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The deterministic condition for the ground reaction force acting point on the combined knee valgus and tibial internal rotation moments in early phase of cutting maneuvers in female athletes

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Journal of Sport and Health Science 2024年第3期13卷 376-386页

作者： Issei Ogasawara Ken Ohta Gajanan S.Revankar Shoji Konda yohei Shimokochi Hideyuki Koga Ken Nakata Department of Health and Sport Sciences Graduate School of MedicineOsaka UniversityToyonaka 560-0043Japan Sports Sensing Co. LTD.Fukuoka 815-0035Japan Department of Neurology Graduate School of MedicineOsaka UniversitySuita 565-0871Japan Department of Health and Sport Management Osaka University of Health and Sport SciencesSennan-gun 590-0496Japan Department of Joint Surgery and Sports Medicine Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityBunkyo-ku 113-8519Japan

Background:Combined knee valgus and tibial internal rotation(VL+IR)moments have been shown to stress the anterior cruciate ligament(ACL)in several in vitro cadaveric *** utilize this knowledge for non-contact ACL injury prevention in sports,it is necessary to elucidate how the ground reaction force(GRF)acting point(center of pressure(CoP))in the stance foot produces combined knee VL+IR moments in risky maneuvers,such as ***,the effects of the GRF acting point on the development of the combined knee VL+IR moment in cutting are still ***:We first established the deterministic mechanical condition that the CoP position relative to the tibial rotational axis differentiates the GRF vector’s directional probability for developing the combined knee VL+IR moment,and theoretically predicted that when the CoP is posterior to the tibial rotational axis,the GRF vector is more likely to produce the combined knee VL+IR moment than when the CoP is anterior to the tibial rotational ***,we tested a stochastic aspect of our theory in a lab-controlled in vivo *** females performed 60˚cutting under forefoot/rearfoot strike conditions(10 trials each).The positions of lower limb markers and GRF data were measured,and the knee moment due to GRF vector was *** trials were divided into anterior-and posterior-CoP groups depending on the CoP position relative to the tibial rotational axis at each 10 ms interval from 0 to 100 ms after foot strike,and the occurrence rate of the combined knee VL+IR moment was compared between trial ***:The posterior-CoP group showed significantly higher occurrence rates of the combined knee VL+IR moment(maximum of 82.8%)at every time point than those of the anterior-CoP trials,as theoretically predicted by the deterministic mechanical ***:The rearfoot strikes inducing the posterior CoP should be avoided to reduce the risk of non-contact ACL injury associated with the com

关键词： Center of pressure Deterministic condition Foot strike pattern Injury mechanism Moment of ground reaction force

In Vivo Improvements in Facial Appearance and in Vitro Changes in Gene Expression Using a Topical Formulation Designed to Repair Environmentally Induced DNA Damage

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Journal of Cosmetics, Dermatological Sciences and Applications 2024年第2期14卷 141-173页

作者： Amaryllis Aganahi Richard Parker yohei Tanaka RATIONALE Kyneton Australia Clinica Tanaka Plastic Reconstructive Surgery and Anti-aging Center Matsumoto Japan

Background: While sunscreen has been accepted as a mainline defence against photodamage from ultraviolet, visible light and near-infrared radiation, there appears to be a lack of research into photorepair. The concept of protecting the skin during the day and repairing cellular damage at night is intuitive, yet specific strategies revolving around combinations of proven reparative active ingredients remain unelucidated. Purpose: To investigate the efficacy of a solar repair Formulation following ultraviolet and environmental exposure in order to improve overall skin health and appearance through three hypotheses: The Formulation increases expression of DNA repair mechanisms markers;The Formulation enhances overall skin appearance through reducing signs of inflammation, elevating hydration, reinforcing skin firmness and amplifying radiance;In-Vivo efficacy test results are aligned with measured gene expression changes. Methods: The Formulation (#6NIC1.V1.1-1) was tested for: In-vitro LDH cytotoxicity activity, In-vitro qPCR gene expression with and without ultraviolet exposure on a reconstructed 3-dimensional skin model, and In-Vivo efficacy study on a panel of 22 participants objectively and subjectively. Results: Skin radiance, firmness, hydration, redness, and inflammation are significantly improved after In-Vivo skin exposure to the Formulation and environmental challenges such as ultraviolet radiation. These outcomes were confirmed by in-vitro genetic testing on a reconstructed human skin model. Conclusion: The studies allowed us to identify and group results in four main skin functions that were significantly enhanced following the application of the Formulation: firmness, hydration, radiance and soothing.

