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80排螺旋CT多平面重建与DR平片对外伤性肋骨骨折的诊断价值研究

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中国CT和MRI杂志 2024年第2期22卷 160-161页

作者：李振李春晨朱永玲上海市嘉定区中心医院上海201899 上海市普陀区利群医院上海200333

目的探讨80排螺旋计算机断层扫描(CT)多平面重建与数字化X线摄影(DR)平片对外伤性肋骨骨折的诊断价值。方法回顾性选取2021年1月-2023年1月收治的68例外伤性肋骨骨折患者作为研究对象,所有患者均行80排螺旋CT检查和DR检查,比较两种检测... 详细信息

目的探讨80排螺旋计算机断层扫描(CT)多平面重建与数字化X线摄影(DR)平片对外伤性肋骨骨折的诊断价值。方法回顾性选取2021年1月-2023年1月收治的68例外伤性肋骨骨折患者作为研究对象,所有患者均行80排螺旋CT检查和DR检查,比较两种检测方法对外伤性肋骨骨折的诊断价值。结果68例外伤性肋骨骨折患者,最终临床诊断显示骨折位置104处,以最终临床检查为依据,螺旋CT多平面重建的确诊率高于DR检查,漏诊率和误诊率低于DR检查,差异具有统计学意义(χ^(2)=16.413;χ^(2)=9.789;χ^(2)=6.178,P<0.05);螺旋CT多平面重建的准确度和敏感度高于DR检查,差异具有统计学意义(准确率:89.71%vs 69.12%,χ^(2)=8.815,P<0.05;特异度:87.80%vs 65.85%,χ^(2)=5.549,P<0.05)。结论相较于DR平片,80排螺旋CT检查可提高对外伤性肋骨骨折诊断的准确度和敏感度。

关键词：外伤性肋骨骨折计算机断层扫描多平面重建

Signaling Role of Sucrose Metabolism in Development

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Molecular Plant 2012年第4期5卷 763-765页

作者： yong-ling Ruan Australia-China Research Centre for Crop Improvement University of Newcastle Callaghan NSW 2308 Australia School of Environmental and Life Sciences University of Newcastle Callaghan NSW 2308 Australia

In most higher plants, sucrose is the primary organic carbon that is translocated through phloem from photosynthetic leaves （source） into non-photosynthetic tissues （sink） such as seed, fruit, and root. After phloem unloading in sinks, sucrose needs to be degraded into hexoses for diverse use by either invertase （Inv） that hydrolyses sucrose into glucose and fructose or sucrose synthase （Sus） that degrades sucrose into UDPglucose and fructose. By generating hexoses and their derivates, Inv- or Sus-mediated sucrose metabolism and re- lated transport process provide （1） energy source to power cel- lular processes; （2） starting molecules convertible to numerous metabolites and building blocks for synthesizing essential pol- ymers including starch, cellulose, callose, and proteins; and （3） a mechanism to reduce sucrose concentration at the unloading sites to facilitate its source-to-sink translocation, thereby pre- venting feedback inhibition on photosynthesis and sustaining carbon flow at the whole-plant level.

关键词： COTTON FIBER CELL-WALL INVERTASE SYNTHASE SENESCENCE ABORTION GENES

Boosting Seed Development as a New Strategy to Increase Cotton Fiber Yield and Quality

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Journal of Integrative Plant Biology 2013年第7期55卷 572-575页

作者： yong-ling Ruan Department of Biology School of Environmental and Life SciencesThe University of Newcastle Australia Australia-China Research Centre for Crop ImprovementThe University of Newcastle

Cotton （Gossypium spp.） is the most important textile crop worldwide due to its cellulosic mature fibers, which are single-celled hairs initiated from the cotton ovule epidermis at anthesis. Research to improve cotton fiber yield and quality in recent years has been largely focused on identifying genes regulating fiber cell initiation, elonga- tion and cellulose synthesis. However, manipulating some of those candidate genes has yielded no effect or only a marginally positive effect on fiber yield or quality. On the other hand, evolutionary comparison and transgenic studies have clearly shown that cotton fiber growth is intimately controlled by seed development. Therefore,I propose that enhancing seed development could be a more effective and achievable strategy to increase fiber yield and quality.

关键词： Auxin cotton fiber seed development sugars seed maternal and filial tissues.

