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Saturated hydraulic conductivity of compacted bentonite-sand mixtures before and after gas migration in artificial seawater

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第1期15卷 216-226页

作者： Yasutaka Watanabe Shingo Yokoyama Misato Shimbashi yoichi Yamamoto Takahiro Goto Sustainable System Research Laboratory Central Research Institute of Electric Power IndustryChibaJapan Science and Technology Department Nuclear Waste Management Organization of JapanTokyoJapan

To understand the self-healing property of an engineered barrier for radioactive waste disposal,the hydraulic conductivity of compacted bentoniteesand mixtures saturated with artificial seawater(SW)before and after gas migration was ***-and Ca-bentonites were mixed with fine sand at a ratio of 70%bentonite in dry *** aspects were considered during the experiment:the hydraulic conductivity of the specimen that was resaturated after gas migration and the distribution of water content immediately after gas migration to study gas migration *** gas migrated through the entire cross-section of the specimen,and gas breakthrough occurred in the equilibrium swelling pressure range ***,the gas flow rate reached a sufficient large value when the gas pressure was approximately twice the equilibrium axial pressure(the sum of swelling and confining pressures),which excluded the back *** the gas migration pathway was not visible when the specimen was observed immediately after gas migration,the water content distribution showed that several parts of the specimen with lower water content were connected in the direction of gas *** resaturation,the change in permeability was within a limited rangedtwo to three times larger than that before gas migration for each type of bentonite in *** slight change suggests that gas migration creates a pore structure that cannot be sealed via crystalline swelling of montmorillonite in SW,even if highly compacted bentonite is used under a constant-volume condition.

关键词： Bentonite Gas migration Hydraulic conductivity Seawater(SW) Self-healing

Vortices within the Separation Region in a Decelerating Channel Flow (Effect of Inlet Velocity Gradient)

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Journal of Thermal Science 2005年第4期14卷 341-345页

作者： yoichi KINOUE Toshiaki SETOGUCHI Mohammad MAMUN Norimasa SHIOMI Kenji KANEKO Department of Mechanical Engineering Saga University1HonjoSaga840-8502Japan

An experimental investigation was made into three-dimensional separated flow and the vortices within the flow separation in a decelerating channel flow generated by the suction from a porous side wall. The flows along the side and bottom walls were visualized by the surface tuft method. The turbulent internal flow was measured by the split-film probe to investigate the turbulent flow including the reverse flow. In the flow visualization for the strong decelerating flow （the suction flow ratio：0.8）, two typical flow patterns appear alternatively. One is that the flow near the bottom wall separates more upstream than the flow near the top wall and a clockwise vortex can be seen in the separation region. Another is the reversal flow pattern with a counterclockwise vortex. By the turbulent flow measurement using the split-film probe, two peaks of turbulence level are observed for the strong decelerating flow case. These peaks can be related with two flow patterns mentioned above.

关键词： vortices within the separation decelerating channel flow turbulent flow split-film probe

Does Property Right Transformation Improve Township and Village Enterprises Performance?

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China & World Economy 2006年第1期14卷 85-101页

作者： Zhixiong Du yoichi Izumida Professor Rural Development Institute Chinese Academy of Social Sciences Beijing China Professor Lab of Rural Finance Department of Agricultural and Resource Economics the University of Tokyo Tokyo Japan.

To date, few observations have been made about the performance improvement that resulted from the property right transformation of the collective-owned township and village enterprises （TVE） in the middle of 1990s. Using data collected from a questionnaire survey on the privatized TVE and their employees, the present paper provides some empirical evidence about this topic, and the analysis＇ suggests that property right transformation has had a positive impact on sample enterprises ＇performance, including business improvement, employment expansion, incremental investment and contributions to government revenues＇. The present study concludes that, from a transient viewpoint, the property right transformation has not distorted local governments＇ intentions to establish TVE in earlier years.

