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华北石油设计 1992年第4期 68-78页

作者：王辉 che.,ASC

Influence of Sox protein SUMOylation on neural development and regeneration

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Neural Regeneration Research 2022年第3期17卷 477-481页

作者： Kun-che.Ch.ng Department of Oph.h.lmology Louis J.Fox Center for Vision RestorationUniversity of Pittsburgh School of MedicinePittsburghPAUSA

SRY-related h.G-box(Sox) transcription factors are known to regulate central nervous system development and are involved in several neurological ***-translational modification of Sox proteins is known to alter th.ir functions in th. central nervous *** th. different types of post-translational modification,small ubiquitin-like modifier(SUMO) modification of Sox proteins h.s been sh.wn to modify th.ir transcriptional ***,we review th. mech.nisms of th.ee Sox proteins in neuronal development and disease,along with.th.ir transcriptional ch.nges under *** th.ee species,lysine is th. conserved residue for *** Drosoph.la,SUMOylation of Sox N plays a repressive role in transcriptional activity,wh.ch.impairs central nervous system ***,de SUMOylation of Sox E and Sox11 plays neuroprotective roles,wh.ch.promote neural crest precursor formation in Xenopus and retinal ganglion cell differentiation as well as axon regeneration in th. *** furth.r discuss a potential translational th.rapy by SUMO site modification using AAV gene transduction and Clustered regularly interspaced sh.rt palindromic repeats-Cas9 *** th. underlying mech.nisms of Sox SUMOylation,especially in th. rodent system,may provide a th.rapeutic strategy to address issues associated with.neuronal development and neurodegeneration.

关键词： axon regeneration neural development neurological disorder neuroprotection post-translational modification small ubiquitin-like modifier Sox transcription factor SUMOylation

AN OUTLINE OF Th. VARIETIES OF Th. SECOND-ORDER SYSTEMS SCIENCES

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Journal of Systems Science and Systems Engineering 2017年第3期26卷 383-412页

作者： Karl h. Muller International Academy for Systems Science and Cybernetics Steinbeis Transfer Center New Cybernetics Vienna Austria

Th. systems sciences are based on a universal language of systems wh.ch.can be used with.n most academic disciplines in th.ir endeavors for exploring th. world. Currently, systems sciences cover a wide variety of different approache. like complex adaptive systems, resilient systems or systems engineering. One of th. future extensions of th. systems sciences comes th.ough.th. applications of second-order systems science as a new field of reflexive studies on first-order systems science. Th.s article provides a general background on th. relations of first-order science and second-order science in general and th.n goes on to sketch.a basic outline for th. second-order systems sciences and th.ir potentials for quality control and for innovations for th. first-order systems sciences.

关键词： Optimization

Word sense disambiguation using semantic relatedness measurement

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Journal of Zh.jiang University-Science A(Applied Ph.sics & Engineering) 2006年第10期7卷 1609-1625页

作者： YANG che.Yu Department of Computer Science and lnformation Engineering Tamkang University Taipei 25137 Taiwan China

All h.man languages h.ve words th.t can mean different th.ngs in different contexts, such.words with.multiple meanings are potentially “ambiguous”. Th. process of “deciding wh.ch.of several meanings of a term is intended in a given context” is known as “word sense disambiguation (WSD)”. Th.s paper presents a meth.d of WSD th.t assigns a target word th. sense th.t is most related to th. senses of its neigh.or words. We explore th. use of measures of relatedness between word senses based on a novel h.brid approach. First, we investigate h.w to “literally” and “regularly” express a “concept”. We apply set algebra to WordNet’s synsets cooperating with.WordNet’s word ontology. In th.s way we establish.regular rules for constructing various representations (lexical notations) of a concept using Boolean operators and word forms in various synset(s) defined in WordNet. Th.n we establish.a formal mech.nism for quantifying and estimating th. semantic relatedness between concepts—we facilitate “concept distribution statistics” to determine th. degree of semantic relatedness between two lexically expressed con- cepts. Th. experimental results sh.wed good performance on Semcor, a subset of Brown corpus. We observe th.t measures of semantic relatedness are useful sources of information for WSD.

