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重庆市实用性村庄规划编制技术探索

城市建筑 2023年第2期20卷 34-37页

作者：何汇域宋依芸江汶静张维重庆市规划和自然资源调查监测院

在“乡村振兴”战略和新时代国土空间规划体系背景下,重庆市已有的村庄规划编制技术标准已不能与之适应。为进一步科学有序地指导重庆市村庄规划编制工作,有效助力“乡村振兴”,本文在深入分析新时代对村庄规划提出的新要求的前提下,深... 详细信息

在“乡村振兴”战略和新时代国土空间规划体系背景下,重庆市已有的村庄规划编制技术标准已不能与之适应。为进一步科学有序地指导重庆市村庄规划编制工作,有效助力“乡村振兴”,本文在深入分析新时代对村庄规划提出的新要求的前提下,深入分析调研,找准当前规划编制痛点、难点,紧扣重庆市村庄规划编制面临的现实问题,同时学习借鉴其他省市已出台的村庄规划编制技术标准,从五个方面提出重庆市实用性村庄规划编制技术响应,以期为全市推进村庄规划编制提供依据和借鉴。

关键词：实用性村庄规划编制技术重庆市

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金属硅中氮含量分析方法研究

山东化工 2018年第22期47卷 69-70页

作者：孙海峰周海收陈彩霞宋义运北京有色金属研究总院国标(北京)检验认证有限公司北京100088

研究了ONH836氧氮氢测定仪测定金属硅中氮含量的测定方法。通过正交试验分析了主要因素及水平对测定结果的影响,确定了最佳分析条件。最佳分析条件为采用座坩埚,称样质量为0. 05～0. 15g,分析功率为4500W。该方法测定下限为0. 0020%。... 详细信息

研究了ONH836氧氮氢测定仪测定金属硅中氮含量的测定方法。通过正交试验分析了主要因素及水平对测定结果的影响,确定了最佳分析条件。最佳分析条件为采用座坩埚,称样质量为0. 05～0. 15g,分析功率为4500W。该方法测定下限为0. 0020%。分析了该测试方法的精密度及准确度。采用该方法测定硅中氮得到的RSD <6%;加标回收率在92%～112%之间,满足分析测试准确度要求。

关键词：金属硅氮含量助溶剂正交试验

The First Discovery of Colusite in the Tiegelongnan Supper-large Cu(Au, Ag) Deposit and Significance for the Genesis of the Deposit

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Acta Geologica Sinica(English Edition) 2018年第1期92卷 400-401页

作者： WANG yiyun TANG Juxing song Yang LIN Bin WANG Qin College of Earth Science Chengdu University of Technology MLR Key Laboratory of Metallogeny and Mineral Resource Assessment Institute o Mineral ResourcesChinese Academy o Geological Science

Objective The Tiegelongnan deposit,located at Duolong ore district in western part of Bangong Co.-Nujiang metallogenic belt,is the first super-large Cu(Au,Ag)deposit with typical features of high-sulfidation epitherma...

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Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass

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Journal of Materials Science & Technology 2014年第12期30卷 1255-1261页

作者： Jingfeng Wang Yang Li song Huang yiyun Wei Xingfeng Xi Kaiyong Cai Fusheng Pan National Engineering Research Center for Magnesium Alloys College of Materials Science and Engineering Chongqing University China Academy of Engineering Physics College of Bioengineering Chongqing University

The micro-alloying effects of Y on the microstructure, mechanical properties, and bio-corrosion behavior of Mg69-xZn27Ca4Yx（x= 0, 1, 2 at.%） alloys were investigated through X-ray diffraction, compressive tests,electrochemical treatments, and immersion tests. The Mg69Zn27Ca4 alloy was found to be absolutely amorphous, and its glass-forming ability decreased with the addition of Y. The Mg68Zn27Ca4Y1 alloy exhibited an ultrahigh compressive strength above 1010 MPa as well as high capacity for plastic strain above 3.1%.Electrochemical and immersion tests revealed that these Y-doped MgeZ neC a alloys had good bio-corrosion resistance in simulated body fluid（SBF） at 37℃. The results of the cytotoxicity test showed high cell viabilities for these alloys, which means good bio-compatibility.

