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Distinctive clinical features of spontaneous pneumoperitoneum in neonates: A retrospective analysis

World Journal of Clinical Cases 2022年第23期10卷 8124-8132页

作者： Soo-Hong Kim yong-hoon cho Hae-Young Kim Department of Surgery Pusan National University Yangsan HospitalPusan National University School of MedicineYangsan 50612South Korea Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan HospitalYangsan 50612South Korea

BACKGROUND Spontaneous pneumoperitoneum(SP) without gastrointestinal perforation rarely occurs in neonates, with most SP cases being idiopathic. Although SP usually follows a benign clinical course with favorable prognosis, it can become lifethreatening in certain situations. In these cases, urgent surgical intervention may be required. Therefore, it may be difficult to decide when or how to perform prompt *** To demonstrate the distinct clinical features of SP to guide appropriate management by comparing characteristics between SP and typical pneumoperitoneum secondary to gastrointestinal *** We retrospectively reviewed electronic medical records and identified 37 neonates with radiological evidence of pneumoperitoneum who were treated at our institution. Clinical variables were compared between neonates with SP without gastrointestinal perforation(Group A) and those with pneumoperitoneum secondary to gastrointestinal perforation(Group B). Clinical variables between groups were compared using Student’s t-test and the chi-square test. The risk factors related to mortality were examined using multi-logistic regression *** Group A comprised 35.1%(13/37) of the patients. The frequency of persistent pulmonary hypertension(53.8%) and pneumothorax(46.2%) before the development of pneumoperitoneum was significantly higher in group A than in group B(P =0.004). Platelet count and partial pressure of arterial oxygen(PaO) were significantly lower in group A(P = 0.015 and 0.025, respectively). Overall mortality was significantly higher in group A than in group B(76.9% vs 16.7%, P = 0.001). Only preterm infants were significantly associated with high mortality(P = 0.041;odds ratio = 18.0). Accompaniment with persistent pulmonary hypertension and pneumothorax were also significantly high(P = 0.004) in group A, but these were not strongly associated with high *** This study identified a higher mortality rate in patients w

关键词： Spontaneous pneumoperitoneum Thrombocytopenia Persistent pulmonary hypertension Pneumothorax Preterm

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Thermodynamic model for deoxidation of liquid steel considering strong metal-oxygen interaction in the quasichemical model framework

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 988-1002页

作者： yong-Min cho Youn-Bae Kang Graduate Institute of Ferrous and Eco Materials Technology Pohang University of Science and TechnologyPohangKyungbuk37673Rep.of Korea N.EX.T Hub POSCO HoldingsPohangKyungbuk37673Rep.of Korea Department of Materials Science and Engineering Pohang University of Science and TechnologyPohangKyungbuk37673Rep.of Korea

Herein,a thermodynamic model aimed at describing deoxidation equilibria in liquid steel was *** model provides explicit forms of the activity coefficient of solutes in liquid steel,eliminating the need for the minimization of internal Gibbs energy preliminarily when solving deoxidation *** elimination of internal Gibbs energy minimization is particularly advantageous during the coupling of deoxidation equilibrium calculations with computationally intensive approaches,such as computational fluid *** model enables efficient calculations through direct embedment of the explicit forms of activity coefficient in the computing *** proposed thermodynamic model was developed using a quasichemical approach with two key approximations:random mixing of metallic elements(Fe and oxidizing metal) and strong nonrandom pairing of metal and oxygen as nearest *** these approximations,the quasichemical approach yielded the activity coefficients of solutes as explicit functions of composition and temperature without requiring the minimization of internal Gibbs energy or the coupling of separate *** model was successfully applied in the calculation of deoxidation equilibria of various elements(Al,B,C,Ca,Ce,Cr,La,Mg,Mn,Nb,Si,Ti,V,and Zr).The limitations of the model arising from these assumptions were also discussed.