基于SpringBoot和Vue框架的高校统战工作服务信息管理系统的设计与实现

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广东轻工职业技术学院学报 2024年第2期23卷 16-23页

作者：凌勇李金忠黄启华王勤宇秦嘉超井冈山大学电子与信息工程学院江西吉安343009

针对高校统战工作较为传统化、宣传力度不够、工作成果展示不够全面等问题,采用当前主流框架技术,包括SpringBoot、Vue和Uni-App等前后端框架,MySQL、Redis和ElasticSearch等数据库技术以及Echarts开源可视化图表库、WebSocket全双工通... 详细信息

针对高校统战工作较为传统化、宣传力度不够、工作成果展示不够全面等问题,采用当前主流框架技术,包括SpringBoot、Vue和Uni-App等前后端框架,MySQL、Redis和ElasticSearch等数据库技术以及Echarts开源可视化图表库、WebSocket全双工通信协议和Nginx反向代理等前沿技术,设计与实现了一个高校统战工作服务信息管理系统。该系统分为PC端后台管理子系统、PC端可视化展示子系统和移动App端三大子系统,其中移动App端包括业绩管理、新闻管理、互动交流管理等功能模块。本系统具有较好的可扩展性和可维护性,可提高高校统战工作的管理效率和用户体验满意度,可为统战工作的信息化建设提供有力支持。

关键词：高校统战工作 Spring Boot框架 Uni-App框架 Vue框架 Echarts可视化图表库

精神分裂症患者基于移动医疗APP的认知矫正联合干预方案的构建

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护理学报 2024年第9期31卷 1-4页

作者：文敏陈兵周永玲刘娟朱晓丹宁夏医科大学护理学院宁夏银川750004 宁夏宁安医院宁夏银川750004 宁夏医科大学总医院宁夏银川750004

目的构建精神分裂症患者认知矫正联合干预方案,为开展基于移动端的精神分裂症患者认知干预提供参考依据。方法采用文献分析法,将认知矫正治疗与药物管理技能训练相结合,初步拟定基于移动医疗APP的认知矫正联合干预方案草案,选取14名专... 详细信息

目的构建精神分裂症患者认知矫正联合干预方案,为开展基于移动端的精神分裂症患者认知干预提供参考依据。方法采用文献分析法,将认知矫正治疗与药物管理技能训练相结合,初步拟定基于移动医疗APP的认知矫正联合干预方案草案,选取14名专家进行2轮德尔菲专家函询,进一步修订形成基于移动医疗APP的认知矫正联合干预方案终稿。结果2轮专家函询问卷有效回收率分别为93%、100%;专家权威系数为0.860;2轮咨询中重要性和可行性的变异系数均<0.25;第2轮专家咨询重要性和可行性的肯德尔协调系数为0.282、0.225(P均<0.05)。最终形成的干预方案包括4项主题、15项认知策略、16项认知练习。结论基于移动医疗APP的认知矫正联合干预方案经过专家函询,具备一定的严谨性、可行性和潜在价值,能够为精神分裂症患者开展基于移动端的认知干预提供参考依据。

关键词：精神分裂症移动医疗APP 认知矫正药物自我处置技能联合

一种基于贝叶斯的广义Pareto分布变点估计

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遵义师范学院学报 2024年第1期26卷 108-112页

作者：王国琴吴有富许婷欧永玲贵州民族大学数据科学与信息工程学院贵州贵阳550025 贵州交通职业技术学院贵州贵阳550025

文章研究广义Pareto分布单变点的估计问题,利用贝叶斯方法对广义Pareto分布变点进行估计,模拟结果表明,贝叶斯方法能获得更好的效果。同时将贝叶斯方法与基于KL散度似然比统计量的极大似然法比较,得出贝叶斯方法效果更好。

关键词：广义Pareto分布贝叶斯估计极大似然估计

采用STM32单片机的无线医务呼叫系统设计

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制造业自动化 2024年第6期46卷 209-214页

作者：申康何永玲余森基蒙宁佳王月武北部湾大学机械与船舶海洋工程学院广西钦州535011 广西大学电气工程学院广西南宁530004 广西海洋工程装备与技术重点实验室广西钦州535011 广西高校北部湾近海海洋工程装备与技术重点实验室广西钦州535011 广西科技大学自动化学院广西柳州545006

针对传统有线呼叫系统成本高,布线麻烦,建造周期长,线路易老化磨损等诸多缺点,设计了一套应用于医疗和卫生机构的无线呼叫系统,系统整体分为病房端、控制端和接收端三个模块。采用矩阵键盘来模拟病房号进行呼叫和清除呼叫,NRF24L01无线... 详细信息

针对传统有线呼叫系统成本高,布线麻烦,建造周期长,线路易老化磨损等诸多缺点,设计了一套应用于医疗和卫生机构的无线呼叫系统,系统整体分为病房端、控制端和接收端三个模块。采用矩阵键盘来模拟病房号进行呼叫和清除呼叫,NRF24L01无线模块进行传输,STM32单片机进行处理,控制端用OLED显示模块显示分配的病房号和等待分配的病房号,便携护士从机会显示呼叫的病房号且蜂鸣器响应。系统不用布线,操作便捷,安装方便。实验结果表明该各模块间通信良好,能准确显示病房呼叫信息,具有容错中断机制。系统成本低、配置灵活、医护人员路程上耗费时间比传统有线呼叫系统减少22%以上。