关键词： Mg alloy Microstructure Mechanical properties Bio-corrosion resistance Bio-compatibility

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中药熏香制剂抑菌环实验研究

实用中医内科杂志 2024年第5期38卷 81-83页

作者：宋奕鋆袁睿裴天蕊金佳琦李雨蓉韩宇辽宁中医药大学辽宁沈阳110847

目的开展中药熏香防疫研究,研制具有高效、安全、环保的中药熏香制剂,证实其具有抑菌性能。方法采用苍术、艾叶、桂枝为主要原料,经水蒸气蒸馏法得到混合挥发油,稀释成不同浓度的制剂,采用抑菌环试验对金黄色葡萄球菌与大肠杆菌的效... 详细信息

目的开展中药熏香防疫研究,研制具有高效、安全、环保的中药熏香制剂,证实其具有抑菌性能。方法采用苍术、艾叶、桂枝为主要原料,经水蒸气蒸馏法得到混合挥发油,稀释成不同浓度的制剂,采用抑菌环试验对金黄色葡萄球菌与大肠杆菌的效果进行观察。结果根据实验结果,中药熏剂对金黄色葡萄球菌与大肠杆菌有明显的抑菌环,具有较强的抑菌和杀菌作用。结论中药熏香的消毒效果明确,该制剂具有良好的抑菌能力。

关键词：中药熏香预防抑菌作用

Targeted and intracellular delivery of protein therapeutics by a boronated polymer for the treatment of bone tumors

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Bioactive Materials 2022年第1期7卷 333-340页

作者： Yang Yan Lei Zhou Zhengwang Sun Dianwen song yiyun Cheng Shanghai Key Laboratory of Regulatory Biology School of Life SciencesEast China Normal UniversityShanghai200241China Department of Orthopedics Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Musculoskeletal Oncology Fudan University Shanghai Cancer CenterShanghai200032China

The treatment of malignant bone tumors by chemotherapeutics often receives poor therapeutic response due to the specific physiological bone environment,and thus calls for the development of new therapeutic ***,we reported a bone-targeted protein nanomedicine for this ***,a toxin protein,was co-assembled with a boronated polymer for intracellular protein delivery,and the formed nanoparticles were further coated with an anionic polymer poly(aspartic acid)to shield the positive charges on nanoparticles and provide the bone targeting *** prepared ternary complex nanoparticles showed high bone accumulation both in vitro and in vivo,and could reverse the surface charge property from negative to positive after locating at tumor site triggered by tumor extracellular *** boronated polymer in the de-shielded nanoparticles further promote intracellular delivery of saporin into tumor cells,exerting the anticancer activity of saporin by inactivation of *** a result,the bone-targeted and saporin-loaded nanomedicine could kill cancer cells at a low saporin dose,and efficiently prevented the progression of osteosarcoma xenograft tumors and bone metastatic breast cancer in *** study provides a facile and promising strategy to develop protein-based nanomedicines for the treatment of malignant bone tumors.

关键词： Boronated polymer Dendrimers Intracellular protein delivery Bone targeting Cancer therapy

Screening and pilot-scale evaluation of a highly efficient pesticide-degrading Pseudomonas *** BL5

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Chinese Journal of Chemical Engineering 2024年第10期74卷 287-294页

作者： Rui Chen Xinyu Zuo He Bai Ruolin Qin Zhiguo Chen yiyun Liu Wenqing Cao Jingpeng song Xiaoqiang Jia Department of Biochemical Engineering School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Tianjin Huakan Environmental Protection Technology Co. Ltd.Tianjin 300170China Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China

The widespread use of pesticides has caused serious harm to ecosystems,necessitating effective and environmentally friendly treatment *** stands out as a promising approach for pollutant treatment,wherein the metabolic activities of microorganisms can transform toxic pesticides into compounds with lower or no *** this study,we obtained eight pesticide-degrading strains from pesticide-contaminated sites through continuous enrichment and *** highly efficient pesticide-degrading strains(degradation ratios exceeding 80%)were *** them,Pseudomonas ***5 exhibited the strongest growth(exceeding 10^(9) CFU·ml^(-1))and outstanding degradation of benzene derivatives and chlorinated hydrocarbons at both laboratory and pilot scales,with degradation ratios exceeding 98%and 99.6%,*** research provides new tools and insights for the bioremediation of pesticide-related pollutants.

