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Does the advantage of transcutaneous oximetry measurements in diabetic foot ulcer apply equally to free flap reconstruction?

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World Journal of Clinical Cases 2023年第31期11卷 7570-7582页

作者： Da Woon Lee yong seon hwang Je Yeon Byeon Jun Hyuk Kim Hwan Jun Choi Department of Plastic and Reconstructive Surgery College of MedicineSoonchunhyang UniversityCheonan-si 31151South Korea

BACKGROUND Transcutaneous oxygen pressure(TcpO2)is a precise method for determining oxygen perfusion in wounded *** device uses either electrochemical or optical *** To evaluate the usefulness of TcpO2 measurements on free flaps(FFs)in diabetic foot ulcers(DFUs).METHODS TcpO2 was measured in 17 patients with DFUs who underwent anterolateral thigh(ALT)-FF surgery and compared with 30 patients with DFU without FF *** Significant differences were observed in the ankle-brachial index;duration of diabetes;and haemoglobin,creatinine,and C-reactive protein levels between the two ***2 values were similar between two groups except on postoperative days 30 and 60 when the values in the ALT-FF group remained50 *** Even if the flap is clinically stable,sympathectomy due to adventitia stripping during anastomosis and arteriovenous shunt progression due to diabetic polyneuropathy could lead to low TcpO2 values in the ALT-FF owing to its thick fat tissues,which is supported by the slow recovery of the sympathetic tone following ***,TcpO2 measurements in patients with DFU who underwent FF reconstruction may be less accurate than in those who did not.

关键词： Arteriovenous shunt Surgical Diabetic neuropathies Free tissue flaps Sympathectomy Blood gas monitoring Transcutaneous Diabetic angiopathies

Complicated calcified alloplastic implants in the nasal dorsum:A clinical analysis

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World Journal of Clinical Cases 2024年第18期12卷 3351-3359页

作者： yong-seon hwang Taek-Kyun Kim Dong-Jun Yang Si-Hyong Jang Da-Woon Lee Department of Plastic and Reconstructive Surgery College of MedicineSoonchunhyang UniversityCheonan-Si 31151South Korea Department of Plastic Surgery The PLUS Plastic Surgery ClinicSeoul 06035South Korea Department of Plastic Surgery CDU Plastic Surgery ClinicSeoul 06067South Korea Department of Pathology College of MedicineSoonchunhyang UniversityCheonan 31151Chungcheongnam-doSouth Korea

BACKGROUND In rhinoplasty,calcification around silicone implants is frequently observed in the tip dorsum(TD)***,based on a review of various literature,it is presumed that calcification in silicone implants occurs due to both inflammatory chemical reactions and physical friction against the *** calcification of nasal silicone implants not only results in the functional loss of the implants,but also leads to material ***,there is a lack of research on calcification of nasal silicone implants in the current *** To elucidate various clinical characteristics of calcification around nasal silicone implants,using histological and radiological *** This study analyzed data from 16 patients of calcified nasal implants,who underwent revision rhinoplasty for various reasons after undergoing augmentation rhinoplasty with silicone *** collected data included information on implant duration,implant types,location of calcification,presence of inflammatory reactions,and computed tomography(CT)*** The most common location of calcification,as visually analyzed,was in the TD area,accounting for 56%.Additionally,the analysis of CT scans revealed a trend of increasing Hounsfield Unit values for calcification with the duration of implantation,although this trend was not statistically significant(P=0.139).CONCLUSION Our study shows that reducing the frequency of calcification may be achievable by using softer silicone implants and by minimizing the damage to perioperative tissues.

关键词： Silicone implants Rhinoplasty Calcification Complication Hounsfield unit

A Lightweight Certificate-Based Aggregate Signature Scheme Providing Key Insulation

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Computers, Materials & Continua 2021年第11期69卷 1747-1764页

作者： yong-Woon hwang Im-Yeong Lee Department of Software Convergence in Soonchunhyang University Asan-si31538Korea

Recently,with the advancement of Information and Communications Technology(ICT),Internet of Things(IoT)has been connected to the cloud and used in industrial sectors,medical environments,and smart ***,if data is transmitted in plain text when collecting data in an IoTcloud environment,it can be exposed to various security threats such as replay attacks and data ***,digital signatures are *** integrity is ensured when a user(or a device)transmits data using a *** addition,the concept of data aggregation is important to efficiently collect data transmitted from multiple users(or a devices)in an industrial IoT ***,signatures based on pairing during aggregation compromise efficiency as the number of signatories *** signature methods(e.g.,identity-based and certificateless cryptography)have been *** methods pose key escrow and key distribution *** order to solve these problems,the use of aggregate signatures in certificate-based cryptography is being studied,and studies to satisfy the prevention of forgery of signatures and other security problems are being *** this paper,we propose a new lightweight signature scheme that uses a certificate-based aggregate signature and can generate and verify signed messages from IoT devices in an IoT-cloud *** this proposed method,by providing key insulation,security threats that occur when keys are exposed due to physical attacks such as side channels can be *** can be applied to create an environment in which data is collected safely and efficiently in IoT-cloud is environments.

