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Abundances of 23 field RR Lyrae stars

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Research in Astronomy and Astrophysics 2013年第11期13卷 1307-1329页

作者： Shu Liu Gang Zhao Yu-Qin Chen yoichi takeda Satoshi Honda Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Graduate University of Chinese Academy of Sciences National Astronomical Observatory of Japan 2-21-1 Osawa Nishi-Harima Astronomical Observatory Center for Astronomy University of Hyogo

We present stellar parameters and abundances of 15 elements （Na, Mg, A1, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Ni, Cu, Y and Ba） for 23 field RR Lyrae variables based on high-resolution （R ~ 60 000） and high signal-to-noise （S/N~ 200） spectra obtained using the High Dispersion Spectrograph on the Subaru Telescope. Six stars in the sample have more than one spectrum observed at different pulsation phases. The derived abundance ratios of [X/Fe] for 14 elements （except for Ba） do not vary during the pulsation cycle. An interesting curve of [Ba/Fe] versus phase is detected for the first time and it shows decreasing [Ba/Fe] with increasing temperature at a given metallicity. Combining with data in the literature, abundances of most RR Lyrae stars as a function of [Fe/H] follow the same trends as those of dwarf stars, but [Sc/Fe] and [Y/Fe] ratios of RR Lyrae stars at solar metallicity are lower than those of dwarf stars. The kinematics of RR Lyrae stars indicate that three comparatively metal-rich RR Lyrae stars might originate from the thick disk and they show higher [a/Fe] ratios than RR Lyrae stars with thin disk kinematics. Among 23 RR Lyrae stars, two special objects are found with abnormal abundances; TV Lib has high [a/Fe], [Sc/Fe], [Y/Fe] and [Ba/Fe] ratios while TW Her has solar [a/Fe] but significantly lower [Sc/Fe], [Y/Fe] and [Ba/Fe] ratios as compared with other RR Lyrae stars.

关键词： techniques: spectroscopic -- stars: abundances -- stars: variables: RRLyrae

Amidine-bearing lipoplex targeting to hepatocyte cells

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Chinese Chemical Letters 2008年第9期19卷 1115-1118页

作者： Yasuya Kudo Kazunori Koiwai Kazuhiro Shimizu Shota Kusuki Mina Sakuragi Naohiko Shimada yoichi takeda Kazuo Sakurai Department of Chemical Process & Environments Faculty of Environmental EngineeringThe University of Kitakyushu1-1HibikinoWakamatsu-kuKitakyushuFukuoka 808-0135Japan TERUMO Corporation R & D Center 1500 InokuchiNakai-machiAshigarakami-gun Kanagawa 259-0151Japan

A lipoplex （i.e., pDNA#1/lipid complex and transfection reagent for pDNA delivery） containing galactosylceramide （GalCer） and an amidine-bearing lipid （TRX） was examined whether the bound pDNA was specifically ingested by hepatocyte via asialoglycoprotein receptor （ASGPR） and then expressed protein. Gel electrophoresis and small-angle X-ray scattering （SAXS） confirmed that the TRX-GalCer liposome#2 complexed with pDNA and the resultant lipoplex took a hexagonally packed inverted cylinder structure when the GalCer composition was less than 20 wt.% of the total lipid. When the lipoplex carrying pGL3 （luciferase-cording pDNA） was administrated to HepG2, the luciferase activity was increased with increasing the GalCer composition until it reached 3 wt.% and then decreased upon further addition of GalCer. When we added galactose itself as a competitor, the luciferase activity was decreased, while glucose did not show such decrease, suggesting that HepG2 ingested the lipoplex via ASGPR-mediated endocytosis. This paper indicated that the hexagonally packed inverted cylinder structures of lipoplex may not always provide excellent transfection and presented a possibility that the TRX lipoplex#3 can obtain a cellulartargeting ability through the receptors for oligosaccharide.

关键词： Gene theraphy Amidine Galactosylceramide Targeting

A possible substellar companion to the intermediate-mass giant HD 175679

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Research in Astronomy and Astrophysics 2012年第1期12卷 84-92页

作者： Liang Wang Bun＇ei Sato Gang Zhao Yu-Juan Liu Kunio Noguchi Hirovasu Ando Hideyuki Izumiura Eiji Kambe Masashi Omiya Hiroki Harakawa Fan Liu Xiao-Shu Wu yoichi takeda Michitoshi Yoshida Eiichiro Kokubo Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Department of Earth and Planetary Sciences Graduate Sclaooi of Science and EngineeringTokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo 152-8551 Japan National Astronomical Observatory of Japan National Institutes of Natural Sciences. MitakaTokyo 181-8588 Japan Okayama Astrophysical Observatory National Astronomical Observatory of Japan NationalInstitutes of Natural Sciences Asakuchi Okayama 719-0232 Japan Hiroshima Astrophysical Science Center Hiroshima University -1-3-1 KagamiyamaHigashi-Hiroshima 739-8526 Japan

We report the discovery of a substellar companion around the intermediate- mass giant HD 175679. Precise radial velocity data of the star from the Xinglong Station and the Okayama Astrophysical Observatory revealed a Keplerian velocity variation with an orbital period of 1366.8±5.7 d, a semiamplitude of 380.2±3.2 m s-1 and an eccentricity of 0.378± 0.008. Adopting a stellar mass of 2.7± 0.3 M, we obtain that the minimum mass of the HD 175679 b is 37.3± 2.8 M and the semimajor axis is 3.36±0.12 AU. This discovery is the second brown dwarf companion candidate from a joint planet-search program between China and Japan.