关键词： Photoprotection Photorepair DNA Repair Anti-Photoaging Gene Expression Antioxidant Rejuvenation

Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy

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World Journal of Gastroenterology 2024年第14期30卷 2006-2017页

作者： Kazuhiro Takahashi Masahiko Gosho Yoshihiro Miyazaki Hiromitsu Nakahashi Osamu Shimomura Kinji Furuya Manami Doi yohei Owada Koichi Ogawa Yusuke Ohara Yoshimasa Akashi Tsuyoshi Enomoto Shinji Hashimoto Tatsuya Oda Department of Gastrointestinal and Hepatobiliary-Pancreatic Surgery University of TsukubaTsukuba 3058-575IbarakiJapan Department of Biostatistics University of TsukubaTsukuba 3058-575IbarakiJapan

BACKGROUND The success of liver resection relies on the ability of the remnant liver to *** of the knowledge regarding the pathophysiological basis of liver regeneration comes from rodent studies,and data on humans are ***,there is limited knowledge about the preoperative factors that influence postoperative *** To quantify postoperative remnant liver volume by the latest volumetric software and investigate perioperative factors that affect posthepatectomy liver *** A total of 268 patients who received partial hepatectomy were *** were grouped into right hepatectomy/trisegmentectomy(RH/Tri),left hepa-tectomy(LH),segmentectomy(Seg),and subsegmentectomy/nonanatomical hepatectomy(Sub/Non)*** regeneration index(RI)and late rege-neration rate were defined as(postoperative liver volume)/[total functional liver volume(TFLV)]×100 and(RI at 6-months-RI at 3-months)/RI at 6-months,*** lower 25th percentile of RI and the higher 25th percentile of late regeneration rate in each group were defined as“low regeneration”and“delayed regeneration”.“Restoration to the original size”was defined as regeneration of the liver volume by more than 90%of the TFLV at 12 months *** The numbers of patients in the RH/Tri,LH,Seg,and Sub/Non groups were 41,53,99 and 75,*** RI plateaued at 3 months in the LH,Seg,and Sub/Non groups,whereas the RI increased until 12 months in the RH/Tri *** to our multivariate analysis,the preoperative albumin-bilirubin(ALBI)score was an independent factor for low regeneration at 3 months[odds ratio(OR)95%CI=2.80(1.17-6.69),P=0.02;per 1.0 up]and 12 months[OR=2.27(1.01-5.09),P=0.04;per 1.0 up].Multivariate analysis revealed that only liver resection percentage[OR=1.03(1.00-1.05),P=0.04]was associated with delayed ***,multivariate analysis demonstrated that the preoperative ALBI score[OR=2.63(1.00-1.05),P=0.02;per 1.

关键词： Liver regeneration Albumin-bilirubin score Liver resection percentage Partial hepatectomy Human Regeneration index

Seismic assessment of two multi-tiered pagodas damaged by the 2015 Nepal earthquake

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Earthquake Engineering and Engineering Vibration 2021年第2期20卷 453-469页

作者： yohei Endo Toshikazu Hanazato Department of Architecture Shinshu University4-17-1 WakasatoNagano 380-8553Japan Department of Architecture Mie University1577 Kurimamachiya-chōTsuMie 514-8507MieJapan

A seismic assessment of two multi-tier pagodas by numerical analysis is presented *** Changu Narayan temple and the Kumbeshwar temple in Nepal are used as the case *** pagodas are built of brick masonry in earthen mortar,with timber columns and *** Changu Narayan temple is a two-tier pagoda,and was seriously damaged during the 2015 Gorkha *** Kumbeshwar temple is a five-tier pagoda,and its top-tier collapsed due to the Gorkha earthquake.A seismic assessment was carried out using finite element(FE)*** FE models were prepared,and dynamic identification tests and penetrometer tests were *** analysis and nonlinear dynamic analysis were performed as part of the seismic *** main shock of the 2015 Gorkha earthquake was considered as the input *** behavior between the two pagodas was compared with the collapse mechanisms and damage patterns observed in the actual *** comparison suggested common structural features of multi-tier *** study is dedicated to providing a better understanding of the seismic behavior of multi-tier pagoda-type structures and provides suggestions for their effective analysis.

关键词： masonry multi-tier pagoda seismic assessment nonlinear dynamic analysis FEM analysis

Evolution of the “Neutral” : Diverse Forms of Wide-Compatibility Haplotypes at the Locus for Reproductive Isolation

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Molecular Plant 2020年第4期13卷 539-540页

作者： yohei Koide Research Faculty of Agriculture Hokkaido UniversityKita 9 Nishi 9SapporoHokkaido 060-8589Japan

One of the biggest questions in evolutionary biology is how biological species *** biological species are groups of interbreeding natural populations reproductively isolated from other such groups(Mayer,1942),reproductive isolation is the key process of the *** various isolating barriers,postzygotic barriers ranging from maladaptation to inviability or sterility in the offspring have attracted biologists’attention because of the problem of the evolution of the“unfit”offspring.A clear model to solve this problem is the Dobzhansky-Muller(DM)model(Figure 1;Coyne and Orr,2004),in which incompatibilities are generally caused by an interaction between the genes that have functionally diverged in each population without selection opposing any intermediate step(Coyne and Orr,2004).

