 and wR = 0.0939 for 1971 observed reflections with I 〉 2σ（I）. The crystal structure of 1 is a one-dimensional chain via the bridging flexible ligand bbtz.

关键词： crystal structure copper complex triazole ligand synthesis

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Prediction of Rolling Load, Recrystallization Kinetics, and Microstructure During Hot Strip Rolling

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Journal of Iron and Steel Research International 2007年第6期14卷 42-46页

作者： XU Yun-bo YU yong mei liu Xiang-hua WANG Guo-dong State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

The recrystallization kinetics and grain size models were developed for the C Mn and niobium containing steels to describe the metallurgical phenomenon such as softening, grain growth, and strain accumulation. Based on the recrystallization kinetics equations, the mean flow stress and the rolling load of each pass were predicted and the optimum rolling schedule was proposed for hot strip rolling. The austenite grain refinement is associated with the addition of niobium, the decrease of starting temperature of finish rolling, and the reduction of finished thickness. The mean flow stress curve with a continuous rising characteristic can be usually observed in the finish rolling of niobium containing steel, which is formed as a result of the heavy incomplete softening and strain accumulation. The predic ted rolling loads are in good agreement with the measured ones.

关键词： hot strip rolling recrystallization mean flow stress strain accumulation grain size

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Computer Model of Phase Transformation From Hot-Deformed Austenite in Niobium Microalloyed Steels

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Journal of Iron and Steel Research International 2007年第2期14卷 66-69页

作者： XU Yun-bo YU yong-mei liu Xiang-hua WANG Guo-dong State Key Lab of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

Based on thermodynamics and kinetics, a new mathematical model was developed to calculate the CCT diagrams and the transformation kinetics in low carbon niobium steels, in which the effect of deformation on the degree of supercooling was taken into account. The undercooling caused by deformation is the major reason for the increase of the starting transition temperature during continuous cooling. The critical cooling rate of bainite formation is within 2--5 ℃s for the studied niobium steels and deformation is suitable for the occurrence of pearlite. The ferrite volume fraction increases with the increase of the austenite boundary area, and decreases with the increase of the cooling rate. The calculated CCT diagrams and the volume fraction of each phase are in good agreement with the measurements.

关键词： low carbon niobium steel thermodynamics supercooling degree continuous cooling transformation computer model

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Thermodynamic Calculation of Carbide Precipitate in Niobium Microalloyed Steels

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Journal of Iron and Steel Research International 2006年第6期13卷 53-56页

作者： XU Yun-bo YU yong-mei liu Xiang-hua WANG Guo-dong State Key Lab of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

On the basis of regular solution sublattice model, thermodynamic equilibrium of austenite/carbide in Fe-Nb-C ternary system was investigated. The equilibrium volume fraction, chemical driving force of carbide precipitates and molar fraction of niobium and carbon in solution at different temperatures were evaluated respectively. The volume fraction of precipitates increases, molar fraction of niobium dissolved in austenite decreases and molar fraction of carbon increases with decreasing the niobium content. The driving force increases with the decrease of temperature, and then comes to be stable at relatively low temperatures. The predicted ratio of carbon in precipitates is in good agreement with the measured one.

关键词： microalloyed steel thermodynamic calculation phase equilibrium carbide prediction model

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T cells in pancreatic cancer stroma:Tryptophan metabolism plays an important role in immunoregulation

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World Journal of Gastroenterology 2023年第17期29卷 2701-2703页

作者： Ting Yang Qiao-Qi Li yong-mei liu Biao Yang Department of Abdominal Oncology Division of Medical OncologyCancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Division of Radiation Oncology Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

Several studies have shown that the immune system is highly regulated by tryptophan metabolism,which serves as an immunomodulatory *** indoleamine 2,3-dioxygenase 1(IDO1),as an intracellular enzyme that participates in metabolism of the essential amino acid tryptophan in the kynurenine pathway,is an independent prognostic marker for pancreatic cancer(PC).First,overexpression of IDO1 inhibits the maturation of dendritic cells and T-cell proliferation in the liver and ***,the high expression of kynurenine induces and activates the aryl hydrocarbon receptor,resulting in upregulated programmed cell death protein 1 ***,the induction of IDO1 can lead to loss of the T helper 17 cell/regulatory T cell balance,mediated by the proximal tryptophan catabolite from IDO *** our study,we found that overexpression of IDO1 upregulated CD8+T cells and reduced natural killer T cells in pancreatic carcinoma in ***,it may be essential to pay more attention to tryptophan metabolism in patients,especially those who are tolerant to immunotherapy for PC.

关键词： Immunosuppression Pancreatic cancer stroma T cell Tryptophan metabolism Xxx

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Experimental research on oxidation of phenol by activated persulfate

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Journal of Coal Science & Engineering(China) 2013年第4期19卷 560-565页

作者： Zhuan-Nian liu Kun-Kun ZHANG yong-mei liu College of Geology and Environment Xi'an Universi(y of Science and Technology Xi'an 710054 China

In this paper, the optimum process parameters were obtained through treating phenol of simulated semi-coking wastewater using heat, Fe2＋, Fe^0 and semi-coke to catalyze persulfate. The results of phenol decomposition using PS catalyzed by heating, Fe2＋, Fe^0 and semi-coke were compared for selecting a better activating way. The article investigated the effects of temperature, catalyzer dosage, pH value and reaction time. The experiment showed the four methods can all catalyzed the process. Under the experimental conditions of heating, Fe2＋, Fe^0 and semi-coke degradation rate could reach to 20.7%, 75.1%, 94.5% and 40.0%, respectively. On this basis, this study established an Lt6（45） table to analyze the main influencing factors in semi-coke/Fe^0 catalyzing system. Under the optimum conditions, the degradation rate of Phenol reached to 93.6%. However, the PS dosage was reduced by 14.4%.

