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Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis?

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World Journal of Gastroenterology 2008年第15期14卷 2401-2405页

作者： Yeon soo kim Byung Seok Lee Seok Hyun kim Jae Kyu Seong Hyun yong Jeong Heon Young Lee Departments of Internal Medicine Daejeon St. Mary's Hospital Medical College of the Catholic University of Korea Korea Department of Internal Medicine Chungnam National University Hospital Daejeon 301721 Korea

AIM: To investigate the correlation between the changes of pancreatic enzyme, the biochemical markers and the clinical results according to the Balthazar computer tomography (CT) grade. METHODS: Between July 2004 and July 2005, we reviewed the charts of 119 patients who were admitted to our hospital with acute pancreatitis. RESULTS: Eighty-three patients (69.7%) were male, and the mean age of the patients was 57 ± 15.7 years. The biliary pancreatitis patients had an older mean age. Forty-nine patients (41.1%) had biliary pancreatitis and forty-six (38.6%) had alcoholic pancreatitis. Group 3 patients had a longer duration of pain (2.51 ± 1.16 vs 3.17 ± 1.30 vs 6.56 ± 6.13, P < 0.001), a longer period of fasting (7.49 ± 4.65 vs 10.65 ± 5.54 vs 21.88 ± 13.81, P < 0.001) and a longer hospital stay (9.17 ± 5.34 vs 14.63 ± 8.65 vs 24.47 ± 15.52, P < 0.001) than the other groups. On the univariate analysis, the factors that affected the radiological grade were the leukocyte count at admission (P = 0.048), the hemoglobin (P = 0.016) and total bilirubin concentrations (P = 0.023), serum lipase (P = 0.009), the APACH Ⅱ scores at admission (P = 0.017), the APACH Ⅱ scores after 24 h (P = 0.031), the C-reactive protein (CRP) titer (P = 0.0001) and the follow up CRP titer (P = 0.003). But the CRP level (P = 0.001) and follow up CRP titer (P = 0.004) were only correlated with the radiological grade on multivariate analysis. According to the ROC curve, when we set the CRP cut off value at 83 mg/L, the likelihoodratio for a positive test was 3.84 and the likelihood ratio for a negative test was 0.26 in group 3. CONCLUSION: In conclusion, our study suggests that the CRP with the radiological severity may be used to estimate the severity of acute pancreatitis.

关键词： Acute pancreatitis Computed tomography C-reactive protein

Accurate Multi-Site Daily-Ahead Multi-Step PM_(2.5)Concentrations Forecasting Using Space-Shared CNN-LSTM

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Computers, Materials & Continua 2022年第3期70卷 5143-5160页

作者： Xiaorui Shao Chang soo kim Department of Information Systems Pukyong National UniversityBusan608737Korea

Accurate multi-step PM_(2.5)(particulate matter with diameters≤2.5 um)concentration prediction is critical for humankinds’health and air populationmanagement because it could provide strong evidence for ***,it is very challenging due to its randomness and *** paper proposed a novel method based on convolutional neural network(CNN)and long-short-term memory(LSTM)with a space-shared mechanism,named space-shared CNN-LSTM(SCNN-LSTM)for multi-site dailyahead multi-step PM_(2.5)forecasting with self-historical *** proposed SCNN-LSTM contains multi-channel inputs,each channel corresponding to one-site historical PM_(2.5)concentration *** which,CNN and LSTM are used to extract each site’s rich hidden feature representations in a stack ***,CNN is to extract the hidden short-time gap PM_(2.5)concentration patterns;LSTM is to mine the hidden features with long-time *** channel extracted features aremerged as the comprehensive features for future multi-step PM_(2.5)concentration ***,the space-shared mechanism is implemented by multi-loss functions to achieve space information ***,the final features are the fusion of short-time gap,long-time dependency,and space information,which enables forecasting more *** validate the proposed method’s effectiveness,the authors designed,trained,and compared it with various leading methods in terms of RMSE,MAE,MAPE,and R^(2)on four real-word PM_(2.5)data sets in Seoul,South *** massive experiments proved that the proposed method could accurately forecast multi-site multi-step PM_(2.5)concentration only using self-historical PM_(2.5)concentration time series and running ***,the proposed method obtained averaged RMSE of 8.05,MAE of 5.04,MAPE of 23.96%,and R^(2)of 0.7 for four-site daily ahead 10-hourPM_(2.5)concentration forecasting.

