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International Journal of Ophthalmology(English edition) 2013年第2期6卷 136-140页

作者： Ebru Eren Akar Veysi ner Cem Küükerdnmez yonca aydin akova Department of Ophthalmology Artvin State Hospital Department of Ophthalmology Recep Tayyip Erdogan University Medical School Department of Ophthalmology Izmir University Medical School Kavaklidere Bayindir Hospital

AIM: To compare the efficacies of subconjunctival bevacizumab, ranibizumab, and pegaptanib sodium injections for the inhibition of corneal neovascularization in an experimental rat model. METHODS: Sixteen corneas of 16 rats were chemically cauterized and randomized into four groups: bevacizumab group that treated with 0.05mL/1.25mg bevacizumab, ranibizumab group that treated with 0.05mL/0.5mg ranibizumab, pegaptanib group that treated with 0.05mL/0.15mg pegaptanib sodium, and control group that treated with 0.05mL saline solution. Digital photographs of the corneas were taken and analyzed using an image analysis software program. All corneas were excised and examined histologically on the 15 th day. RESULTS: Each treatment group had significantly less neovascularized corneal areas and fewer blood vessels than the control group (all P 0.05). CONCLUSION: Subconjunctival bevacizumab, ranibiz-umab, and pegaptanib sodium were effective with no corneal epitheliopathy for inhibiting corneal neovascularization after corneal burn in rats .Bevacizumab was more effective than ranibizumab and pegaptanib sodium.

关键词： corneal neovascularization bevacizumab ranibizumab pegaptanib subconjunctival injection

Does topical bevacizumab prevent postoperative recurrence after pterygium surgery with conjunctival autografting?

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International Journal of Ophthalmology(English edition) 2014年第3期7卷 512-516页

作者： Aylin Karalezli Cem Kucukerdonmez yonca A. akova Bengu Ekinci Koktekir Department of Ophthalmology School of Medicine Baskent University Konya 42080 Turkey Department of Ophthalmology School of Medicine Izmir University Izmir 35530 Turkey Department of Ophthalmology Bay|nd|r Hospital Ankara 06520 Turkey Department of Ophthalmology Seluk University Faculty of Medicine Konya 42050 Turkey

AIM:To assess the effect of topical bevacizumab use on postoperative pterygium recurrence in eyes who underwent pterygium excision with limbal-conjunctival autograft transplantation(LCAT).METHODS:eighty-eight eyes of 88 patients with primary pterygium were included.Pterygia were graded preoperatively from type 1 to type 3(type 1 atrophic,type3 inflamed)according to the inflammatory status.The eyes were preoperatively randomized to receive topical steroid and antibiotic treatment(group 1,46 eyes)and additional topical bevacizumab(5 mg/mL;group 2,42eyes)in the postoperative period.All eyes underwent pterygium excision and LCAT.Medications were tapered and discontinued at one month.Postoperative complications and recurrence rates were recorded.RESULTS:The mean follow-up duration was 29.3±4.2mo(24-52mo)and 28.5±3.4(24-48mo)in group 1 and2,respectively(P>0.05).There were no statistically significant differences regarding the age or gender between groups(P>0.05).Also,the difference between groups with respect to pterygium type was not significant.During the follow-up period,recurrence developed in 2 eyes(4.3%)in group 1,whereas in one eye(2.4%)in group 2.No statistically significant difference between groups was found in recurrence rates(P>0.05).No re-operation for recurrence was necessary during the follow-up period in both groups.CONCLUSION:Topical bevacizumab seems to have no additonal effect on pterygium recurrence after LCAT.

关键词： limbal-conjuctival autograft topical bevacizumab pterygium recurrence topical bevacizumab

Effect of 0.05% topical cyclosporine for the treatment of symptomatic subepithelial infiltrates due to adenoviral keratoconjunctivitis

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International Journal of Ophthalmology(English edition) 2016年第4期9卷 634-635页

作者： Ilkay Kilic Muftuoglu yonca A.akova Sirel G.Gungor Department of Ophthalmology Istanbul Training and Research Hospital Department of Ophthalmology Bayindir Kavaklidere Hospital Department of Ophthalmology Baskent University

Dear Sir,Iam yonca A.akova,MD-from the Department of Ophthalmology,Bayindir Kavaklidere Hospital,Turkey.I wrote this letter to evaluate the efficacy of 0.05%topical cyclosporine A（CsA）eye drops（Restasis Allergan,Irvine,USA）in symptomatic patients with recurrent subepithelial infiltrates（SEIs）due to adenoviral keratoconjunctivitis following steroid eye drops tapering or discontinuation.