关键词： deoxidation equilibria thermodynamics quasichemical approach computational fluid dynamics

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Surgical perspectives of symptomatic omphalomesenteric duct remnants: Differences between infancy and beyond

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World Journal of Clinical Cases 2021年第36期9卷 11228-11236页

作者： Ayoung Kang Soo-Hong Kim yong-hoon cho Hae-Young Kim Department of Surgery Pusan National University Yangsan HospitalYangsan 50612South Korea Department of Surgery Pusan National University School of MedicineYangsan 50612South Korea Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan HospitalYangsan 50612South Korea

BACKGROUND The clinical manifestations of omphalomesenteric duct remnant(OMDR)can vary with the age at diagnosis,from asymptomatic incidental findings to symptoms related to gastrointestinal *** lifelong complication rates are reported as 4%-34%,and complications are more common in patients younger than 2 years of *** authors attempted to identify different clinical features and management for the various pediatric age *** To find surgical perspectives for the pediatric age-related variants of OMDR and make recommendations for optimal *** The medical records of pediatric patients diagnosed with OMDR were reviewed *** patients diagnosed based on incidental findings during other surgeries were *** patients were divided into two groups based on age:12 mo(beyond infancy).We analyzed the demographic characteristics,clinical manifestations,diagnostic tools,surgical procedures,and clinical outcomes of the patients and compared them for the age ***-squared and Fisher's exact tests were used for nominal scales and a Mann-Whitney test was used for ratio *** A total of 35 patients(7 infants,28 children beyond infancy)were finally *** both groups,Meckel's diverticulum(MD)was the most common type of OMDR,while umbilical lesions were more common in the infant group(P=0.006).Hematochezia and abdominal pain were common in the beyond infancy group,while umbilical lesions were the most frequent symptoms in the infant *** diagnostic tools were used,but Meckel's scan was most useful in diagnosing OMDR in patients with painless rectal *** invasive surgery was more commonly performed for children than for infants(P=0.016).Single-incision laparoscopic surgery(SILS)was performed for fifteen patients who underwent laparoscopic *** were only three cases of postoperative complications,and all patients survived in good *** The cli

关键词： Omphalomesenteric duct remnant Age Surgical Meckel's diverticulum Single-incision laparoscopic surgery Children

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Deep-learning-based gas identification by timevariant illumination of a single micro-LEDembedded gas sensor

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Light(Science & Applications) 2023年第5期12卷 826-837页

作者： Incheol cho Kichul Lee Young Chul Sim Jae-Seok Jeong Minkyu cho Heechan Jung Mingu Kang yong-hoon cho Seung Chul Ha Kuk-Jin Yoon Inkyu Park Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Physics Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea SENKO Co. Ltd.485Oesammi-DongOsan-SiGyeonggil-Do 18111Republic of Korea

Electronic nose(e-nose)technology for selectively identifying a target gas through chemoresistive sensors has gained much attention for various applications,such as smart factory and personal health *** overcome the crossreactivity problem of chemoresistive sensors to various gas species,herein,we propose a novel sensing strategy based on a single micro-LED(μLED)-embedded photoactivated(μLP)gas sensor,utilizing the time-variant illumination for identifying the species and concentrations of various target gases.A fast-changing pseudorandom voltage input is applied to the μLED to generate forced transient sensor responses.A deep neural network is employed to analyze the obtained complex transient signals for gas detection and concentration *** proposed sensor system achieves high classification(~96.99%)and quantification(mean absolute percentage error~31.99%)accuracies for various toxic gases(methanol,ethanol,acetone,and nitrogen dioxide)with a single gas sensor consuming 0.53 *** proposed method may significantly improve the efficiency of e-nose technology in terms of cost,space,and power consumption.

关键词： Deep illumination transient

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Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells

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World Journal of Gastroenterology 2009年第3期15卷 310-320页

作者： Chan Woo Cheon Dae Hwan Kim Dong Heon Kim yong hoon cho Jae Hun Kim Department of Surgery School of MedicineMedical Research InstitutePusan National UniversityBusan 602-739South Korea

AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor(PPAR)-γ and PPAR-γ agonists on stomach cancer ***:To determine the proliferation-suppressive effects of troglitazone and ciglitazone,SNU-216 and SNU-668 stomach cancer cells were plated in media containing 40 μmol/L troglitazone and ciglitazone at a density of 1 × 104 cells/*** 3,5 and 7 d,the cells were counted with a *** assess the appearance of PPAR-γ,a reverse-transcription polymerase chain reaction analysis was *** day 7,Western blotting was used to determine the effects of troglitazone and ciglitazone on the expression of p21 and phosphorylated-ERK(pERK) *** cytometry analysis was used to determine which portion of the cell cycle was delayed when troglitazone was used to suppress cell *** order to clarify the mechanism underlying the activity of troglitazone,microarray analysis was ***:PPAR-γ was manifested in both SNU-216 and SNU-668 *** and troglitazone suppressed cell growth,and troglitazone was a stronger suppressor of stomach cancer cells than ciglitazone,an inducer of cell cycle arrest in the G1 ***-668 cells were also determined to be more sensitive to ciglitazone and troglitazone than SNU-216 *** troglitazone and ciglitazone were administered to stomach cancer cells,levels of p21 expression were increased,but ERK phosphorylation levels were *** GW9662,an antagonist of PPAR-γ,was applied in conjunction with ciglitazone and troglitazone,the cell growth suppression effect was *** gene transcription program revealed a variety of alterations as the consequence of troglitazone treatment,and multiple troglitazone-associated pathways were *** genes whose expression was increased by troglitazone treatment were associated with cell development,differentiation,signal transmission between cells,and cell adhesion,and were also associated