关键词：无线呼叫病房 STM32 NRF24L01模块

Cytochrome P45026A1 Contributes to the Maintenance of Neuropathic Pain

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Neuroscience Bulletin 2024年第3期40卷 293-309页

作者： De-Li Cao ling-Jie Ma Bao-Chun Jiang Qiang Gu yong-Jing Gao Institute of Pain Medicine and Special Environmental Medicine Co-innovation Center of NeuroregenerationNantong UniversityNantong226019China Nantong University Medical School Nantong226001China Department of Pain Management The Affiliated Hospital of Nantong UniversityNantong226001China

The cytochrome P450 proteins(CYP450s)have been implicated in catalyzing numerous important biological reactions and contribute to a variety of diseases.CYP26A1,a member of the CYP450 family,carries out the oxidative metabolism of retinoic acid(RA),the active metabolite of vitamin A.Here we report that CYP26A1 was dramatically upregulated in the spinal cord after spinal nerve ligation(SNL).CYP26A1 was mainly expressed in spinal neurons and astrocytes.HPLC analysis displayed that the content of all-trans-RA(at-RA),the substrate of CYP26A1,was reduced in the spinal cord on day 7 after SNL.Inhibition of CYP26A1 by siRNA or inhibition of CYP26A1-mediated at-RA catabolism by talarozole relieved the SNL-induced mechanical allodynia during the maintenance phase of neuropathic pain.Talarozole also reduced SNL-induced glial activation and proinflammatory cytokine production but increased anti-inflammatory cytokine(IL-10)production.The RA receptors RARα,RXRβ,and RXRγwere expressed in spinal neurons and glial cells.The promoter of Il-10 has several binding sites for RA receptors,and at-RA directly increased Il-10 mRNA expression in vitro.Finally,intrathecal IL-10 attenuated SNL-induced neuropathic pain and reduced the activation of astrocytes and microglia.Collectively,the inhibition of CYP26A1-mediated at-RA catabolism alleviates SNL-induced neuropathic pain by promoting the expression of IL-10 and suppressing glial activation.CYP26A1 may be a potential therapeutic target for the treatment of neuropathic pain.

关键词： CYP26A1 Microglia Astrocytes ERK P38 IL-10 Neuropathic pain

FPR1 Antagonist (BOC-MLF) Inhibits Amniotic Epithelial-mesenchymal Transition

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Current Medical Science 2024年第1期44卷 187-194页

作者： Xiao-mei HUANG E LIAO Jun-qun LIAO Ya-ling LIU yong SHAO Department of Obstetrics and Gynecology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China Department of Obstetrics Maternal and Child Health Hospital of Hubei ProvinceWuhan 430070China Medical Laboratory Science The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China Department of Obstetrics Yubei Maternity and Child Healthcare HospitalChongqing 400042China

Objective:Premature rupture of membranes(PROM)is a common pregnancy disorder that is closely associated with structural weakening of fetal membranes.Studies have found that formyl peptide receptor 1(FPR1)activates inflammatory pathways and amniotic epithelial-mesenchymal transition(EMT),stimulates collagen degradation,and leads to membrane weakening and membrane rupture.The purpose of this study was to investigate the anti-inflammatory and EMT inhibitory effects of FPR1 antagonist(BOC-MLF)to provide a basis for clinical prevention of PROM.Methods:The relationship between PROM,FPR1,and EMT was analyzed in human fetal membrane tissue and plasma samples using Western blotting,PCR,Masson staining,and ELISA assays.Lipopolysaccharide(LPS)was used to establish a fetal membrane inflammation model in pregnant rats,and BOC-MLF was used to treat the LPS rat model.We detected interleukin(IL)-6 in blood from the rat hearts to determine whether the inflammatory model was successful and whether the anti-inflammatory treatment was effective.We used electron microscopy to analyze the structure and collagen expression of rat fetal membrane.Results:Western blotting,PCR and Masson staining indicated that the expression of FPR1 was significantly increased,the expression of collagen was decreased,and EMT appeared in PROM.The rat model indicated that LPS caused the collapse of fetal membrane epithelial cells,increased intercellular gaps,and decreased collagen.BOC-MLF promoted an increase in fetal membrane collagen,inhibited EMT,and reduced the weakening of fetal membranes.Conclusion:The expression of FPR1 in the fetal membrane of PROM was significantly increased,and EMT of the amniotic membrane was obvious.BOC-MLF can treat inflammation and inhibit amniotic EMT.

关键词： formyl peptide receptor 1 BOC-MLF epithelial-mesenchymal transition premature rupture of membranes