关键词： subepithelial Effect of 0.05 cyclosporine symptomatic steroid letter Irvine drops recurrence corneal

Lyme Borreliosis with Opthalmologic Presentation

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Open Journal of Rheumatology and Autoimmune Diseases 2012年第4期2卷 85-87页

作者： Ayse Gultekingil Keser Rezan Topaloglu Mehmet Orhan Yelda Bilginer Esra Baskin yonca akova Department of Opthalmology Baskent University Faculty of Medicine Ankara Turkey. Department of Opthalmology Hacettepe University Faculty of Medicine Ankara Turkey Department of Pediatric Nephrology and Rheumatology Baskent University Faculty of Medicine Ankara Turkey Department of Pediatric Nephrology and Rheumatology Hacettepe University Faculty of Medicine Ankara Turkey Department of Pediatrics Hacettepe University Faculty of Medicine Ankara Turkey

Lyme disease is a tick-borne multisystemic disease with multiple clinical presentations including rheumatological conditions. We present a 12 year old girl complaining of fever, arthralgia and redness in her eyes which was found to be the result of panuveitis. Borrelia antibodies were positive and she received 21-day treatment regimen with Ceftriaxon with resolution of all complaints at the end of treatment. Lyme disease classically occurs in three stages starting with erythema migrans, however atypical presentations skipping this stage and presenting with opthalmologic involvement in form of uveitis can be seen.

关键词： Lyme Borreliosis Uveitis

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同一家庭3个姐妹色觉障碍(英文)

国际眼科杂志 2007年第4期7卷 909-913页

作者： Nimet ünay Gündogan Feride Iffet ■ahin ■ansal Gedik zge Pekdogan yonca akova Ba■kent大学医学院生理科 Ba■kent大学医学院医学遗传学科 Ba■kent大学医学院眼科 Ba■kent大学医学院

目的:评价我校医学生和她的家庭成员先天色觉障碍的遗传特征,以建立其遗传模式。方法:运用Ishihara(石原)假同色图试验测定色觉障碍,用FW100色调试验评估其类型。并进行眼科检查和遗传学研究,建立色盲家谱,并对她的家庭给予遗传学咨询... 详细信息

目的:评价我校医学生和她的家庭成员先天色觉障碍的遗传特征,以建立其遗传模式。方法:运用Ishihara(石原)假同色图试验测定色觉障碍,用FW100色调试验评估其类型。并进行眼科检查和遗传学研究,建立色盲家谱,并对她的家庭给予遗传学咨询。结果:眼科检测结果显示双眼最佳矫正视力为20/20(1.0),近视矫正屈光度-2D,裂隙灯检测和眼压测量结果在正常范围,眼底镜检查视神经、黄斑和周边视网膜均正常,其它外眼评估和神经学检测正常,先证者的姐妹和她父母的眼科检测也正常,3姐妹和父亲的IPPT试验错误得分为19～20/25,结果和红绿色盲中绿色觉异常者一致。染色体分析和卵巢周期均正常。结论:根据她家谱,她的色盲是伴X染色体的隐性外显率模式的遗传特征。

关键词：女性色盲群体筛查试验假同色图色觉障碍

Empirical Study About the Application of Knowledge Management in Selected Sector of Industry in Slovakia

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Chinese Business Review 2012年第1期11卷 92-98页

作者： Dana Kisel＇akova University of Presov Presov Slovakia

Acute effects of static stretching on peak and end-range hamstring-to-quadriceps functional ratios

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World Journal of Orthopedics 2015年第9期6卷 719-726页

作者： Ufuk Sekir Ramiz Arabaci Bedrettin akova Department of Sports Medicine Medical Faculty of Uludag University Department of Physical Education and Sport Education Faculty of Sport SciencesUludag University