关键词： PM_(2.5)forecasting CNN-LSTM air quality management multi-site multi-step forecasting

Game Outlier Behavior Detection System Based on Dynamic Time Warp Algorithm

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Computer Modeling in Engineering & Sciences 2022年第4期131卷 219-237页

作者： Shinjin Kang soo Kyun kim School of Games Hongik UniversitySejong30016Korea Department of Computer Engineering Jeju National UniversityJeju63243Korea

This paper proposes a methodology for using multi-modal data in gameplay to detect outlier *** proposedmethodology collects,synchronizes,and quantifies time-series data fromwebcams,mouses,and *** expressions are varied on a one-dimensional pleasure axis,and changes in expression in the mouth and eye areas are detected ***,the keyboard and mouse input frequencies are tracked to determine the interaction intensity of ***,we apply a dynamic time warp algorithm to detect outlier *** detected outlier behavior graph patterns were the play patterns that the game designer did not intend or play patterns that differed greatly from those of other *** outlier patterns can provide game designers with feedback on the actual play experiences of users of the *** results can be applied to the game industry as game user experience analysis,enabling a quantitative evaluation of the excitement of a game.

关键词： Facial expression recognition webcam behavior analysis affective computing

Design of Learning Media in Mixed Reality for Lao Education

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Computers, Materials & Continua 2020年第7期64卷 161-180页

作者： Kalaphath Kounlaxay soo Kyun kim Department of Game Engineering Pai Chai UniversityDaejeon35345Korea Department of Computer Engineering Jeju National UniversityJeju63243Korea

To improve and develop education systems,the communication between instructors and learners in a class during the learning process is of utmost *** the presentations of 3D models using mixed reality(MR)technology can be used to avoid misinterpretations of oral and 2D model *** an independent concept and MR applications,MR combines the excellent of each virtual reality(VR)and augmented reality(AR).This work aims to present the descriptions of MR systems,which include its devices,applications,and literature reviews and proposes computer vision tracking using the AR Toolkit Tracking *** focus of this work will be on creating 3D models and implementing in Unity 3D using the Vuforia SDK platform to develop VR and AR applications for architectural presentations.

关键词： Mixed reality virtual reality augmented reality Vuforia head-mounted displays.

Outlier Behavior Detection for Indoor Environment Based on t-SNE Clustering

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Computers, Materials & Continua 2021年第9期68卷 3725-3736页

作者： Shinjin Kang soo Kyun kim School of Games Hongik UniversitySejong30016Korea Department of Computer Engineering Jeju National UniversityJeju63243Korea

In this study,we propose a low-cost system that can detect the space outlier utilization of residents in an indoor *** focus on the users’app usage to analyze unusual behavior,especially in indoor *** is reflected in the behavioral analysis in that the frequency of using smartphones in personal spaces has recently *** system facilitates autonomous data collection from mobile app logs and Google app servers and generates a high-dimensional dataset that can detect outlier *** density-based spatial clustering of applications with noise(DBSCAN)algorithm was applied for effective singular movement *** analyze high-level mobile phone usage,the t-distributed stochastic neighbor embedding(t-SNE)algorithm was *** two clustering algorithms can effectively detect outlier behaviors in terms of movement and app usage in indoor *** experimental results showed that our system enables effective spatial behavioral analysis at a low cost when applied to logs collected in actual living ***,large volumes of data required for outlier detection can be easily *** system can automatically detect the unusual behavior of a user in an indoor *** particular,this study aims to reflect the recent trend of the increasing use of smartphones in indoor spaces to the behavioral analysis.