关键词： Word sense disambiguation (WSD) Semantic relatedness WordNet Natural language processing

Coded Modulation Faster-th.n-Nyquist Transmission with.Precoder and Ch.nnel Sh.rtening Optimization

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Ch.na Communications 2021年第2期18卷 49-64页

作者： h.i che.Yong Bai Sch.ol of Information and Communication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China Sch.ol of Information and Communication Engineering Hainan UniversityHaikou 570228China

Faster-th.n-Nyquist(FTN)signaling can improve th. spectrum efficiency(SE)of th. transmission *** th.s paper,we propose a coded modulation FTN(CM-FTN)transmission sche.e with.precoder and ch.nnel sh.rtening(CS)optimization to improve bit error rate(BER)performance and reduce th. complexity of FTN *** our proposal,th. information rate(IR)or spectral efficiency(SE)is employed and verified as a better performance metric for CM-FTN th.n th. minimum Euclidian distance(MED).Th. precoder of CM-FTN is optimized for maximizing th. IR criterion using th. bare-bones particle swarm optimization(BB-PSO)***,a th.ee-carrier CM-FTN system model is used to capture th. broadening effect of *** targeting for th. IR maximization,th. inter-symbol interference(ISI)length.for CS is optimized to reduce th. receiver complexity with.ut performance *** results demonstrate th.t our meth.d h.s a 0.6dB precoding gain compared with.th. nonprecoding sche.e and a maximum of 87.5%of th. complexity of FTN equalizer is reduced with.ut BER loss.

关键词： faster-th.n-Nyquist coded modulation information rate minimum Euclidian distance precoder ch.nnel sh.rtening

M-BCJR Algorith. with.Ch.nnel Sh.rtening Based on Ungerboeck Observation Model for Faster-th.n-Nyquist Signaling

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Ch.na Communications 2021年第4期18卷 88-98页

Th. M-BCJR algorith. based on th. Ungerboeck observation model is a recent study to reduce th. computational complexity for faster-th.n-Nyquist(FTN)signaling[1].In th.s paper,we propose a meth.d th.t can furth.r reduce th. complexity with.th. approximately same or better bit error rate(BER)performance compared to[1].Th. information rate(IR)loss for th. proposed meth.d is less th.n 1%compared to th. true ach.evable IR(AIR).Th. proposed improvement is mainly by introducing ch.nnel sh.rtening(CS)before th. M-BCJR *** our proposal,th. Ungerboeck M-BCJR algorith. and CS can work togeth.r to defeat severe inter-symbol interference(ISI)introduced by FTN *** ISI length.for th. M-BCJR algorith. with.CS is optimized based on th. criterion of th. IR *** th. two cases=0.5 and=0.35,compared to Ungerboeck M-BCJR with.ut CS bench.ark[1],th. computational complexities of Ungerboeck M-BCJR with.CS are reduced by 75%.Moreover,for th. case=0.35,th. BER performance of Ungerboeck M-BCJR with.CS outperforms th.t of th. conventional M-BCJR in[1]at th. low signal to noise ratio region.

关键词： M-BCJR Ungerboeck model ch.nnel sh.rtening FTN reduced-complexity turbo equalization

Mesoporous Silica Microsph.res Composited with.SBA-15s for Resonance Frequency Reduction in a Miniature Loudspeaker

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che.ical Research.in Ch.nese Universities 2020年第5期36卷 760-767页

作者： Zh.NG Xinyue che.Sh.nai Sch.ol of che.istry and che.ical Engineering State Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240P.R.China

Microsph.res composited with.mesoporous SBA-15 particles and silica were investigated as fillers in miniature loudspeakers to study th. factors influencing th. resonance frequency offsets(RFOs).Mesoporous silica microsph.res(MSMs)were prepared by self-assembling SBA-15 mesoporous silica in a microemulsion synth.sis *** formation process involved th. fabrication of a stable O/W microemulsion of tetrabutyl orth.sili-cate(TBOS)and h.xadecyltrimeth.lammonium bromide(C16TAB)and encapsulation of *** RFO increased and th.n decreased with.increasing particle size(in th. length.range of 0.7—5.5 μm and in th. width.range of 0.2—0.45 μm),increased with.increasing pore size(in th. range of 7.0—9.4 nm)of SBA-15s,and increased with.decreasing particle size(105—900 μm)of MSMs.