关键词： stars: individual (HD 175679) -- stars: brown dwarfs -- techniques:radial velocities

Symptomatic COVID-19 in University Students: A School-Wide Web-Based Questionnaire Survey during the Omicron Variant Outbreak

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Advances in Infectious Diseases 2024年第1期14卷 133-146页

作者： Mai Kitahara Hisami Sameshima Rie Tanuma Kumi Setoyama Yuka Yamaguchi Akiyo Kamachi Satoko Nakamura Mayuko Sakuma yoichi Kawaike Tamotsu Furuya Shinji Ijichi Health Service Center Kagoshima University Kagoshima Japan Center for Management of Information Technologies Kagoshima University Kagoshima Japan

Aim: To detect risk and preventive factors associated with the Omicron variant infection in university students, a combination of a web-based survey and multivariate logistic regression analysis was introduced as the front-line initiatives by the school health practitioners. Design: Questionnaire survey. Methods: The school-wide web-based questionnaire survey was conducted among our university students as a part of the annual health check-up in April, 2023. The positive outcome was confined to the first symptomatic COVID-19 onset during the Omicron variant outbreak. Results: In this self-administered survey, risk or protective associations were merely estimated statistically in university students (n = 5406). In measured factors, karaoke and club/group activities could maintain the statistical significance in adjusted odds ratios (ORs) as relative risk factors, and science course, measles/ rubella (MR) vaccination, and COVID-19 vaccination remained as relative protective factors in adjusted OR analyses. Club/group activities with member gathering and karaoke sing-along sessions in university students may frequently have WHO’s three Cs. These risk factors are still important topics for the infection control of COVID-19 in university students. Together with some recent reports from other researchers, the significant protective role of MR vaccine in our survey warrants further clinical investigation. If the breakthrough infection continuously constitutes the majority of infection, real data in test-negative case-control or web-based questionnaire design continue to be important for statistical analysis to determine the minimal requirement of our strategies which may be equivalent to or replace COVID-19 vaccines.

关键词： Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus Disease 2019 (COVID-19) Omicron Variant Risk Behaviors Protective Factors

Cultivating the unseen:Lessons from James Tiedje

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mLife 2023年第3期2卷 217-223页

作者： yoichi Kamagata National Institute of Advanced and Industrial Science and Technology(AIST) TsukubaJapan

In recounting *** ***'s outstanding research achievements spanning the past 55 years,it is easy to overlook his early and mid-career ***,his contribution to the aerobic degradation of pesticides and other chemicals,as well as methanogenic degradation of those compounds retains their *** researchers in environmental microbiology have gained invaluable knowledge from these studies,which have been applied to the elucidation of previously uncultivated microorganisms.

关键词： cultivated gained pesticides

Characteristics of glucose change in diabetes mellitus generalized through continuous wavelet transform processing:A preliminary study

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World Journal of Diabetes 2023年第10期14卷 1562-1572页

作者： yoichi Nakamura Shinya Furukawa Cardiovascular Medicine&Diabetology Specified Clinic of Soyokaze CardioVascular Medicine and Diabetes CareMatsuyama 790-0026EhimeJapan Health Services Center Ehime UniversityMatsuyama 790-8577EhimeJapan

BACKGROUND The continuous glucose monitoring(CGM)system has become a popular evaluation tool for glucose fluctuation,providing a detailed description of glucose change *** hypothesized that glucose fluctuations may contain specific information on differences in glucose change between type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM),despite similarities in change patterns,because of different *** Fourier transform,continuous wavelet transform(CWT)is able to simultaneously analyze the time and frequency domains of oscillating *** To investigate whether CWT can detect glucose fluctuations in *** The 60-d and 296-d glucose fluctuation data of patients with T1DM(n=5)and T2DM(n=25)were evaluated *** data obtained every 15 min for 356 d were *** were assessed by CWT with Morlet form(n=7)as the mother *** methodology was employed to search for limited frequency glucose fluctuation in the daily glucose *** frequency and enclosed area(0.02625 scalogram value)of 18 emerged signals were *** specificity for T1DM was evaluated through multiple regression analysis using items that demonstrated significant differences between them as explanatory *** The high frequency at midnight(median:75 Hz,cycle time:19 min)and middle frequency at noon(median:45.5 Hz,cycle time:32 min)were higher in T1DM vs T2DM(median:73 and 44 Hz;P=0.006 and 0.005,respectively).The area of the>100 Hz zone at midnight to forenoon was more frequent and larger in T1DM vs *** a day,the lower frequency zone(15-35 Hz)was more frequent and the area was larger in T2DM than in *** threedimensional scatter diagrams,which consist of the time of day,frequency,and area of each signal after CWT,revealed that high frequency signals belonging to T1DM at midnight had a loose distribution of wave cycles that were 17-24 *** analysis revealed that the high frequency signal at midnight could c