AIM: To evaluate if static stretching influences peak and end-range functional hamstring-to-quadriceps(H/Q) strength ratios in elite women athletes. METHODS: Eleven healthy female athletes in an elite competitive level participated to the study. All the participants fulfilled the static stretching or non-stretching(control) intervention protocol in a randomized design on different days. Two static unassisted stretching exercises, one in standing and one in sitting position, were used to stretch both the hamstring and quadriceps muscles during these protocols. The total time for the static stretching was 6 ± 1 min. The isokinetic peak torque measurements for the hamstring and quadriceps muscles in eccentric and concentric modes and the calculations for the functional H/Q strength ratios at angular velocities of 60°/s and 180°/s were made before(pre) and after(post) the control or stretching intervention. The strength measurements and functional strength ratio calculations were based during the entire- and end-range of knee extension.RESULTS: The pre-test scores for quadriceps and hamstring peak torque and end range values were not significantly different between the groups(P > 0.05). Subsequently, although the control group did notexhibit significant changes in quadriceps and hamstring muscle strength(P > 0.05), static stretching decreased eccentric and concentric quadriceps muscle strength at both the 60°/s and 180°/s test speeds(P 0.05). Furthermore, the functional H/Q strength ratios exhibited no significant alterations during the entire and end ranges of knee extension both in the static stretching or the control intervention(P > 0.05

关键词： Elite women athletes Eccentric Concentric Static stretching Functional hamstring-to-quadriceps ratio Muscle strength

比较聚甲基丙烯酸甲酯与疏水性丙烯酸酯人工晶状体在小儿白内障手术中的应用（英文）

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国际眼科杂志 2018年第12期18卷 2119-2124页

作者： Gamze Ucan Gündüz Ahmet Tuncer Ozmen Berna akova Budak Uludag大学医学院、眼科土耳其布尔萨16059

目的:比较聚甲基丙烯酸甲酯(PMMA)与疏水性丙烯酸酯人工晶状体(IOLs)用于小儿白内障摘除联合人工晶状体植入术术后视力效果及并发症。方法:回顾性研究。包括63例117眼接受双侧小儿白内障手术和原发性人工晶状体植入术患者。将所有患者... 详细信息

目的:比较聚甲基丙烯酸甲酯(PMMA)与疏水性丙烯酸酯人工晶状体(IOLs)用于小儿白内障摘除联合人工晶状体植入术术后视力效果及并发症。方法:回顾性研究。包括63例117眼接受双侧小儿白内障手术和原发性人工晶状体植入术患者。将所有患者分为两组,组I包括30例58眼植入聚甲基丙烯酸甲酯人工晶状体患者;组II包括33例59眼植入疏水性丙烯酸酯人工晶状体患者。比较两组间的临床特点、屈光不正、最佳矫正视力(BCVA)和手术并发症。结果:患者平均年龄为5. 8(2～12)岁,平均随访时间为40. 5(6～196) mo。术后,80眼(68. 4%)中最佳矫正视力≥0. 5,两组间存在可比性。两组间视觉轴混浊情况分别为组I 28眼(48. 3%),组II 16眼(27. 1%),两组间差异有统计学意义(P=0. 018)。术后形成眼内晶状体脱位和粘连。综上所述,疏水性丙烯酸酯人工晶状体组的并发症明显少于聚甲基丙烯酸甲酯人工晶状体组(P=0. 020)。结论:采用原发性人工晶状体植入术行小儿白内障手术是一种安全的方法。相较于聚甲基丙烯酸甲酯人工晶状体,疏水性丙烯酸人工晶状体术后并发症更少。

关键词：疏水性丙烯酸人工晶状体小儿白内障聚甲基丙烯酸甲酯人工晶状体原发性人工晶状体植入术

Composite Nanofibers： Polymer-Wood Dust （Green Composites）

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材料科学与工程（中英文A版） 2013年第10期3卷 659-666页

作者： Eva Zemanova Karel Klouda Hana Buricova Jiri Chvojka Eva Kost'akova Vera Mansfeldova PetrMikes Marketa Weisheitelova State Office for Nuclear Safety Senovazne Namgsti 9 Praha 1 Czech Republic VSB Technical University of Ostrava Faculty of Safety Engineering Lumirova 13/630 Ostrava 700 30 Czech Republic Fire Rescue Service of the Czech Republic Piskova 42 Praha 4 Czech Republic Technical University of Liberec Studentsk6 2 Liberec Czech Republic J. Heyrovsky Institute of Physical Chemistry Academy of Sciences of the Czech Republic Czech Republic

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β—内酰胺类抗生素耐药性的发生机制及对策

美国医学会杂志（中文版） 1999年第6期18卷 J002-J003页

作者： Akalin,E akova,M