关键词： property right transformation township and village enterprises performance improvement

New approaches for archaeal genome-guided cultivation

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Science China Earth Sciences 2021年第10期64卷 1658-1673页

作者： Yinzhao WANG yoichi KAMAGATA Meng LI Feifei HAN Fengping WANG Xiang XIAO State Key Laboratory of Microbial Metabolism School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China Bioproduction Research Institute National Institute of Advanced Industrial Science and Technology(AIST)Tsukuba 310-8555Japan Shenzhen Key Laboratory of Marine Microbiome Engineering Institute for Advanced StudyShenzhen 518052China Department of Surgery Massachusetts General Hospital and Harvard Medical SchoolBoston MA 02114USA School of Oceanography Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Ocean Engineering Ocean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China

Archaea,one of the three domains of life along with Bacteria and Eukarya,contains ancient life forms such as methanogen that are observed today on Earth,and one lineage Asgard archaea is also considered the closest ancestor of ***,with the development of interdisciplinary studies from Earth and Life sciences,archaeal organisms are considered to play pivotal roles in geochemical cycling in ***,our understanding of the attributes,origin and evolution,geochemical and ecological functions of Archaea is hampered by the scarcity of archaeal isolates,which has represented a challenge to researchers for the last 40 ***-independent sequencing and phylogenomic analyses have demonstrated a considerable diversity of Archaea with more than 20 novel ***,only four archaeal phyla have cultured representatives,leaving large gaps in our knowledge of the metabolic capabilities and ecological functions of the majority of archaeal strains identified exclusively by DNA *** this review,we summarize the discovery and development of archaeal research,highlight the knowledge gap between uncultured and cultured archaeal microbes,and call on the importance of devoting greater research efforts to archaeal ***,we outlined new ideas and strategic approaches,namely,(1)genome-based methods,(2)microbial network information-based methods,(3)genome-scale model-guided methods,and(4)machine learning methods,to enable the cultivation of uncultivated archaeal microbes using accumulated high-throughput sequencing data.

关键词： Archaea Cultivation Next-generation sequencing Uncultured archaea Genome Metabolic network

Reprogramming of germ cells into pluripotency

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World Journal of Stem Cells 2016年第8期8卷 251-259页

作者： yoichi Sekita Toshinobu Nakamura Tohru Kimura Laboratory of Stem Cell Biology Department of Biosciences Kitasato University School of Science Laboratory of Epigenetic Regulation Department of Animal Bioscience Nagahama Institute of Bio-Science and Technology

Primordial germ cells(PGCs) are precursors of all gametes, and represent the founder cells of the germline. Although developmental potency is restricted to germ-lineage cells, PGCs can be reprogrammed into a pluripotent state. Specifically, PGCs give rise to germ cell tumors, such as testicular teratomas, in vivo, and to pluripotent stem cells known as embryonic germ cells in vitro. In this review, we highlight the current knowledge on signaling pathways, transcriptional controls, and post-transcriptional controls that govern germ cell differentiation and de-differentiation. These regulatory processes are common in the reprogramming of germ cells and somatic cells, and play a role in the pathogenesis of human germ cell tumors.

关键词： Primordial germ cell Embryonic germ cell Germ cell tumor Reprogramming Induced pluripotent stem cell Small molecule compound Gene Signal Transcription factor

Three Dimensional Separation with Spiral-Focus in a Decelerating Duct Flow (Effect of Asymmetric Inlet Boundary Layer Thickness)

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Journal of Thermal Science 2003年第1期12卷 27-32页

作者： yoichi Kinoue Toshiaki Setoguchi Kenji Kaneko Mamun Mohammad Masahiro Inoue Department of Mechanical Engineering Saga University 1Department of Mechanical Engineering Saga University 1Department of Mechanical Engineering Saga University 1Department of Mechanical Engineering Saga University 1Department Honjo Saga 840-8502 Japan Honjo Saga 840-8502 Japan Honjo Saga 840-8502 Japan Honjo Saga 840-8502 Japanof Mechanical Engineering Science Kyushu University 6-10-1Hakozaki Higashi-ku Fukuoka 812-8581Japan

An experimental apparatus was developed to study the three dimensional separated flow with spiral-foci. The internal decelerating flow was generated by the air suction from a side wall to produce the separation on an opposite-side wall. The relation between the upstream boundary layer and the generation of spiral-foci in the separation region was observed by a tuft method. As a result, it was clarified that the spiral-focus type separation could be produced on the side wall and its behavior was closely related to the vortices supplied into the separation region from the boundary layer developing along top wall or bottom one.

关键词： three dimensional separation spiral-focus decelerating duct flow.

