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Effect of solution treatment and artificial aging on microstructure and mechanical properties of Al-Cu alloy

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Transactions of Nonferrous Metals Society of China 2013年第3期23卷 631-635页

作者： Jae-ho JANG Dae-Geun NAM yong-ho park Ik-Min park Korea Institute of Industrial Technology Busan 618-230Korea School of Material Science and Engineering Pus an National UniversityBusan 609-735Korea

In order to achieve good mechanical properties of Al-Cu alloys such as high strength and good toughness,precipitation hardening and artificial aging treatment were *** defined by the T6 heat treatment,the standard artificial aging treatment for Al-Cu alloy followed heat treatments of solution treatment at 510-530 ℃ for 2 h,quenching in water at 60 ℃ and then artificial aging at 160-190 ℃ for 2-8 *** effects of solution treatment and artificial aging on the microstructure and mechanical properties of Al-Cu alloy were studied by optical microscopy（OM）,scanning electron microscopy（SEM）,energy dispersive X-ray spectroscopy（EDS）,transmission electron microscopy（TEM） and tensile *** results of solution treatment indicate that the mechanical properties of Al-Cu alloy increase and then decrease with the increase of solution *** is because the residual phases dissolve gradually into the matrix,and the fraction of the precipitation and the size of the re-crystallized grain *** to the solution temperature,the solution holding time has less effect on the microstructure and the mechanical properties of Al-Cu *** artificial aging treatments were conducted at 160-180 ℃ for 2-8 *** results show that the ultimate tensile strength can be obtained at 180 ℃ for 8 *** tensile strength increased with increasing time or *** strength was found as the same as the ultimate tensile strength result.

关键词： Al-Cu alloy solid solution treatment artificial aging microstructure mechanical property

Highly Active Enzymes Produced by the Microbes from Biodiversity for Feed Enzymes

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Highly Active Enzymes Produced by the Microbes from Biodiver...

Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease:pathologic roles and therapeutic implications

首届饲料酶制剂应用技术论坛暨饲料酶制剂大会

作者： ho-yong park Korea Research Institute of Bioscience and Biotechnology/Insect Biotech Co.Ltd.

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Translational Neurodegeneration 2021年第4期10卷 643-665页

作者： Hyeon soo Kim Sujin Kim Soo Jung Shin yong ho park Yunkwon Nam Chae won Kim Kang won Lee Sung-Min Kim In Duk Jung Hyun Duk Yang Yeong-Min park Minho Moon Department of Biochemistry College of MedicineKonyang UniversityDaejeon 35365Republic of Korea Research Institute for Dementia Science Konyang UniversityDaejeon 35365Republic of Korea Dandi Bioscience Inc 6th Floor of Real Company Building66Achasan-roSungdong-guSeoulRepublic of Korea Harvard Neurology Clinic 294 Gwanggyojungang-roSuji-guYongin 16943Republic of Korea Department of Immunology School of MedicineKonkuk University268ChungwondaeroChungju-siChungcheongbuk-doRepublic of Korea

Alzheimer's disease(AD)is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive *** in the development of therapeutics targeting amyloid-β(Aβ)and tau;principal proteins inducing pathology in AD,suggest a paradigm shift towards the development of new therapeutic *** gram-negative bacteria and lipopolysaccharides(LPS)are attractive new targets for AD ***,an altered distribution of gram-negative bacteria and their LPS has been reported in AD ***,gram-negative bacteria and their LPS have been shown to affect a variety of AD-related pathologies,such as Aβ homeostasis,tau pathology,neuroinflammation,and ***,therapeutic approaches targeting gram-negative bacteria or gram-negative bacterial molecules have significantly alleviated AD-related pathology and cognitive *** multiple evidence showing that the gram-negative bacteria and their LPS play a crucial role in AD pathogenesis,the pathogenic mechanisms of gram-negative bacteria and their LPS have not been ***,we summarize the roles and pathomechanisms of gram-negative bacteria and LPS in ***,we discuss the possibility of using gram-negative bacteria and gram-negative bacterial molecules as novel therapeutic targets and new pathological characteristics for AD.