关键词： Internet of things certificate-based aggregate signature key insulation cloud lightweight physical attack

Diagnostic accuracy of administrative database for bile duct cancer by ICD-10 code in a tertiary institute in Korea

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Hepatobiliary & Pancreatic Diseases International 2020年第6期19卷 575-580页

作者： Young-Jae hwang seon Mee Park Soomin Ahn Jongchan Lee Young Soo Park Nayoung Kim Department of Internal Medicine Seoul National University Bundang HospitalSeongnamKorea Department of Internal Medicine Chungbuk National University College of Medicine and Medical Research InstituteCheongjuKorea Department of Pathology Seoul National University Bundang HospitalSeoungnamKorea Department of Internal Medicine and Institute of Liver Research Seoul National University College of MedicineSeoulKorea Tumor Microenvironment Global Core Research Center Seoul National UniversitySeoulKorea

Background:Administrative database provides valuable information for large cohort studies,especially when tissue diagnosis is rather difficult such as the diagnosis for bile duct cancer(BDC).The aim of this study was to evaluate the diagnostic accuracy of administrative database for BDC by International Classification of Diseases(ICD)-10 codes in a tertiary ***:BDC and control groups were collected from 2003 to 2016 at Seoul National University Bundang *** of BDC were identified in the National Health Insurance Service(NHIS)database by ICD 10-code supported by V *** control group was selected from cases without ICD-10 codes for BDC.A definite or possible diagnosis was defined according to pathologic *** records,images,and pathology reports were analyzed to evaluate ICD-10 codes for ***,specificity,positive predictive value,and negative predictive value for BDC were analyzed according to diagnostic criteria and cancer ***:A total of 1707 patients with BDC and 1707 controls were *** those with BDC,1320(77.3%)were diagnosed by definite ***(99.4%)of them had *** of definite diagnosis was the highest for ampulla of Vater(88.9%),followed by that for extrahepatic(84.9%)and intrahepatic(68.3%)*** positive cases commonly had hepatocellular *** overall diagnosis of BDC,sensitivity,specificity,positive predictive value,and negative predictive value were 99.94%,98.33%,98.30%,and 99.94%,*** accuracies were similar regardless of diagnostic criteria or tumor ***:Administrative database for BDC collected according to ICD-10 code with V code shows good accuracy.

关键词： National Health Insurance Service Bile duct cancer ICD-10

A case of colohepatic penetration by a swallowed toothbrush

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World Journal of Gastroenterology 2006年第15期12卷 2464-2465页

作者： Min Ro Lee yong hwang Jong Hun Kim Department of Surgery Chonbuk National University Medical School San 2-20 Geumam-dongDeokjin-guJeonjuJeonbuk 561-180South Korea Research Institute of Clinical MedicineChonbuk National University Medical SchoolSan 2-20 Geumam-dongDeokjin-guJeonjuJeonbuk 561-180South Korea Department of Surgery Chonbuk National University Medical School San 2-20 Geumam-dongDeokjin-guJeonjuJeonbuk 561-180South Korea

Although foreign body ingestion is relatively common,toothbrush swallowing is rare. We report a case of a swallowed toothbrush which passed through the ileocecal valve and perforated the proximal transverse colon,then... 详细信息

关键词： Toothbrush Colohepatic penetration

Electrochemically metal-doped reduced graphene oxide films:Properties and applications

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Journal of Materials Science & Technology 2020年第5期40卷 72-80页

作者： Myung-Sic Chae Tae Ho Lee Kyung Rock Son Tae Hoon Park Kyo seon hwang Tae Geun Kim School of Electrical Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea Department of Clinical Pharmacology and Therapeutics College of MedicineKyung Hee UniversitySeoul 02447South Korea

The fine control of doping levels in graphene materials such as reduced graphene oxide(RGO)is important to properly manipulate their ambipolar transport characteristics for various device ***,conventional doping methods involve complex chemical reactions,large-scale doping processes,and poor ***,a simple and controllable electrochemical doping treatment(EDT),performed via the conductive channels created at the RGO surface by the application of an electric field,is introduced to tailor the electrical properties of RGO films.X-ray photoelectron spectroscopy and Raman spectroscopy measurements are performed to detect the presence of Ni atoms in RGO films after the EDT(EDT-RGO).Then,EDT-RGO field-effect transistors(FETs)are fabricated with different doping areas(0 to 100%fractional area)on the RGO active channel to investigate the effect and selective-area doping capability of the *** to p-type doping compensation by the intercalated Ni atoms,the electron mobility of the EDT-RGO FET decreases from 1.40 to 0.12 cm2 V-1s-1 compared with that of the undoped RGO-FET,leading to the conversion from ambipolar to unipolar p-type transfer characteristics.