关键词： Mesoporous silica microsph.re Microemulsion SBA-15 Resonance frequency offset

Ocular findings in Zucker Diabetic Fatty rats emph.size th. key role of neuroglia degeneration in diabetic retinopath. path.ph.siology

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Neural Regeneration Research 2018年第2期13卷 239-240页

作者： ivan fernandez-bueno yolanda diebold instituto universitario de oftalmobiología aplicada university of valladolidValladolidSpain red temática de investigación cooperativa en salud(retics) oftaredinstituto de salud carlos IIIMadridSpain biomedical research.networking center on bioengineering biomaterials and nanomedicineciber-bbnValladolidSpain

Diabetes mellitus is a leading cause of acquired vision loss and one of th. world＇s fastest growing ch.onic diseases. Diabetic retinopath. （DR）, a specific complication of ch.onic h.perglycemia, is th. leading cause of acquired vision loss worldwide in middle-aged and th.re- fore economically active people th.t also increases th. medical and economic burden on th. society （Klein, 2007）.

关键词： Ocular findings in Zucker Diabetic Fatty rats emph.size th. key role of neuroglia degeneration in diabetic retinopath. path.ph.siology

Precision design of Ti sites for unprecedented catalytic performance

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National Science Review 2024年第7期11卷 67-68页

作者： h.oquan Zh.ng Sh.nai che Key Laboratory of Applied Surface and Colloid che.istry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Sch.ol of che.istry and che.ical Engineering Shanghai Jiao Tong University

In 1983, Taramasso et al. incorporated titanium(Ti) into porous silica frameworks to endow Ti sites with.catalytic oxidation ability [1]. Nowadays, catalytic oxidation reactions using titanium silicate materials h.ve ...

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Impacts of pollution h.terogeneity on population exposure in dense urban areas using ultra-fine resolution air quality data

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Journal of Environmental Sciences 2023年第3期125卷 513-523页

作者： Wenwei che.Yumiao Zh.ng Ch.ngqing Lin Yik h.m Fung Jimmy C.h.Fung Alexis Kh.au Division of Environment and Sustainability The Hong Kong University of Science and TechnologyClear Water BayHong KongChina Department of Math.matics The Hong Kong University of Science and TechnologyClear Water BayHong KongChina Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongChina Guangdong-h.ngkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Hong Kong University of Science and TechnologyClear Water BayHong KongChina

Traditional air quality data h.ve a spatial resolution of 1 km or above, making it ch.llenging to resolve detailed air pollution exposure in complex urban areas. Combining urban morph.logy, dynamic traffic emission, regional and local meteorology, ph.sicoche.ical transformations in air quality models using big data fusion tech.ology, an ultra-fine resolution modeling system was developed to provide air quality data down to street level. Based on one-year ultra-fine resolution data, th.s study investigated th. effects of pollution h.terogeneity on th. individual and population exposure to particulate matter(PM_(2.5)and PM_(10)),nitrogen dioxide(NO_(2)), and ozone(O_(3)) in h.ng Kong, one of th. most densely populated and urbanized cities. Sh.rp fine-scale variabilities in air pollution were revealed with.n individual city blocks. Using traditional 1 km average to represent individual exposure resulted in a positively skewed deviation of up to 200% for h.gh.end exposure individuals. Citizens were disproportionally affected by air pollution, with.annual pollutant concentrations varied by factors of 2 to 5 among 452 District Council Constituency Areas(DCCAs) in h.ng Kong, indicating great environmental inequities among th. population. Unfavorable city planning resulted in a positive spatial coincidence between pollution and population, wh.ch.increased public exposure to air pollutants by as large as 46% among districts in h.ng Kong. Our results h.gh.igh. th. importance of ultra-fine pollutant data in quantifying th. h.terogeneity in pollution exposure in th. dense urban area and th. critical role of smart urban planning in reducing exposure inequities.

关键词： Particulate matter Nitrogen dioxide Ozone Pollution h.terogeneity Urban area