关键词： Pesticides Pilot-scale Degradation Remediation Pseudomonas sp. Benzene

社区卫生服务中心护士对“互联网+护理服务”的意愿调查及影响因素分析

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生命科学仪器 2024年第6期22卷 240-243页

作者：张晓辰刘凤珍孙晓兰刘丹凤徐栋宋依云上海中医药大学附属七宝社区卫生服务中心护理部

目的调查分析社区卫生服务中心护士对“互联网+护理服务”的意愿及影响因素。方法选择2024年1月至2024年6月上海市闵行区14家社区卫生服务中心的196名护士进行调查，观察其对“互联网+护理服务”的意愿率，分析护士一般资料与意愿率... 详细信息

目的调查分析社区卫生服务中心护士对“互联网+护理服务”的意愿及影响因素。方法选择2024年1月至2024年6月上海市闵行区14家社区卫生服务中心的196名护士进行调查，观察其对“互联网+护理服务”的意愿率，分析护士一般资料与意愿率之间的关系。在14家社区卫生服务中心参与调查的护士中随机各抽取1名进行焦点小组访谈。结果 196名护士“互联网+护理服务”意愿率为54.08%。不同学历、职称护士的“互联网+护理服务”意愿率对比，P>0.05;男性护士意愿率高于女性，P<0.05;30岁及以上护士的意愿率更高，P<0.05;5～14年护士的“互联网+护理服务”意愿率更高，P<0.05;合同制护士的“互联网+护理服务”意愿率更高，P<0.05;其中已婚护士的“互联网+护理服务”意愿率更高，P<0.05;≥2个子女护士的“互联网+护理服务”意愿率更高，P<0.05;认知良好护士的“互联网+护理服务”意愿率更高，P<0.05。结论闵行区社区卫生服务中心护士对“互联网+护理服务”的意愿率较低。性别、年龄、工作年限、用工方式、婚姻状况、子女数量、对“互联网+护理服务”的认知等均可影响社区卫生服务中心护士对“互联网+护理服务”的意愿率。访谈后的主题凝练分别为社区护理人力资源不足、担忧人身安全、护理难度大、对绩效分配不满意。

关键词：互联网+护理服务社区卫生服务中心护士意愿

Scytosiphon lomentaria fucoidan alleviates alcohol-induced liver injury in mice via the modulation of gut microbiota and bile acid-FXR/AMPK and NF-κB pathways

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Food Science and Human Wellness 2024年

作者： yiyun Sun Qiuyue Men Xiaomeng Ren Xiaoming Guo Shuang song Chunqing Ai School of Food Science and Technology， National Engineering Research Center of Seafood， Dalian Polytechnic University Shenzhen Key Laboratory of Food Nutrition and Health， Institute for Advanced Study， Shenzhen University National & Local Joint Engineering Laboratory for Marine Bioactive Polysaccharide Development and Application， Dalian Polytechnic University

Alcohol intake is associated with increased mortality worldwide， particularly liver diseases， making it imperative to explore innovative strategies for managing alcohol-related liver disease. In this study， the efficacy of Scytosiphon lomentaria fucoidan (SLF) in alleviating alcohol-induced liver injury was evaluated in a mouse model. It showed that SLF increased body weight and colon length， while reducing liver index， serum lipid， alanine aminotransferase， and aspartate aminotransferase in alcohol-treated mice. SLF inhibited inflammatory response in the liver by reducing inflammatory infiltration and the levels of pro-inflammatory cytokines. It can be associated with the alleviation of oxidative stress and the inhibition of the nuclear factor-κB pathway. SLF modulated alcohol-induced dysbiosis of gut microbiota， including a reduction in Bacteroidetes and Proteobacteria， and improved metabolites profile， primarily affecting short chain fatty acids and amino acids metabolism. In addition， SLF reduced the level of total bile acids， regulated the profile of bile acids， and increased the levels of farnesoid X receptor (FXR) and AMP-activated protein kinase (AMPK)， suggesting that SLF can alleviate alcohol-induced liver injury by regulating bile acid-FXR/AMPK pathway. This study suggests that SLF holds the potential to alleviate the adverse effect of alcohol on the liver via the gut-liver axis.

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