关键词： Reduced graphene oxide Electrochemical doping treatment Electrical breakdown process Field-effect transistor

End-of-life batteries management and material flow analysis in South Korea

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Frontiers of Environmental Science & Engineering 2018年第3期12卷 55-67页

作者： Hyunhee Kim yong-Chul Jang Yeonjung hwang Youngjae Ko Hyunmyeong Yun Department of Environmental Engineering Chungnam National University Daejeon 34134 South Korea Waste to Energy Research Division Environmental Resources Research Department National Institute of Environmental Research Incheon 22689 South Korea Daejeon Green Environment Center Daejeon 34134 South Korea

Consumers increasingly have worn-out batteries as electrical and electronic equipment with new technical developments are introduced into the market and quickly replace older models. As a result, large amounts of end-of-life （EOL） or waste batteries are generated. Such batteries may contain a variety of materials that includes valuable resources as well as toxic elements. Thus, the proper recycling and management of batteries is very important from the perspective of resource conservation and environmental effect. The collection and recycling of EOL batteries is relatively low in South Korea compared to other countries, although an extended producer responsibility （EPR） policy was adopted for battery recycling in 2003. In this study, the management and material flow of EOL batteries is presented to determine potential problems and quantitative flow, based on literature review, site visits to battery recycling facilities, and interviews with experts in the Korea Battery Recycling Association （KBRA）, manufacturers, and regulators in government. The results show that approximately 558 tons of manganese-alkaline batteries, the largest fraction among recycling target items, was disposed in landfills or incinerators in 2015, while approximately 2,000 tons of batteries were recovered at a recycling facility by simple sorting and crushing processes. By raising environmental awareness, more diverse and effective collection systems could be established for consumers to easily dispose of EOL batteries in many places. Producers, retailers and distributors in South Korea should also play an important role in the collection of EOL batteries from consumers. Lithium-ion batteries from many electronic devices must be included in the EPR system for resource recovery.

关键词： End-of-life battery Recycling Material flow analysis (MFA)Extended producer responsibility (EPR)Resource recovery

Crushing behavior of lightmass structural member

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中国有色金属学会会刊：英文版 2009年第B9期19卷 276-279页

作者： Kil-Sung LEE yong-June YANG Woo-Chae hwang In-Young YANG Department of Mechatronics Chosun University of Science and Technology Department of Advanced Part and Materials Engineering Chosun University Department of Mechanical Design Engineering Chosun University

Carbon fiber reinforced plastic (CFRP) of the advanced composite materials is widely used in lightmass structural materials of air planes, ship and automobiles because of high strength and stiffness. In this study, experimental investigation was performed for each specimen. The square section members consist of aluminum, CFRP and hybrid (aluminum/CFRP) member, and hat-shaped section members consist of CFRP and hybrid (aluminum/CFRP) members specimen. Based on the collapse characteristics of aluminum square section member, the collapse characteristics and energy absorption capability of hat-shaped section members were analyzed. The axial static collapse tests were carried out for each section member. The collapse modes and the energy absorption capability of the members were analyzed. In the lightmass design aspect, the collapse characteristics and energy absorption capability of the members were compared.

关键词：碳纤维增强复合材料碳纤维复合材料能量吸收能力行为构件破碎航空飞机 CFRP

Gene expression profiling:Canonical molecular changes and clinicopathological features in sporadic colorectal cancers

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World Journal of Gastroenterology 2008年第43期14卷 6662-6672页

作者： Jin Cheon Kim seon Young Kim seon Ae Roh Dong-Hyung Cho Dae Dong Kim Jeong Hyun Kim yong Sung Kim Department of Surgery University of Ulsan College of Medicine and Asan Medical Centerand Laboratory of Cancer Biology & GeneticsAsan Institute for Life SciencesSeoul 138-736South Korea Medical Genomics Research Center Korea Research Institute of Bioscience & BiotechnologyDaejeon 305-806South Korea

AIM： To investigate alternative or subordinate pathways involved in colorectal tumorigenesis and tumor growth, possibly determining at-risk populations and predicting responses to treatment. METHODS： Using microarray gene-expression analysis, we analyzed patterns of gene expression relative to canonical molecular changes and clinicopathological features in 84 sporadic colorectal cancer patients, standardized by tumor location. Subsets of differentially expressed genes were confirmed by real-time reverse-transcript polymerase chain reaction （RT-PCR）. RESULTS： The largest number of genes identified as being differentially expressed was by tumor location, and the next largest number by lymphovascular or neural invasion of tumor cells and by mismatch repair （NMR） defects. Amongst biological processes, the immune response was significantly implicated in entire molecular changes observed during colorectal tumorigenesis （P 〈 0.001）. Amongst 47 differentially expressed genes, seven （PISD, NIBP, BAI2, STOML1, MRPL21, MRPL16, and MKKS） were newly found to correlate with tumorigenesis and tumor growth. Most location-associated molecular changes had distinct effects on gene expression, but the effects of the latter were sometimes contradictory. CONCLUSION： We show that several differentially expressed genes were associated with canonical molecular changes in sporadic colorectal cancers, possibly constituting alternative or subordinate pathways of tumorigenesis. As tumor location was the dominant factor influencing differential gene expression, location-specific analysis may identify location-associated pathways and enhance the accuracy of class prediction.

关键词： Colorectal adenocarcinomas Sporadic Gene expression Profiling Tumorigenesis