Flow Fields with Vortex in a Small Semi-open Axial Fan

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Journal of Thermal Science 2009年第4期18卷 294-300页

作者： Norimasa. Shiomi yoichi Kinoue Ying zi Jin Toshiaki Setoguchi Kenji Kaneko Department of Mechanical Engineering Saga University 1 Honjo-machi Saga 840-8502 Japan Institute of Mechatronics Zhejiang Sci-Tech University Xiasha Higher Educational Zone Hangzhou 310018 China

In order to clarify the effect of tip clearance （TC） size on fan performance and the flow field at rotor outlet in a small semi-open axial fan, the experimental investigation was carried out. The tip diameter of test fan rotor was 180mm and test TC sizes were lmm （TC=1mm） and 4mm （TC=4mm）. Fan characteristics tests were carried out for two cases of TC size and three-dimensional velocity fields at rotor outlet were measured using a single slant hot-wire probe at four flow-rate conditions. As a result, it was found that the pressure - flow-rate characteristics curves for two cases showed almost the same tendency. However, the ensemble averaged velocity profiles along radial measurement stations of TC-4mm largely changed compared with that of TC=1mm in cases of small flow-rate condition. From the phase-locked averaging results, it was also found that the vortex existed in the rotor outlet flow field of high flow-rate condition for each TC case. Compared with the vortices for TC=1mm and TC=4mm, the vortex for TC=4mm was stronger than that for TC=1mm.

关键词： fan semi-open type vortex tip clearance

Enhancing mechanism of intestinal absorption of highly lipophilic compounds using microemulsion e Quantitative analysis of the partitioning to the mesenteric lymph in intestinal cells

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Asian Journal of Pharmaceutical Sciences 2015年第3期10卷 186-193页

作者： Kazunori Iwanaga yoichi Higashiyama Makoto Miyazaki Masawo Kakemi Division of Pharmaceutics Osaka University of Pharmaceutical Sciences4-20-1 NasaharaTakatsukiOsaka 569-1094Japan

The purpose of this study was to quantify the effect of the fatty acid alkyl-chain length of a polyethylene glycol(PEG)glyceryl ester,which was used as a microemulsion oil component,on the partitioning of highly lipophilic compounds to the mesenteric lymph after oral *** blue N,a highly lipophilic anthraquinone derivative,was orally administered to lymph duct-cannulated and untreated rats in two kinds of different ***®50/13 and Gelucire®44/14 were used as the oil component with long chain and medium chain fatty acid portions,respectively,of PEG glyceryl esters in *** cumulative amount of oil blue N in lymph fluid was almost the same between the two microemulsions,although the transferred amount of oil component(triglyceride)in the lymph after administration of the Gelucire®50/13 microemulsion was significantly higher than that of the Gelucire®44/14 *** the other hand,the solubility of oil blue N in Gelucire®44/14 was much higher than that in Gelucire®50/*** significant differences were observed between microemulsions in the bioavailability of oil blue *** these data,the partitioning of oil blue N to the lymph was calculated using a mathematical model,showing that the partitioning ratios of oil blue N to the lymph fluid were almost the same for both *** solubility of oil blue N to the oil component of the microemulsions and the transfer of triglycerides to the lymph after administration of the microemulsions counteract each other,leading to similar partitioning ratios of oil blue N to the lymph.

关键词： Microemulsion Intestinal absorption Mesenteric lymph Partition Quantitative analysis

Measurement of Supersonic Jet Noise with Optical Wave Microphone System

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Journal of Thermal Science 2005年第4期14卷 352-356页

作者： Masataka KOSAKA Kunisato SETO MD.Tawhidul Islam KHAN yoichi NAKAZONO Department of Mechanical Engineering SAGA University1 Honjo-machiSaga-shiSaga 840-8502Japan Department of Mechanical Systems Engineering School of EngineeringKyushu Tokai University9-1-1 TorokuKumamoto 862-8652Japan

An optical wave microphone system is a new technique of sound measurement. This technique has been developed as a new plasma diagnostic technique to measure electron density fluctuations in the nuclear fusion research. Because the sound wave is a pressure or a density fluctuation, it is possible for this technique to measure the sound wave, too. The acoustical characteristics of the optical wave microphone system were examined by using a speaker as a first step. Next, feasibility of this device to measure jet noise was examined. It was found that the optical wave microphone system could measure the jet noise as well as a sound from speaker. Hence the optical wave microphone system can be considered one of the devices equivalent to condenser microphone. Because of these reason, this device is very convenient to scan the acoustic filed through jet flow from the inside to the out side and more preferable for not disturbing the observation field.

关键词： supersonic jet laser sound measurement optical wave microphone system.