关键词：胃癌细胞增生活性分子效应

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Electrically driven, phosphor-free, white light-emitting diodes using gallium nitride-based double concentric truncated pyramid structures

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Light(Science & Applications) 2016年第1期5卷 665-670页

作者： Seung-Hyuk Lim Young-Ho Ko Christophe Rodriguez Su-Hyun Gong yong-hoon cho Department of Physics and KI for the NanoCentury Korea Advanced Institute of Science and Technology291 Daehak-roYuseong-guDaejeon 34141Korea Electronics and Telecommunications Research Institute(ETRI) 218 Gajeong-roYuseong-guDaejeon 34129Korea The Laboratoire Nanotechnologies Nanosystémes(LN2)-CNRS UMI-3463 Institut Interdisciplinaire d’Innovation Technologique(3IT)Universitéde Sherbrooke3000 boulevard UniversitéJ1K 0A5QCCanada

White light-emitting diodes(LEDs)are becoming an alternative general light source,with huge energy savings compared to conventional ***,white LEDs using phosphor(s)suffer from unavoidable Stokes energy converting losses,higher manufacturing cost,and reduced thermal ***,we demonstrate electrically driven,phosphor-free,white LEDs based on three-dimensional gallium nitride structures with double concentric truncated hexagonal *** electroluminescence spectra are stable with varying *** origin of the emission wavelength is studied by cathodoluminescence and high-angle annular dark field scanning transmission electron microscopy *** variation of the carrier injection efficiency is also investigated by a comparative analysis between spatially resolved photoluminescence and electroluminescence.

关键词： indium gallium nitride light-emitting diodes phosphor-free three-dimensional structures white color

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Enhanced light emission from AlGaN/GaN multiple quantum wells using the localized surface plasmon effect by aluminum nanoring patterns

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Photonics Research 2018年第1期9卷 30-36页

作者： KYUNG ROCK SON BYEONG Ryong LEE MIN HO JANG HYUN CHUL PARK yong hoon cho TAE GEUN KIM School of Electrical Engineering Korea University Anam-ro 145 Seongbuk-gu Seoul 02841 South Korea Department of Physics and KI for the NanoCentury Korea Advanced Institute of Science and Technology Daejeon 305-701 South Korea

We investigate the localized surface plasmon(LSP) effect by Al nanorings on the AlGaN/GaN multiple quantum well(MQW) structure emitting at 365 nm. For this experiment, first, the size of Al nanorings is optimized to maximize the energy transfer(or coupling) between the LSP and MQW using the silica nanospheres. Then, the Al nanorings with an outer diameter of 385 nm, which exhibit a strong absorption peak in the near-ultraviolet region, are applied to the top surface of the AlGaN/GaN MQW. The photoluminescence(PL) intensity of the MQW structure with Al nanorings increased by 227% at 365 nm compared to that without Al *** improvement is mainly attributed to an enhanced radiative recombination rate in the MQWs through the energy-matched LSPs by the temperature-dependent PL and time-resolved PL analyses. The radiative lifetime was about two times shorter than that of the structure without Al nanorings at room temperature. In addition, the measured PL efficiency at room temperature of the structure with Al nanorings was 33%, while that of the structure without Al nanorings was 19%, implying that LSP-QW coupling together with the nanoring array pattern itself played important roles in the enhancement.

关键词：等离子体通讯技术能量转移量子

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Depolarization mitigated in ferroelectric Hf_(0.5)Zr_(0.5)O_(2)ultrathin films(<5 nm)on Si substrate by interface engineering

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Journal of Advanced Ceramics 2024年第3期13卷 282-292页

作者： Se Hyun Kim Younghwan Lee Dong Hyun Lee Geun Hyeong Park Hyun Woo Jeong Kun Yang yong Hyeon cho Young yong Kim Min Hyuk Park Department of Materials Science and Engineering College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Research Institute of Advanced Materials College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Inter-university Semiconductor Research Center College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Pohang Accelerator Laboratory Pohang University of Science&TechnologyPohang 790784Republic of Korea