关键词： persulfate (PS) catalytic oxidation phenol semi-coke semi-coking wastewater

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Significant benefits of osimertinib in treating acquired resistance to first-generation EGFR-TKIs in lung squamous cell cancer: A case report

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World Journal of Clinical Cases 2019年第10期7卷 1221-1229页

作者： Yan Zhang Hui-Min Chen yong-mei liu Feng Peng Min Yu Wei-Ya Wang Heng Xu yong-Sheng Wang You Lu Department of Thoracic Oncology Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Pathology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Precision Medicine Center State Key Laboratory of BiotherapyPrecision Medicine Key Laboratory of Sichuan ProvinceWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Lung squamous cell cancer(LSCC)rarely harbors epidermal growth factor receptor(EGFR)mutations,even much rarer for acquired T790M *** clinical trials of AURA series illustrated that non-small cell lung cancer(NSCLC)with EGFR T790M mutation can benefit from osimertinib,only five LSCC patients were enrolled in total;moreover,the efficacy for LSCC was not shown in the ***,the response of LSCC to osimertinib is still unclear to *** SUMMARY We report an LSCC case with T790M-related acquired resistance after treatments with first-generation EGFR-tyrosine kinase inhibitors(EGFR-TKIs)and benefited from osimertinib significantly.A 63-year-old Chinese man was diagnosed with stage IV(cT2N2M1b)LSCC harboring an EGFR exon 19-deletion *** disease progression after gefitinib and multi-line chemotherapy,rebiopsy was *** testing of EGFR by amplification refractory mutation system-polymerase chain reaction detected the exon 19-deletion without T790M ***,the patient was given erlotinib,but progression developed only 3 mo *** the frozen re-biopsy tissue was tested by next-generation sequencing(NGS),which detected an EGFR T790M ***,he was very weak with symptoms of dysphagia and ***,osimertinib was started,leading to alleviation from the *** months later,normal deglutition was restored and partial response was ***,the patient achieved an overall survival time period of 29 *** Our findings highlight that EGFR T790M mutation may also be an important acquired drug resistance mechanism for LSCC and offer direct evidence of the efficacy of osimertinib in LSCC with T790M *** and better preservation conditions may contribute to higher sensitivity of EGFR T790M detection.

关键词： Lung squamous cell cancer Lung cancer Epidermal growth factor receptor mutation T790M Osimertinib Tyrosine kinase inhibitor Targeted therapy Case report

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Effect of MgO-Cr_(2)O_(3) and Mg0-MgAl_(2)0_(4)-based refractories on refractory-steel interface reaction and cleanliness of pipeline steel

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Journal of Iron and Steel Research International 2024年第4期31卷 849-860页

作者： Guang-mei Yang Cheng Yuan Chang liu Qiang Wang Guang-qiang Li yong-shun Zou Ao Huang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina

The interaction of MgO-MgAl_(2)O_(4)-based and MgO-Cr_(2)O_(3)-based refractories with X70 molten steel was studied by immersion experiments at 1560℃.The effects of immersion time(30 and 60 min)on the contents of total oxygen(TO),Al,Nb,Si,Mn,and Cr as well as the composition,number density,and size distribution of inclusions in the molten steel were *** influence of the penetration and erosion degree of the molten steel to the refractory on the steel-refractory interface layer was *** results show that,at 1560℃,the MgO-MgAl_(2)O_(4)-based refractory can better control the contents of TO and the composition of molten steel compared with the MgO-Cr_(2)O_(3)-based *** TO content is only 16×10^(-4) wt.%in the molten steel after reacted with the Mg0-MgAl_(2)O_(4)-based refractory at the end point of refining,4 accounting for 11.5%of that reacted with the MgO-Cr_(2)O_(3)-based refractory(139×10^(-4) wt.%).The number density of inclusions is only 14 mm^(-2),and the average size ofinclusions is only 1.31μm,with thelargest proportion of inclusions in 1-2μm(70%).The Al_(2)O_(3)-MnS-CaO complex inclusions in the original steel changed to complex inclusions dominated by Cr-Nb-Mn-S-O and ***_(2)O_(3),corresponding to the MgO-Cr_(2)O_(3)-based and MgO-MgAl_(2)O_(4)-based refractories,*** ***_(2)O_(3) layer was formed at the reaction interface between MgO-MgAl_(2)O_(4)-based refractory and molten steel,which is helpful to restrict the erosion of refractories and the pollution of molten *** damage mechanism of the MgO-Cr_(2)O_(3)-based refractory is mainly permeation and chemical reaction,while the damage of the MgO-MgAl_(2)O_(4)-based refractory is mainlyscouring erosion.

关键词： MgO-Cr_(2)O_(3)-based refractory MgO-MgAl O_(4)-based refractory Nonmetallic inclusion Erosion interface layer Steel penetration

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