关键词： Alzheimer's disease Gram-negative bacteria Lipopolysaccharide Exotoxin Amyloid beta Tau

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白头翁提取液对植物的化感作用

安徽农业科学 2007年第13期35卷 3808-3809,3814页

作者：朴仁哲赵洪颜金大成崔英顺田官荣 ho yong-park 长白山生物功能因子省部共建教育部重点实验室延边大学吉林延吉133002 韩国生命工学研究院昆虫资源研究室

以白头翁的正丁醇、氯仿提取液为供试材料,选用5种受体植物,通过发芽和生长试验以及茎叶处理试验和叶绿素的测定,研究了白头翁提取液对植物的化感作用。结果表明,白头翁正丁醇提取液对萝卜、稗草和马唐的根系生长抑制作用显著;白头翁氯... 详细信息

以白头翁的正丁醇、氯仿提取液为供试材料,选用5种受体植物,通过发芽和生长试验以及茎叶处理试验和叶绿素的测定,研究了白头翁提取液对植物的化感作用。结果表明,白头翁正丁醇提取液对萝卜、稗草和马唐的根系生长抑制作用显著;白头翁氯仿提取液对萝卜、莴苣、稗草和马唐的株高和根系抑制作用显著,在茎叶处理试验中,白头翁氯仿提取液对莴苣和萝卜的株高和鲜重抑制率较高;2种提取液在1000 mg/L浓度下对黄瓜的叶绿素a、b和类胡萝卜素形成抑制作用显著。

关键词：白头翁提取液化感作用

Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun Lee yong Nam Ahn Seongjoon So Chanwoo park Jong-Seong Bae Taehyun park Il Tae Kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Artificial layer Dielectric constant Zn metal anode Zinc aqueous battery

Extended X-ray absorption fine structure (EXAFS) of FAPbI_(3) for understanding local structure-stability relation in perovskite solar cells

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Journal of Energy Chemistry 2022年第4期31卷 549-554页

作者： Dong-ho Kang yong-Jun park Yun-Sung Jeon Nam-Gyu park School of Chemical Engineering and Center for Antibonding Regulated Crystals Sungkyunkwan UniversitySuwon 16419Korea

Perovskite solar cells (PSCs) employing formamidinium lead iodide (FAPbI_(3)) have shown high ***,operational stability has been issued due to phase instability of α phase FAPbI_(3) at ambient *** precursors in the perovskite precursor solution has been proposed to improve not only power conversion efficiency (PCE) but also device ***,there is a controversial issue on the beneficial effect on PCE and/or stability between excess FAI and excess PbI_(2).We report here extended X-ray absorption fine structure (EXAFS) of FAPbI_(3) to study local structural change and explain the effect of excess precursors on photovoltaic performance and *** films prepared from the precursor solution with excess PbI_(2)shows better stability than those from the one with excess FAI,despite similar PCE.A rapid phase transition from α phase to non-perovskite δ phase is observed from the perovskite film formed by excess ***,the (Pb-I) bond distance evaluated by the Pb L_(III)-edge EXAFS study is increased by excess FAI,which is responsible for the phase transition and poor device *** work can provide important insight into local structure-stability relation in the FAPbI_(3)-based PSCs.

关键词： Extended X-ray absorption fine structure EXAFS Excess precursor Local structure Stability Perovskite solar cells

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Neural Regeneration Research 2017年第10期12卷 1640-1647页

作者： Jisu hong Bo-yong park Hwan-ho Cho Hyunjin park Department of Electronic Electrical and Computer EngineeringSungkyunkwan UniversitySuwonKorea Center for Neuroscience Imaging Research(CNIR) Institute for Basic ScienceSuwonKorea School of Electronic and Electrical Engineering Sungkyunkwan UniversitySuwonKorea

Attention deficit and hyperactivity disorder（ADHD） is a disorder characterized by behavioral symptoms including hyperactivity/impulsivity among children,adolescents,and *** ADHD related symptoms are influenced by the complex interaction of brain networks which were under *** explored age-related brain network differences between ADHD patients and typically developing（TD） subjects using resting state f MRI（rs-f MRI） for three age groups of children,adolescents,and *** collected rs-f MRI data from 184 individuals（27 ADHD children and 31 TD children;32 ADHD adolescents and 32 TD adolescents;and 31 ADHD adults and 31 TD adults）.The Brainnetome Atlas was used to define nodes in the network *** compared three age groups of ADHD and TD subjects to identify the distinct regions that could explain age-related brain network differences based on degree centrality,a well-known measure of nodal *** left middle temporal gyrus showed significant interaction effects between disease status（i.e.,ADHD or TD） and age（i.e.,child,adolescent,or adult）（P 0.001）.Additional regions were identified at a relaxed threshold（P 0.05）.Many of the identified regions（the left inferior frontal gyrus,the left middle temporal gyrus,and the left insular gyrus） were related to cognitive *** results of our study suggest that aberrant development in cognitive brain regions might be associated with age-related brain network changes in ADHD *** findings contribute to better understand how brain function influences the symptoms of ADHD.