关键词： Outlier detection trajectory clustering behavior analysis app data smartphone

Complete characterization of ultrafast optical fields by phase-preserving nonlinear autocorrelation

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Light(Science & Applications) 2022年第10期11卷 2451-2462页

作者： Alexander Gliserin soo Hoon Chew Seungchul kim Dong Eon kim Department of Optics and Mechatronics Engineering College of Nanoscience and NanotechnologyPusan National University2 Busandaehak-ro 63beon-gilBusan 46241South Korea Department of Cogno Mechatronics Engineering College of Nanoscience and NanotechnologyPusan National University2 Busandaehak-ro 63beon-gilBusan 46241South Korea Max Planck Center for Attosecond Science Max Planck POSTECH/Korea Research Initiative77 Cheongam-roPohang 37673South Korea Department of Physics Center for Attosecond Science and TechnologyPohang University of Science and Technology77 Cheongam-roPohang 37673South Korea

Nonlinear autocorrelation was one of the earliest and simplest tools for obtaining partial temporal information about an ultrashort optical pulse by gating it with ***,since the spectral phase is lost in a conventional autocorrelation measurement,it is insufficient for a full characterization of an ultrafast electric field,requiring additional spectral information for phase ***,we show that introducing an intensity asymmetry into a conventional nonlinear interferometric autocorrelation preserves some spectral phase information within the autocorrelation signal,which enables the full reconstruction of the original electric field,including the direction of time,using only a spectrally integrating *** call this technique Phase-Enabled Nonlinear Gating with Unbalanced Intensity(PENGUIN).It can be applied to almost any existing nonlinear interferometric autocorrelator,making it capable of complete optical field characterization and thus providing an inexpensive and less complex alternative to methods relying on spectral measurements,such as frequency-resolved optical gating(FROG)or spectral phase interferometry for direct electric-field reconstruction(SPIDER).More importantly,PENGUIN allows the precise characterization of ultrafast fields in non-radiative(e.g.,plasmonic)nonlinear optical interactions where spectral information is *** demonstrate this novel technique through simulations and experimentally by measuring the electric field of~6-fs laser pulses from a Ti:sapphire *** results are validated by comparison with the well-established FROG method.

关键词： autocorrelation nonlinear characterization

Dynamic PIV Measurement of a Compressible Flow Issuing from an Airbag Inflator Nozzle

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Journal of Thermal Science 2006年第4期15卷 377-381页

作者： SangJoonLee YoungGilJang Seokkim Chang soo kim Department of Mechanical Engineering POSTECHSan 31Hyoja DongPohang790-784Korea Safety System R&D Department Hyundai MOBIS80-10Mabook-RiGuseong-EupYongin-ShiGyunggi-Do449-910Korea

Among many equipment for passenger safety, the air bag system is the most fundamental and effective device for an automobile. The inflator housing is a main part of the curtain-type air bag system, which supplies high-pressure gases in pumping up the air bag-curtain which is increasingly being adapted in deluxe cars for protecting passengers from the danger of side clash. However, flow information on the inflator housing is very limited. In this study, we measure the instantaneous velocity fields of a high-speed compressible flow issuing from the exit nozzle of an inflator housing using a dynamic PIV system. From the velocity field data measured at a high frame-rate, we evaluate the variation of the mass flow rate with time. The dynamic PIV system consists of a high-repetition Nd：YLF laser, a high-speed CMOS camera, and a delay generator. The flow images are taken at 4000 fps with synchronization of the trigger signal for inflator ignition. From the instantaneous velocity field data of flow ejecting from the airbag inflator housing at the initial stage, we can see a flow pattern of broken shock wave front and its downward propagation. The flow ejecting from the inflator housing is found to have very high velocity fluctuations, with the maximum velocity at about 700 m/s. The time duration of the high-speed flow is very short, and there is no perceptible flow after 100 ms.

关键词： Airbag inflator PIV automobile.