关键词： Continuous glucose monitoring Pathophysiology Fourier,Pseudo-frequency Contour map Scalogram matrix

Saturated hydraulic conductivity of compacted bentonite-sand mixtures before and after gas migration in artificial seawater

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第1期15卷 216-226页

作者： Yasutaka Watanabe Shingo Yokoyama Misato Shimbashi yoichi Yamamoto Takahiro Goto Sustainable System Research Laboratory Central Research Institute of Electric Power IndustryChibaJapan Science and Technology Department Nuclear Waste Management Organization of JapanTokyoJapan

To understand the self-healing property of an engineered barrier for radioactive waste disposal,the hydraulic conductivity of compacted bentoniteesand mixtures saturated with artificial seawater(SW)before and after gas migration was ***-and Ca-bentonites were mixed with fine sand at a ratio of 70%bentonite in dry *** aspects were considered during the experiment:the hydraulic conductivity of the specimen that was resaturated after gas migration and the distribution of water content immediately after gas migration to study gas migration *** gas migrated through the entire cross-section of the specimen,and gas breakthrough occurred in the equilibrium swelling pressure range ***,the gas flow rate reached a sufficient large value when the gas pressure was approximately twice the equilibrium axial pressure(the sum of swelling and confining pressures),which excluded the back *** the gas migration pathway was not visible when the specimen was observed immediately after gas migration,the water content distribution showed that several parts of the specimen with lower water content were connected in the direction of gas *** resaturation,the change in permeability was within a limited rangedtwo to three times larger than that before gas migration for each type of bentonite in *** slight change suggests that gas migration creates a pore structure that cannot be sealed via crystalline swelling of montmorillonite in SW,even if highly compacted bentonite is used under a constant-volume condition.

关键词： Bentonite Gas migration Hydraulic conductivity Seawater(SW) Self-healing

Plant functional remote sensing and smart farming applications

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International Journal of Agricultural and Biological Engineering 2022年第4期15卷 1-6页

作者： Kenji Omasa Eiichi Ono Yasuhiro Ishigami Yo Shimizu yoichi Araki Faculty of Agriculture Takasaki University of Health and WelfareGunma 370-0033Japan The University of Tokyo Tokyo 113-8657Japan

Plants have the distinctive 3D spatial structure that varies among organs,species and communities,and the spatial structure changes as they interact with their *** functions linked to fundamental biological activities such as transpiration,photosynthesis,and growth are also affected by the spatial structure and the *** order to promote smart farming using information and communication technology(ICT),it is necessary to measure and utilize information at the cell-organ of plants to the individual and the community levels and the environments in two or even three ***,this paper introduced the outline of remote sensing of plant functioning and examples of the 3D remote sensing from relatively short distances using drones and ground *** quality control of rice in the paddy field and chlorophyll fluorescence imaging for photosynthetic diagnosis were also *** addition,a field smart farm and a smart greenhouse,which heavily utilize ICT,built at Takasaki University of Health and Welfare in Gunma,Japan,were also introduced.

关键词： remote sensing smart farming smart greenhouse IoT ICT image analysis

Now and future of mouse mutagenesis for human disease models

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Journal of Genetics and Genomics 2010年第9期37卷 559-572页

作者： yoichi Gondo Mutagenesis and Genomics Team RIKEN Bio Resource Center

One of the major objectives of the Human Genome Project is to understand the biological function of the gene and genome as well as to develop clinical applications for human diseases. For this purpose, the experimental validations and preclinical trails by using animal models are indispensable. The mouse （Mus musculus） is one of the best animal models because genetics is well established in the mouse and embryonic manipulation technologies are also well developed. Large-scale mouse mutagenesis projects have been conducted to develop various mouse models since 1997. Originally, the phenotype-driven mutagenesis with N-ethyl-N-nitrosourea （ENU） has been the major efforts internationally then knockout/conditional mouse projects and gene-driven mutagenesis have been following. At the beginning, simple monogenic traits in the experimental condition have been elucidated. Then, more complex traits with variety of environmental interactions and gene-to-gene interactions （epistasis） have been challenged with mutant mice. In addition, chromosomal substitution strains and collaborative cross strains are also available to elucidate the complex traits in the mouse. Altogether, mouse models with mutagenesis and various laboratory strains will accelerate the studies of functional genomics in the mouse as well as in human.

关键词： mutagenesis functional genomics reverse genetics model animal quantitative trait epistasis