关键词： nerve regeneration attention deficit and hyperactivity disorder cognitive function connectivity resting-state f MRI Brainnetome Atlas whole brain analysis disease-aging interaction effect neuroscience neural regeneration

Inhibitory Effect of the Extract of Phellodendron amurense Ruprecht Root on Collagen-Induced Arthritis in Mice

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Chinese Journal of Integrative Medicine 2017年第10期23卷 755-762页

作者： Hyo Won Jung Kyung-ho Kim yong-Ki park Department of Herbology College of Korean Medicine Dongguk University Gyeongju (740-814) Republic of Korea Korean Medicine Research and Development Center Dongguk University Gyeongju (740-814) Republic of Korea Department of Acupuncture College of Korean Medicine Dongguk University Gyeongju (740-814) Republic of Korea

Objective： To investigate whether the dried root of Phellodendron amurense Ruprecht（Phellodendri cortex; PC） extract improves arthritic symptoms through anti-inflammatory and immune-modulatory effects in collagen-induced arthritis in mice. Methods： Rheumatoid arthritis（RA） was induced in male DBA/1 mice by immunization with type Ⅱ collagen（ColⅡ）. CIA mice were divided into 5 groups（n=10 per a group） with normal, CIA control, PC extract（50 mg/kg and 100 mg/kg）-treated, and meloxicam（50 mg/kg）-treated as the reference drug. The PC extract or meloxicam were administered orally in CIA mice once a day for 14 days after arthritis induction. Arthritic score, levels of anti-ColⅡ IgG2a antibody, prostaglandin E2（PGE2）, tumor necrosis factor（TNF）-α, and interleukin（IL）-17 in the sera of CIA mice were measured. Histopathological changes in the ankle joints of CIA mice were also analyzed by staining with hematoxylin and eosin（H and E）, safranin-O and immunohistochemistry using anti-TNF-α and anti-IL-17 antibodies. Results： The arthritic score was increased in CIA mice in a time-dependent manner, as were the serum levels of anti-ColⅡ IgG2a antibody, PGE2, TNF-α, and IL-17. however, the oral administration of PC extract at 50 and 100 mg/kg in CIA mice significantly decreased the arthritic scores, and the serum levels of anti-ColⅡ IgG2a, PGE2, TNF-α, and IL-17 compared with those in the CIA group（P〈0.05 or P〈0.01）. Furthermore, histopathological improvement of the joint architecture in CIA mice was observed after administration of PC extract. PC extract also significantly inhibited the expression of TNF-α and IL-17 in the joints of CIA mice by suppressing the expression of their m RNA and proteins. Conclusion： PC extract may improve the pathological progression of RA through the inhibition of joint destruction by synovial inflammation and immune-stimulation, therefore, it would be a potential anti-arthritic agent in RA.

关键词： Phellodendron amurense Phellodendri cortex collagen-induced arthritis anti-arthritic effect

Predicting tumor response after preoperative chemoradiation using clinical parameters in rectal cancer

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World Journal of Gastroenterology 2011年第48期17卷 5310-5316页

作者： Chan ho park Hee Cheol Kim yong Beom Cho Seong Hyeon Yun Woo yong Lee Young Suk park Doo ho Choi ho-Kyung Chun Departmentof Surgery Samsung Medical Center Sungkyunkwan Univer-sity School of Medicine Irwon-dong 50 Gangnam-gu Seoul135-710 South Korea Division of Hematology-Oncology Depart-ment of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Irwon-dong 50 Gangnam-guSeoul 135-710 South Korea Department of Radiation Oncology SamsungMedical Center Sungkyunkwan University School of MedicineIrwon-dong 50 Gangnam-gu Seoul 135-710 South Korea

AIM: To evaluate the clinical parameters and identify a better method of predicting pathological complete response (pCR). METhoDS: We enrolled 249 patients from a database of 544 consecutive rectal cancer patients who underwent surgical resection after preoperative chemoradiation therapy (PCRT). A retrospective review of morphological characteristics was then performed to collect data regarding rectal examination findings. A scoring model to predict pCR was then created. To validate the ability of the scoring model to predict complete ***: Seventy patients (12.9%) achieved a pCR. A multivariate analysis found that pre-CRT movability (P = 0.024), post-CRT size (P = 0.018), post-CRT morphology (P = 0.023), and gross change (P = 0.009) were independent predictors of pCR. The accuracy of the scoring model was 76.8% for predicting pCR with the threshold set at 4.5. In the validation set, the accuracy was 86.7%. CONCLUSION: Gross changes and morphological findings are important predictors of pathological response. Accordingly, PCRT response is best predicted by a combination of clinical, laboratory and metabolic information.

关键词： Rectal cancer Preoperative chemoradiotherapy Downstaging Tumor regression Validation