Effect of natural extract eye drops in dry eye disease rats

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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1023-1030页

作者： soo Youn Choi Youngsub Eom Jee yong kim Dong Hoon Jang Jong Suk Song Hyo Myung kim Department of Ophthalmology Korea University College of MedicineSeoul 02841Republic of Korea BGN World Tower Eye Clinic Seoul 05551Republic of Korea Department of Ophthalmology Korea University Ansan HospitalKorea University College of MedicineGyeonggi-do 15355Republic of Korea Medical O Co. Ltd.Seoul 06025Republic of Korea

AIM:To investigate the therapeutic effect of natural extract eye drops containing bee venom,musk,and deer antlers in dry eye disease(DED)animal ***:Scopolamine-injected DED rats and lacrimal gland-excised rats were allocated into control,saline,and natural extract groups respectively and a normal group(lacrimal gland excision was not performed)in lacrimal gland-excised *** eye drop instillation 4 times a day for 5 d,corneal fluorescein staining(CFS)scores,tear MUC5AC levels,and tear lactic dehydrogenase(LDH)levels were ***:In scopolamine-injected rats,the natural extract-treated group had significantly lower CFS scores(1.7±0.5,4.7±1.4,3.8±1.9,P=0.006)and tear LDH levels(0.10±0.01,0.19±0.01,0.16±0.08 OD,P=0.014)but higher tear MUC5AC levels(12.9±3.7,7.9±2.0,9.7±3.6 ng/m L,P=0.041)compared with the control and saline-treated *** were no significant differences between the control and saline-treated *** lacrimal gland-excised rats,the natural extract-treated group also had lower CFS scores(4.3±1.2,11.5±2.3,9.0±1.9,P<0.001,P=0.001)and tear LDH levels(0.30±0.08,0.48±0.12,0.39±0.05 OD,P<0.05)but higher tear volume(4.3±0.9,1.9±0.7,2.8±1.1 mm,P=0.005,P=0.124)and tear MUC5 AC levels(8.2±2.0,2.9±1.2,5.4±2.2 ng/m L,P<0.001,P=0.047)compared with the control and saline-treated *** were no significant differences in the CFS scores,tear MUC5AC level,and tear LDH level between the normal and natural extracttreated ***:The natural extract consisting of bee venom,musk,and deer antlers may have effectiveness in DED treatment by restoring the damaged ocular surface,increasing tear volume,and recovering the tear mucin layer in DED rats.

关键词： bee venom musk deer antler natural extract dry eye disease rat

Effect of itopride, a new prokinetic, in patients with mild GERD: A pilot study

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World Journal of Gastroenterology 2005年第27期11卷 4210-4214页

作者： yong Sung kim Tae Hyeon kim Chang soo Choi Young Woo Shon Sang Wook kim Geom Seog Seo yong Ho Nah Myung Gyu Choi Suck Chei Choi Department of Internal Medicine

AIM： Itopride is a newly developed prokinetic agent, which enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions. The importance of esophageal motor dysfunction in the pathogenesis of gastro-esophageal reflux disease （GERD） makes it interesting to examine the effect of itopride on esophageal acid ***： The effect of itopride on esophageal acid reflux variables for 24 h was studied in 26 patients with GERD symptoms, pre-entry total acid exposure time （pH〈4） of more than 5% and mild esophagitis （SavaryMiller grades I, II） proven by endoscopy. Ambulatory 24hpH-metry and symptom assessment were performed after treatments with 150 or 300 mg itopride thrice a day （t.i.d.） for 30 d in random order, using an open label *** evaluating the safety of itopride, blood biochemical laboratory test was performed and the serum prolactin level was also examined before and after ***： Total symptom score was significantly decreased after treatment in 150- or 300-mg group. Itopride 300 mg was significantly effective than 150 mg on decreasing the total per cent time with pH〈4, total time with pH〈4 and DeMeester score. No serious adverse effects were observed with administration of itopride in both ***： Itopride 100 mg t.i.d, is effective on decreasing pathologic reflux in patient with GERD and therefore it has the potential to be effective in the treatment of this disease.

关键词： Gastro-esophageal reflux disease Itopride