(Hf,Zr)O_(2)offers considerable potential for next-generation semiconductor devices owing to its nonvolatile spontaneous polarization at the ***,scaling this material to sub-5 nm thickness poses several challenges,including the formation of an interfacial layer and high trap *** particular,a low-k SiO_(2)interfacial layer is naturally formed when(Hf,Zr)O_(2)films are directly grown on a Si substrate,leading to high depolarization fields and rapid reduction of the remanent *** address these issues,we conducted a study to significantly improve ferroelectricity and switching endurance of(Hf,Zr)O_(2)films with sub-5 nm thicknesses by inserting a TiO_(2)interfacial *** deposition of a Ti film prior to Hf_(0.5)Zr_(0.5)O_(2)film deposition resulted in a high-k TiO_(2)interfacial layer and prevented the direct contact of Hf_(0.5)Zr_(0.5)O_(2)with *** findings show that the high-k TiO_(2)interfacial layer can reduce the SiO_(2)/Si interface trap density and the depolarization field,resulting in a switchable polarization of 60.2μC/cm^(2)for a 5 nm thick Hf_(0.5)Zr_(0.5)O_(2)***,we propose that inserting a high-k TiO_(2)interfacial layer between the Hf_(0.5)Zr_(0.5)O_(2)film and the Si substrate may offer a promising solution to enhancing the ferroelectricity and reliability of(Hf,Zr)O_(2)grown on the Si substrate and can pave the way for next-generation semiconductor devices with improved performance.

关键词： ferroelectric charge trapping hafnia depolarization

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Phase separations in graded-indium content InGaN/GaN multiple quantum wells and its function to high quantum efficiency

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Journal of Semiconductors 2012年第5期33卷 13-16页

作者：郭洪英孙元平 yong-hoon cho Eun-Kyung Suh Hai-Joon Lee Rak-Jun choi Yoon-Bong Hahn Institute of Science and Technology for Opto-Electronic Information Yantai University Department of Physics Korea Advanced Institute of Science and Technology School of Semiconductor and Chemical Engineering Semiconductor Physics Research CenterChonbuk National University School of Chemical Engineering Chonbuk National University

Phase separations have been studied for graded-indium content In_xGa_（1-x）N/GaN multiple quantum wells（MQWs） with different indium contents by means of photoluminescence（PL）,cathodeluminescence（CL） and time-resolved PL（TRPL） *** the main emission peaks,all samples show another 2 peaks at the high and low energy parts of the main peaks in PL when excited at 10 *** images show a clear contrast for 3 samples,which indicates an increasing phase separation with increasing indium *** spectra at 15 K of the main emissions show an increasing delay of rising time with indium content,which means a carrier transferring from low indium content structures to high indium content structures.

关键词： carrier transfer phase separation graded-indium content multiple quantum wells

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Artificial optoelectronic synapse based on spatiotemporal irradiation to source-sharing circuitry of synaptic phototransistors

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InfoMat 2024年第2期6卷 131-141页

作者： Seungho Song Changsoon choi Jongtae Ahn Je-Jun Lee Jisu Jang Byoung-Soo Yu Jung Pyo Hong yong-Sang Ryu yong-hoon Kim Do Kyung Hwang Center for Opto-Electronic Materials and Devices Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Center for Spintronics Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea Division of Nanoscience&Technology KIST SchoolUniversity of Science and Technology(UST)SeoulRepublic of Korea School of Biomedical Engineering Korea UniversitySeoulRepublic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoulRepublic of Korea

To overcome the intrinsic inefficiency of the von Neumann architecture,neuromorphic devices that perform analog vector–matrix multiplication have been highlighted for achieving power-and time-efficient data *** particular,artificial synapses,of which conductance should be programmed to represent the synaptic weights of the artificial neural network,have been intensively researched to realize neuromorphic ***,inspired by excitatory and inhibitory synapses,we develop an artificial optoelectronic synapse that shows both potentiation and depression characteristics triggered only by optical *** design of the artificial optoelectronic synapse,in which excitatory and inhibitory synaptic phototransistors are serially connected,enables these characteristics by spatiotemporally irradiating the phototransistor channels with optical ***,a negative synaptic weight can be realized without the need for electronic components such as *** such attributes,the artificial optoelectronic synapse is demonstrated to classify three digits with a high recognition rate(98.3%)and perform image preprocessing via analog vector-matrix multiplication.

关键词： amorphous oxide semiconductor analog processing artificial synapse neuromorphic optoelectronics

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