关键词： Figure Forms breeding

In Vivo Improvements in Facial Appearance and in Vitro Changes in Gene Expression Using a Topical Formulation Designed to Repair Environmentally Induced DNA Damage

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Synthesis and sintering of samarium rich SmS_x and its electrical property

Journal of Cosmetics, Dermatological Sciences and Applications（化妆品、皮肤病及应用期刊） 2024年第2期 141页

作者： Amaryllis Aganahi Richard Parker yohei Tanaka

来源：博看期刊评论

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Journal of Rare Earths 2016年第10期34卷 1042-1047页

作者： Liang Li Shinji Hirai yohei Tasaki Department of Materials Science and Engineering Muroran Institute of Technology

Non-stoichiometric samarium monosulfide（SmS_x, 0.55≤x≤1.2） was synthesized from Sm_2S_3 and SmH_3 at 1273 K for 3 h under vacuum. The influence of reaction ratio of Sm_2S_3 to SmH_3 on the fabrication of SmS_x was investigated. The fabrication of SmS required the molar ratio of Sm_2S_3 to SmH_3 above 1. Lattice parameter of synthetic SmS_x increased firstly and then decreased to saturate following with the addition of SmH_3 content. SmS_x compact was sintered at 1373 K by spark plasma sintering. Density of synthetic SmS_x was about 99% of theory density. Seebeck coefficient of n-type semiconductor Sm Sx decreased as temperature rose. The absolute value was distributed between 170–280 μV/K. The electrical resistivity of SmS_x（0.86≤x≤1.07） decreased with temperature increasing and showed similar temperature dependence. The surplus Sm which randomly distributed in the SmS_x（0.55≤x≤0.75） matrix led to a remarked reduction of electrical resistivity. The optimized power factor for SmS_（0.6） and Sm S_（0.75） could reach 1500 μW/（K^2·m） at 600 K.

关键词： samarium monosulfide SmH_3 Seebeck coefficient electrical resistivity rare earths

Large Eddy Simulation of Swirling Jet in a Bluff-Body Burner

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Journal of Thermal Science 2005年第1期14卷 28-33页

作者： yohei FUJIMOTO Yuzo INOKUCHI Nobuhiko YAMASAKI Department of Aeronautics and Astronautics Kyushu-University 6-10-1HakozakiHigashikuFukuoka812-8581JapanDepartment of Aeronautics and Astronautics Kyushu-University 6-10-1HakozakiHigashikuFukuoka812-8581JapanDepartment of Aeronautics and Astronautics Kyushu-University 6-10-1HakozakiHigashikuFukuoka812-8581Japan

The large eddy simulation (LES) is applied to an unconfined swirling flow of an air surrounding a bluff-body having a central jet of air, and the complicated flowfield that involves the recirculation and vortex breakdown is investigated. The Smagorinsky model is used as the sub-grid scale model. The results of the present numerical simulation are compared with the experimental data of the mean and stochastic root mean square (RMS) variations of two velocity components. Although the inflow conditions are specified in a simple manner, the obtained numerical results are in reasonable agreement with the experiments, except for a part of RMS variation values near downstream of the bluff body. The present numerical calculations can successfully reproduce the two characteristics of the flow, i.e., an upstream recirculation zone established just downstream of the burner plane and the additional recirculation zone established at the more downstream location.

关键词： large eddy simulation swirl bluff-body recirculation.

Computational fluid dynamics simulation of Hyperloop pod predicting laminar–turbulent transition

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Railway Engineering Science 2020年第1期28卷 97-111页

作者： Nathalie Nick yohei Sato Department of Mechanical and Process Engineering Swiss Federal Institute of TechnologyETH ZurichLEO B 9.1Leonhardstrasse 278092 ZurichSwitzerland Nuclear Energy and Safety Research Division Paul Scherrer InstituteForschungsstrasse 1115232 Villigen PSISwitzerland

Three-dimensional compressible flow simulationswere conducted to develop a Hyperloop pod. Thenovelty is the usage of Gamma transition model, in whichthe transition from laminar to turbulent flow can be ***, a mesh dependency study was undertaken,showing second-order convergence with respect to themesh refinement. Second, an aerodynamic analysis for twodesigns, short and optimized, was conducted with thetraveling speed 125 m/s at the system pressure 0.15 *** concept of the short model was to delay the transitionto decrease the frictional drag;meanwhile that of theoptimized design was to minimize the pressure drag bydecreasing the frontal area and introduce the transitionmore toward the front of the pod. The computed resultsshow that the transition of the short model occurred moreon the rear side due to the pod shape, which resulted in 8%smaller frictional drag coefficient than that for the optimizedmodel. The pressure drag for the optimized designwas 24% smaller than that for the short design, half ofwhich is due to the decrease in the frontal area, and theother half is due to the smoothed rear-end shape. The totaldrag for the optimized model was 14% smaller than that forthe short model. Finally, the influence of the systempressure was investigated. As the system pressure and theReynolds number increase, the frictional drag coefficientincreases, and the transition point moves toward the front,which are the typical phenomena observed in the transitionregime.

关键词： Computational fluid dynamics(CFD) Drag Subsonic compressible flow Hyperloop Laminar-turbulent transition